Human Phenotype Ontology 
Grandparent Node:
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Hypohidrosis or hyperhidrosis (HP:0007550)help
Parent Node:
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Abnormal skin morphology of the palm (HP:0040211)help
Parent Node:
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Hyperhidrosis (HP:0000975)help
..Starting node
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Palmar hyperhidrosis (HP:0006089)help
Term ID: 6089
Name: Palmar hyperhidrosis
Synonym: Excessive sweating of hands
Definition:
Comments:
Reference: HP:0006089
Genes and Diseases:
 
       Child Nodes:
........expandPalmoplantar hyperhidrosis (HP:0007410) help

 Sister Nodes: 
..expandEpisodic hyperhidrosis (HP:0001069) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0006089HP:0006089Palmar hyperhidrosis0CDSN CL E G H10411802OMIM:270300Peeling skin syndrome 17
HP:0006089HP:0006089Palmar hyperhidrosis0CFTR CL E G H10801884ORPHA:498359Aquagenic palmoplantar keratoderma1371
HP:0006089HP:0006089Palmar hyperhidrosis0CTSB CL E G H15082527OMIM:148370Keratolytic winter erythema1
HP:0006089HP:0006089Palmar hyperhidrosis0KRT16 CL E G H38686423ORPHA:2309Pachyonychia congenita27
HP:0006089HP:0006089Palmar hyperhidrosis0KRT17 CL E G H38726427ORPHA:2309Pachyonychia congenita23
HP:0006089HP:0006089Palmar hyperhidrosis0KRT17 CL E G H38726427OMIM:167210Pachyonychia congenita 223
HP:0006089HP:0006089Palmar hyperhidrosis0KRT6A CL E G H38536443ORPHA:2309Pachyonychia congenita41
HP:0006089HP:0006089Palmar hyperhidrosis0KRT6B CL E G H38546444ORPHA:2309Pachyonychia congenita4
HP:0006089HP:0006089Palmar hyperhidrosis0LAMB3 CL E G H39146490OMIM:226650Epidermolysis bullosa, junctional, Non-Herlitz type.167
HP:0006089HP:0006089Palmar hyperhidrosis0MBTPS2 CL E G H5136015455ORPHA:659Mutilating palmoplantar keratoderma with periorificial keratotic plaques22
HP:0006089HP:0006089Palmar hyperhidrosis0PERP CL E G H6406517637ORPHA:659Mutilating palmoplantar keratoderma with periorificial keratotic plaques
HP:0006089HP:0006089Palmar hyperhidrosis0PLAA CL E G H93739043OMIM:617527Neurodevelopmental disorder with progressive microcephaly, spasticity, and brain anomalies3
HP:0006089HP:0006089Palmar hyperhidrosis0RSPO1 CL E G H28465421679OMIM:610644Palmoplantar hyperkeratosis with squamous cell carcinoma of skin and 46,xx sex reversal3
HP:0006089HP:0006089Palmar hyperhidrosis0SERPINB7 CL E G H871013902OMIM:615598Palmoplantar keratoderma, Nagashima type4
HP:0006089HP:0006089Palmar hyperhidrosis0TRPV3 CL E G H16251418084ORPHA:659Mutilating palmoplantar keratoderma with periorificial keratotic plaques151
HP:0006089HP:0006089Palmar hyperhidrosis0WNT10A CL E G H8032613829OMIM:257980Odontoonychodermal dysplasia71
HP:0006089HP:0006089Palmar hyperhidrosis0WNT10A CL E G H8032613829OMIM:150400Tooth agenesis, selective, 471
HP:0006089HP:0007410Palmoplantar hyperhidrosis1CDSN CL E G H10411802OMIM:270300Peeling skin syndrome 17
HP:0006089HP:0007410Palmoplantar hyperhidrosis1CFTR CL E G H10801884ORPHA:498359Aquagenic palmoplantar keratodermaHP:0040282 - Frequent1371
HP:0006089HP:0007410Palmoplantar hyperhidrosis1CTSB CL E G H15082527OMIM:148370Keratolytic winter erythema.1
HP:0006089HP:0007410Palmoplantar hyperhidrosis1KRT16 CL E G H38686423ORPHA:2309Pachyonychia congenitaHP:0040282 - Frequent27
HP:0006089HP:0007410Palmoplantar hyperhidrosis1KRT17 CL E G H38726427ORPHA:2309Pachyonychia congenitaHP:0040282 - Frequent23
HP:0006089HP:0007410Palmoplantar hyperhidrosis1KRT17 CL E G H38726427OMIM:167210Pachyonychia congenita 2.23
HP:0006089HP:0007410Palmoplantar hyperhidrosis1KRT6A CL E G H38536443ORPHA:2309Pachyonychia congenitaHP:0040282 - Frequent41
HP:0006089HP:0007410Palmoplantar hyperhidrosis1KRT6B CL E G H38546444ORPHA:2309Pachyonychia congenitaHP:0040282 - Frequent4
HP:0006089HP:0007410Palmoplantar hyperhidrosis1MBTPS2 CL E G H5136015455ORPHA:659Mutilating palmoplantar keratoderma with periorificial keratotic plaquesHP:0040281 - Very frequent22
HP:0006089HP:0007410Palmoplantar hyperhidrosis1PERP CL E G H6406517637ORPHA:659Mutilating palmoplantar keratoderma with periorificial keratotic plaquesHP:0040281 - Very frequent
HP:0006089HP:0007410Palmoplantar hyperhidrosis1PLAA CL E G H93739043OMIM:617527Neurodevelopmental disorder with progressive microcephaly, spasticity, and brain anomalies3
HP:0006089HP:0007410Palmoplantar hyperhidrosis1RSPO1 CL E G H28465421679OMIM:610644Palmoplantar hyperkeratosis with squamous cell carcinoma of skin and 46,xx sex reversal.3
HP:0006089HP:0007410Palmoplantar hyperhidrosis1SERPINB7 CL E G H871013902OMIM:615598Palmoplantar keratoderma, Nagashima type.4
HP:0006089HP:0007410Palmoplantar hyperhidrosis1TRPV3 CL E G H16251418084ORPHA:659Mutilating palmoplantar keratoderma with periorificial keratotic plaquesHP:0040281 - Very frequent151
HP:0006089HP:0007410Palmoplantar hyperhidrosis1WNT10A CL E G H8032613829OMIM:257980Odontoonychodermal dysplasia.71
HP:0006089HP:0007410Palmoplantar hyperhidrosis1WNT10A CL E G H8032613829OMIM:150400Tooth agenesis, selective, 471


Genes (15) :CDSN CFTR CTSB KRT16 KRT17 KRT6A KRT6B LAMB3 MBTPS2 PERP PLAA RSPO1 SERPINB7 TRPV3 WNT10A

Diseases (12) :OMIM:270300 ORPHA:498359 OMIM:148370 ORPHA:2309 OMIM:167210 OMIM:226650 ORPHA:659 OMIM:617527 OMIM:610644 OMIM:615598 OMIM:257980 OMIM:150400
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.