Human Phenotype Ontology 
Grandparent Node:
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Abnormality of eye movement (HP:0000496)help
Parent Node:
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Abnormal saccadic eye movements (HP:0000570)help
..Starting node
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Slow saccadic eye movements (HP:0000514)help
Term ID: 514
Name: Slow saccadic eye movements
Synonym: Slow eye movements; Slow saccades; Slow visual tracking
Definition: An abnormally slow velocity of the saccadic eye movements.
Comments:
Reference: HP:0000514
Genes and Diseases:
 
       Child Nodes:
........expandSlowed horizontal saccades (HP:0007885) help

 Sister Nodes: 
..expandDysmetric saccades (HP:0000641) help
..expandHypermetric saccades (HP:0007338) help
..expandHypometric saccades (HP:0000571) help
..expandSquare-wave jerks (HP:0025402) help
InputHPO IDHPO termDistanceGeneGene id entrezDiseaseIdDiseaseNameDiseaseMIMConceptIDSourceTypical associationHGMD variantsClinVar variantsHGNC IDGeneMIM
 
HPO disease - gene - phenotype typical associations:
HP:0000514HP:0000514Slow saccadic eye movements0AFG3L2 CL E G H10939101109ORPHA1357315604581
HP:0000514HP:0000514Slow saccadic eye movements0AFG3L2 CL E G H10939101109ORPHA1349315604581
HP:0000514HP:0000514Slow saccadic eye movements0AFG3L2 CL E G H10939610246Spinocerebellar ataxia 28610246C1853249OMIM1357315604581
HP:0000514HP:0000514Slow saccadic eye movements0AFG3L2 CL E G H10939610246Spinocerebellar ataxia 28610246C1853249OMIM1349315604581
HP:0000514HP:0000514Slow saccadic eye movements0AGTPBP1 CL E G H23287618276618276618276OMIM16417258606830
HP:0000514HP:0000514Slow saccadic eye movements0ALS2 CL E G H57679607225Infantile-onset ascending hereditary spastic paralysis607225C2931441OMIM1644443606352
HP:0000514HP:0000514Slow saccadic eye movements0ALS2 CL E G H57679607225Infantile-onset ascending hereditary spastic paralysis607225C2931441OMIM1524443606352
HP:0000514HP:0000514Slow saccadic eye movements0ATP13A2 CL E G H23400306674ORPHA160930213610513
HP:0000514HP:0000514Slow saccadic eye movements0ATP13A2 CL E G H23400306674ORPHA148730213610513
HP:0000514HP:0000514Slow saccadic eye movements0ATP13A2 CL E G H23400606693Parkinson disease 9606693C1847640OMIM160930213610513
HP:0000514HP:0000514Slow saccadic eye movements0ATP13A2 CL E G H23400606693Parkinson disease 9606693C1847640OMIM148730213610513
HP:0000514HP:0000514Slow saccadic eye movements0ATP2B3 CL E G H492302500Spinocerebellar ataxia, X-linked 1302500C0796205OMIM1300816300014
HP:0000514HP:0000514Slow saccadic eye movements0ATP2B3 CL E G H492302500Spinocerebellar ataxia, X-linked 1302500C0796205OMIM1292816300014
HP:0000514HP:0000514Slow saccadic eye movements0ATXN1 CL E G H631098755ORPHA17810548601556
HP:0000514HP:0000514Slow saccadic eye movements0ATXN1 CL E G H631098755ORPHA17610548601556
HP:0000514HP:0000514Slow saccadic eye movements0ATXN1 CL E G H6310164400Spinocerebellar ataxia 1164400C0752120OMIM17810548601556
HP:0000514HP:0000514Slow saccadic eye movements0ATXN1 CL E G H6310164400Spinocerebellar ataxia 1164400C0752120OMIM17610548601556
HP:0000514HP:0000514Slow saccadic eye movements0ATXN2 CL E G H631198756ORPHA15210555601517
HP:0000514HP:0000514Slow saccadic eye movements0ATXN2 CL E G H631198756ORPHA15010555601517
HP:0000514HP:0000514Slow saccadic eye movements0ATXN2 CL E G H6311183090Spinocerebellar ataxia 2183090C0752121OMIM15210555601517
HP:0000514HP:0000514Slow saccadic eye movements0ATXN2 CL E G H6311183090Spinocerebellar ataxia 2183090C0752121OMIM15010555601517
HP:0000514HP:0000514Slow saccadic eye movements0ATXN7 CL E G H6314164500Spinocerebellar ataxia 7164500C0752125OMIM13910560607640
HP:0000514HP:0000514Slow saccadic eye movements0ATXN7 CL E G H6314164500Spinocerebellar ataxia 7164500C0752125OMIM13710560607640
HP:0000514HP:0000514Slow saccadic eye movements0ATXN8 CL E G H724066608768Spinocerebellar ataxia 8608768C1837454OMIM1232925613289
HP:0000514HP:0000514Slow saccadic eye movements0ATXN8OS CL E G H6315608768Spinocerebellar ataxia 8608768C1837454OMIM17610561603680
HP:0000514HP:0000514Slow saccadic eye movements0ATXN8OS CL E G H6315608768Spinocerebellar ataxia 8608768C1837454OMIM17210561603680
HP:0000514HP:0000514Slow saccadic eye movements0ELOVL5 CL E G H60481423296ORPHA15221308611805
HP:0000514HP:0000514Slow saccadic eye movements0ELOVL5 CL E G H60481423296ORPHA14921308611805
HP:0000514HP:0000514Slow saccadic eye movements0ELOVL5 CL E G H60481615957Spinocerebellar ataxia 38615957C4014812OMIM15221308611805
HP:0000514HP:0000514Slow saccadic eye movements0ELOVL5 CL E G H60481615957Spinocerebellar ataxia 38615957C4014812OMIM14921308611805
HP:0000514HP:0000514Slow saccadic eye movements0FBXO7 CL E G H25793171695ORPHA118313586605648
HP:0000514HP:0000514Slow saccadic eye movements0FBXO7 CL E G H25793171695ORPHA116113586605648
HP:0000514HP:0000514Slow saccadic eye movements0FBXO7 CL E G H25793260300Parkinson disease 15260300C1850100OMIM118313586605648
HP:0000514HP:0000514Slow saccadic eye movements0FBXO7 CL E G H25793260300Parkinson disease 15260300C1850100OMIM116113586605648
HP:0000514HP:0000514Slow saccadic eye movements0GJC2 CL E G H57165613206Spastic paraplegia 44, autosomal recessive613206C2750784OMIM122117494608803
HP:0000514HP:0000514Slow saccadic eye movements0GJC2 CL E G H57165613206Spastic paraplegia 44, autosomal recessive613206C2750784OMIM117417494608803
HP:0000514HP:0000514Slow saccadic eye movements0MRE11 CL E G H4361251347ORPHA112597230600814
HP:0000514HP:0000514Slow saccadic eye movements0MRE11 CL E G H4361251347ORPHA112587230600814
HP:0000514HP:0000514Slow saccadic eye movements0NOP56 CL E G H10528276198ORPHA14415911614154
HP:0000514HP:0000514Slow saccadic eye movements0NOP56 CL E G H10528276198ORPHA14315911614154
HP:0000514HP:0000514Slow saccadic eye movements0PDYN CL E G H5173101108ORPHA11598820131340
HP:0000514HP:0000514Slow saccadic eye movements0PDYN CL E G H5173101108ORPHA11448820131340
HP:0000514HP:0000514Slow saccadic eye movements0PDYN CL E G H5173610245Spinocerebellar ataxia 23610245C1853250OMIM11598820131340
HP:0000514HP:0000514Slow saccadic eye movements0PDYN CL E G H5173610245Spinocerebellar ataxia 23610245C1853250OMIM11448820131340
HP:0000514HP:0000514Slow saccadic eye movements0PEX2 CL E G H5828614867Peroxisome biogenesis disorder 5B614867C3542026OMIM13199717170993
HP:0000514HP:0000514Slow saccadic eye movements0PEX2 CL E G H5828614867Peroxisome biogenesis disorder 5B614867C3542026OMIM12549717170993
HP:0000514HP:0000514Slow saccadic eye movements0PIK3R5 CL E G H23533615217Ataxia-oculomotor apraxia 3615217C3554690OMIM14830035611317
HP:0000514HP:0000514Slow saccadic eye movements0PLD3 CL E G H23646617770SPINOCEREBELLAR ATAXIA 46617770C4540404OMIM12017158615698
HP:0000514HP:0000514Slow saccadic eye movements0PLD3 CL E G H23646617770SPINOCEREBELLAR ATAXIA 46617770C4540404OMIM11917158615698
HP:0000514HP:0000514Slow saccadic eye movements0SNCA CL E G H6622171695ORPHA116611138163890
HP:0000514HP:0000514Slow saccadic eye movements0SNCA CL E G H6622171695ORPHA115411138163890
HP:0000514HP:0000514Slow saccadic eye movements0TMEM240 CL E G H339453607454Spinocerebellar ataxia 21607454C1843891OMIM118625186616101
HP:0000514HP:0000514Slow saccadic eye movements0TMEM240 CL E G H339453607454Spinocerebellar ataxia 21607454C1843891OMIM117625186616101
HP:0000514HP:0000514Slow saccadic eye movements0VAMP1 CL E G H6843251282ORPHA19912642185880
HP:0000514HP:0000514Slow saccadic eye movements0VAMP1 CL E G H6843251282ORPHA18312642185880
HP:0000514HP:0000514Slow saccadic eye movements0VAMP1 CL E G H6843108600Ataxia, spastic, 1, autosomal dominant108600C1970107OMIM19912642185880
HP:0000514HP:0000514Slow saccadic eye movements0VAMP1 CL E G H6843108600Ataxia, spastic, 1, autosomal dominant108600C1970107OMIM18312642185880
HP:0000514HP:0007885Slowed horizontal saccades1AFG3L2 CL E G H10939101109ORPHA1357315604581
HP:0000514HP:0007885Slowed horizontal saccades1AFG3L2 CL E G H10939101109ORPHA1349315604581
HP:0000514HP:0007885Slowed horizontal saccades1AFG3L2 CL E G H10939610246Spinocerebellar ataxia 28610246C1853249OMIM1357315604581
HP:0000514HP:0007885Slowed horizontal saccades1AFG3L2 CL E G H10939610246Spinocerebellar ataxia 28610246C1853249OMIM1349315604581
HP:0000514HP:0007885Slowed horizontal saccades1AGTPBP1 CL E G H23287618276618276618276OMIM16417258606830
HP:0000514HP:0007885Slowed horizontal saccades1ALS2 CL E G H57679607225Infantile-onset ascending hereditary spastic paralysis607225C2931441OMIM1644443606352
HP:0000514HP:0007885Slowed horizontal saccades1ALS2 CL E G H57679607225Infantile-onset ascending hereditary spastic paralysis607225C2931441OMIM1524443606352
HP:0000514HP:0007885Slowed horizontal saccades1ATP13A2 CL E G H23400306674ORPHA160930213610513
HP:0000514HP:0007885Slowed horizontal saccades1ATP13A2 CL E G H23400306674ORPHA148730213610513
HP:0000514HP:0007885Slowed horizontal saccades1ATP13A2 CL E G H23400606693Parkinson disease 9606693C1847640OMIM160930213610513
HP:0000514HP:0007885Slowed horizontal saccades1ATP13A2 CL E G H23400606693Parkinson disease 9606693C1847640OMIM148730213610513
HP:0000514HP:0007885Slowed horizontal saccades1ATP2B3 CL E G H492302500Spinocerebellar ataxia, X-linked 1302500C0796205OMIM1300816300014
HP:0000514HP:0007885Slowed horizontal saccades1ATP2B3 CL E G H492302500Spinocerebellar ataxia, X-linked 1302500C0796205OMIM1292816300014
HP:0000514HP:0007885Slowed horizontal saccades1ATXN1 CL E G H631098755ORPHA17810548601556
HP:0000514HP:0007885Slowed horizontal saccades1ATXN1 CL E G H631098755ORPHA17610548601556
HP:0000514HP:0007885Slowed horizontal saccades1ATXN1 CL E G H6310164400Spinocerebellar ataxia 1164400C0752120OMIM17810548601556
HP:0000514HP:0007885Slowed horizontal saccades1ATXN1 CL E G H6310164400Spinocerebellar ataxia 1164400C0752120OMIM17610548601556
HP:0000514HP:0007885Slowed horizontal saccades1ATXN2 CL E G H631198756ORPHA15210555601517
HP:0000514HP:0007885Slowed horizontal saccades1ATXN2 CL E G H631198756ORPHA15010555601517
HP:0000514HP:0007885Slowed horizontal saccades1ATXN2 CL E G H6311183090Spinocerebellar ataxia 2183090C0752121OMIM15210555601517
HP:0000514HP:0007885Slowed horizontal saccades1ATXN2 CL E G H6311183090Spinocerebellar ataxia 2183090C0752121OMIM15010555601517
HP:0000514HP:0007885Slowed horizontal saccades1ATXN7 CL E G H6314164500Spinocerebellar ataxia 7164500C0752125OMIM13910560607640
HP:0000514HP:0007885Slowed horizontal saccades1ATXN7 CL E G H6314164500Spinocerebellar ataxia 7164500C0752125OMIM13710560607640
HP:0000514HP:0007885Slowed horizontal saccades1ATXN8 CL E G H724066608768Spinocerebellar ataxia 8608768C1837454OMIM1232925613289
HP:0000514HP:0007885Slowed horizontal saccades1ATXN8OS CL E G H6315608768Spinocerebellar ataxia 8608768C1837454OMIM17610561603680
HP:0000514HP:0007885Slowed horizontal saccades1ATXN8OS CL E G H6315608768Spinocerebellar ataxia 8608768C1837454OMIM17210561603680
HP:0000514HP:0007885Slowed horizontal saccades1ELOVL5 CL E G H60481423296ORPHA15221308611805
HP:0000514HP:0007885Slowed horizontal saccades1ELOVL5 CL E G H60481423296ORPHA14921308611805
HP:0000514HP:0007885Slowed horizontal saccades1ELOVL5 CL E G H60481615957Spinocerebellar ataxia 38615957C4014812OMIM15221308611805
HP:0000514HP:0007885Slowed horizontal saccades1ELOVL5 CL E G H60481615957Spinocerebellar ataxia 38615957C4014812OMIM14921308611805
HP:0000514HP:0007885Slowed horizontal saccades1FBXO7 CL E G H25793171695ORPHA118313586605648
HP:0000514HP:0007885Slowed horizontal saccades1FBXO7 CL E G H25793171695ORPHA116113586605648
HP:0000514HP:0007885Slowed horizontal saccades1FBXO7 CL E G H25793260300Parkinson disease 15260300C1850100OMIM118313586605648
HP:0000514HP:0007885Slowed horizontal saccades1FBXO7 CL E G H25793260300Parkinson disease 15260300C1850100OMIM116113586605648
HP:0000514HP:0007885Slowed horizontal saccades1GJC2 CL E G H57165613206Spastic paraplegia 44, autosomal recessive613206C2750784OMIM122117494608803
HP:0000514HP:0007885Slowed horizontal saccades1GJC2 CL E G H57165613206Spastic paraplegia 44, autosomal recessive613206C2750784OMIM117417494608803
HP:0000514HP:0007885Slowed horizontal saccades1MRE11 CL E G H4361251347ORPHA112597230600814
HP:0000514HP:0007885Slowed horizontal saccades1MRE11 CL E G H4361251347ORPHA112587230600814
HP:0000514HP:0007885Slowed horizontal saccades1NOP56 CL E G H10528276198ORPHA14415911614154
HP:0000514HP:0007885Slowed horizontal saccades1NOP56 CL E G H10528276198ORPHA14315911614154
HP:0000514HP:0007885Slowed horizontal saccades1PDYN CL E G H5173101108ORPHA11598820131340
HP:0000514HP:0007885Slowed horizontal saccades1PDYN CL E G H5173101108ORPHA11448820131340
HP:0000514HP:0007885Slowed horizontal saccades1PDYN CL E G H5173610245Spinocerebellar ataxia 23610245C1853250OMIM11598820131340
HP:0000514HP:0007885Slowed horizontal saccades1PDYN CL E G H5173610245Spinocerebellar ataxia 23610245C1853250OMIM11448820131340
HP:0000514HP:0007885Slowed horizontal saccades1PEX2 CL E G H5828614867Peroxisome biogenesis disorder 5B614867C3542026OMIM13199717170993
HP:0000514HP:0007885Slowed horizontal saccades1PEX2 CL E G H5828614867Peroxisome biogenesis disorder 5B614867C3542026OMIM12549717170993
HP:0000514HP:0007885Slowed horizontal saccades1PIK3R5 CL E G H23533615217Ataxia-oculomotor apraxia 3615217C3554690OMIM14830035611317
HP:0000514HP:0007885Slowed horizontal saccades1PLD3 CL E G H23646617770SPINOCEREBELLAR ATAXIA 46617770C4540404OMIM12017158615698
HP:0000514HP:0007885Slowed horizontal saccades1PLD3 CL E G H23646617770SPINOCEREBELLAR ATAXIA 46617770C4540404OMIM11917158615698
HP:0000514HP:0007885Slowed horizontal saccades1SNCA CL E G H6622171695ORPHA116611138163890
HP:0000514HP:0007885Slowed horizontal saccades1SNCA CL E G H6622171695ORPHA115411138163890
HP:0000514HP:0007885Slowed horizontal saccades1TMEM240 CL E G H339453607454Spinocerebellar ataxia 21607454C1843891OMIM118625186616101
HP:0000514HP:0007885Slowed horizontal saccades1TMEM240 CL E G H339453607454Spinocerebellar ataxia 21607454C1843891OMIM117625186616101
HP:0000514HP:0007885Slowed horizontal saccades1VAMP1 CL E G H6843251282ORPHA19912642185880
HP:0000514HP:0007885Slowed horizontal saccades1VAMP1 CL E G H6843251282ORPHA18312642185880
HP:0000514HP:0007885Slowed horizontal saccades1VAMP1 CL E G H6843108600Ataxia, spastic, 1, autosomal dominant108600C1970107OMIM19912642185880
HP:0000514HP:0007885Slowed horizontal saccades1VAMP1 CL E G H6843108600Ataxia, spastic, 1, autosomal dominant108600C1970107OMIM18312642185880
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0000514HP:0000514Slow saccadic eye movements0NOP56 CL E G H10528614153Spinocerebellar ataxia 36614153C3472711OMIM04415911614154
HP:0000514HP:0000514Slow saccadic eye movements0NOP56 CL E G H10528614153Spinocerebellar ataxia 36614153C3472711OMIM04315911614154
HP:0000514HP:0000514Slow saccadic eye movements0PRNP CL E G H5621157941ORPHA01469449176640
HP:0000514HP:0000514Slow saccadic eye movements0PRNP CL E G H5621157941ORPHA01319449176640
HP:0000514HP:0007885Slowed horizontal saccades1NOP56 CL E G H10528614153Spinocerebellar ataxia 36614153C3472711OMIM04415911614154
HP:0000514HP:0007885Slowed horizontal saccades1NOP56 CL E G H10528614153Spinocerebellar ataxia 36614153C3472711OMIM04315911614154
HP:0000514HP:0007885Slowed horizontal saccades1PRNP CL E G H5621157941ORPHA01469449176640
HP:0000514HP:0007885Slowed horizontal saccades1PRNP CL E G H5621157941ORPHA01319449176640


Genes (24) :AFG3L2 AGTPBP1 ALS2 ATP13A2 ATP2B3 ATXN1 ATXN2 ATXN7 ATXN8 ATXN8OS ELOVL5 FBXO7 GBA GJC2 MRE11 NOP56 PDYN PEX2 PIK3R5 PLD3 PRNP SNCA TMEM240 VAMP1

Diseases (32) :101109 610246 618276 607225 306674 606693 302500 98755 164400 98756 183090 164500 608768 423296 615957 171695 260300 613206 251347 276198 614153 101108 610245 614867 615217 617770 157941 607454 251282 108600 2072 231005
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.