Human Phenotype Ontology 
Grandparent Node:
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Anemia due to reduced life span of red cells (HP:0011895)help
Parent Node:
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Hemolytic anemia (HP:0001878)help
..Starting node
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Coombs-positive hemolytic anemia (HP:0004844)help
Term ID: 4844
Name: Coombs-positive hemolytic anemia
Synonym: Direct Coombs positive
Definition: A type of hemolytic anemia in which the Coombs test is positive.
Comments:
Reference: HP:0004844
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAutoimmune hemolytic anemia (HP:0001890) help
..expandChronic hemolytic anemia (HP:0004870) help
..expandCold-induced hemolysis (HP:0031484) help
..expandCompensated hemolytic anemia (HP:0004863) help
..expandCongenital hemolytic anemia (HP:0004804) help
..expandDrug-sensitive hemolytic anemia (HP:0004817) help
..expandEpisodic hemolytic anemia (HP:0004802) help
..expandExercise-induced hemolysis (HP:0005535) help
..expandFava bean-induced hemolytic anemia (HP:0004814) help
..expandHeinz body anemia (HP:0005511) help
..expandIncreased red cell hemolysis by shear stress (HP:0008269) help
..expandMacrocytic hemolytic disease (HP:0005524) help
..expandMicroangiopathic hemolytic anemia (HP:0001937) help
..expandNonspherocytic hemolytic anemia (HP:0001930) help
..expandSpontaneous hemolytic crises (HP:0005525) help
InputHPO IDHPO termDistanceGeneGene id entrezDiseaseIdDiseaseNameDiseaseMIMConceptIDSourceTypical associationHGMD variantsClinVar variantsHGNC IDGeneMIM
 
HPO disease - gene - phenotype typical associations:
HP:0004844HP:0004844Coombs-positive hemolytic anemia0CASP10 CL E G H843603909Autoimmune lymphoproliferative syndrome, type 2A603909C1858968OMIM192361500601762
HP:0004844HP:0004844Coombs-positive hemolytic anemia0FAS CL E G H355601859Autoimmune lymphoproliferative syndrome601859C1328840OMIM114216911920134637
HP:0004844HP:0004844Coombs-positive hemolytic anemia0FASLG CL E G H356601859Autoimmune lymphoproliferative syndrome601859C1328840OMIM1119811936134638
HP:0004844HP:0004844Coombs-positive hemolytic anemia0TNFRSF4 CL E G H7293615593Immunodeficiency 16615593C3810053OMIM1222211918600315
 
HPO disease - gene - phenotype less frequent non-typical associations:


Genes (4) :CASP10 FAS FASLG TNFRSF4

Diseases (3) :603909 601859 615593
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is June 2019 release.