Human Phenotype Ontology 
Grandparent Node:
expand
Supraventricular arrhythmia (HP:0005115)help
Parent Node:
expand
Atrial arrhythmia (HP:0001692)help
..Starting node
..expand
Atrial flutter (HP:0004749)help
Term ID: 4749
Name: Atrial flutter
Synonym:
Definition: A type of atrial arrhythmia characterized by atrial rates of between 240 and 400 beats per minute and some degree of atrioventricular node conduction block. Typically, the ventricular rate is half the atrial rate. In the EKG; atrial flutter waves are observed as sawtooth-like atrial activity. Pathophysiologically, atrial flutter is a form of atrial reentry in which there is a premature electrical impulse creates a self-propagating circuit.
Comments:
Reference: HP:0004749
Genes and Diseases:
 
       Child Nodes:
........expandTypical atrial flutter (HP:0031671) help
........expandReverse typical atrial flutter (HP:0031672) help

 Sister Nodes: 
..expandAtrial fibrillation (HP:0005110) help
..expandAtrial reentry tachycardia (HP:0011699) help
..expandAutomatic atrial tachycardia (HP:0011700) help
..expandChaotic multifocal atrial tachycardia (HP:0011725) help
..expandMultifocal atrial tachycardia (HP:0011701) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0004749HP:0004749Atrial flutter0ACTC1 CL E G H70143ORPHA:99103Atrial septal defect, ostium secundum typeHP:0040283 - Occasional208
HP:0004749HP:0004749Atrial flutter0ACTC1 CL E G H70143OMIM:612098Cardiomyopathy, familial hypertrophic, 11208
HP:0004749HP:0004749Atrial flutter0CITED2 CL E G H103701987ORPHA:99103Atrial septal defect, ostium secundum typeHP:0040283 - Occasional5
HP:0004749HP:0004749Atrial flutter0CITED2 CL E G H103701987ORPHA:99105Atrial septal defect, sinus venosus typeHP:0040283 - Occasional5
HP:0004749HP:0004749Atrial flutter0CLIC2 CL E G H11932063ORPHA:324410X-linked intellectual disability-cardiomegaly-congestive heart failure syndromeHP:0040283 - Occasional4
HP:0004749HP:0004749Atrial flutter0CYTB CL E G H45197427ORPHA:137675Histiocytoid cardiomyopathyHP:0040284 - Very rare
HP:0004749HP:0004749Atrial flutter0DMPK CL E G H17602933OMIM:160900Myotonic dystrophy 1152
HP:0004749HP:0004749Atrial flutter0GATA4 CL E G H26264173ORPHA:99103Atrial septal defect, ostium secundum typeHP:0040283 - Occasional87
HP:0004749HP:0004749Atrial flutter0GATA6 CL E G H26274174ORPHA:99103Atrial septal defect, ostium secundum typeHP:0040283 - Occasional37
HP:0004749HP:0004749Atrial flutter0KCNK3 CL E G H37776278OMIM:615344Pulmonary hypertension, primary, 47
HP:0004749HP:0004749Atrial flutter0LMNA CL E G H40006636OMIM:115200Cardiomyopathy, dilated, 1A.645
HP:0004749HP:0004749Atrial flutter0LMNA CL E G H40006636ORPHA:300751Familial dilated cardiomyopathy with conduction defect due to LMNA mutationHP:0040283 - Occasional645
HP:0004749HP:0004749Atrial flutter0MYH6 CL E G H46247576ORPHA:99103Atrial septal defect, ostium secundum typeHP:0040283 - Occasional452
HP:0004749HP:0004749Atrial flutter0NKX2-5 CL E G H14822488ORPHA:99103Atrial septal defect, ostium secundum typeHP:0040283 - Occasional90
HP:0004749HP:0004749Atrial flutter0NUP155 CL E G H96318063OMIM:615770Atrial fibrillation, familial, 15.1
HP:0004749HP:0004749Atrial flutter0PRKAG2 CL E G H514229386OMIM:194200WOLFF-PARKINSON-WHITE SYNDROME235
HP:0004749HP:0004749Atrial flutter0SCN3B CL E G H5580020665OMIM:613120Brugada syndrome 7.122
HP:0004749HP:0004749Atrial flutter0SCN5A CL E G H633110593OMIM:614022Atrial fibrillation, familial, 10HP:0040283 - Occasional1134
HP:0004749HP:0004749Atrial flutter0SCN5A CL E G H633110593OMIM:601144BRUGADA SYNDROME 1; BRGDA11134
HP:0004749HP:0004749Atrial flutter0SCN5A CL E G H633110593OMIM:601154Cardiomyopathy, dilated, 1E.1134
HP:0004749HP:0004749Atrial flutter0SGO1 CL E G H15164825088OMIM:616201Chronic atrial and intestinal dysrhythmiaHP:0040283 - Occasional2
HP:0004749HP:0004749Atrial flutter0TBX20 CL E G H5705711598ORPHA:99103Atrial septal defect, ostium secundum typeHP:0040283 - Occasional20
HP:0004749HP:0004749Atrial flutter0TLL1 CL E G H709211843ORPHA:99106Atrial septal defect, ostium primum typeHP:0040283 - Occasional6
HP:0004749HP:0004749Atrial flutter0TLL1 CL E G H709211843ORPHA:99103Atrial septal defect, ostium secundum typeHP:0040283 - Occasional6
HP:0004749HP:0004749Atrial flutter0TNNI3K CL E G H5108619661OMIM:616117Cardiac conduction disease with or without dilated cardiomyopathy.1
HP:0004749HP:0031672Reverse typical atrial flutter1 CL E G H
HP:0004749HP:0031671Typical atrial flutter1 CL E G H


Genes (19) :ACTC1 CITED2 CLIC2 CYTB DMPK GATA4 GATA6 KCNK3 LMNA MYH6 NKX2-5 NUP155 PRKAG2 SCN3B SCN5A SGO1 TBX20 TLL1 TNNI3K

Diseases (18) :ORPHA:99103 OMIM:612098 ORPHA:99105 ORPHA:324410 ORPHA:137675 OMIM:160900 OMIM:615344 OMIM:115200 ORPHA:300751 OMIM:615770 OMIM:194200 OMIM:613120 OMIM:614022 OMIM:601144 OMIM:601154 OMIM:616201 ORPHA:99106 OMIM:616117
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.