Human Phenotype Ontology 
Grandparent Node:
expandDecreased circulating antibody level (HP:0004313)help
Parent Node:
expandDecreased circulating IgA level (HP:0002720)help
..Starting node
..expandSecretory IgA deficiency (HP:0004433)help
Term ID: 4433
Name: Secretory IgA deficiency
Synonym:
Definition: Deficiency of secretory IgA (polymers of 2-4 IgA monomers are linked by two additional chains) and is the primary antibody response at the mucosal level, where it forms immune complexes with pathogens and allergens.
Comments:
Reference: HP:0004433
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandDecreased circulating total IgA (HP:0003460) help
..expandPartial IgA deficiency (HP:0011837) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0004433HP:0004433Secretory IgA deficiency0SON CL E G H665111183ORPHA:500150Brain malformations-musculoskeletal abnormalities-facial dysmorphism-intellectual disability syndromeHP:0040283 - Occasional12


Genes (1) :SON

Diseases (1) :ORPHA:500150
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.