Human Phenotype Ontology 
Grandparent Node:
expand
Abnormality of the vertebral column (HP:0000925)help
Grandparent Node:
expand
Pain (HP:0012531)help
Parent Node:
expand
Back pain (HP:0003418)help
..Starting node
..expand
Low back pain (HP:0003419)help
Term ID: 3419
Name: Low back pain
Synonym: Lower back pain
Definition: An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the lower back.
Comments:
Reference: HP:0003419
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandSciatica (HP:0011868) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0003419HP:0003419Low back pain0ALDH18A1 CL E G H58329722ORPHA:447753Autosomal dominant spastic paraplegia type 9AHP:0040283 - Occasional89
HP:0003419HP:0003419Low back pain0ANXA11 CL E G H311535OMIM:619733INCLUSION BODY MYOPATHY AND BRAIN WHITE MATTER ABNORMALITIES; IBMWMA
HP:0003419HP:0003419Low back pain0COL2A1 CL E G H12802200ORPHA:166011Multiple epiphyseal dysplasia, Beighton typeHP:0040283 - Occasional284
HP:0003419HP:0003419Low back pain0FAR1 CL E G H8418826222ORPHA:447753Autosomal dominant spastic paraplegia type 9AHP:0040283 - Occasional7
HP:0003419HP:0003419Low back pain0HGD CL E G H30814892OMIM:203500Alkaptonuria77
HP:0003419HP:0003419Low back pain0HTRA1 CL E G H56549476OMIM:600142Autosomal recessive cerebral arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL).34
HP:0003419HP:0003419Low back pain0NAB2 CL E G H46657627ORPHA:2126Solitary fibrous tumor/hemangiopericytomaHP:0040284 - Very rare
HP:0003419HP:0003419Low back pain0SPAST CL E G H668311233OMIM:182601Spastic paraplegia 4, autosomal dominant.208
HP:0003419HP:0003419Low back pain0STAT6 CL E G H677811368ORPHA:2126Solitary fibrous tumor/hemangiopericytomaHP:0040284 - Very rare1
HP:0003419HP:0003419Low back pain0TBX6 CL E G H691111605OMIM:122600Spondylocostal dysostosis 5.19
HP:0003419HP:0003419Low back pain0WRN CL E G H748612791OMIM:277700Werner syndrome310


Genes (11) :ALDH18A1 ANXA11 COL2A1 FAR1 HGD HTRA1 NAB2 SPAST STAT6 TBX6 WRN

Diseases (9) :ORPHA:447753 OMIM:619733 ORPHA:166011 OMIM:203500 OMIM:600142 ORPHA:2126 OMIM:182601 OMIM:122600 OMIM:277700
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.