Human Phenotype Ontology 
Grandparent Node:
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Muscle weakness (HP:0001324)help
Parent Node:
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Distal muscle weakness (HP:0002460)help
..Starting node
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First dorsal interossei muscle weakness (HP:0003392)help
Term ID: 3392
Name: First dorsal interossei muscle weakness
Synonym:
Definition:
Comments:
Reference: HP:0003392
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandDistal lower limb muscle weakness (HP:0009053) help
..expandDistal upper limb muscle weakness (HP:0008959) help
..expandLate-onset distal muscle weakness (HP:0003810) help
..expandParesis of extensor muscles of the big toe (HP:0002601) help
..expandProgressive distal muscle weakness (HP:0009063) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0003392HP:0003392First dorsal interossei muscle weakness0ATP1A2 CL E G H477800ORPHA:569Familial or sporadic hemiplegic migraineHP:0040284 - Very rare239
HP:0003392HP:0003392First dorsal interossei muscle weakness0BSCL2 CL E G H2658015832ORPHA:139536Distal hereditary motor neuropathy type 5HP:0040282 - Frequent105
HP:0003392HP:0003392First dorsal interossei muscle weakness0BSCL2 CL E G H2658015832OMIM:270685Spastic paraplegia 17.105
HP:0003392HP:0003392First dorsal interossei muscle weakness0CACNA1A CL E G H7731388ORPHA:569Familial or sporadic hemiplegic migraineHP:0040284 - Very rare449
HP:0003392HP:0003392First dorsal interossei muscle weakness0GARS1 CL E G H26174162OMIM:601472Charcot-Marie-Tooth disease, axonal, type 2D.
HP:0003392HP:0003392First dorsal interossei muscle weakness0GARS1 CL E G H26174162ORPHA:139536Distal hereditary motor neuropathy type 5HP:0040282 - Frequent
HP:0003392HP:0003392First dorsal interossei muscle weakness0GARS1 CL E G H26174162OMIM:600794Neuronopathy, distal hereditary motor, type VA.
HP:0003392HP:0003392First dorsal interossei muscle weakness0JAG1 CL E G H1826188OMIM:619574CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2HH; CMT2HH257
HP:0003392HP:0003392First dorsal interossei muscle weakness0PRRT2 CL E G H11247630500ORPHA:569Familial or sporadic hemiplegic migraineHP:0040284 - Very rare94
HP:0003392HP:0003392First dorsal interossei muscle weakness0REEP1 CL E G H6505525786ORPHA:139536Distal hereditary motor neuropathy type 5HP:0040282 - Frequent87
HP:0003392HP:0003392First dorsal interossei muscle weakness0SCN1A CL E G H632310585ORPHA:569Familial or sporadic hemiplegic migraineHP:0040284 - Very rare1053


Genes (8) :ATP1A2 BSCL2 CACNA1A GARS1 JAG1 PRRT2 REEP1 SCN1A

Diseases (6) :ORPHA:569 ORPHA:139536 OMIM:270685 OMIM:601472 OMIM:600794 OMIM:619574
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.