Human Phenotype Ontology 
Grandparent Node:
expandAbnormality of metabolism/homeostasis (HP:0001939)help
Parent Node:
expandAbnormal circulating protein concentration (HP:0010876)help
..Starting node
..expandAbnormal hepcidin level (HP:0031875)help
Term ID: 31875
Name: Abnormal hepcidin level
Synonym:
Definition: Any deviation from the normal concentration of hepcidin in the blood circulation.
Comments:
Reference: HP:0031875
Genes and Diseases:
 
       Child Nodes:
........expandDecreased hepcidin level (HP:0031876) help
........expandElevated hepcidin level (HP:0031877) help

 Sister Nodes: 
..expandAbnormal B-type natriuretic peptide level (HP:0031138) help
..expandAbnormal circulating albumin concentration (HP:0012116) help
..expandAbnormal circulating apolipoprotein concentration (HP:0025201) help
..expandAbnormal circulating beta globulin level (HP:0025465) help
..expandAbnormal circulating beta-C-terminal telopeptide concentration (HP:0031424) help
..expandAbnormal circulating thyroglobulin level (HP:0025483) help
..expandAbnormal insulin like growth factor binding protein acid labile subunit level (HP:0031034) help
..expandAbnormal levels of alpha-fetoprotein (HP:0045056) help
..expandAbnormal retinol-binding protein level (HP:0031031) help
..expandAbnormality of circulating enzyme level (HP:0011021) help
..expandAbnormality of the kinin-kallikrein system (HP:0005559) help
..expandDecreased prealbumin level (HP:0031085) help
..expandElevated carcinoembryonic antigen level (HP:0031029) help
..expandElevated carcinoma antigen 125 level (HP:0031030) help
..expandElevated circulating C-reactive protein concentration (HP:0011227) help
..expandElevated prostate-specific antigen level (HP:0025020) help
..expandHyperpepsinogenemia I (HP:0003238) help
..expandHyperproteinemia (HP:0002152) help
..expandHypoproteinemia (HP:0003075) help
..expandIncreased circulating thyroxine-binding globulin level (HP:0031222) help
..expandReduced growth-hormone binding protein level (HP:0031036) help
..expandReduced insulin-like factor 3 level (HP:0031037) help
..expandReduced sex -hormone binding protein level (HP:0031419) help
..expandReduced thyroxin-binding globulin (HP:0012509) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0031875HP:0031875Abnormal hepcidin level0TMPRSS6 CL E G H16465616517OMIM:206200IRON-REFRACTORY IRON DEFICIENCY ANEMIA; IRIDA65
HP:0031875HP:0031876Decreased hepcidin level1 CL E G H
HP:0031875HP:0031877Elevated hepcidin level1TMPRSS6 CL E G H16465616517OMIM:206200IRON-REFRACTORY IRON DEFICIENCY ANEMIA; IRIDA65


Genes (1) :TMPRSS6

Diseases (1) :OMIM:206200
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.