Human Phenotype Ontology 
Grandparent Node:
expandAbnormal oral cavity morphology (HP:0000163)help
Parent Node:
expandAbnormal lip morphology (HP:0000159)help
..Starting node
..expandLip fissure (HP:0031250)help
Term ID: 31250
Name: Lip fissure
Synonym:
Definition: A severe crack in a lip. A lip fissure may be painful, may bleed and often is a recurring manifestation.
Comments:
Reference: HP:0031250
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAbnormal lower lip morphology (HP:0000178) help
..expandAbnormal upper lip morphology (HP:0000177) help
..expandChapped lip (HP:0040181) help
..expandCheilitis (HP:0100825) help
..expandEclabion (HP:0012472) help
..expandFused lips (HP:0100788) help
..expandLip discoloration (HP:0025118) help
..expandLip freckle (HP:0010798) help
..expandLip hyperpigmentation (HP:0100816) help
..expandLip pit (HP:0100267) help
..expandLip telangiectasia (HP:0000214) help
..expandNeoplasm of the lip (HP:0100604) help
..expandSwollen lip (HP:0031244) help
..expandThick vermilion border (HP:0012471) help
..expandThin vermilion border (HP:0000233) help
..expandVascular malformation of the lip (HP:0031486) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0031250HP:0031250Lip fissure0GJB2 CL E G H27064284ORPHA:477KID syndrome199
HP:0031250HP:0031250Lip fissure0GJB6 CL E G H108044288ORPHA:477KID syndrome56


Genes (2) :GJB2 GJB6

Diseases (1) :ORPHA:477
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.