Human Phenotype Ontology 
Grandparent Node:
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Abnormality of the endocrine system (HP:0000818)help
Parent Node:
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Abnormal endocrine physiology (HP:0031072)help
..Starting node
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Inappropriate antidiuretic hormone secretion (HP:0031218)help
Term ID: 31218
Name: Inappropriate antidiuretic hormone secretion
Synonym: Inappropriate ADH secretion; SIADH; Syndrome of inappropriate antidiuretic hormone secretion
Definition: A state of increased circulating antidiuretic hormone despite hyponatremia and hypo-osmolality with normal or increased plasma volume.
Comments:
Reference: HP:0031218
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAbnormal response to endocrine stimulation test (HP:0031073) help
..expandAbnormal response to glucagon stimulation test (HP:0031080) help
..expandAbnormal response to human chorionic gonadotrophin stimulation test (HP:0031083) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0031218HP:0031218Inappropriate antidiuretic hormone secretion0HESX1 CL E G H88204877ORPHA:226307Hypothyroidism due to deficient transcription factors involved in pituitary development or functionHP:0040283 - Occasional21
HP:0031218HP:0031218Inappropriate antidiuretic hormone secretion0LHX3 CL E G H80226595ORPHA:226307Hypothyroidism due to deficient transcription factors involved in pituitary development or functionHP:0040283 - Occasional51
HP:0031218HP:0031218Inappropriate antidiuretic hormone secretion0LHX4 CL E G H8988421734ORPHA:226307Hypothyroidism due to deficient transcription factors involved in pituitary development or functionHP:0040283 - Occasional43
HP:0031218HP:0031218Inappropriate antidiuretic hormone secretion0MOGS CL E G H784124862ORPHA:79330MOGS-CDGHP:0040283 - Occasional37
HP:0031218HP:0031218Inappropriate antidiuretic hormone secretion0POU1F1 CL E G H54499210ORPHA:226307Hypothyroidism due to deficient transcription factors involved in pituitary development or functionHP:0040283 - Occasional36
HP:0031218HP:0031218Inappropriate antidiuretic hormone secretion0PPOX CL E G H54989280ORPHA:79473Porphyria variegataHP:0040283 - Occasional41
HP:0031218HP:0031218Inappropriate antidiuretic hormone secretion0PROP1 CL E G H56269455ORPHA:226307Hypothyroidism due to deficient transcription factors involved in pituitary development or functionHP:0040283 - Occasional54
HP:0031218HP:0031218Inappropriate antidiuretic hormone secretion0SP110 CL E G H34315401ORPHA:79124Hepatic veno-occlusive disease-immunodeficiency syndromeHP:0040283 - Occasional49


Genes (8) :HESX1 LHX3 LHX4 MOGS POU1F1 PPOX PROP1 SP110

Diseases (4) :ORPHA:226307 ORPHA:79330 ORPHA:79473 ORPHA:79124
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.