Human Phenotype Ontology 
Grandparent Node:
expand
Phenotypic abnormality (HP:0000118)help
Parent Node:
expand
Abnormality of prenatal development or birth (HP:0001197)help
..Starting node
..expand
Twin-to-twin transfusion (HP:0031110)help
Term ID: 31110
Name: Twin-to-twin transfusion
Synonym: Twin to twin transfusion syndrome
Definition: As a result of sharing a single placenta, the blood supplies of monochorionic twin fetuses can become connected, so that they share blood circulation: although each fetus uses its own portion of the placenta, the connecting blood vessels within the placenta allow blood to pass from one twin to the other.Depending on the number, type and direction of the interconnecting blood vessels (anastomoses), blood can be transferred disproportionately from one twin (the donor) to the other (the recipient). This state of transfusion causes the donor twin to have decreased blood volume, retarding the donor's development and growth. The blood volume of the recipient twin is increased, which can strain the fetus's heart and eventually lead to heart failure.
Comments:
Reference: HP:0031110
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAbnormal delivery (HP:0001787) help
..expandAbnormalities of placenta or umbilical cord (HP:0001194) help
..expandAbnormality of the amniotic fluid (HP:0001560) help
..expandFemale fetal virilization (HP:0031170) help
..expandFetal ascites (HP:0001791) help
..expandFetal distress (HP:0025116) help
..expandFetal ultrasound soft marker (HP:0011425) help
..expandHydrops fetalis (HP:0001789) help
..expandIncreased nuchal translucency (HP:0010880) help
..expandIntrauterine fetal demise of one twin after midgestation (HP:0030753) help
..expandLow APGAR score (HP:0030917) help
..expandPostterm pregnancy (HP:0031169) help
..expandPremature birth (HP:0001622) help
..expandPrenatal maternal abnormality (HP:0002686) help
..expandPrenatal movement abnormality (HP:0001557) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0031110HP:0031110Twin-to-twin transfusion0 CL E G H


Genes (0) :

Diseases (0) :
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.