Human Phenotype Ontology 
Grandparent Node:
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Abnormality of movement (HP:0100022)help
Parent Node:
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Primitive reflex (HP:0002476)help
..Starting node
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Grasp reflex (HP:0030903)help
Term ID: 30903
Name: Grasp reflex
Synonym: Palmar grasp reflex
Definition: A type of primitive reflex that can be elicated when the hand of the examiner is gently inserted into the palm of the patient's hand. The palmar surface is stroked or simply touched. The flexor surfaces of the fingers may be stimulated also by the examiner's fingers. The stimulus should be in a distal direction. With a positive response, the patient grasps the examiner's hand with variable strength and continues to grasp as the examiner's hand is moved. Ability to release the grip voluntarily depends on the activity of the reflex; some patients can do so readily, while others can even be lifted off the bed, since the grasp has such power [NCBI Books:NBK395].
Comments:
Reference: HP:0030903
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandGlabellar reflex (HP:0030904) help
..expandPalmomental reflex (HP:0030902) help
..expandSnout reflex (HP:0030905) help
..expandSuck reflex (HP:0030906) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0030903HP:0030903Grasp reflex0AARS1 CL E G H1620OMIM:619661LEUKOENCEPHALOPATHY, HEREDITARY DIFFUSE, WITH SPHEROIDS 2; HDLS2
HP:0030903HP:0030903Grasp reflex0PIGA CL E G H52778957OMIM:301072NEURODEVELOPMENTAL DISORDER WITH EPILEPSY AND HEMOCHROMATOSIS; NEDEPH46
HP:0030903HP:0030903Grasp reflex0TUBB3 CL E G H1038120772ORPHA:300570Cortical dysgenesis with pontocerebellar hypoplasia due to TUBB3 mutationHP:0040283 - Occasional64


Genes (3) :AARS1 PIGA TUBB3

Diseases (3) :OMIM:619661 OMIM:301072 ORPHA:300570
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.