Human Phenotype Ontology 
Grandparent Node:
expand
Abnormality of the lymphatic system (HP:0100763)help
Parent Node:
expand
Abnormality of the lymph nodes (HP:0002733)help
..Starting node
..expand
Absence of lymph node germinal center (HP:0002849)help
Term ID: 2849
Name: Absence of lymph node germinal center
Synonym: Absence of lymph node germinal centre; Lymph nodes lack germinal center; Lymph nodes lack germinal centre; Lymphoid germinal center defect; Lymphoid germinal centre defect
Definition: Absence of germinal centers in lymph nodes. Germinal centers are the parts of lymph nodes in which B lymphocytes proliferate, differentiate, mutate through somatic hypermutation and class switch during antibody responses.
Comments:
Reference: HP:0002849
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAbnormality of mesenteric lymph nodes (HP:0025042) help
..expandLymph node hypoplasia (HP:0002732) help
..expandLymphadenitis (HP:0002840) help
..expandLymphadenopathy (HP:0002716) help


Genes (6) :ADA CD40 CD40LG EPHB4 PTPRC SP110

Diseases (7) :ORPHA:277 OMIM:606843 OMIM:308230 ORPHA:90186 OMIM:619924 ORPHA:79124 OMIM:235550
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.