Human Phenotype Ontology 
Grandparent Node:
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Abnormal inflammatory response (HP:0012647)help
Parent Node:
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Abnormality of the lymph nodes (HP:0002733)help
Parent Node:
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Increased inflammatory response (HP:0012649)help
..Starting node
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Lymphadenitis (HP:0002840)help
Term ID: 2840
Name: Lymphadenitis
Synonym: Inflammation of the lymph nodes
Definition: Inflammation of a lymph node.
Comments:
Reference: HP:0002840
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandCholangitis (HP:0030151) help
..expandChondritis (HP:0100662) help
..expandEndocarditis (HP:0100584) help
..expandEpididymitis (HP:0000031) help
..expandFasciitis (HP:0100537) help
..expandGastrointestinal inflammation (HP:0004386) help
..expandHepatitis (HP:0012115) help
..expandInflammatory abnormality of the eye (HP:0100533) help
..expandInflammatory abnormality of the skin (HP:0011123) help
..expandMeningitis (HP:0001287) help
..expandMyelitis (HP:0012486) help
..expandMyositis (HP:0100614) help
..expandNephritis (HP:0000123) help
..expandOptic neuritis (HP:0100653) help
..expandOsteomyelitis (HP:0002754) help
..expandOtitis media (HP:0000388) help
..expandPancreatitis (HP:0001733) help
..expandPanniculitis (HP:0012490) help
..expandPeriodontitis (HP:0000704) help
..expandPneumonia (HP:0002090) help
..expandProstatitis (HP:0000024) help
..expandSerositis (HP:0045073) help
..expandSinusitis (HP:0000246) help
..expandStomatitis (HP:0010280) help
..expandThyroiditis (HP:0100646) help
..expandUrinary bladder inflammation (HP:0100577) help
..expandVaginitis (HP:0030683) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0002840HP:0002840Lymphadenitis0CXCR4 CL E G H78522561ORPHA:51636WHIM syndromeHP:0040284 - Very rare9
HP:0002840HP:0002840Lymphadenitis0CYBA CL E G H15352577OMIM:233690GRANULOMATOUS DISEASE, CHRONIC, AUTOSOMAL RECESSIVE, CYTOCHROME b-NEGATIVE.27
HP:0002840HP:0002840Lymphadenitis0CYBB CL E G H15362578OMIM:306400Chronic granulomatous disease, X-linked.111
HP:0002840HP:0002840Lymphadenitis0CYBC1 CL E G H7941528672OMIM:618935GRANULOMATOUS DISEASE, CHRONIC, AUTOSOMAL RECESSIVE, 5; CGD5
HP:0002840HP:0002840Lymphadenitis0IL12RB1 CL E G H35945971ORPHA:319552Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiencyHP:0040282 - Frequent46
HP:0002840HP:0002840Lymphadenitis0IRF8 CL E G H33945358OMIM:614893IMMUNODEFICIENCY 32A; IMD32A5
HP:0002840HP:0002840Lymphadenitis0MVK CL E G H45987530OMIM:260920Hyper-Igd syndrome150
HP:0002840HP:0002840Lymphadenitis0MYD88 CL E G H46157562OMIM:612260MYD88 DEFICIENCY; MYD88D9
HP:0002840HP:0002840Lymphadenitis0NCF1 CL E G H6533617660OMIM:233700Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type I.13
HP:0002840HP:0002840Lymphadenitis0NCF2 CL E G H46887661OMIM:233710Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type II.67
HP:0002840HP:0002840Lymphadenitis0RAC2 CL E G H58809802OMIM:618986IMMUNODEFICIENCY 73B WITH DEFECTIVE NEUTROPHIL CHEMOTAXIS AND LYMPHOPENIA; IMD73B9
HP:0002840HP:0002840Lymphadenitis0RAG1 CL E G H58969831ORPHA:331206Severe combined immunodeficiency due to complete RAG1/2 deficiencyHP:0040283 - Occasional127
HP:0002840HP:0002840Lymphadenitis0RAG2 CL E G H58979832ORPHA:331206Severe combined immunodeficiency due to complete RAG1/2 deficiencyHP:0040283 - Occasional50
HP:0002840HP:0002840Lymphadenitis0RBCK1 CL E G H1061615864OMIM:615895Polyglucosan body myopathy 1 with or without immunodeficiency10
HP:0002840HP:0002840Lymphadenitis0STAT2 CL E G H677311363OMIM:618886PSEUDO-TORCH SYNDROME 3; PTORCH39
HP:0002840HP:0002840Lymphadenitis0ZAP70 CL E G H753512858ORPHA:911Combined immunodeficiency due to ZAP70 deficiencyHP:0040283 - Occasional46


Genes (16) :CXCR4 CYBA CYBB CYBC1 IL12RB1 IRF8 MVK MYD88 NCF1 NCF2 RAC2 RAG1 RAG2 RBCK1 STAT2 ZAP70

Diseases (15) :ORPHA:51636 OMIM:233690 OMIM:306400 OMIM:618935 ORPHA:319552 OMIM:614893 OMIM:260920 OMIM:612260 OMIM:233700 OMIM:233710 OMIM:618986 ORPHA:331206 OMIM:615895 OMIM:618886 ORPHA:911
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.