Term ID: |
2840 |
Name: |
Lymphadenitis |
Synonym: |
Inflammation of the lymph nodes |
Definition: |
Inflammation of a lymph node. |
Comments: |
|
Reference: |
HP:0002840 |
Genes and Diseases: | |
Child Nodes: |
Sister Nodes: |
..Cholangitis (HP:0030151)
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..Chondritis (HP:0100662)
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..Endocarditis (HP:0100584)
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..Epididymitis (HP:0000031)
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..Fasciitis (HP:0100537)
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..Gastrointestinal inflammation (HP:0004386)
|
..Hepatitis (HP:0012115)
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..Inflammatory abnormality of the eye (HP:0100533)
|
..Inflammatory abnormality of the skin (HP:0011123)
|
..Meningitis (HP:0001287)
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..Myelitis (HP:0012486)
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..Myositis (HP:0100614)
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..Nephritis (HP:0000123)
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..Optic neuritis (HP:0100653)
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..Osteomyelitis (HP:0002754)
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..Otitis media (HP:0000388)
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..Pancreatitis (HP:0001733)
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..Panniculitis (HP:0012490)
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..Periodontitis (HP:0000704)
|
..Pneumonia (HP:0002090)
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..Prostatitis (HP:0000024)
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..Serositis (HP:0045073)
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..Sinusitis (HP:0000246)
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..Stomatitis (HP:0010280)
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..Thyroiditis (HP:0100646)
|
..Urinary bladder inflammation (HP:0100577)
|
..Vaginitis (HP:0030683)
|
Input | HPO ID | HPO term | Distance | Gene | Gene id entrez | HGNC ID | DiseaseId | DiseaseName | Frequency | Onset | HGMD variants | ClinVar variants |
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HPO disease - gene - phenotype typical associations: | HPO disease - gene - phenotype less frequent non-typical associations: | HP:0002840 | HP:0002840 | Lymphadenitis | 0 | CXCR4 CL E G H | 7852 | 2561 | ORPHA:51636 | WHIM syndrome | HP:0040284 - Very rare | | | 9 | | | HP:0002840 | HP:0002840 | Lymphadenitis | 0 | CYBA CL E G H | 1535 | 2577 | OMIM:233690 | GRANULOMATOUS DISEASE, CHRONIC, AUTOSOMAL RECESSIVE, CYTOCHROME b-NEGATIVE | . | | | 27 | | | HP:0002840 | HP:0002840 | Lymphadenitis | 0 | CYBB CL E G H | 1536 | 2578 | OMIM:306400 | Chronic granulomatous disease, X-linked | . | | | 111 | | | HP:0002840 | HP:0002840 | Lymphadenitis | 0 | CYBC1 CL E G H | 79415 | 28672 | OMIM:618935 | GRANULOMATOUS DISEASE, CHRONIC, AUTOSOMAL RECESSIVE, 5; CGD5 | | | | | | | HP:0002840 | HP:0002840 | Lymphadenitis | 0 | IL12RB1 CL E G H | 3594 | 5971 | ORPHA:319552 | Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiency | HP:0040282 - Frequent | | | 46 | | | HP:0002840 | HP:0002840 | Lymphadenitis | 0 | IRF8 CL E G H | 3394 | 5358 | OMIM:614893 | IMMUNODEFICIENCY 32A; IMD32A | | | | 5 | | | HP:0002840 | HP:0002840 | Lymphadenitis | 0 | MVK CL E G H | 4598 | 7530 | OMIM:260920 | Hyper-Igd syndrome | | | | 150 | | | HP:0002840 | HP:0002840 | Lymphadenitis | 0 | MYD88 CL E G H | 4615 | 7562 | OMIM:612260 | MYD88 DEFICIENCY; MYD88D | | | | 9 | | | HP:0002840 | HP:0002840 | Lymphadenitis | 0 | NCF1 CL E G H | 653361 | 7660 | OMIM:233700 | Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type I | . | | | 13 | | | HP:0002840 | HP:0002840 | Lymphadenitis | 0 | NCF2 CL E G H | 4688 | 7661 | OMIM:233710 | Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type II | . | | | 67 | | | HP:0002840 | HP:0002840 | Lymphadenitis | 0 | RAC2 CL E G H | 5880 | 9802 | OMIM:618986 | IMMUNODEFICIENCY 73B WITH DEFECTIVE NEUTROPHIL CHEMOTAXIS AND LYMPHOPENIA; IMD73B | | | | 9 | | | HP:0002840 | HP:0002840 | Lymphadenitis | 0 | RAG1 CL E G H | 5896 | 9831 | ORPHA:331206 | Severe combined immunodeficiency due to complete RAG1/2 deficiency | HP:0040283 - Occasional | | | 127 | | | HP:0002840 | HP:0002840 | Lymphadenitis | 0 | RAG2 CL E G H | 5897 | 9832 | ORPHA:331206 | Severe combined immunodeficiency due to complete RAG1/2 deficiency | HP:0040283 - Occasional | | | 50 | | | HP:0002840 | HP:0002840 | Lymphadenitis | 0 | RBCK1 CL E G H | 10616 | 15864 | OMIM:615895 | Polyglucosan body myopathy 1 with or without immunodeficiency | | | | 10 | | | HP:0002840 | HP:0002840 | Lymphadenitis | 0 | STAT2 CL E G H | 6773 | 11363 | OMIM:618886 | PSEUDO-TORCH SYNDROME 3; PTORCH3 | | | | 9 | | | HP:0002840 | HP:0002840 | Lymphadenitis | 0 | ZAP70 CL E G H | 7535 | 12858 | ORPHA:911 | Combined immunodeficiency due to ZAP70 deficiency | HP:0040283 - Occasional | | | 46 | | |
Genes (16) :CXCR4 CYBA CYBB CYBC1 IL12RB1 IRF8 MVK MYD88 NCF1 NCF2 RAC2 RAG1 RAG2 RBCK1 STAT2 ZAP70
Diseases (15) :ORPHA:51636 OMIM:233690 OMIM:306400 OMIM:618935 ORPHA:319552 OMIM:614893 OMIM:260920 OMIM:612260 OMIM:233700 OMIM:233710 OMIM:618986 ORPHA:331206 OMIM:615895 OMIM:618886 ORPHA:911 |
Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.
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