Human Phenotype Ontology 
Grandparent Node:
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Abnormal testis morphology (HP:0000035)help
Grandparent Node:
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Gonadal neoplasm (HP:0010785)help
Grandparent Node:
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Neoplasm of the male external genitalia (HP:0100848)help
Parent Node:
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Testicular neoplasm (HP:0010788)help
..Starting node
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Testicular adrenal rest tumor (HP:0025451)help
Term ID: 25451
Name: Testicular adrenal rest tumor
Synonym: Testicular adrenal rest tumour
Definition: Testicular adrenal rest tumor (TART) is a abenign tumor of the testis. TART generally occurs multiply and bilaterally within the rete testis. Histologically, TART resemble adrenocortical tissue, which led to the name. The tumous are not encapsulated and consist of sheets or confluent cords of large polygonal cells with abundant eosinophilic cytoplasm.
Comments:
Reference: HP:0025451
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandLeydig cell neoplasia (HP:0100618) help
..expandSertoli cell neoplasm (HP:0100619) help
..expandTesticular gonadoblastoma (HP:0000030) help
..expandTesticular mesothelioma (HP:0100005) help
..expandTesticular seminoma (HP:0100617) help
..expandTesticular teratoma (HP:0100616) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0025451HP:0025451Testicular adrenal rest tumor0CYP11B1 CL E G H15842591ORPHA:90795Congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiencyHP:0040283 - Occasional112
HP:0025451HP:0025451Testicular adrenal rest tumor0MC2R CL E G H41586930ORPHA:361Familial glucocorticoid deficiencyHP:0040283 - Occasional94
HP:0025451HP:0025451Testicular adrenal rest tumor0MRAP CL E G H562461304ORPHA:361Familial glucocorticoid deficiencyHP:0040283 - Occasional26
HP:0025451HP:0025451Testicular adrenal rest tumor0NNT CL E G H235307863ORPHA:361Familial glucocorticoid deficiencyHP:0040283 - Occasional13
HP:0025451HP:0025451Testicular adrenal rest tumor0PDE11A CL E G H509408773ORPHA:1359Carney complex13
HP:0025451HP:0025451Testicular adrenal rest tumor0PRKAR1A CL E G H55739388ORPHA:1359Carney complex134
HP:0025451HP:0025451Testicular adrenal rest tumor0STAR CL E G H677011359ORPHA:361Familial glucocorticoid deficiencyHP:0040283 - Occasional45
HP:0025451HP:0025451Testicular adrenal rest tumor0TXNRD2 CL E G H1058718155ORPHA:361Familial glucocorticoid deficiencyHP:0040283 - Occasional85


Genes (8) :CYP11B1 MC2R MRAP NNT PDE11A PRKAR1A STAR TXNRD2

Diseases (3) :ORPHA:90795 ORPHA:361 ORPHA:1359
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.