Human Phenotype Ontology 
Grandparent Node:
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Abnormality of the face (HP:0000271)help
Parent Node:
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Abnormality of the periorbital region (HP:0000606)help
..Starting node
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Bitemporal hollowing (HP:0025386)help
Term ID: 25386
Name: Bitemporal hollowing
Synonym:
Definition: Depression of profile in both temporal regions.
Comments:
Reference: HP:0025386
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAbnormal eyebrow morphology (HP:0000534) help
..expandAbnormal morphology of bony orbit of skull (HP:3000030) help
..expandAbnormality of the supraorbital ridges (HP:0100538) help
..expandBitemporal forceps marks (HP:0011336) help
..expandInfra-orbital crease (HP:0100876) help
..expandInfra-orbital fold (HP:0011232) help
..expandOrbital cyst (HP:0001144) help
..expandPeriorbital ecchymosis with tarsal plate sparing (HP:0025553) help
..expandPeriorbital edema (HP:0100539) help
..expandPeriorbital fullness (HP:0000629) help
..expandPeriorbital hyperpigmentation (HP:0001106) help
..expandPeriorbital purpura (HP:0025552) help
..expandPeriorbital wrinkles (HP:0000607) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0025386HP:0025386Bitemporal hollowing0EXOC2 CL E G H5577024968OMIM:619306NEURODEVELOPMENTAL DISORDER WITH DYSMORPHIC FACIES AND CEREBELLAR HYPOPLASIA; NEDFACH1
HP:0025386HP:0025386Bitemporal hollowing0SPTBN1 CL E G H671111275OMIM:619475DEVELOPMENTAL DELAY, IMPAIRED SPEECH, AND BEHAVIORAL ABNORMALITIES; DDISBA


Genes (2) :EXOC2 SPTBN1

Diseases (2) :OMIM:619306 OMIM:619475
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.