Human Phenotype Ontology 
Grandparent Node:
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Abnormality of the skeletal system (HP:0000924)help
Parent Node:
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Abnormal skeletal morphology (HP:0011842)help
..Starting node
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Abnormal growth plate morphology (HP:0025368)help
Term ID: 25368
Name: Abnormal growth plate morphology
Synonym: Abnormality of growth plate morphology
Definition: A structural anomaly of the growth plates (epiphyseal plates), areas of cartilage located near the ends of long bones that are located between the metaphysis (widened part of the shaft of the bone) and the epiphysis (end of the bone) and in which growth occurs in the developing bone. After conclusion of bone growth, the growth plates ossify (harden into solid bone).
Comments:
Reference: HP:0025368
Genes and Diseases:
 
       Child Nodes:
........expandThick growth plates (HP:0025369) help

 Sister Nodes: 
..expandAbnormal appendicular skeleton morphology (HP:0011844) help
..expandAbnormal axial skeleton morphology (HP:0009121) help
..expandAbnormal bone structure (HP:0003330) help
..expandAbnormal cartilage morphology (HP:0002763) help
..expandAbnormal hyoid bone morphology (HP:3000052) help
..expandAbnormal joint morphology (HP:0001367) help
..expandAbnormal mandibular symphysis morphology (HP:3000079) help
..expandAbnormal synovial bursa morphology (HP:0025231) help
..expandAbnormal tendon morphology (HP:0100261) help
..expandAplasia/hypoplasia involving the skeleton (HP:0009115) help
..expandDysostosis multiplex (HP:0000943) help
..expandHyperostosis (HP:0100774) help
..expandHyperplastic callus formation (HP:0030268) help
..expandNeoplasm of the skeletal system (HP:0010622) help
..expandobsolete Abnormality of cartilage morphology (HP:0410007) help
..expandSkeletal dysplasia (HP:0002652) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0025368HP:0025368Abnormal growth plate morphology0COL10A1 CL E G H13002185ORPHA:174Metaphyseal chondrodysplasia, Schmid type79
HP:0025368HP:0025368Abnormal growth plate morphology0MMP13 CL E G H43227159ORPHA:93356Spondyloepimetaphyseal dysplasia, Missouri type52
HP:0025368HP:0025368Abnormal growth plate morphology0PHEX CL E G H52518918ORPHA:89936X-linked hypophosphatemia217
HP:0025368HP:0025369Thick growth plates1COL10A1 CL E G H13002185ORPHA:174Metaphyseal chondrodysplasia, Schmid typeHP:0040281 - Very frequent79
HP:0025368HP:0025369Thick growth plates1MMP13 CL E G H43227159ORPHA:93356Spondyloepimetaphyseal dysplasia, Missouri typeHP:0040282 - Frequent52
HP:0025368HP:0025369Thick growth plates1PHEX CL E G H52518918ORPHA:89936X-linked hypophosphatemiaHP:0040283 - Occasional217


Genes (3) :COL10A1 MMP13 PHEX

Diseases (3) :ORPHA:174 ORPHA:93356 ORPHA:89936
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.