Human Phenotype Ontology

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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Behavioral abnormality (HP:0000708)

Parent Node:
Abnormal temper tantrums (HP:0025160)

..Starting node
..Frequent temper tantrums (HP:0025161)

Term ID:

25161

Name:

Frequent temper tantrums

Synonym:

Definition:

Temper tantrums that occur more frequently than usual.

Comments:

Reference:

HP:0025161

Genes and Diseases:

Child Nodes:

Sister Nodes:

Severe temper tantrums (HP:0025162)

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0025161	HP:0025161	Frequent temper tantrums	0	ARPC4 CL E G H	10093	707	OMIM:620141
HP:0025161	HP:0025161	Frequent temper tantrums	0	CLCN3 CL E G H	1182	2021	OMIM:619512	NEURODEVELOPMENTAL DISORDER WITH HYPOTONIA AND BRAIN ABNORMALITIES; NEDHYBA	2
HP:0025161	HP:0025161	Frequent temper tantrums	0	KAT5 CL E G H	10524	5275	OMIM:619103	NEURODEVELOPMENTAL DISORDER WITH DYSMORPHIC FACIES, SLEEP DISTURBANCE, AND BRAIN ABNORMALITIES; NEDFASB	1
HP:0025161	HP:0025161	Frequent temper tantrums	0	SATB2 CL E G H	23314	21637	OMIM:612313	Glass syndrome	34
HP:0025161	HP:0025161	Frequent temper tantrums	0	SETBP1 CL E G H	26040	15573	OMIM:616078	Mental retardation, autosomal dominant 29	143
HP:0025161	HP:0025161	Frequent temper tantrums	0	TAOK1 CL E G H	57551	29259	OMIM:619575	DEVELOPMENTAL DELAY WITH OR WITHOUT INTELLECTUAL IMPAIRMENT OR BEHAVIORAL ABNORMALITIES; DDIB
HP:0025161	HP:0025161	Frequent temper tantrums	0	TLK2 CL E G H	11011	11842	OMIM:618050	Mental retardation, autosomal dominant 57	1

Genes (7) :ARPC4 CLCN3 KAT5 SATB2 SETBP1 TAOK1 TLK2

Diseases (7) :OMIM:620141 OMIM:619512 OMIM:619103 OMIM:612313 OMIM:616078 OMIM:619575 OMIM:618050

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.

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