Human Phenotype Ontology 
Grandparent Node:
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Phenotypic abnormality (HP:0000118)help
Parent Node:
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Constitutional symptom (HP:0025142)help
..Starting node
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Chills (HP:0025143)help
Term ID: 25143
Name: Chills
Synonym: Chills
Definition: A sudden sensation of feeling cold.
Comments:
Reference: HP:0025143
Genes and Diseases:
 
       Child Nodes:
........expandRigors (HP:0025145) help

 Sister Nodes: 
..expandAsthenia (HP:0025406) help
..expandBody odor (HP:0500001) help
..expandChest tightness (HP:0031352) help
..expandFatigue (HP:0012378) help
..expandHot flashes (HP:0031217) help
..expandImpairment of activities of daily living (HP:0031058) help
..expandNight sweats (HP:0030166) help
..expandPain (HP:0012531) help
..expandShivering (HP:0025144) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0025143HP:0025143Chills0ANK1 CL E G H286492ORPHA:822Hereditary spherocytosisHP:0040283 - Occasional150
HP:0025143HP:0025143Chills0EPB41 CL E G H20353377ORPHA:288Hereditary elliptocytosisHP:0040284 - Very rare6
HP:0025143HP:0025143Chills0EPB42 CL E G H20383381ORPHA:822Hereditary spherocytosisHP:0040283 - Occasional51
HP:0025143HP:0025143Chills0GYPC CL E G H29954704ORPHA:288Hereditary elliptocytosisHP:0040284 - Very rare5
HP:0025143HP:0025143Chills0HADHA CL E G H30304801ORPHA:746Mitochondrial trifunctional protein deficiency99
HP:0025143HP:0025143Chills0HADHB CL E G H30324803ORPHA:746Mitochondrial trifunctional protein deficiency60
HP:0025143HP:0025143Chills0HAVCR2 CL E G H8486818437ORPHA:86884Subcutaneous panniculitis-like T-cell lymphomaHP:0040282 - Frequent
HP:0025143HP:0025143Chills0MVK CL E G H45987530OMIM:260920Hyper-Igd syndrome150
HP:0025143HP:0025143Chills0NLRP3 CL E G H11454816400OMIM:120100FAMILIAL COLD AUTOINFLAMMATORY SYNDROME 1; FCAS1217
HP:0025143HP:0025143Chills0PKHD1 CL E G H53149016ORPHA:53035Caroli diseaseHP:0040283 - Occasional563
HP:0025143HP:0025143Chills0SLC4A1 CL E G H652111027ORPHA:822Hereditary spherocytosisHP:0040283 - Occasional109
HP:0025143HP:0025143Chills0SPTA1 CL E G H670811272ORPHA:288Hereditary elliptocytosisHP:0040284 - Very rare228
HP:0025143HP:0025143Chills0SPTA1 CL E G H670811272ORPHA:822Hereditary spherocytosisHP:0040283 - Occasional228
HP:0025143HP:0025143Chills0SPTB CL E G H671011274ORPHA:288Hereditary elliptocytosisHP:0040284 - Very rare156
HP:0025143HP:0025143Chills0SPTB CL E G H671011274ORPHA:822Hereditary spherocytosisHP:0040283 - Occasional156
HP:0025143HP:0025143Chills0TBK1 CL E G H2911011584ORPHA:1930Herpes simplex virus encephalitisHP:0040283 - Occasional20
HP:0025143HP:0025143Chills0TICAM1 CL E G H14802218348ORPHA:1930Herpes simplex virus encephalitisHP:0040283 - Occasional6
HP:0025143HP:0025143Chills0TLR3 CL E G H709811849ORPHA:1930Herpes simplex virus encephalitisHP:0040283 - Occasional3
HP:0025143HP:0025143Chills0TRAF3 CL E G H718712033ORPHA:1930Herpes simplex virus encephalitisHP:0040283 - Occasional2
HP:0025143HP:0025143Chills0UNC93B1 CL E G H8162213481ORPHA:1930Herpes simplex virus encephalitisHP:0040283 - Occasional5
HP:0025143HP:0025145Rigors1HADHA CL E G H30304801ORPHA:746Mitochondrial trifunctional protein deficiencyHP:0040284 - Very rare99
HP:0025143HP:0025145Rigors1HADHB CL E G H30324803ORPHA:746Mitochondrial trifunctional protein deficiencyHP:0040284 - Very rare60


Genes (18) :ANK1 EPB41 EPB42 GYPC HADHA HADHB HAVCR2 MVK NLRP3 PKHD1 SLC4A1 SPTA1 SPTB TBK1 TICAM1 TLR3 TRAF3 UNC93B1

Diseases (8) :ORPHA:822 ORPHA:288 ORPHA:746 ORPHA:86884 OMIM:260920 OMIM:120100 ORPHA:53035 ORPHA:1930
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.