Human Phenotype Ontology

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	Frequency	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0002360	HP:0002360	Sleep disturbance	0	ABCB11 CL E G H	8647	42	ORPHA:69665	Intrahepatic cholestasis of pregnancy		146
HP:0002360	HP:0002360	Sleep disturbance	0	ABCB4 CL E G H	5244	45	ORPHA:69665	Intrahepatic cholestasis of pregnancy		111
HP:0002360	HP:0002360	Sleep disturbance	0	ABCC9 CL E G H	10060	60	OMIM:619719	INTELLECTUAL DISABILITY AND MYOPATHY SYNDROME; IDMYS		254
HP:0002360	HP:0002360	Sleep disturbance	0	ACAT1 CL E G H	38	93	ORPHA:134	Beta-ketothiolase deficiency		91
HP:0002360	HP:0002360	Sleep disturbance	0	ACTA1 CL E G H	58	129	ORPHA:2020	Congenital fiber-type disproportion myopathy	HP:0040283 - Occasional	96
HP:0002360	HP:0002360	Sleep disturbance	0	ADGRL1 CL E G H	22859	20973	OMIM:620065
HP:0002360	HP:0002360	Sleep disturbance	0	ADH1C CL E G H	126	251	OMIM:168600	Parkinson disease, late-onset	.	4
HP:0002360	HP:0002360	Sleep disturbance	0	ADNP CL E G H	23394	15766	ORPHA:404448	ADNP syndrome	HP:0040283 - Occasional	47
HP:0002360	HP:0002360	Sleep disturbance	0	AFF4 CL E G H	27125	17869	OMIM:616368	CHOPS syndrome		6
HP:0002360	HP:0002360	Sleep disturbance	0	AFF4 CL E G H	27125	17869	ORPHA:444077	Cognitive impairment-coarse facies-heart defects-obesity-pulmonary involvement-short stature-skeletal dysplasia syndrome		6
HP:0002360	HP:0002360	Sleep disturbance	0	AGA CL E G H	175	318	ORPHA:93	Aspartylglucosaminuria	HP:0040283 - Occasional	76
HP:0002360	HP:0002360	Sleep disturbance	0	AGRN CL E G H	375790	329	ORPHA:98914	Presynaptic congenital myasthenic syndromes		127
HP:0002360	HP:0002360	Sleep disturbance	0	AHDC1 CL E G H	27245	25230	ORPHA:412069	AHDC1-related intellectual disability-obstructive sleep apnea-mild dysmorphism syndrome		36
HP:0002360	HP:0002360	Sleep disturbance	0	AHDC1 CL E G H	27245	25230	OMIM:615829	Xia-Gibbs syndrome		36
HP:0002360	HP:0002360	Sleep disturbance	0	AIFM1 CL E G H	9131	8768	ORPHA:101078	X-linked Charcot-Marie-Tooth disease type 4	HP:0040283 - Occasional	60
HP:0002360	HP:0002360	Sleep disturbance	0	AIP CL E G H	9049	358	ORPHA:963	Acromegaly		95
HP:0002360	HP:0002360	Sleep disturbance	0	AKT1 CL E G H	207	391	ORPHA:2495	Meningioma		54
HP:0002360	HP:0002360	Sleep disturbance	0	ALDH4A1 CL E G H	8659	406	ORPHA:79101	Hyperprolinemia type 2	HP:0040282 - Frequent	74
HP:0002360	HP:0002360	Sleep disturbance	0	ALG13 CL E G H	79868	30881	OMIM:300884	Epileptic encephalopathy, early infantile, 36		96
HP:0002360	HP:0002360	Sleep disturbance	0	ALMS1 CL E G H	7840	428	ORPHA:64	Alström syndrome	HP:0040284 - Very rare	404
HP:0002360	HP:0002360	Sleep disturbance	0	ANK3 CL E G H	288	494	ORPHA:356996	ANK3-related intellectual disability-sleep disturbance syndrome	HP:0040282 - Frequent	176
HP:0002360	HP:0002360	Sleep disturbance	0	ANK3 CL E G H	288	494	OMIM:615493	Mental retardation, autosomal recessive 37	.	176
HP:0002360	HP:0002360	Sleep disturbance	0	AP3B2 CL E G H	8120	567	OMIM:617276	EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 48; EIEE48		7
HP:0002360	HP:0002360	Sleep disturbance	0	APOE CL E G H	348	613	OMIM:606889	Alzheimer disease 4		39
HP:0002360	HP:0002360	Sleep disturbance	0	ARCN1 CL E G H	372	649	OMIM:617164	Short stature, rhizomelic, with microcephaly, micrognathia, and developmental delay		3
HP:0002360	HP:0002360	Sleep disturbance	0	ARL3 CL E G H	403	694	OMIM:618161	JOUBERT SYNDROME 35; JBTS35		1
HP:0002360	HP:0002360	Sleep disturbance	0	ARNT2 CL E G H	9915	16876	ORPHA:3157	Septo-optic dysplasia spectrum	HP:0040283 - Occasional
HP:0002360	HP:0002360	Sleep disturbance	0	ARSB CL E G H	411	714	OMIM:253200	Mucopolysaccharidosis, type VI		120
HP:0002360	HP:0002360	Sleep disturbance	0	ARX CL E G H	170302	18060	ORPHA:1934	Early infantile epileptic encephalopathy	HP:0040282 - Frequent	166
HP:0002360	HP:0002360	Sleep disturbance	0	ASCL1 CL E G H	429	738	ORPHA:99803	Haddad syndrome		15
HP:0002360	HP:0002360	Sleep disturbance	0	ASH1L CL E G H	55870	19088	OMIM:617796	Mental retardation, autosomal dominant 52		1
HP:0002360	HP:0002360	Sleep disturbance	0	ASPA CL E G H	443	756	ORPHA:314911	Severe Canavan disease	HP:0040282 - Frequent	48
HP:0002360	HP:0002360	Sleep disturbance	0	ASXL1 CL E G H	171023	18318	ORPHA:97297	Bohring-Opitz syndrome	HP:0040282 - Frequent	145
HP:0002360	HP:0002360	Sleep disturbance	0	ASXL3 CL E G H	80816	29357	ORPHA:352577	Bainbridge-Ropers syndrome	HP:0040283 - Occasional	49
HP:0002360	HP:0002360	Sleep disturbance	0	ATAD1 CL E G H	84896	25903	ORPHA:3197	Hereditary hyperekplexia	HP:0040282 - Frequent
HP:0002360	HP:0002360	Sleep disturbance	0	ATAD3A CL E G H	55210	25567	ORPHA:496790	Ocular anomalies-axonal neuropathy-developmental delay syndrome	HP:0040283 - Occasional	5
HP:0002360	HP:0002360	Sleep disturbance	0	ATN1 CL E G H	1822	3033	OMIM:618494	Congenital hypotonia, epilepsy, developmental delay, and digital anomalies		16
HP:0002360	HP:0002360	Sleep disturbance	0	ATP10A CL E G H	57194	13542	ORPHA:411515	Angelman syndrome due to imprinting defect in 15q11-q13		4
HP:0002360	HP:0002360	Sleep disturbance	0	ATP1A2 CL E G H	477	800	OMIM:619605	DEVELOPMENTAL AND EPILEPTIC ENCEPHALOPATHY 98; DEE98		239
HP:0002360	HP:0002360	Sleep disturbance	0	ATP7B CL E G H	540	870	OMIM:277900	Wilson disease		315
HP:0002360	HP:0002360	Sleep disturbance	0	ATP8B1 CL E G H	5205	3706	ORPHA:69665	Intrahepatic cholestasis of pregnancy		144
HP:0002360	HP:0002360	Sleep disturbance	0	ATXN10 CL E G H	25814	10549	ORPHA:98761	Spinocerebellar ataxia type 10	HP:0040283 - Occasional	9
HP:0002360	HP:0002360	Sleep disturbance	0	ATXN2 CL E G H	6311	10555	OMIM:168600	Parkinson disease, late-onset	.	11
HP:0002360	HP:0002360	Sleep disturbance	0	ATXN3 CL E G H	4287	7106	ORPHA:276238	Machado-Joseph disease type 1	HP:0040283 - Occasional	14
HP:0002360	HP:0002360	Sleep disturbance	0	ATXN3 CL E G H	4287	7106	ORPHA:276241	Machado-Joseph disease type 2	HP:0040283 - Occasional	14
HP:0002360	HP:0002360	Sleep disturbance	0	ATXN3 CL E G H	4287	7106	ORPHA:276244	Machado-Joseph disease type 3	HP:0040283 - Occasional	14
HP:0002360	HP:0002360	Sleep disturbance	0	ATXN7 CL E G H	6314	10560	ORPHA:94147	Spinocerebellar ataxia type 7		8
HP:0002360	HP:0002360	Sleep disturbance	0	ATXN8OS CL E G H	6315	10561	OMIM:168600	Parkinson disease, late-onset	.	1
HP:0002360	HP:0002360	Sleep disturbance	0	BAP1 CL E G H	8314	950	ORPHA:2495	Meningioma		184
HP:0002360	HP:0002360	Sleep disturbance	0	BAZ1B CL E G H	9031	961	ORPHA:904	Williams syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	BCL7B CL E G H	9275	1005	ORPHA:904	Williams syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	BICD2 CL E G H	23299	17208	OMIM:615290	Spinal muscular atrophy, lower extremity-predominant, 2, autosomaldominant		46
HP:0002360	HP:0002360	Sleep disturbance	0	BICRA CL E G H	29998	4332	OMIM:619325	COFFIN-SIRIS SYNDROME 12; CSS12		2
HP:0002360	HP:0002360	Sleep disturbance	0	BMP2 CL E G H	650	1069	OMIM:617877	Short stature, facial dysmorphism, and skeletal anomalies with or without cardiac anomalies		13
HP:0002360	HP:0002360	Sleep disturbance	0	BRAF CL E G H	673	1097	ORPHA:54595	Craniopharyngioma	HP:0040282 - Frequent	276
HP:0002360	HP:0002360	Sleep disturbance	0	BRD4 CL E G H	23476	13575	ORPHA:199	Cornelia de Lange syndrome	HP:0040282 - Frequent
HP:0002360	HP:0002360	Sleep disturbance	0	BSCL2 CL E G H	26580	15832	ORPHA:363400	Severe neurodegenerative syndrome with lipodystrophy	HP:0040282 - Frequent	105
HP:0002360	HP:0002360	Sleep disturbance	0	BUD23 CL E G H	114049	16405	ORPHA:904	Williams syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	C2CD3 CL E G H	26005	24564	ORPHA:434179	Orofaciodigital syndrome type 14		27
HP:0002360	HP:0002360	Sleep disturbance	0	CA2 CL E G H	760	1373	ORPHA:2785	Osteopetrosis with renal tubular acidosis		29
HP:0002360	HP:0002360	Sleep disturbance	0	CABP4 CL E G H	57010	1386	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy		94
HP:0002360	HP:0002360	Sleep disturbance	0	CACNA1C CL E G H	775	1390	OMIM:620029			572
HP:0002360	HP:0002360	Sleep disturbance	0	CAMK2A CL E G H	815	1460	OMIM:617798	Mental retardation, autosomal dominant 53		1
HP:0002360	HP:0002360	Sleep disturbance	0	CAMK2B CL E G H	816	1461	OMIM:617799	Mental retardation, autosomal dominant 54
HP:0002360	HP:0002360	Sleep disturbance	0	CARS1 CL E G H	833	1493	OMIM:618891	MICROCEPHALY, DEVELOPMENTAL DELAY, AND BRITTLE HAIR SYNDROME; MDBH
HP:0002360	HP:0002360	Sleep disturbance	0	CASK CL E G H	8573	1497	ORPHA:1934	Early infantile epileptic encephalopathy	HP:0040282 - Frequent	118
HP:0002360	HP:0002360	Sleep disturbance	0	CCDC47 CL E G H	57003	24856	OMIM:618268	Trichohepatoneurodevelopmental syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	CDC42BPB CL E G H	9578	1738	OMIM:619841
HP:0002360	HP:0002360	Sleep disturbance	0	CDK13 CL E G H	8621	1733	OMIM:617360	Congenital heart defects, dysmorphic facial features, and intellectual developmental disorder		8
HP:0002360	HP:0002360	Sleep disturbance	0	CDKL5 CL E G H	6792	11411	ORPHA:3095	Atypical Rett syndrome	HP:0040281 - Very frequent	405
HP:0002360	HP:0002360	Sleep disturbance	0	CDKL5 CL E G H	6792	11411	ORPHA:505652	CDKL5-deficiency disorder		405
HP:0002360	HP:0002360	Sleep disturbance	0	CDKL5 CL E G H	6792	11411	ORPHA:1934	Early infantile epileptic encephalopathy	HP:0040282 - Frequent	405
HP:0002360	HP:0002360	Sleep disturbance	0	CDON CL E G H	50937	17104	ORPHA:93925	Alobar holoprosencephaly		200
HP:0002360	HP:0002360	Sleep disturbance	0	CDON CL E G H	50937	17104	ORPHA:93924	Lobar holoprosencephaly		200
HP:0002360	HP:0002360	Sleep disturbance	0	CDON CL E G H	50937	17104	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		200
HP:0002360	HP:0002360	Sleep disturbance	0	CDON CL E G H	50937	17104	ORPHA:220386	Semilobar holoprosencephaly		200
HP:0002360	HP:0002360	Sleep disturbance	0	CEP57 CL E G H	9702	30794	OMIM:614114	Mosaic variegated aneuploidy syndrome 2		17
HP:0002360	HP:0002360	Sleep disturbance	0	CHAMP1 CL E G H	283489	20311	OMIM:616579	Mental retardation, autosomal dominant 40		16
HP:0002360	HP:0002360	Sleep disturbance	0	CHAT CL E G H	1103	1912	ORPHA:98914	Presynaptic congenital myasthenic syndromes		65
HP:0002360	HP:0002360	Sleep disturbance	0	CHD8 CL E G H	57680	20153	OMIM:615032	AUTISM, SUSCEPTIBILITY TO, 18; AUTS18		72
HP:0002360	HP:0002360	Sleep disturbance	0	CHKA CL E G H	1119	1937	OMIM:620023
HP:0002360	HP:0002360	Sleep disturbance	0	CHRNA2 CL E G H	1135	1956	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy		188
HP:0002360	HP:0002360	Sleep disturbance	0	CHRNA4 CL E G H	1137	1958	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy		225
HP:0002360	HP:0002360	Sleep disturbance	0	CHRNB2 CL E G H	1141	1962	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy		88
HP:0002360	HP:0002360	Sleep disturbance	0	CIC CL E G H	23152	14214	OMIM:617600	Mental retardation, autosomal dominant 45		39
HP:0002360	HP:0002360	Sleep disturbance	0	CISD2 CL E G H	493856	24212	ORPHA:3463	Wolfram syndrome	HP:0040283 - Occasional	3
HP:0002360	HP:0002360	Sleep disturbance	0	CLCNKB CL E G H	1188	2027	ORPHA:358	Gitelman syndrome		27
HP:0002360	HP:0002360	Sleep disturbance	0	CLIP2 CL E G H	7461	2586	ORPHA:904	Williams syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	CLN3 CL E G H	1201	2074	ORPHA:228346	CLN3 disease		216
HP:0002360	HP:0002360	Sleep disturbance	0	CLN5 CL E G H	1203	2076	ORPHA:228360	CLN5 disease	HP:0040282 - Frequent	141
HP:0002360	HP:0002360	Sleep disturbance	0	CNOT1 CL E G H	23019	7877	OMIM:619033	VISSERS-BODMER SYNDROME; VIBOS		2
HP:0002360	HP:0002360	Sleep disturbance	0	COA8 CL E G H	84334	20492	ORPHA:436271	Non-progressive predominantly posterior cavitating leukoencephalopathy with peripheral neuropathy
HP:0002360	HP:0002360	Sleep disturbance	0	COL13A1 CL E G H	1305	2190	ORPHA:98914	Presynaptic congenital myasthenic syndromes		6
HP:0002360	HP:0002360	Sleep disturbance	0	COL3A1 CL E G H	1281	2201	ORPHA:286	Vascular Ehlers-Danlos syndrome		749
HP:0002360	HP:0002360	Sleep disturbance	0	COLQ CL E G H	8292	2226	ORPHA:98915	Synaptic congenital myasthenic syndromes		90
HP:0002360	HP:0002360	Sleep disturbance	0	COQ2 CL E G H	27235	25223	ORPHA:227510	Multiple system atrophy, cerebellar type		54
HP:0002360	HP:0002360	Sleep disturbance	0	COQ2 CL E G H	27235	25223	ORPHA:98933	Multiple system atrophy, parkinsonian type		54
HP:0002360	HP:0002360	Sleep disturbance	0	CORIN CL E G H	10699	19012	ORPHA:275555	Preeclampsia	HP:0040284 - Very rare	5
HP:0002360	HP:0002360	Sleep disturbance	0	CPOX CL E G H	1371	2321	OMIM:121300	Coproporphyria		72
HP:0002360	HP:0002360	Sleep disturbance	0	CREBBP CL E G H	1387	2348	OMIM:180849	Rubinstein-Taybi syndrome 1		291
HP:0002360	HP:0002360	Sleep disturbance	0	CREBBP CL E G H	1387	2348	ORPHA:353281	Rubinstein-Taybi syndrome due to 16p13.3 microdeletion		291
HP:0002360	HP:0002360	Sleep disturbance	0	CREBBP CL E G H	1387	2348	ORPHA:353277	Rubinstein-Taybi syndrome due to CREBBP mutations		291
HP:0002360	HP:0002360	Sleep disturbance	0	CRH CL E G H	1392	2355	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy		1
HP:0002360	HP:0002360	Sleep disturbance	0	CRY1 CL E G H	1407	2384	OMIM:614163	Delayed sleep phase disorder, susceptibility to		1
HP:0002360	HP:0002360	Sleep disturbance	0	CSNK1D CL E G H	1453	2452	OMIM:615224	Advanced sleep phase syndrome, familial, 2		2
HP:0002360	HP:0002360	Sleep disturbance	0	CTCF CL E G H	10664	13723	ORPHA:363611	CTCF-related neurodevelopmental disorder	HP:0040283 - Occasional	20
HP:0002360	HP:0002360	Sleep disturbance	0	CTNNB1 CL E G H	1499	2514	ORPHA:54595	Craniopharyngioma	HP:0040282 - Frequent	88
HP:0002360	HP:0002360	Sleep disturbance	0	CTNNB1 CL E G H	1499	2514	ORPHA:404473	Severe intellectual disability-progressive spastic diplegia syndrome	HP:0040283 - Occasional	88
HP:0002360	HP:0002360	Sleep disturbance	0	CTSH CL E G H	1512	2535	ORPHA:2073	Narcolepsy type 1	HP:0040281 - Very frequent	1
HP:0002360	HP:0002360	Sleep disturbance	0	CTSK CL E G H	1513	2536	ORPHA:763	Pycnodysostosis		39
HP:0002360	HP:0002360	Sleep disturbance	0	DBH CL E G H	1621	2689	ORPHA:230	Dopamine beta-hydroxylase deficiency	HP:0040282 - Frequent	80
HP:0002360	HP:0002360	Sleep disturbance	0	DCTN1 CL E G H	1639	2711	OMIM:105400	Amyotrophic lateral sclerosis 1		86
HP:0002360	HP:0002360	Sleep disturbance	0	DCTN1 CL E G H	1639	2711	OMIM:168605	Perry syndrome	.	86
HP:0002360	HP:0002360	Sleep disturbance	0	DCTN1 CL E G H	1639	2711	ORPHA:178509	Perry syndrome	HP:0040281 - Very frequent	86
HP:0002360	HP:0002360	Sleep disturbance	0	DDB1 CL E G H	1642	2717	OMIM:619426	WHITE-KERNOHAN SYNDROME; WHIKERS
HP:0002360	HP:0002360	Sleep disturbance	0	DDC CL E G H	1644	2719	OMIM:608643	Aromatic L-amino acid decarboxylase deficiency		43
HP:0002360	HP:0002360	Sleep disturbance	0	DEAF1 CL E G H	10522	14677	OMIM:617171	Dyskinesia, seizures, and intellectual developmental disorder	.	33
HP:0002360	HP:0002360	Sleep disturbance	0	DEAF1 CL E G H	10522	14677	ORPHA:468620	Intellectual disability-epilepsy-extrapyramidal syndrome	HP:0040281 - Very frequent	33
HP:0002360	HP:0002360	Sleep disturbance	0	DEAF1 CL E G H	10522	14677	ORPHA:819	Smith-Magenis syndrome	HP:0040281 - Very frequent	33
HP:0002360	HP:0002360	Sleep disturbance	0	DEPDC5 CL E G H	9681	18423	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy		172
HP:0002360	HP:0002360	Sleep disturbance	0	DHCR7 CL E G H	1717	2860	OMIM:270400	Smith-Lemli-Opitz syndrome		159
HP:0002360	HP:0002360	Sleep disturbance	0	DHCR7 CL E G H	1717	2860	ORPHA:818	Smith-Lemli-Opitz syndrome	HP:0040282 - Frequent	159
HP:0002360	HP:0002360	Sleep disturbance	0	DISP1 CL E G H	84976	19711	ORPHA:93925	Alobar holoprosencephaly		22
HP:0002360	HP:0002360	Sleep disturbance	0	DISP1 CL E G H	84976	19711	ORPHA:93924	Lobar holoprosencephaly		22
HP:0002360	HP:0002360	Sleep disturbance	0	DISP1 CL E G H	84976	19711	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		22
HP:0002360	HP:0002360	Sleep disturbance	0	DISP1 CL E G H	84976	19711	ORPHA:220386	Semilobar holoprosencephaly		22
HP:0002360	HP:0002360	Sleep disturbance	0	DKK1 CL E G H	22943	2891	ORPHA:268882	Arnold-Chiari malformation type I
HP:0002360	HP:0002360	Sleep disturbance	0	DLL1 CL E G H	28514	2908	ORPHA:93925	Alobar holoprosencephaly		3
HP:0002360	HP:0002360	Sleep disturbance	0	DLL1 CL E G H	28514	2908	ORPHA:93924	Lobar holoprosencephaly		3
HP:0002360	HP:0002360	Sleep disturbance	0	DLL1 CL E G H	28514	2908	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		3
HP:0002360	HP:0002360	Sleep disturbance	0	DLL1 CL E G H	28514	2908	ORPHA:220386	Semilobar holoprosencephaly		3
HP:0002360	HP:0002360	Sleep disturbance	0	DMD CL E G H	1756	2928	OMIM:310200	Duchenne muscular dystrophy		1496
HP:0002360	HP:0002360	Sleep disturbance	0	DMPK CL E G H	1760	2933	ORPHA:589821	Congenital-onset Steinert myotonic dystrophy		152
HP:0002360	HP:0002360	Sleep disturbance	0	DMPK CL E G H	1760	2933	OMIM:160900	Myotonic dystrophy 1		152
HP:0002360	HP:0002360	Sleep disturbance	0	DMXL2 CL E G H	23312	2938	ORPHA:1934	Early infantile epileptic encephalopathy	HP:0040282 - Frequent	3
HP:0002360	HP:0002360	Sleep disturbance	0	DNA2 CL E G H	1763	2939	ORPHA:352470	DNA2-related mitochondrial DNA deletion syndrome		41
HP:0002360	HP:0002360	Sleep disturbance	0	DNA2 CL E G H	1763	2939	OMIM:615156	Progressive external ophthalmoplegia with mitochondrial DNA deletions,autosomal dominant, 6		41
HP:0002360	HP:0002360	Sleep disturbance	0	DNAJC13 CL E G H	23317	30343	ORPHA:411602	Hereditary late-onset Parkinson disease	HP:0040283 - Occasional	2
HP:0002360	HP:0002360	Sleep disturbance	0	DNAJC30 CL E G H	84277	16410	ORPHA:904	Williams syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	DNAJC6 CL E G H	9829	15469	ORPHA:2828	Young-onset Parkinson disease		6
HP:0002360	HP:0002360	Sleep disturbance	0	DNMT1 CL E G H	1786	2976	ORPHA:314404	Autosomal dominant cerebellar ataxia-deafness-narcolepsy syndrome		145
HP:0002360	HP:0002360	Sleep disturbance	0	DNMT1 CL E G H	1786	2976	OMIM:604121	Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant		145
HP:0002360	HP:0002360	Sleep disturbance	0	DNMT1 CL E G H	1786	2976	OMIM:614116	Neuropathy, hereditary sensory, type IE		145
HP:0002360	HP:0002360	Sleep disturbance	0	DOK7 CL E G H	285489	26594	ORPHA:994	Fetal akinesia deformation sequence		91
HP:0002360	HP:0002360	Sleep disturbance	0	DPH1 CL E G H	1801	3003	ORPHA:459061	Craniofacial dysplasia-short stature-ectodermal anomalies-intellectual disability syndrome		3
HP:0002360	HP:0002360	Sleep disturbance	0	DPH5 CL E G H	51611	24270	OMIM:620070
HP:0002360	HP:0002360	Sleep disturbance	0	DPYS CL E G H	1807	3013	OMIM:222748	Dihydropyrimidinuria		44
HP:0002360	HP:0002360	Sleep disturbance	0	DUOX2 CL E G H	50506	13273	ORPHA:226316	Genetic transient congenital hypothyroidism		121
HP:0002360	HP:0002360	Sleep disturbance	0	DYRK1A CL E G H	1859	3091	ORPHA:268261	DYRK1A-related intellectual disability syndrome due to 21q22.13q22.2 microdeletion	HP:0040283 - Occasional	134
HP:0002360	HP:0002360	Sleep disturbance	0	EDN1 CL E G H	1906	3176	ORPHA:137888	Auriculocondylar syndrome		6
HP:0002360	HP:0002360	Sleep disturbance	0	EEF1A2 CL E G H	1917	3192	OMIM:616393	Mental retardation, autosomal dominant 38		60
HP:0002360	HP:0002360	Sleep disturbance	0	EHMT1 CL E G H	79813	24650	OMIM:610253	Kleefstra syndrome		223
HP:0002360	HP:0002360	Sleep disturbance	0	EHMT1 CL E G H	79813	24650	ORPHA:96147	Kleefstra syndrome due to 9q34 microdeletion	HP:0040283 - Occasional	223
HP:0002360	HP:0002360	Sleep disturbance	0	EIF3F CL E G H	8665	3275	OMIM:618295	Intellectual developmental disorder, autosomal recessive 67
HP:0002360	HP:0002360	Sleep disturbance	0	EIF4G1 CL E G H	1981	3296	ORPHA:411602	Hereditary late-onset Parkinson disease	HP:0040283 - Occasional	2
HP:0002360	HP:0002360	Sleep disturbance	0	EIF4H CL E G H	7458	12741	ORPHA:904	Williams syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	ELN CL E G H	2006	3327	ORPHA:904	Williams syndrome		172
HP:0002360	HP:0002360	Sleep disturbance	0	ELN CL E G H	2006	3327	OMIM:194050	Williams-Beuren syndrome		172
HP:0002360	HP:0002360	Sleep disturbance	0	EMC10 CL E G H	284361	27609	OMIM:619264	NEURODEVELOPMENTAL DISORDER WITH DYSMORPHIC FACIES AND VARIABLE SEIZURES; NEDDFAS
HP:0002360	HP:0002360	Sleep disturbance	0	EML1 CL E G H	2009	3330	OMIM:600348	Band heterotopia	.	3
HP:0002360	HP:0002360	Sleep disturbance	0	EP300 CL E G H	2033	3373	OMIM:180849	Rubinstein-Taybi syndrome 1		250
HP:0002360	HP:0002360	Sleep disturbance	0	EP300 CL E G H	2033	3373	ORPHA:353284	Rubinstein-Taybi syndrome due to EP300 haploinsufficiency		250
HP:0002360	HP:0002360	Sleep disturbance	0	EPG5 CL E G H	57724	29331	ORPHA:1493	Vici syndrome	HP:0040283 - Occasional	40
HP:0002360	HP:0002360	Sleep disturbance	0	EPM2A CL E G H	7957	3413	ORPHA:501	Lafora disease	HP:0040283 - Occasional	83
HP:0002360	HP:0002360	Sleep disturbance	0	ERCC4 CL E G H	2072	3436	ORPHA:90321	Cockayne syndrome type 1	HP:0040283 - Occasional	158
HP:0002360	HP:0002360	Sleep disturbance	0	ERCC6 CL E G H	2074	3438	ORPHA:90321	Cockayne syndrome type 1	HP:0040283 - Occasional	199
HP:0002360	HP:0002360	Sleep disturbance	0	ERCC8 CL E G H	1161	3439	ORPHA:90321	Cockayne syndrome type 1	HP:0040283 - Occasional	55
HP:0002360	HP:0002360	Sleep disturbance	0	EXOC2 CL E G H	55770	24968	OMIM:619306	NEURODEVELOPMENTAL DISORDER WITH DYSMORPHIC FACIES AND CEREBELLAR HYPOPLASIA; NEDFACH		1
HP:0002360	HP:0002360	Sleep disturbance	0	FARS2 CL E G H	10667	21062	ORPHA:466722	Autosomal recessive spastic paraplegia type 77		36
HP:0002360	HP:0002360	Sleep disturbance	0	FBP1 CL E G H	2203	3606	ORPHA:348	Fructose-1,6-bisphosphatase deficiency		64
HP:0002360	HP:0002360	Sleep disturbance	0	FBXL3 CL E G H	26224	13599	OMIM:606220	Intellectual developmental disorder with short stature, facial anomalies, and speech defects
HP:0002360	HP:0002360	Sleep disturbance	0	FBXO11 CL E G H	80204	13590	OMIM:618089	Intellectual developmental disorder with dysmorphic facies and behavioral abnormalities		7
HP:0002360	HP:0002360	Sleep disturbance	0	FBXO28 CL E G H	23219	29046	OMIM:619777	DEVELOPMENTAL AND EPILEPTIC ENCEPHALOPATHY 100; DEE100
HP:0002360	HP:0002360	Sleep disturbance	0	FBXO7 CL E G H	25793	13586	ORPHA:171695	Parkinsonian-pyramidal syndrome	HP:0040282 - Frequent	36
HP:0002360	HP:0002360	Sleep disturbance	0	FGF8 CL E G H	2253	3686	ORPHA:93925	Alobar holoprosencephaly		17
HP:0002360	HP:0002360	Sleep disturbance	0	FGF8 CL E G H	2253	3686	ORPHA:93924	Lobar holoprosencephaly		17
HP:0002360	HP:0002360	Sleep disturbance	0	FGF8 CL E G H	2253	3686	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		17
HP:0002360	HP:0002360	Sleep disturbance	0	FGF8 CL E G H	2253	3686	ORPHA:220386	Semilobar holoprosencephaly		17
HP:0002360	HP:0002360	Sleep disturbance	0	FGFR1 CL E G H	2260	3688	ORPHA:93924	Lobar holoprosencephaly		172
HP:0002360	HP:0002360	Sleep disturbance	0	FGFR1 CL E G H	2260	3688	ORPHA:220386	Semilobar holoprosencephaly		172
HP:0002360	HP:0002360	Sleep disturbance	0	FGFR1 CL E G H	2260	3688	ORPHA:3157	Septo-optic dysplasia spectrum	HP:0040283 - Occasional	172
HP:0002360	HP:0002360	Sleep disturbance	0	FGFR2 CL E G H	2263	3689	OMIM:123500	Crouzon syndrome		175
HP:0002360	HP:0002360	Sleep disturbance	0	FGFR2 CL E G H	2263	3689	ORPHA:794	Saethre-Chotzen syndrome		175
HP:0002360	HP:0002360	Sleep disturbance	0	FGFR3 CL E G H	2261	3690	ORPHA:15	Achondroplasia		145
HP:0002360	HP:0002360	Sleep disturbance	0	FGFR3 CL E G H	2261	3690	OMIM:616482	Achondroplasia, severe, with developmental delay and acanthosis nigricans		145
HP:0002360	HP:0002360	Sleep disturbance	0	FGFR3 CL E G H	2261	3690	ORPHA:429	Hypochondroplasia		145
HP:0002360	HP:0002360	Sleep disturbance	0	FGFR3 CL E G H	2261	3690	ORPHA:794	Saethre-Chotzen syndrome		145
HP:0002360	HP:0002360	Sleep disturbance	0	FKBP6 CL E G H	8468	3722	ORPHA:904	Williams syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	FKRP CL E G H	79147	17997	OMIM:236670	Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 1		157
HP:0002360	HP:0002360	Sleep disturbance	0	FKTN CL E G H	2218	3622	OMIM:236670	Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 1		184
HP:0002360	HP:0002360	Sleep disturbance	0	FLCN CL E G H	201163	27310	OMIM:610883	Potocki-Lupski syndrome		332
HP:0002360	HP:0002360	Sleep disturbance	0	FLII CL E G H	2314	3750	ORPHA:819	Smith-Magenis syndrome	HP:0040281 - Very frequent
HP:0002360	HP:0002360	Sleep disturbance	0	FLT1 CL E G H	2321	3763	ORPHA:275555	Preeclampsia	HP:0040284 - Very rare	11
HP:0002360	HP:0002360	Sleep disturbance	0	FMR1 CL E G H	2332	3775	ORPHA:449291	Symptomatic form of fragile X syndrome in female carriers	HP:0040284 - Very rare	30
HP:0002360	HP:0002360	Sleep disturbance	0	FOXE1 CL E G H	2304	3806	ORPHA:95713	Athyreosis		9
HP:0002360	HP:0002360	Sleep disturbance	0	FOXH1 CL E G H	8928	3814	ORPHA:93925	Alobar holoprosencephaly		48
HP:0002360	HP:0002360	Sleep disturbance	0	FOXH1 CL E G H	8928	3814	ORPHA:93924	Lobar holoprosencephaly		48
HP:0002360	HP:0002360	Sleep disturbance	0	FOXH1 CL E G H	8928	3814	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		48
HP:0002360	HP:0002360	Sleep disturbance	0	FOXH1 CL E G H	8928	3814	ORPHA:220386	Semilobar holoprosencephaly		48
HP:0002360	HP:0002360	Sleep disturbance	0	FTL CL E G H	2512	3999	OMIM:615604	L-ferritin deficiency, dominant and recessive		33
HP:0002360	HP:0002360	Sleep disturbance	0	FXR1 CL E G H	8087	4023	OMIM:618823	MYOPATHY, CONGENITAL PROXIMAL, WITH MINICORE LESIONS; MYOPMIL
HP:0002360	HP:0002360	Sleep disturbance	0	FXR1 CL E G H	8087	4023	OMIM:618822	MYOPATHY, CONGENITAL, WITH RESPIRATORY INSUFFICIENCY AND BONE FRACTURES; MYORIBF
HP:0002360	HP:0002360	Sleep disturbance	0	GABBR2 CL E G H	9568	4507	ORPHA:3095	Atypical Rett syndrome	HP:0040281 - Very frequent	5
HP:0002360	HP:0002360	Sleep disturbance	0	GABBR2 CL E G H	9568	4507	OMIM:617904	Epileptic encephalopathy, early infantile, 59	.	5
HP:0002360	HP:0002360	Sleep disturbance	0	GABBR2 CL E G H	9568	4507	OMIM:617903	Neurodevelopmental disorder with poor language and loss of hand skills	.	5
HP:0002360	HP:0002360	Sleep disturbance	0	GABRB3 CL E G H	2562	4083	OMIM:617113	Epileptic encephalopathy, early infantile, 43		57
HP:0002360	HP:0002360	Sleep disturbance	0	GABRG2 CL E G H	2566	4087	ORPHA:1945	Rolandic epilepsy		139
HP:0002360	HP:0002360	Sleep disturbance	0	GALNT2 CL E G H	2590	4124	OMIM:618885	CONGENITAL DISORDER OF GLYCOSYLATION, TYPE IIt; CDG2T
HP:0002360	HP:0002360	Sleep disturbance	0	GAS1 CL E G H	2619	4165	ORPHA:93925	Alobar holoprosencephaly		2
HP:0002360	HP:0002360	Sleep disturbance	0	GAS1 CL E G H	2619	4165	ORPHA:93924	Lobar holoprosencephaly		2
HP:0002360	HP:0002360	Sleep disturbance	0	GAS1 CL E G H	2619	4165	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		2
HP:0002360	HP:0002360	Sleep disturbance	0	GAS1 CL E G H	2619	4165	ORPHA:220386	Semilobar holoprosencephaly		2
HP:0002360	HP:0002360	Sleep disturbance	0	GATAD2B CL E G H	57459	30778	ORPHA:363686	Severe intellectual disability-poor language-strabismus-grimacing face-long fingers syndrome	HP:0040283 - Occasional	33
HP:0002360	HP:0002360	Sleep disturbance	0	GBA1 CL E G H	2629	4177	ORPHA:411602	Hereditary late-onset Parkinson disease	HP:0040283 - Occasional
HP:0002360	HP:0002360	Sleep disturbance	0	GBA1 CL E G H	2629	4177	OMIM:168600	Parkinson disease, late-onset	.
HP:0002360	HP:0002360	Sleep disturbance	0	GCH1 CL E G H	2643	4193	ORPHA:98808	Autosomal dominant dopa-responsive dystonia	HP:0040282 - Frequent	86
HP:0002360	HP:0002360	Sleep disturbance	0	GFAP CL E G H	2670	4235	ORPHA:363722	Alexander disease type II		188
HP:0002360	HP:0002360	Sleep disturbance	0	GIGYF2 CL E G H	26058	11960	ORPHA:411602	Hereditary late-onset Parkinson disease	HP:0040283 - Occasional	8
HP:0002360	HP:0002360	Sleep disturbance	0	GJB1 CL E G H	2705	4283	ORPHA:101075	X-linked Charcot-Marie-Tooth disease type 1		107
HP:0002360	HP:0002360	Sleep disturbance	0	GLI2 CL E G H	2736	4318	ORPHA:93925	Alobar holoprosencephaly		173
HP:0002360	HP:0002360	Sleep disturbance	0	GLI2 CL E G H	2736	4318	ORPHA:93924	Lobar holoprosencephaly		173
HP:0002360	HP:0002360	Sleep disturbance	0	GLI2 CL E G H	2736	4318	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		173
HP:0002360	HP:0002360	Sleep disturbance	0	GLI2 CL E G H	2736	4318	ORPHA:220386	Semilobar holoprosencephaly		173
HP:0002360	HP:0002360	Sleep disturbance	0	GLRA1 CL E G H	2741	4326	ORPHA:3197	Hereditary hyperekplexia	HP:0040282 - Frequent	63
HP:0002360	HP:0002360	Sleep disturbance	0	GLRB CL E G H	2743	4329	ORPHA:3197	Hereditary hyperekplexia	HP:0040282 - Frequent	46
HP:0002360	HP:0002360	Sleep disturbance	0	GLUD2 CL E G H	2747	4336	OMIM:168600	Parkinson disease, late-onset	.	1
HP:0002360	HP:0002360	Sleep disturbance	0	GNAI3 CL E G H	2773	4387	ORPHA:137888	Auriculocondylar syndrome		2
HP:0002360	HP:0002360	Sleep disturbance	0	GNAI3 CL E G H	2773	4387	OMIM:602483	Auriculocondylar syndrome 1		2
HP:0002360	HP:0002360	Sleep disturbance	0	GNAO1 CL E G H	2775	4389	ORPHA:1934	Early infantile epileptic encephalopathy	HP:0040282 - Frequent	36
HP:0002360	HP:0002360	Sleep disturbance	0	GNE CL E G H	10020	23657	ORPHA:3166	Sialuria		173
HP:0002360	HP:0002360	Sleep disturbance	0	GNE CL E G H	10020	23657	OMIM:269921	SIALURIA		173
HP:0002360	HP:0002360	Sleep disturbance	0	GNPTAB CL E G H	79158	29670	ORPHA:576	Mucolipidosis type II		240
HP:0002360	HP:0002360	Sleep disturbance	0	GNS CL E G H	2799	4422	OMIM:252940	Mucopolysaccharidosis, type IIID	.	69
HP:0002360	HP:0002360	Sleep disturbance	0	GPHN CL E G H	10243	15465	ORPHA:3197	Hereditary hyperekplexia	HP:0040282 - Frequent	18
HP:0002360	HP:0002360	Sleep disturbance	0	GPR101 CL E G H	83550	14963	ORPHA:963	Acromegaly		5
HP:0002360	HP:0002360	Sleep disturbance	0	GPR101 CL E G H	83550	14963	OMIM:300942	Chromosome Xq26.3 duplication syndrome		5
HP:0002360	HP:0002360	Sleep disturbance	0	GRB10 CL E G H	2887	4564	ORPHA:96182	Silver-Russell syndrome due to maternal uniparental disomy of chromosome 7
HP:0002360	HP:0002360	Sleep disturbance	0	GRIA1 CL E G H	2890	4571	OMIM:619931			3
HP:0002360	HP:0002360	Sleep disturbance	0	GRIA1 CL E G H	2890	4571	OMIM:619927			3
HP:0002360	HP:0002360	Sleep disturbance	0	GRIA3 CL E G H	2892	4573	ORPHA:364028	X-linked intellectual disability due to GRIA3 mutations	HP:0040283 - Occasional	30
HP:0002360	HP:0002360	Sleep disturbance	0	GRIN1 CL E G H	2902	4584	ORPHA:208447	Bilateral generalized polymicrogyria	HP:0040283 - Occasional	108
HP:0002360	HP:0002360	Sleep disturbance	0	GRIN1 CL E G H	2902	4584	ORPHA:1934	Early infantile epileptic encephalopathy	HP:0040282 - Frequent	108
HP:0002360	HP:0002360	Sleep disturbance	0	GRIN2A CL E G H	2903	4585	ORPHA:98818	Landau-Kleffner syndrome	HP:0040283 - Occasional	434
HP:0002360	HP:0002360	Sleep disturbance	0	GRIN2A CL E G H	2903	4585	ORPHA:1945	Rolandic epilepsy		434
HP:0002360	HP:0002360	Sleep disturbance	0	GRM7 CL E G H	2917	4599	ORPHA:1934	Early infantile epileptic encephalopathy	HP:0040282 - Frequent	5
HP:0002360	HP:0002360	Sleep disturbance	0	GSN CL E G H	2934	4620	ORPHA:85448	AGel amyloidosis		53
HP:0002360	HP:0002360	Sleep disturbance	0	GTF2I CL E G H	2969	4659	ORPHA:904	Williams syndrome		1
HP:0002360	HP:0002360	Sleep disturbance	0	GTF2IRD1 CL E G H	9569	4661	ORPHA:904	Williams syndrome		1
HP:0002360	HP:0002360	Sleep disturbance	0	GTF2IRD2 CL E G H	84163	30775	ORPHA:904	Williams syndrome		1
HP:0002360	HP:0002360	Sleep disturbance	0	GUSB CL E G H	2990	4696	OMIM:253220	Mucopolysaccharidosis, type VII		54
HP:0002360	HP:0002360	Sleep disturbance	0	H4C5 CL E G H	8367	4790	OMIM:619950
HP:0002360	HP:0002360	Sleep disturbance	0	HACD1 CL E G H	9200	9639	ORPHA:2020	Congenital fiber-type disproportion myopathy	HP:0040283 - Occasional	2
HP:0002360	HP:0002360	Sleep disturbance	0	HCRT CL E G H	3060	4847	OMIM:161400	Narcolepsy 1		1
HP:0002360	HP:0002360	Sleep disturbance	0	HCRT CL E G H	3060	4847	ORPHA:2073	Narcolepsy type 1	HP:0040281 - Very frequent	1
HP:0002360	HP:0002360	Sleep disturbance	0	HCRT CL E G H	3060	4847	ORPHA:83465	Narcolepsy type 2	HP:0040281 - Very frequent	1
HP:0002360	HP:0002360	Sleep disturbance	0	HDAC4 CL E G H	9759	14063	ORPHA:1001	2q37 microdeletion syndrome	HP:0040283 - Occasional	33
HP:0002360	HP:0002360	Sleep disturbance	0	HDAC4 CL E G H	9759	14063	OMIM:619797	NEURODEVELOPMENTAL DISORDER WITH CENTRAL HYPOTONIA AND DYSMORPHIC FACIES; NEDCHF		33
HP:0002360	HP:0002360	Sleep disturbance	0	HDAC8 CL E G H	55869	13315	ORPHA:199	Cornelia de Lange syndrome	HP:0040282 - Frequent	37
HP:0002360	HP:0002360	Sleep disturbance	0	HDC CL E G H	3067	4855	OMIM:137580	Gilles de la tourette syndrome	.	1
HP:0002360	HP:0002360	Sleep disturbance	0	HEPHL1 CL E G H	341208	30477	OMIM:261990	PILI TORTI AND DEVELOPMENTAL DELAY
HP:0002360	HP:0002360	Sleep disturbance	0	HERC2 CL E G H	8924	4868	OMIM:176270	Prader-Willi syndrome		38
HP:0002360	HP:0002360	Sleep disturbance	0	HESX1 CL E G H	8820	4877	ORPHA:3157	Septo-optic dysplasia spectrum	HP:0040283 - Occasional	21
HP:0002360	HP:0002360	Sleep disturbance	0	HEXB CL E G H	3074	4879	ORPHA:309162	Sandhoff disease, juvenile form		80
HP:0002360	HP:0002360	Sleep disturbance	0	HGSNAT CL E G H	138050	26527	OMIM:252930	Mucopolysaccharidosis type IIIC	.	86
HP:0002360	HP:0002360	Sleep disturbance	0	HIBCH CL E G H	26275	4908	ORPHA:88639	Neurodegeneration due to 3-hydroxyisobutyryl-CoA hydrolase deficiency	HP:0040282 - Frequent	32
HP:0002360	HP:0002360	Sleep disturbance	0	HLA-DQB1 CL E G H	3119	4944	ORPHA:2073	Narcolepsy type 1	HP:0040281 - Very frequent
HP:0002360	HP:0002360	Sleep disturbance	0	HLA-DQB1 CL E G H	3119	4944	ORPHA:83465	Narcolepsy type 2	HP:0040281 - Very frequent
HP:0002360	HP:0002360	Sleep disturbance	0	HLA-DRB1 CL E G H	3123	4948	ORPHA:2073	Narcolepsy type 1	HP:0040281 - Very frequent	2
HP:0002360	HP:0002360	Sleep disturbance	0	HLA-DRB1 CL E G H	3123	4948	ORPHA:83465	Narcolepsy type 2	HP:0040281 - Very frequent	2
HP:0002360	HP:0002360	Sleep disturbance	0	HMBS CL E G H	3145	4982	ORPHA:79276	Acute intermittent porphyria		81
HP:0002360	HP:0002360	Sleep disturbance	0	HMGCL CL E G H	3155	5005	OMIM:246450	3-Hydroxy-3-Methylglutaryl-Coa lyase deficiency		35
HP:0002360	HP:0002360	Sleep disturbance	0	HRAS CL E G H	3265	5173	OMIM:218040	Costello syndrome		113
HP:0002360	HP:0002360	Sleep disturbance	0	HTRA2 CL E G H	27429	14348	ORPHA:2828	Young-onset Parkinson disease		39
HP:0002360	HP:0002360	Sleep disturbance	0	HTT CL E G H	3064	4851	ORPHA:399	Huntington disease		12
HP:0002360	HP:0002360	Sleep disturbance	0	HUWE1 CL E G H	10075	30892	OMIM:309590	Mental retardation, x-linked syndromic, Turner type		98
HP:0002360	HP:0002360	Sleep disturbance	0	IDS CL E G H	3423	5389	ORPHA:217093	Mucopolysaccharidosis type 2, attenuated form	HP:0040283 - Occasional	86
HP:0002360	HP:0002360	Sleep disturbance	0	IDS CL E G H	3423	5389	ORPHA:217085	Mucopolysaccharidosis type 2, severe form	HP:0040282 - Frequent	86
HP:0002360	HP:0002360	Sleep disturbance	0	IDS CL E G H	3423	5389	OMIM:309900	Mucopolysaccharidosis, type II		86
HP:0002360	HP:0002360	Sleep disturbance	0	IDUA CL E G H	3425	5391	ORPHA:93473	Hurler syndrome	HP:0040282 - Frequent	115
HP:0002360	HP:0002360	Sleep disturbance	0	IDUA CL E G H	3425	5391	OMIM:607015	Hurler-Scheie syndrome		115
HP:0002360	HP:0002360	Sleep disturbance	0	IDUA CL E G H	3425	5391	OMIM:607016	Scheie syndrome		115
HP:0002360	HP:0002360	Sleep disturbance	0	IFNG CL E G H	3458	5438	ORPHA:805	Tuberous sclerosis complex	HP:0040282 - Frequent	23
HP:0002360	HP:0002360	Sleep disturbance	0	IL12A CL E G H	3592	5969	ORPHA:186	Primary biliary cholangitis	HP:0040283 - Occasional
HP:0002360	HP:0002360	Sleep disturbance	0	IL12RB1 CL E G H	3594	5971	ORPHA:186	Primary biliary cholangitis	HP:0040283 - Occasional	46
HP:0002360	HP:0002360	Sleep disturbance	0	IMPDH2 CL E G H	3615	6053	ORPHA:98808	Autosomal dominant dopa-responsive dystonia	HP:0040282 - Frequent	1
HP:0002360	HP:0002360	Sleep disturbance	0	IPW CL E G H	3653	6109	OMIM:176270	Prader-Willi syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	IQSEC2 CL E G H	23096	29059	ORPHA:819	Smith-Magenis syndrome	HP:0040281 - Very frequent	119
HP:0002360	HP:0002360	Sleep disturbance	0	IRF4 CL E G H	3662	6119	ORPHA:3452	Whipple disease	HP:0040282 - Frequent	1
HP:0002360	HP:0002360	Sleep disturbance	0	IRF5 CL E G H	3663	6120	ORPHA:186	Primary biliary cholangitis	HP:0040283 - Occasional	4
HP:0002360	HP:0002360	Sleep disturbance	0	ITGA7 CL E G H	3679	6143	ORPHA:2020	Congenital fiber-type disproportion myopathy	HP:0040283 - Occasional	127
HP:0002360	HP:0002360	Sleep disturbance	0	KAT5 CL E G H	10524	5275	OMIM:619103	NEURODEVELOPMENTAL DISORDER WITH DYSMORPHIC FACIES, SLEEP DISTURBANCE, AND BRAIN ABNORMALITIES; NEDFASB		1
HP:0002360	HP:0002360	Sleep disturbance	0	KAT6A CL E G H	7994	13013	OMIM:616268	Arboleda-Tham syndrome		34
HP:0002360	HP:0002360	Sleep disturbance	0	KCNA1 CL E G H	3736	6218	ORPHA:1934	Early infantile epileptic encephalopathy	HP:0040282 - Frequent	145
HP:0002360	HP:0002360	Sleep disturbance	0	KCNT1 CL E G H	57582	18865	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy		321
HP:0002360	HP:0002360	Sleep disturbance	0	KIF11 CL E G H	3832	6388	OMIM:152950	Microcephaly with or without chorioretinopathy, lymphedema, or mental retardation	HP:0040283 - Occasional	46
HP:0002360	HP:0002360	Sleep disturbance	0	KIF15 CL E G H	56992	17273	ORPHA:261323	21q22.11q22.12 microdeletion syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	KMT5B CL E G H	51111	24283	OMIM:617788	Mental retardation, autosomal dominant 51		2
HP:0002360	HP:0002360	Sleep disturbance	0	LAMB2 CL E G H	3913	6487	ORPHA:98915	Synaptic congenital myasthenic syndromes		92
HP:0002360	HP:0002360	Sleep disturbance	0	LARGE1 CL E G H	9215	6511	OMIM:236670	Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 1		136
HP:0002360	HP:0002360	Sleep disturbance	0	LARP7 CL E G H	51574	24912	ORPHA:319671	Alazami syndrome	HP:0040283 - Occasional	16
HP:0002360	HP:0002360	Sleep disturbance	0	LIAS CL E G H	11019	16429	OMIM:614462	Hyperglycinemia, lactic acidosis, and seizures	.	31
HP:0002360	HP:0002360	Sleep disturbance	0	LIMK1 CL E G H	3984	6613	ORPHA:904	Williams syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	LRPPRC CL E G H	10128	15714	ORPHA:70472	Congenital lactic acidosis, Saguenay-Lac-Saint-Jean type		191
HP:0002360	HP:0002360	Sleep disturbance	0	LRRC32 CL E G H	2615	4161	OMIM:619074	CLEFT PALATE, PROLIFERATIVE RETINOPATHY, AND DEVELOPMENTAL DELAY; CPPRDD
HP:0002360	HP:0002360	Sleep disturbance	0	LRRK2 CL E G H	120892	18618	ORPHA:411602	Hereditary late-onset Parkinson disease	HP:0040283 - Occasional	221
HP:0002360	HP:0002360	Sleep disturbance	0	LRRK2 CL E G H	120892	18618	ORPHA:2828	Young-onset Parkinson disease		221
HP:0002360	HP:0002360	Sleep disturbance	0	LTBP3 CL E G H	4054	6716	OMIM:617809	Geleophysic dysplasia 3		12
HP:0002360	HP:0002360	Sleep disturbance	0	MAGEL2 CL E G H	54551	6814	ORPHA:398069	MAGEL2-related Prader-Willi-like syndrome		63
HP:0002360	HP:0002360	Sleep disturbance	0	MAGEL2 CL E G H	54551	6814	OMIM:176270	Prader-Willi syndrome		63
HP:0002360	HP:0002360	Sleep disturbance	0	MAGEL2 CL E G H	54551	6814	ORPHA:98754	Prader-Willi syndrome due to maternal uniparental disomy of chromosome 15	HP:0040283 - Occasional	63
HP:0002360	HP:0002360	Sleep disturbance	0	MAGEL2 CL E G H	54551	6814	ORPHA:177901	Prader-Willi syndrome due to paternal deletion of 15q11q13 type 1	HP:0040282 - Frequent	63
HP:0002360	HP:0002360	Sleep disturbance	0	MAGEL2 CL E G H	54551	6814	ORPHA:177904	Prader-Willi syndrome due to paternal deletion of 15q11q13 type 2	HP:0040282 - Frequent	63
HP:0002360	HP:0002360	Sleep disturbance	0	MAGEL2 CL E G H	54551	6814	OMIM:615547	Schaaf-Yang syndrome		63
HP:0002360	HP:0002360	Sleep disturbance	0	MAP3K20 CL E G H	51776	17797	ORPHA:2020	Congenital fiber-type disproportion myopathy	HP:0040283 - Occasional	2
HP:0002360	HP:0002360	Sleep disturbance	0	MAPT CL E G H	4137	6893	OMIM:168600	Parkinson disease, late-onset	.	140
HP:0002360	HP:0002360	Sleep disturbance	0	MBD5 CL E G H	55777	20444	ORPHA:228402	2q23.1 microdeletion syndrome	HP:0040282 - Frequent	252
HP:0002360	HP:0002360	Sleep disturbance	0	MCM3AP CL E G H	8888	6946	OMIM:618124	Peripheral neuropathy, autosomal recessive, with or without impaired intellectual development		3
HP:0002360	HP:0002360	Sleep disturbance	0	MECP2 CL E G H	4204	6990	ORPHA:3095	Atypical Rett syndrome	HP:0040281 - Very frequent	950
HP:0002360	HP:0002360	Sleep disturbance	0	MECP2 CL E G H	4204	6990	OMIM:300260	Mental retardation, x-linked syndromic, Lubs type		950
HP:0002360	HP:0002360	Sleep disturbance	0	MECP2 CL E G H	4204	6990	ORPHA:778	Rett syndrome	HP:0040283 - Occasional	950
HP:0002360	HP:0002360	Sleep disturbance	0	MECP2 CL E G H	4204	6990	ORPHA:3077	X-linked intellectual disability-psychosis-macroorchidism syndrome	HP:0040281 - Very frequent	950
HP:0002360	HP:0002360	Sleep disturbance	0	MED12L CL E G H	116931	16050	OMIM:618872	NIZON-ISIDOR SYNDROME; NIZIDS
HP:0002360	HP:0002360	Sleep disturbance	0	MED23 CL E G H	9439	2372	OMIM:614249	Mental retardation, autosomal recessive 18		25
HP:0002360	HP:0002360	Sleep disturbance	0	MED27 CL E G H	9442	2377	OMIM:619286	NEURODEVELOPMENTAL DISORDER WITH SPASTICITY, CATARACTS, AND CEREBELLAR HYPOPLASIA; NEDSCAC
HP:0002360	HP:0002360	Sleep disturbance	0	MEN1 CL E G H	4221	7010	ORPHA:97279	Insulinoma		462
HP:0002360	HP:0002360	Sleep disturbance	0	METTL27 CL E G H	155368	19068	ORPHA:904	Williams syndrome		1
HP:0002360	HP:0002360	Sleep disturbance	0	MFN2 CL E G H	9927	16877	ORPHA:99947	Autosomal dominant Charcot-Marie-Tooth disease type 2A2		203
HP:0002360	HP:0002360	Sleep disturbance	0	MFSD8 CL E G H	256471	28486	OMIM:610951	Ceroid lipofuscinosis, neuronal, 7	.	120
HP:0002360	HP:0002360	Sleep disturbance	0	MKRN3 CL E G H	7681	7114	OMIM:176270	Prader-Willi syndrome		5
HP:0002360	HP:0002360	Sleep disturbance	0	MKRN3-AS1 CL E G H	10108		OMIM:176270	Prader-Willi syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	MLXIPL CL E G H	51085	12744	ORPHA:904	Williams syndrome		1
HP:0002360	HP:0002360	Sleep disturbance	0	MLXIPL CL E G H	51085	12744	OMIM:194050	Williams-Beuren syndrome		1
HP:0002360	HP:0002360	Sleep disturbance	0	MMEL1 CL E G H	79258	14668	ORPHA:186	Primary biliary cholangitis	HP:0040283 - Occasional
HP:0002360	HP:0002360	Sleep disturbance	0	MOG CL E G H	4340	7197	OMIM:614250	Narcolepsy 7		1
HP:0002360	HP:0002360	Sleep disturbance	0	MOG CL E G H	4340	7197	ORPHA:2073	Narcolepsy type 1	HP:0040281 - Very frequent	1
HP:0002360	HP:0002360	Sleep disturbance	0	MRPS34 CL E G H	65993	16618	OMIM:617664	Combined oxidative phosphorylation deficiency 32		1
HP:0002360	HP:0002360	Sleep disturbance	0	MTRR CL E G H	4552	7473	ORPHA:2169	Methylcobalamin deficiency type cblE		88
HP:0002360	HP:0002360	Sleep disturbance	0	MUSK CL E G H	4593	7525	ORPHA:994	Fetal akinesia deformation sequence		72
HP:0002360	HP:0002360	Sleep disturbance	0	MYL2 CL E G H	4633	7583	ORPHA:2020	Congenital fiber-type disproportion myopathy	HP:0040283 - Occasional	131
HP:0002360	HP:0002360	Sleep disturbance	0	MYO9A CL E G H	4649	7608	ORPHA:98914	Presynaptic congenital myasthenic syndromes
HP:0002360	HP:0002360	Sleep disturbance	0	MYOD1 CL E G H	4654	7611	ORPHA:994	Fetal akinesia deformation sequence
HP:0002360	HP:0002360	Sleep disturbance	0	NAA10 CL E G H	8260	18704	ORPHA:276432	Ogden syndrome		23
HP:0002360	HP:0002360	Sleep disturbance	0	NACC1 CL E G H	112939	20967	OMIM:617393	Neurodevelopmental disorder with epilepsy, cataracts, feeding difficulties, and delayed brain myelination		1
HP:0002360	HP:0002360	Sleep disturbance	0	NACC1 CL E G H	112939	20967	ORPHA:500545	Severe neurodevelopmental disorder with feeding difficulties-stereotypic hand movement-bilateral cataract	HP:0040282 - Frequent	1
HP:0002360	HP:0002360	Sleep disturbance	0	NADK2 CL E G H	133686	26404	ORPHA:431361	Progressive encephalopathy with leukodystrophy due to DECR deficiency		14
HP:0002360	HP:0002360	Sleep disturbance	0	NAGLU CL E G H	4669	7632	OMIM:252920	Mucopolysaccharidosis type IIIB	.	72
HP:0002360	HP:0002360	Sleep disturbance	0	NAGS CL E G H	162417	17996	ORPHA:927	Hyperammonemia due to N-acetylglutamate synthase deficiency		36
HP:0002360	HP:0002360	Sleep disturbance	0	NALCN CL E G H	259232	19082	ORPHA:371364	Hypotonia-speech impairment-severe cognitive delay syndrome	HP:0040283 - Occasional	48
HP:0002360	HP:0002360	Sleep disturbance	0	NCF1 CL E G H	653361	7660	ORPHA:904	Williams syndrome		13
HP:0002360	HP:0002360	Sleep disturbance	0	NDN CL E G H	4692	7675	ORPHA:98754	Prader-Willi syndrome due to maternal uniparental disomy of chromosome 15	HP:0040283 - Occasional
HP:0002360	HP:0002360	Sleep disturbance	0	NDN CL E G H	4692	7675	ORPHA:177901	Prader-Willi syndrome due to paternal deletion of 15q11q13 type 1	HP:0040282 - Frequent
HP:0002360	HP:0002360	Sleep disturbance	0	NDN CL E G H	4692	7675	ORPHA:177904	Prader-Willi syndrome due to paternal deletion of 15q11q13 type 2	HP:0040282 - Frequent
HP:0002360	HP:0002360	Sleep disturbance	0	NDP CL E G H	4693	7678	ORPHA:649	Norrie disease	HP:0040283 - Occasional	39
HP:0002360	HP:0002360	Sleep disturbance	0	NDST1 CL E G H	3340	7680	OMIM:616116	Mental retardation, autosomal recessive 46	.	27
HP:0002360	HP:0002360	Sleep disturbance	0	NEFH CL E G H	4744	7737	OMIM:105400	Amyotrophic lateral sclerosis 1		24
HP:0002360	HP:0002360	Sleep disturbance	0	NEFL CL E G H	4747	7739	ORPHA:101085	Charcot-Marie-Tooth disease type 1F		118
HP:0002360	HP:0002360	Sleep disturbance	0	NEUROD2 CL E G H	4761	7763	ORPHA:1934	Early infantile epileptic encephalopathy	HP:0040282 - Frequent
HP:0002360	HP:0002360	Sleep disturbance	0	NF1 CL E G H	4763	7765	ORPHA:97685	17q11 microdeletion syndrome	HP:0040282 - Frequent	1952
HP:0002360	HP:0002360	Sleep disturbance	0	NF2 CL E G H	4771	7773	ORPHA:2495	Meningioma		220
HP:0002360	HP:0002360	Sleep disturbance	0	NFIX CL E G H	4784	7788	OMIM:602535	Marshall-Smith syndrome		40
HP:0002360	HP:0002360	Sleep disturbance	0	NGLY1 CL E G H	55768	17646	ORPHA:404454	Alacrimia-choreoathetosis-liver dysfunction syndrome		32
HP:0002360	HP:0002360	Sleep disturbance	0	NGLY1 CL E G H	55768	17646	OMIM:615273	Congenital disorder of deglycosylation		32
HP:0002360	HP:0002360	Sleep disturbance	0	NHLRC1 CL E G H	378884	21576	ORPHA:501	Lafora disease	HP:0040283 - Occasional	77
HP:0002360	HP:0002360	Sleep disturbance	0	NIPBL CL E G H	25836	28862	ORPHA:199	Cornelia de Lange syndrome	HP:0040282 - Frequent	494
HP:0002360	HP:0002360	Sleep disturbance	0	NKX2-1 CL E G H	7080	11825	ORPHA:95713	Athyreosis		51
HP:0002360	HP:0002360	Sleep disturbance	0	NKX2-1 CL E G H	7080	11825	ORPHA:209905	Brain-lung-thyroid syndrome	HP:0040284 - Very rare	51
HP:0002360	HP:0002360	Sleep disturbance	0	NKX2-1 CL E G H	7080	11825	OMIM:610978	Choreoathetosis, hypothyroidism, and neonatal respiratory distress	HP:0040283 - Occasional	51
HP:0002360	HP:0002360	Sleep disturbance	0	NKX2-5 CL E G H	1482	2488	ORPHA:95713	Athyreosis		90
HP:0002360	HP:0002360	Sleep disturbance	0	NKX2-5 CL E G H	1482	2488	ORPHA:95712	Thyroid ectopia		90
HP:0002360	HP:0002360	Sleep disturbance	0	NODAL CL E G H	4838	7865	ORPHA:93925	Alobar holoprosencephaly		45
HP:0002360	HP:0002360	Sleep disturbance	0	NODAL CL E G H	4838	7865	ORPHA:93924	Lobar holoprosencephaly		45
HP:0002360	HP:0002360	Sleep disturbance	0	NODAL CL E G H	4838	7865	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		45
HP:0002360	HP:0002360	Sleep disturbance	0	NODAL CL E G H	4838	7865	ORPHA:220386	Semilobar holoprosencephaly		45
HP:0002360	HP:0002360	Sleep disturbance	0	NONO CL E G H	4841	7871	ORPHA:466791	Macrocephaly-intellectual disability-left ventricular non compaction syndrome		10
HP:0002360	HP:0002360	Sleep disturbance	0	NPAP1 CL E G H	23742	1190	OMIM:176270	Prader-Willi syndrome		1
HP:0002360	HP:0002360	Sleep disturbance	0	NR1H4 CL E G H	9971	7967	ORPHA:69665	Intrahepatic cholestasis of pregnancy		14
HP:0002360	HP:0002360	Sleep disturbance	0	NR4A2 CL E G H	4929	7981	ORPHA:98808	Autosomal dominant dopa-responsive dystonia	HP:0040282 - Frequent	27
HP:0002360	HP:0002360	Sleep disturbance	0	NR4A2 CL E G H	4929	7981	OMIM:168600	Parkinson disease, late-onset	.	27
HP:0002360	HP:0002360	Sleep disturbance	0	NSDHL CL E G H	50814	13398	OMIM:300831	Ck syndrome	.	34
HP:0002360	HP:0002360	Sleep disturbance	0	NSDHL CL E G H	50814	13398	ORPHA:251383	CK syndrome	HP:0040281 - Very frequent	34
HP:0002360	HP:0002360	Sleep disturbance	0	NTNG1 CL E G H	22854	23319	ORPHA:3095	Atypical Rett syndrome	HP:0040281 - Very frequent	1
HP:0002360	HP:0002360	Sleep disturbance	0	NUP88 CL E G H	4927	8067	ORPHA:994	Fetal akinesia deformation sequence
HP:0002360	HP:0002360	Sleep disturbance	0	OCA2 CL E G H	4948	8101	ORPHA:98754	Prader-Willi syndrome due to maternal uniparental disomy of chromosome 15	HP:0040283 - Occasional	121
HP:0002360	HP:0002360	Sleep disturbance	0	OCA2 CL E G H	4948	8101	ORPHA:177901	Prader-Willi syndrome due to paternal deletion of 15q11q13 type 1	HP:0040282 - Frequent	121
HP:0002360	HP:0002360	Sleep disturbance	0	OCA2 CL E G H	4948	8101	ORPHA:177904	Prader-Willi syndrome due to paternal deletion of 15q11q13 type 2	HP:0040282 - Frequent	121
HP:0002360	HP:0002360	Sleep disturbance	0	OTX2 CL E G H	5015	8522	ORPHA:3157	Septo-optic dysplasia spectrum	HP:0040283 - Occasional	41
HP:0002360	HP:0002360	Sleep disturbance	0	P2RY11 CL E G H	5032	8540	ORPHA:2073	Narcolepsy type 1	HP:0040281 - Very frequent	2
HP:0002360	HP:0002360	Sleep disturbance	0	P4HTM CL E G H	54681	28858	OMIM:618493	Hypotonia, hypoventilation, impaired intellectual development, dysautonomia, epilepsy, and eye abnormalities
HP:0002360	HP:0002360	Sleep disturbance	0	PARK7 CL E G H	11315	16369	ORPHA:2828	Young-onset Parkinson disease		23
HP:0002360	HP:0002360	Sleep disturbance	0	PAX8 CL E G H	7849	8622	ORPHA:95713	Athyreosis		63
HP:0002360	HP:0002360	Sleep disturbance	0	PAX8 CL E G H	7849	8622	ORPHA:95712	Thyroid ectopia		63
HP:0002360	HP:0002360	Sleep disturbance	0	PCGF2 CL E G H	7703	12929	OMIM:618371	Turnpenny-Fry syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	PDE2A CL E G H	5138	8777	OMIM:619150	INTELLECTUAL DEVELOPMENTAL DISORDER WITH PAROXYSMAL DYSKINESIA OR SEIZURES; IDDPADS
HP:0002360	HP:0002360	Sleep disturbance	0	PDGFB CL E G H	5155	8800	ORPHA:2495	Meningioma		9
HP:0002360	HP:0002360	Sleep disturbance	0	PER2 CL E G H	8864	8846	OMIM:604348	Advanced sleep phase syndrome, familial, 1		2
HP:0002360	HP:0002360	Sleep disturbance	0	PER3 CL E G H	8863	8847	OMIM:616882	Advanced sleep phase syndrome, familial, 3		3
HP:0002360	HP:0002360	Sleep disturbance	0	PHIP CL E G H	55023	15673	ORPHA:589905	PHIP-related behavioral problems-intellectual disability-obesity-dysmorphic features syndrome		11
HP:0002360	HP:0002360	Sleep disturbance	0	PHKA2 CL E G H	5256	8926	ORPHA:264580	Glycogen storage disease due to liver phosphorylase kinase deficiency	HP:0040283 - Occasional	54
HP:0002360	HP:0002360	Sleep disturbance	0	PHKG2 CL E G H	5261	8931	ORPHA:264580	Glycogen storage disease due to liver phosphorylase kinase deficiency	HP:0040283 - Occasional	48
HP:0002360	HP:0002360	Sleep disturbance	0	PHOX2B CL E G H	8929	9143	ORPHA:99803	Haddad syndrome		86
HP:0002360	HP:0002360	Sleep disturbance	0	PIDD1 CL E G H	55367	16491	OMIM:619827	INTELLECTUAL DEVELOPMENTAL DISORDER, AUTOSOMAL RECESSIVE 75, WITH NEUROPSYCHIATRIC FEATURES AND VARIANT LISSENCEPHALY; MRT75
HP:0002360	HP:0002360	Sleep disturbance	0	PIGP CL E G H	51227	3046	ORPHA:1934	Early infantile epileptic encephalopathy	HP:0040282 - Frequent	2
HP:0002360	HP:0002360	Sleep disturbance	0	PIGQ CL E G H	9091	14135	ORPHA:1934	Early infantile epileptic encephalopathy	HP:0040282 - Frequent	3
HP:0002360	HP:0002360	Sleep disturbance	0	PIGT CL E G H	51604	14938	ORPHA:369837	Intellectual disability-seizures-hypophosphatasia-ophthalmic-skeletal anomalies syndrome		12
HP:0002360	HP:0002360	Sleep disturbance	0	PIK3CA CL E G H	5290	8975	ORPHA:2495	Meningioma		162
HP:0002360	HP:0002360	Sleep disturbance	0	PINK1 CL E G H	65018	14581	ORPHA:2828	Young-onset Parkinson disease		55
HP:0002360	HP:0002360	Sleep disturbance	0	PLCB4 CL E G H	5332	9059	ORPHA:137888	Auriculocondylar syndrome		82
HP:0002360	HP:0002360	Sleep disturbance	0	PLCB4 CL E G H	5332	9059	OMIM:614669	Auriculocondylar syndrome 2		82
HP:0002360	HP:0002360	Sleep disturbance	0	PLCH1 CL E G H	23007	29185	ORPHA:93925	Alobar holoprosencephaly
HP:0002360	HP:0002360	Sleep disturbance	0	PNKP CL E G H	11284	9154	ORPHA:1934	Early infantile epileptic encephalopathy	HP:0040282 - Frequent	244
HP:0002360	HP:0002360	Sleep disturbance	0	PODXL CL E G H	5420	9171	ORPHA:2828	Young-onset Parkinson disease		6
HP:0002360	HP:0002360	Sleep disturbance	0	POGZ CL E G H	23126	18801	OMIM:616364	White-Sutton syndrome		35
HP:0002360	HP:0002360	Sleep disturbance	0	POGZ CL E G H	23126	18801	ORPHA:468678	White-Sutton syndrome	HP:0040282 - Frequent	35
HP:0002360	HP:0002360	Sleep disturbance	0	POLR2A CL E G H	5430	9187	OMIM:618603	NEURODEVELOPMENTAL DISORDER WITH HYPOTONIA AND VARIABLE INTELLECTUAL AND BEHAVIORAL ABNORMALITIES; NEDHIB
HP:0002360	HP:0002360	Sleep disturbance	0	POMT1 CL E G H	10585	9202	OMIM:236670	Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 1		213
HP:0002360	HP:0002360	Sleep disturbance	0	POMT2 CL E G H	29954	19743	OMIM:236670	Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 1		221
HP:0002360	HP:0002360	Sleep disturbance	0	POU2AF1 CL E G H	5450	9211	ORPHA:186	Primary biliary cholangitis	HP:0040283 - Occasional
HP:0002360	HP:0002360	Sleep disturbance	0	POU3F3 CL E G H	5455	9216	OMIM:618604	SNIJDERS BLOK-FISHER SYNDROME; SNIBFIS
HP:0002360	HP:0002360	Sleep disturbance	0	PPT1 CL E G H	5538	9325	OMIM:256730	Ceroid lipofuscinosis, neuronal, 1	.	172
HP:0002360	HP:0002360	Sleep disturbance	0	PRKAR1B CL E G H	5575	9390	OMIM:619680	MARBACH-SCHAAF NEURODEVELOPMENTAL SYNDROME; MASNS		2
HP:0002360	HP:0002360	Sleep disturbance	0	PRKN CL E G H	5071	8607	ORPHA:2828	Young-onset Parkinson disease		138
HP:0002360	HP:0002360	Sleep disturbance	0	PRMT7 CL E G H	54496	25557	ORPHA:464288	Short stature-brachydactyly-obesity-global developmental delay syndrome		6
HP:0002360	HP:0002360	Sleep disturbance	0	PRNP CL E G H	5621	9449	ORPHA:280397	Familial Alzheimer-like prion disease	HP:0040281 - Very frequent	69
HP:0002360	HP:0002360	Sleep disturbance	0	PRNP CL E G H	5621	9449	OMIM:600072	Fatal familial insomnia		69
HP:0002360	HP:0002360	Sleep disturbance	0	PRNP CL E G H	5621	9449	ORPHA:356	Gerstmann-Straussler-Scheinker syndrome	HP:0040282 - Frequent	69
HP:0002360	HP:0002360	Sleep disturbance	0	PRNP CL E G H	5621	9449	ORPHA:282166	Inherited Creutzfeldt-Jakob disease		69
HP:0002360	HP:0002360	Sleep disturbance	0	PROKR2 CL E G H	128674	15836	ORPHA:3157	Septo-optic dysplasia spectrum	HP:0040283 - Occasional	34
HP:0002360	HP:0002360	Sleep disturbance	0	PRPH CL E G H	5630	9461	OMIM:105400	Amyotrophic lateral sclerosis 1		25
HP:0002360	HP:0002360	Sleep disturbance	0	PRPS1 CL E G H	5631	9462	ORPHA:99014	X-linked Charcot-Marie-Tooth disease type 5		49
HP:0002360	HP:0002360	Sleep disturbance	0	PRPS1 CL E G H	5631	9462	ORPHA:423479	X-linked intellectual disability-limb spasticity-retinal dystrophy-diabetes insipidus syndrome		49
HP:0002360	HP:0002360	Sleep disturbance	0	PRR12 CL E G H	57479	29217	OMIM:619539	NEUROOCULAR SYNDROME; NOC		1
HP:0002360	HP:0002360	Sleep disturbance	0	PSEN2 CL E G H	5664	9509	OMIM:606889	Alzheimer disease 4		59
HP:0002360	HP:0002360	Sleep disturbance	0	PTCH1 CL E G H	5727	9585	ORPHA:93925	Alobar holoprosencephaly		665
HP:0002360	HP:0002360	Sleep disturbance	0	PTCH1 CL E G H	5727	9585	ORPHA:93924	Lobar holoprosencephaly		665
HP:0002360	HP:0002360	Sleep disturbance	0	PTCH1 CL E G H	5727	9585	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		665
HP:0002360	HP:0002360	Sleep disturbance	0	PTCH1 CL E G H	5727	9585	ORPHA:220386	Semilobar holoprosencephaly		665
HP:0002360	HP:0002360	Sleep disturbance	0	PTS CL E G H	5805	9689	OMIM:261640	Hyperphenylalaninemia, BH4-deficient, A		19
HP:0002360	HP:0002360	Sleep disturbance	0	PUF60 CL E G H	22827	17042	ORPHA:508498	Intellectual disability-cardiac anomalies-short stature-joint laxity syndrome	HP:0040283 - Occasional	19
HP:0002360	HP:0002360	Sleep disturbance	0	PWAR1 CL E G H	145624	30089	OMIM:176270	Prader-Willi syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	PWRN1 CL E G H	791114	33235	OMIM:176270	Prader-Willi syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	PYGL CL E G H	5836	9725	ORPHA:369	Glycogen storage disease due to liver glycogen phosphorylase deficiency	HP:0040283 - Occasional	71
HP:0002360	HP:0002360	Sleep disturbance	0	RAC1 CL E G H	5879	9801	OMIM:617751	Mental retardation, autosomal dominant 48		3
HP:0002360	HP:0002360	Sleep disturbance	0	RAD21 CL E G H	5885	9811	ORPHA:199	Cornelia de Lange syndrome	HP:0040282 - Frequent	25
HP:0002360	HP:0002360	Sleep disturbance	0	RAI1 CL E G H	10743	9834	ORPHA:1713	17p11.2 microduplication syndrome		150
HP:0002360	HP:0002360	Sleep disturbance	0	RAI1 CL E G H	10743	9834	ORPHA:477817	PMP22-RAI1 contiguous gene duplication syndrome	HP:0040282 - Frequent	150
HP:0002360	HP:0002360	Sleep disturbance	0	RAI1 CL E G H	10743	9834	OMIM:182290	Smith-Magenis syndrome		150
HP:0002360	HP:0002360	Sleep disturbance	0	RAI1 CL E G H	10743	9834	ORPHA:819	Smith-Magenis syndrome	HP:0040281 - Very frequent	150
HP:0002360	HP:0002360	Sleep disturbance	0	RAPSN CL E G H	5913	9863	ORPHA:994	Fetal akinesia deformation sequence		73
HP:0002360	HP:0002360	Sleep disturbance	0	RERE CL E G H	473	9965	OMIM:616975	Neurodevelopmental disorder with or without anomalies of the brain, eye, or heart		16
HP:0002360	HP:0002360	Sleep disturbance	0	RET CL E G H	5979	9967	ORPHA:99803	Haddad syndrome		572
HP:0002360	HP:0002360	Sleep disturbance	0	RFC1 CL E G H	5981	9969	OMIM:614575	Cerebellar ataxia, neuropathy, and vestibular areflexia syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	RFC2 CL E G H	5982	9970	ORPHA:904	Williams syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	RIC1 CL E G H	57589	17686	OMIM:618761	CATIFA SYNDROME; CATIFA
HP:0002360	HP:0002360	Sleep disturbance	0	RNU7-1 CL E G H	100147744	34033	OMIM:619487	AICARDI-GOUTIERES SYNDROME 9; AGS9
HP:0002360	HP:0002360	Sleep disturbance	0	RPS6KA3 CL E G H	6197	10432	ORPHA:192	Coffin-Lowry syndrome		65
HP:0002360	HP:0002360	Sleep disturbance	0	RTTN CL E G H	25914	18654	ORPHA:468631	Microcephalic cortical malformations-short stature due to RTTN deficiency	HP:0040283 - Occasional	113
HP:0002360	HP:0002360	Sleep disturbance	0	RUNX2 CL E G H	860	10472	ORPHA:1452	Cleidocranial dysplasia		90
HP:0002360	HP:0002360	Sleep disturbance	0	SARDH CL E G H	1757	10536	ORPHA:3129	Sarcosinemia	HP:0040283 - Occasional	4
HP:0002360	HP:0002360	Sleep disturbance	0	SATB1 CL E G H	6304	10541	OMIM:619228	DEVELOPMENTAL DELAY WITH DYSMORPHIC FACIES AND DENTAL ANOMALIES; DEFDA
HP:0002360	HP:0002360	Sleep disturbance	0	SATB1 CL E G H	6304	10541	OMIM:619229	KOHLSCHUTTER-TONZ SYNDROME-LIKE; KTZSL
HP:0002360	HP:0002360	Sleep disturbance	0	SATB2 CL E G H	23314	21637	ORPHA:251019	2q32q33 microdeletion syndrome	HP:0040283 - Occasional	34
HP:0002360	HP:0002360	Sleep disturbance	0	SATB2 CL E G H	23314	21637	OMIM:612313	Glass syndrome		34
HP:0002360	HP:0002360	Sleep disturbance	0	SATB2 CL E G H	23314	21637	ORPHA:251028	SATB2-associated syndrome due to a chromosomal rearrangement		34
HP:0002360	HP:0002360	Sleep disturbance	0	SATB2 CL E G H	23314	21637	ORPHA:576283	SATB2-associated syndrome due to a pathogenic variant	HP:0040282 - Frequent	34
HP:0002360	HP:0002360	Sleep disturbance	0	SCN1B CL E G H	6324	10586	ORPHA:1934	Early infantile epileptic encephalopathy	HP:0040282 - Frequent	126
HP:0002360	HP:0002360	Sleep disturbance	0	SCN2A CL E G H	6326	10588	ORPHA:1934	Early infantile epileptic encephalopathy	HP:0040282 - Frequent	427
HP:0002360	HP:0002360	Sleep disturbance	0	SELENON CL E G H	57190	15999	ORPHA:2020	Congenital fiber-type disproportion myopathy	HP:0040283 - Occasional	144
HP:0002360	HP:0002360	Sleep disturbance	0	SEPSECS CL E G H	51091	30605	ORPHA:2524	Pontocerebellar hypoplasia type 2	HP:0040281 - Very frequent	66
HP:0002360	HP:0002360	Sleep disturbance	0	SEPSECS CL E G H	51091	30605	OMIM:613811	Pontocerebellar hypoplasia, type 2D	.	66
HP:0002360	HP:0002360	Sleep disturbance	0	SEPTIN9 CL E G H	10801	7323	ORPHA:2901	Neuralgic amyotrophy	HP:0040283 - Occasional
HP:0002360	HP:0002360	Sleep disturbance	0	SETBP1 CL E G H	26040	15573	OMIM:616078	Mental retardation, autosomal dominant 29		143
HP:0002360	HP:0002360	Sleep disturbance	0	SETD1A CL E G H	9739	29010	OMIM:619056	NEURODEVELOPMENTAL DISORDER WITH SPEECH IMPAIRMENT AND DYSMORPHIC FACIES; NEDSID		6
HP:0002360	HP:0002360	Sleep disturbance	0	SETD5 CL E G H	55209	25566	ORPHA:404440	Intellectual disability-facial dysmorphism syndrome due to SETD5 haploinsufficiency	HP:0040283 - Occasional	43
HP:0002360	HP:0002360	Sleep disturbance	0	SGSH CL E G H	6448	10818	OMIM:252900	Mucopolysaccharidosis type IIIA	.	97
HP:0002360	HP:0002360	Sleep disturbance	0	SH3BP2 CL E G H	6452	10825	ORPHA:184	Cherubism		177
HP:0002360	HP:0002360	Sleep disturbance	0	SHANK3 CL E G H	85358	14294	ORPHA:48652	Monosomy 22q13.3	HP:0040282 - Frequent	53
HP:0002360	HP:0002360	Sleep disturbance	0	SHANK3 CL E G H	85358	14294	OMIM:606232	Phelan-Mcdermid syndrome		53
HP:0002360	HP:0002360	Sleep disturbance	0	SHH CL E G H	6469	10848	ORPHA:93925	Alobar holoprosencephaly		67
HP:0002360	HP:0002360	Sleep disturbance	0	SHH CL E G H	6469	10848	ORPHA:93924	Lobar holoprosencephaly		67
HP:0002360	HP:0002360	Sleep disturbance	0	SHH CL E G H	6469	10848	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		67
HP:0002360	HP:0002360	Sleep disturbance	0	SHH CL E G H	6469	10848	ORPHA:220386	Semilobar holoprosencephaly		67
HP:0002360	HP:0002360	Sleep disturbance	0	SIK1 CL E G H	150094	11142	ORPHA:1934	Early infantile epileptic encephalopathy	HP:0040282 - Frequent	11
HP:0002360	HP:0002360	Sleep disturbance	0	SIM1 CL E G H	6492	10882	ORPHA:398079	SIM1-related Prader-Willi-like syndrome		40
HP:0002360	HP:0002360	Sleep disturbance	0	SIN3A CL E G H	25942	19353	OMIM:613406	Witteveen-Kolk syndrome		9
HP:0002360	HP:0002360	Sleep disturbance	0	SIX3 CL E G H	6496	10889	ORPHA:93925	Alobar holoprosencephaly		32
HP:0002360	HP:0002360	Sleep disturbance	0	SIX3 CL E G H	6496	10889	ORPHA:93924	Lobar holoprosencephaly		32
HP:0002360	HP:0002360	Sleep disturbance	0	SIX3 CL E G H	6496	10889	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		32
HP:0002360	HP:0002360	Sleep disturbance	0	SIX3 CL E G H	6496	10889	ORPHA:220386	Semilobar holoprosencephaly		32
HP:0002360	HP:0002360	Sleep disturbance	0	SKI CL E G H	6497	10896	OMIM:182212	Shprintzen-Goldberg craniosynostosis syndrome		150
HP:0002360	HP:0002360	Sleep disturbance	0	SLC12A3 CL E G H	6559	10912	ORPHA:358	Gitelman syndrome		145
HP:0002360	HP:0002360	Sleep disturbance	0	SLC18A2 CL E G H	6571	10935	ORPHA:352649	Brain dopamine-serotonin vesicular transport disease	HP:0040281 - Very frequent	2
HP:0002360	HP:0002360	Sleep disturbance	0	SLC18A2 CL E G H	6571	10935	OMIM:618049	Parkinsonism-Dystonia, infantile, 2		2
HP:0002360	HP:0002360	Sleep disturbance	0	SLC18A3 CL E G H	6572	10936	ORPHA:994	Fetal akinesia deformation sequence		2
HP:0002360	HP:0002360	Sleep disturbance	0	SLC18A3 CL E G H	6572	10936	ORPHA:98914	Presynaptic congenital myasthenic syndromes		2
HP:0002360	HP:0002360	Sleep disturbance	0	SLC22A5 CL E G H	6584	10969	OMIM:212140	Carnitine deficiency, systemic primary		207
HP:0002360	HP:0002360	Sleep disturbance	0	SLC25A1 CL E G H	6576	10979	ORPHA:98914	Presynaptic congenital myasthenic syndromes		28
HP:0002360	HP:0002360	Sleep disturbance	0	SLC25A13 CL E G H	10165	10983	ORPHA:247585	Citrullinemia type II	HP:0040282 - Frequent	82
HP:0002360	HP:0002360	Sleep disturbance	0	SLC25A22 CL E G H	79751	19954	ORPHA:1934	Early infantile epileptic encephalopathy	HP:0040282 - Frequent	166
HP:0002360	HP:0002360	Sleep disturbance	0	SLC26A4 CL E G H	5172	8818	ORPHA:95713	Athyreosis		274
HP:0002360	HP:0002360	Sleep disturbance	0	SLC2A1 CL E G H	6513	11005	ORPHA:71277	Classic glucose transporter type 1 deficiency syndrome	HP:0040283 - Occasional	255
HP:0002360	HP:0002360	Sleep disturbance	0	SLC2A1 CL E G H	6513	11005	OMIM:606777	Glut1 deficiency syndrome 1	.	255
HP:0002360	HP:0002360	Sleep disturbance	0	SLC2A3 CL E G H	6515	11007	ORPHA:399	Huntington disease		1
HP:0002360	HP:0002360	Sleep disturbance	0	SLC35C1 CL E G H	55343	20197	ORPHA:99843	Leukocyte adhesion deficiency type II	HP:0040282 - Frequent	71
HP:0002360	HP:0002360	Sleep disturbance	0	SLC5A7 CL E G H	60482	14025	ORPHA:98914	Presynaptic congenital myasthenic syndromes		9
HP:0002360	HP:0002360	Sleep disturbance	0	SLC6A5 CL E G H	9152	11051	ORPHA:3197	Hereditary hyperekplexia	HP:0040282 - Frequent	81
HP:0002360	HP:0002360	Sleep disturbance	0	SLC9A6 CL E G H	10479	11079	OMIM:300243	Mental retardation, x-linked syndromic, Christianson type		93
HP:0002360	HP:0002360	Sleep disturbance	0	SLITRK1 CL E G H	114798	20297	OMIM:137580	Gilles de la tourette syndrome	.	58
HP:0002360	HP:0002360	Sleep disturbance	0	SMARCB1 CL E G H	6598	11103	ORPHA:2495	Meningioma		87
HP:0002360	HP:0002360	Sleep disturbance	0	SMARCC2 CL E G H	6601	11105	OMIM:618362	Coffin-Siris syndrome 8	.	1
HP:0002360	HP:0002360	Sleep disturbance	0	SMARCE1 CL E G H	6605	11109	ORPHA:2495	Meningioma		47
HP:0002360	HP:0002360	Sleep disturbance	0	SMC1A CL E G H	8243	11111	ORPHA:3095	Atypical Rett syndrome	HP:0040281 - Very frequent	135
HP:0002360	HP:0002360	Sleep disturbance	0	SMC1A CL E G H	8243	11111	ORPHA:199	Cornelia de Lange syndrome	HP:0040282 - Frequent	135
HP:0002360	HP:0002360	Sleep disturbance	0	SMC1A CL E G H	8243	11111	ORPHA:220386	Semilobar holoprosencephaly		135
HP:0002360	HP:0002360	Sleep disturbance	0	SMC3 CL E G H	9126	2468	ORPHA:199	Cornelia de Lange syndrome	HP:0040282 - Frequent	91
HP:0002360	HP:0002360	Sleep disturbance	0	SMO CL E G H	6608	11119	OMIM:241800	Hypothalamic hamartomascongenital hypothalamic hamartoma syndrome, included		22
HP:0002360	HP:0002360	Sleep disturbance	0	SMO CL E G H	6608	11119	ORPHA:2495	Meningioma		22
HP:0002360	HP:0002360	Sleep disturbance	0	SNAP25 CL E G H	6616	11132	ORPHA:98914	Presynaptic congenital myasthenic syndromes		2
HP:0002360	HP:0002360	Sleep disturbance	0	SNCA CL E G H	6622	11138	ORPHA:411602	Hereditary late-onset Parkinson disease	HP:0040283 - Occasional	65
HP:0002360	HP:0002360	Sleep disturbance	0	SNCA CL E G H	6622	11138	OMIM:168601	Parkinson disease 1, autosomal dominant	.	65
HP:0002360	HP:0002360	Sleep disturbance	0	SNCA CL E G H	6622	11138	ORPHA:171695	Parkinsonian-pyramidal syndrome	HP:0040282 - Frequent	65
HP:0002360	HP:0002360	Sleep disturbance	0	SNCA CL E G H	6622	11138	ORPHA:2828	Young-onset Parkinson disease		65
HP:0002360	HP:0002360	Sleep disturbance	0	SNCAIP CL E G H	9627	11139	OMIM:168600	Parkinson disease, late-onset	.	35
HP:0002360	HP:0002360	Sleep disturbance	0	SNORD115-1 CL E G H	338433	33020	OMIM:176270	Prader-Willi syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	SNORD116-1 CL E G H	100033413	33067	OMIM:176270	Prader-Willi syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	SNRPN CL E G H	6638	11164	OMIM:105830	Angelman syndrome		37
HP:0002360	HP:0002360	Sleep disturbance	0	SNRPN CL E G H	6638	11164	ORPHA:411515	Angelman syndrome due to imprinting defect in 15q11-q13		37
HP:0002360	HP:0002360	Sleep disturbance	0	SNRPN CL E G H	6638	11164	ORPHA:98754	Prader-Willi syndrome due to maternal uniparental disomy of chromosome 15	HP:0040283 - Occasional	37
HP:0002360	HP:0002360	Sleep disturbance	0	SNRPN CL E G H	6638	11164	ORPHA:177901	Prader-Willi syndrome due to paternal deletion of 15q11q13 type 1	HP:0040282 - Frequent	37
HP:0002360	HP:0002360	Sleep disturbance	0	SNRPN CL E G H	6638	11164	ORPHA:177904	Prader-Willi syndrome due to paternal deletion of 15q11q13 type 2	HP:0040282 - Frequent	37
HP:0002360	HP:0002360	Sleep disturbance	0	SOD1 CL E G H	6647	11179	OMIM:105400	Amyotrophic lateral sclerosis 1		53
HP:0002360	HP:0002360	Sleep disturbance	0	SOX2 CL E G H	6657	11195	ORPHA:3157	Septo-optic dysplasia spectrum	HP:0040283 - Occasional	33
HP:0002360	HP:0002360	Sleep disturbance	0	SOX3 CL E G H	6658	11199	ORPHA:3157	Septo-optic dysplasia spectrum	HP:0040283 - Occasional	24
HP:0002360	HP:0002360	Sleep disturbance	0	SPART CL E G H	23111	18514	ORPHA:101000	Autosomal recessive spastic paraplegia type 20	HP:0040283 - Occasional	66
HP:0002360	HP:0002360	Sleep disturbance	0	SPIB CL E G H	6689	11242	ORPHA:186	Primary biliary cholangitis	HP:0040283 - Occasional
HP:0002360	HP:0002360	Sleep disturbance	0	SPOP CL E G H	8405	11254	OMIM:618829	NABAIS SA-DE VRIES SYNDROME, TYPE 2; NSDVS2		16
HP:0002360	HP:0002360	Sleep disturbance	0	SPR CL E G H	6697	11257	ORPHA:70594	Dopa-responsive dystonia due to sepiapterin reductase deficiency	HP:0040282 - Frequent	28
HP:0002360	HP:0002360	Sleep disturbance	0	SPR CL E G H	6697	11257	OMIM:612716	Dystonia, dopa-responsive, due to sepiapterin reductase deficiency	.	28
HP:0002360	HP:0002360	Sleep disturbance	0	SPTBN1 CL E G H	6711	11275	OMIM:619475	DEVELOPMENTAL DELAY, IMPAIRED SPEECH, AND BEHAVIORAL ABNORMALITIES; DDISBA
HP:0002360	HP:0002360	Sleep disturbance	0	SRPX2 CL E G H	27286	30668	ORPHA:1945	Rolandic epilepsy		50
HP:0002360	HP:0002360	Sleep disturbance	0	STAG2 CL E G H	10735	11355	ORPHA:93925	Alobar holoprosencephaly		1
HP:0002360	HP:0002360	Sleep disturbance	0	STAG2 CL E G H	10735	11355	ORPHA:220386	Semilobar holoprosencephaly		1
HP:0002360	HP:0002360	Sleep disturbance	0	STAG2 CL E G H	10735	11355	ORPHA:521258	Xq25 microduplication syndrome	HP:0040282 - Frequent	1
HP:0002360	HP:0002360	Sleep disturbance	0	STIL CL E G H	6491	10879	ORPHA:93925	Alobar holoprosencephaly		99
HP:0002360	HP:0002360	Sleep disturbance	0	STIL CL E G H	6491	10879	ORPHA:93924	Lobar holoprosencephaly		99
HP:0002360	HP:0002360	Sleep disturbance	0	STIL CL E G H	6491	10879	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		99
HP:0002360	HP:0002360	Sleep disturbance	0	STIL CL E G H	6491	10879	ORPHA:220386	Semilobar holoprosencephaly		99
HP:0002360	HP:0002360	Sleep disturbance	0	STOX1 CL E G H	219736	23508	ORPHA:275555	Preeclampsia	HP:0040284 - Very rare	2
HP:0002360	HP:0002360	Sleep disturbance	0	STUB1 CL E G H	10273	11427	OMIM:618093	SPINOCEREBELLAR ATAXIA 48; SCA48		14
HP:0002360	HP:0002360	Sleep disturbance	0	STX1A CL E G H	6804	11433	ORPHA:904	Williams syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	SUCLG1 CL E G H	8802	11449	ORPHA:17	Fatal infantile lactic acidosis with methylmalonic aciduria	HP:0040283 - Occasional	60
HP:0002360	HP:0002360	Sleep disturbance	0	SUFU CL E G H	51684	16466	ORPHA:2495	Meningioma		124
HP:0002360	HP:0002360	Sleep disturbance	0	SUPT16H CL E G H	11198	11465	OMIM:619480	NEURODEVELOPMENTAL DISORDER WITH DYSMORPHIC FACIES AND THIN CORPUS CALLOSUM; NEDDFAC
HP:0002360	HP:0002360	Sleep disturbance	0	SYNGAP1 CL E G H	8831	11497	ORPHA:544254	SYNGAP1-related developmental and epileptic encephalopathy	HP:0040282 - Frequent	108
HP:0002360	HP:0002360	Sleep disturbance	0	SYNJ1 CL E G H	8867	11503	ORPHA:2828	Young-onset Parkinson disease		9
HP:0002360	HP:0002360	Sleep disturbance	0	SYT1 CL E G H	6857	11509	OMIM:618218	Baker-Gordon syndrome		1
HP:0002360	HP:0002360	Sleep disturbance	0	SYT1 CL E G H	6857	11509	ORPHA:522077	Infantile hypotonia-oculomotor anomalies-hyperkinetic movements-developmental delay syndrome	HP:0040282 - Frequent	1
HP:0002360	HP:0002360	Sleep disturbance	0	SYT2 CL E G H	127833	11510	ORPHA:98914	Presynaptic congenital myasthenic syndromes		4
HP:0002360	HP:0002360	Sleep disturbance	0	TAF1 CL E G H	6872	11535	OMIM:300966	MENTAL RETARDATION, X-LINKED, SYNDROMIC 33; MRXS33		21
HP:0002360	HP:0002360	Sleep disturbance	0	TANC2 CL E G H	26115	30212	OMIM:618906	INTELLECTUAL DEVELOPMENTAL DISORDER WITH AUTISTIC FEATURES AND LANGUAGE DELAY, WITH OR WITHOUT SEIZURES; IDDALDS
HP:0002360	HP:0002360	Sleep disturbance	0	TBC1D20 CL E G H	128637	16133	OMIM:615663	Warburg micro syndrome 4		15
HP:0002360	HP:0002360	Sleep disturbance	0	TBC1D24 CL E G H	57465	29203	ORPHA:352596	Progressive myoclonic epilepsy with dystonia		271
HP:0002360	HP:0002360	Sleep disturbance	0	TBK1 CL E G H	29110	11584	ORPHA:1930	Herpes simplex virus encephalitis		20
HP:0002360	HP:0002360	Sleep disturbance	0	TBL2 CL E G H	26608	11586	ORPHA:904	Williams syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	TBP CL E G H	6908	11588	OMIM:168600	Parkinson disease, late-onset	.	7
HP:0002360	HP:0002360	Sleep disturbance	0	TCF20 CL E G H	6942	11631	OMIM:618430	Developmental delay with variable intellectual impairment and behavioral abnormalities	.	1
HP:0002360	HP:0002360	Sleep disturbance	0	TCF4 CL E G H	6925	11634	ORPHA:2896	Pitt-Hopkins syndrome	HP:0040281 - Very frequent	241
HP:0002360	HP:0002360	Sleep disturbance	0	TDGF1 CL E G H	6997	11701	ORPHA:93925	Alobar holoprosencephaly		1
HP:0002360	HP:0002360	Sleep disturbance	0	TDGF1 CL E G H	6997	11701	ORPHA:93924	Lobar holoprosencephaly		1
HP:0002360	HP:0002360	Sleep disturbance	0	TDGF1 CL E G H	6997	11701	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		1
HP:0002360	HP:0002360	Sleep disturbance	0	TDGF1 CL E G H	6997	11701	ORPHA:220386	Semilobar holoprosencephaly		1
HP:0002360	HP:0002360	Sleep disturbance	0	TDP2 CL E G H	51567	17768	OMIM:616949	Spinocerebellar ataxia, autosomal recessive 23		3
HP:0002360	HP:0002360	Sleep disturbance	0	TELO2 CL E G H	9894	29099	ORPHA:488642	TELO2-related intellectual disability-neurodevelopmental disorder		12
HP:0002360	HP:0002360	Sleep disturbance	0	TERT CL E G H	7015	11730	ORPHA:2495	Meningioma		238
HP:0002360	HP:0002360	Sleep disturbance	0	TERT CL E G H	7015	11730	OMIM:614742	PULMONARY FIBROSIS AND/OR BONE MARROW FAILURE, TELOMERE-RELATED, 1; PFBMFT1		238
HP:0002360	HP:0002360	Sleep disturbance	0	TFAP2B CL E G H	7021	11743	OMIM:169100	Char syndrome		104
HP:0002360	HP:0002360	Sleep disturbance	0	TFAP2B CL E G H	7021	11743	ORPHA:46627	Char syndrome	HP:0040283 - Occasional	104
HP:0002360	HP:0002360	Sleep disturbance	0	TFE3 CL E G H	7030	11752	OMIM:301066	INTELLECTUAL DEVELOPMENTAL DISORDER, X-LINKED, SYNDROMIC, WITH PIGMENTARY MOSAICISM AND COARSE FACIES; MRXSPF
HP:0002360	HP:0002360	Sleep disturbance	0	TGIF1 CL E G H	7050	11776	ORPHA:93925	Alobar holoprosencephaly		32
HP:0002360	HP:0002360	Sleep disturbance	0	TGIF1 CL E G H	7050	11776	ORPHA:93924	Lobar holoprosencephaly		32
HP:0002360	HP:0002360	Sleep disturbance	0	TGIF1 CL E G H	7050	11776	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		32
HP:0002360	HP:0002360	Sleep disturbance	0	TGIF1 CL E G H	7050	11776	ORPHA:220386	Semilobar holoprosencephaly		32
HP:0002360	HP:0002360	Sleep disturbance	0	TICAM1 CL E G H	148022	18348	ORPHA:1930	Herpes simplex virus encephalitis		6
HP:0002360	HP:0002360	Sleep disturbance	0	TIMELESS CL E G H	8914	11813	OMIM:620015
HP:0002360	HP:0002360	Sleep disturbance	0	TLR3 CL E G H	7098	11849	ORPHA:1930	Herpes simplex virus encephalitis		3
HP:0002360	HP:0002360	Sleep disturbance	0	TMEM270 CL E G H	135886	23018	ORPHA:904	Williams syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	TNFSF15 CL E G H	9966	11931	ORPHA:186	Primary biliary cholangitis	HP:0040283 - Occasional
HP:0002360	HP:0002360	Sleep disturbance	0	TNFSF4 CL E G H	7292	11934	ORPHA:2073	Narcolepsy type 1	HP:0040281 - Very frequent
HP:0002360	HP:0002360	Sleep disturbance	0	TNPO3 CL E G H	23534	17103	ORPHA:186	Primary biliary cholangitis	HP:0040283 - Occasional	71
HP:0002360	HP:0002360	Sleep disturbance	0	TNRC6B CL E G H	23112	29190	OMIM:619243	GLOBAL DEVELOPMENTAL DELAY WITH SPEECH AND BEHAVIORAL ABNORMALITIES; GDSBA
HP:0002360	HP:0002360	Sleep disturbance	0	TPM2 CL E G H	7169	12011	ORPHA:2020	Congenital fiber-type disproportion myopathy	HP:0040283 - Occasional	54
HP:0002360	HP:0002360	Sleep disturbance	0	TPM3 CL E G H	7170	12012	ORPHA:2020	Congenital fiber-type disproportion myopathy	HP:0040283 - Occasional	108
HP:0002360	HP:0002360	Sleep disturbance	0	TRAF3 CL E G H	7187	12033	ORPHA:1930	Herpes simplex virus encephalitis		2
HP:0002360	HP:0002360	Sleep disturbance	0	TRAF7 CL E G H	84231	20456	ORPHA:2495	Meningioma
HP:0002360	HP:0002360	Sleep disturbance	0	TRIM8 CL E G H	81603	15579	ORPHA:1934	Early infantile epileptic encephalopathy	HP:0040282 - Frequent	1
HP:0002360	HP:0002360	Sleep disturbance	0	TRIO CL E G H	7204	12303	ORPHA:476126	Micrognathia-recurrent infections-behavioral abnormalities-mild intellectual disability syndrome	HP:0040283 - Occasional	8
HP:0002360	HP:0002360	Sleep disturbance	0	TRNT CL E G H	4576	7499	OMIM:168600	Parkinson disease, late-onset	.
HP:0002360	HP:0002360	Sleep disturbance	0	TRPV4 CL E G H	59341	18083	OMIM:606071	Hereditary motor and sensory neuropathy, type IIC		214
HP:0002360	HP:0002360	Sleep disturbance	0	TSC1 CL E G H	7248	12362	ORPHA:805	Tuberous sclerosis complex	HP:0040282 - Frequent	1090
HP:0002360	HP:0002360	Sleep disturbance	0	TSC2 CL E G H	7249	12363	ORPHA:805	Tuberous sclerosis complex	HP:0040282 - Frequent	2738
HP:0002360	HP:0002360	Sleep disturbance	0	TSEN15 CL E G H	116461	16791	ORPHA:2524	Pontocerebellar hypoplasia type 2	HP:0040281 - Very frequent	3
HP:0002360	HP:0002360	Sleep disturbance	0	TSEN2 CL E G H	80746	28422	ORPHA:2524	Pontocerebellar hypoplasia type 2	HP:0040281 - Very frequent	84
HP:0002360	HP:0002360	Sleep disturbance	0	TSEN34 CL E G H	79042	15506	ORPHA:2524	Pontocerebellar hypoplasia type 2	HP:0040281 - Very frequent	57
HP:0002360	HP:0002360	Sleep disturbance	0	TSEN54 CL E G H	283989	27561	ORPHA:2524	Pontocerebellar hypoplasia type 2	HP:0040281 - Very frequent	102
HP:0002360	HP:0002360	Sleep disturbance	0	TSHR CL E G H	7253	12373	ORPHA:95713	Athyreosis		97
HP:0002360	HP:0002360	Sleep disturbance	0	TSHR CL E G H	7253	12373	ORPHA:99819	Familial gestational hyperthyroidism	HP:0040282 - Frequent	97
HP:0002360	HP:0002360	Sleep disturbance	0	TSHR CL E G H	7253	12373	ORPHA:424	Familial hyperthyroidism due to mutations in TSH receptor	HP:0040282 - Frequent	97
HP:0002360	HP:0002360	Sleep disturbance	0	TSPYL1 CL E G H	7259	12382	ORPHA:168593	Sudden infant death-dysgenesis of the testes syndrome		1
HP:0002360	HP:0002360	Sleep disturbance	0	TTC5 CL E G H	91875	19274	OMIM:619244	NEURODEVELOPMENTAL DISORDER WITH CEREBRAL ATROPHY AND VARIABLE FACIAL DYSMORPHISM; NEDCAFD
HP:0002360	HP:0002360	Sleep disturbance	0	TTI2 CL E G H	80185	26262	OMIM:615541	Mental retardation, autosomal recessive 39		11
HP:0002360	HP:0002360	Sleep disturbance	0	TTI2 CL E G H	80185	26262	ORPHA:391307	Severe intellectual disability-short stature-behavioral abnormalities-facial dysmorphism syndrome	HP:0040282 - Frequent	11
HP:0002360	HP:0002360	Sleep disturbance	0	TUBA1A CL E G H	7846	20766	ORPHA:994	Fetal akinesia deformation sequence		106
HP:0002360	HP:0002360	Sleep disturbance	0	TUBB3 CL E G H	10381	20772	ORPHA:300570	Cortical dysgenesis with pontocerebellar hypoplasia due to TUBB3 mutation		64
HP:0002360	HP:0002360	Sleep disturbance	0	TWIST1 CL E G H	7291	12428	ORPHA:794	Saethre-Chotzen syndrome		18
HP:0002360	HP:0002360	Sleep disturbance	0	TWNK CL E G H	56652	1160	OMIM:271245	Mitochondrial DNA depletion syndrome 7 (hepatocerebral type)		113
HP:0002360	HP:0002360	Sleep disturbance	0	UBE3A CL E G H	7337	12496	OMIM:105830	Angelman syndrome		278
HP:0002360	HP:0002360	Sleep disturbance	0	UBE3A CL E G H	7337	12496	ORPHA:411515	Angelman syndrome due to imprinting defect in 15q11-q13		278
HP:0002360	HP:0002360	Sleep disturbance	0	UCHL1 CL E G H	7345	12513	ORPHA:2828	Young-onset Parkinson disease		21
HP:0002360	HP:0002360	Sleep disturbance	0	UNC80 CL E G H	285175	26582	ORPHA:371364	Hypotonia-speech impairment-severe cognitive delay syndrome	HP:0040283 - Occasional	23
HP:0002360	HP:0002360	Sleep disturbance	0	UNC93B1 CL E G H	81622	13481	ORPHA:1930	Herpes simplex virus encephalitis		5
HP:0002360	HP:0002360	Sleep disturbance	0	USP7 CL E G H	7874	12630	ORPHA:500055	16p13.2 microdeletion syndrome	HP:0040283 - Occasional	2
HP:0002360	HP:0002360	Sleep disturbance	0	USP7 CL E G H	7874	12630	OMIM:616863	Chromosome 16p13.2 deletion syndrome		2
HP:0002360	HP:0002360	Sleep disturbance	0	VAMP1 CL E G H	6843	12642	ORPHA:98914	Presynaptic congenital myasthenic syndromes		2
HP:0002360	HP:0002360	Sleep disturbance	0	VPS13A CL E G H	23230	1908	ORPHA:2388	Choreoacanthocytosis	HP:0040284 - Very rare	130
HP:0002360	HP:0002360	Sleep disturbance	0	VPS13C CL E G H	54832	23594	ORPHA:2828	Young-onset Parkinson disease		8
HP:0002360	HP:0002360	Sleep disturbance	0	VPS35 CL E G H	55737	13487	ORPHA:411602	Hereditary late-onset Parkinson disease	HP:0040283 - Occasional	37
HP:0002360	HP:0002360	Sleep disturbance	0	VPS37D CL E G H	155382	18287	ORPHA:904	Williams syndrome
HP:0002360	HP:0002360	Sleep disturbance	0	VPS4A CL E G H	27183	13488	OMIM:619273	CIMDAG SYNDROME; CIMDAG		1
HP:0002360	HP:0002360	Sleep disturbance	0	VPS51 CL E G H	738	1172	OMIM:618606	PONTOCEREBELLAR HYPOPLASIA, TYPE 13; PCH13
HP:0002360	HP:0002360	Sleep disturbance	0	VRK1 CL E G H	7443	12718	OMIM:607596	Pontocerebellar hypoplasia type 1A		32
HP:0002360	HP:0002360	Sleep disturbance	0	WAC CL E G H	51322	17327	OMIM:616708	Desanto-Shinawi syndrome		20
HP:0002360	HP:0002360	Sleep disturbance	0	WAC CL E G H	51322	17327	ORPHA:284169	Facial dysmorphism-developmental delay-behavioral abnormalities syndrome due to 10p11.21p12.31 microdeletion	HP:0040282 - Frequent	20
HP:0002360	HP:0002360	Sleep disturbance	0	WAC CL E G H	51322	17327	ORPHA:466950	Facial dysmorphism-developmental delay-behavioral abnormalities syndrome due to WAC point mutation	HP:0040282 - Frequent	20
HP:0002360	HP:0002360	Sleep disturbance	0	WDR4 CL E G H	10785	12756	OMIM:618347	Galloway-Mowat syndrome 6	.
HP:0002360	HP:0002360	Sleep disturbance	0	WDR45 CL E G H	11152	28912	ORPHA:329284	Beta-propeller protein-associated neurodegeneration	HP:0040282 - Frequent	51
HP:0002360	HP:0002360	Sleep disturbance	0	WDR73 CL E G H	84942	25928	OMIM:251300	Galloway-mowat syndrome 1		14
HP:0002360	HP:0002360	Sleep disturbance	0	WFS1 CL E G H	7466	12762	ORPHA:3463	Wolfram syndrome	HP:0040283 - Occasional	389
HP:0002360	HP:0002360	Sleep disturbance	0	YY1 CL E G H	7528	12856	OMIM:617557	Gabriele-De vries syndrome		7
HP:0002360	HP:0002360	Sleep disturbance	0	YY1 CL E G H	7528	12856	ORPHA:97279	Insulinoma		7
HP:0002360	HP:0002360	Sleep disturbance	0	ZBTB7A CL E G H	51341	18078	OMIM:619769	MACROCEPHALY, NEURODEVELOPMENTAL DELAY, LYMPHOID HYPERPLASIA, AND PERSISTENT FETAL HEMOGLOBIN; MNDLFH
HP:0002360	HP:0002360	Sleep disturbance	0	ZEB2 CL E G H	9839	14881	ORPHA:261552	Mowat-Wilson syndrome due to a ZEB2 point mutation	HP:0040282 - Frequent	362
HP:0002360	HP:0002360	Sleep disturbance	0	ZEB2 CL E G H	9839	14881	ORPHA:261537	Mowat-Wilson syndrome due to monosomy 2q22	HP:0040282 - Frequent	362
HP:0002360	HP:0002360	Sleep disturbance	0	ZIC2 CL E G H	7546	12873	ORPHA:93925	Alobar holoprosencephaly		34
HP:0002360	HP:0002360	Sleep disturbance	0	ZIC2 CL E G H	7546	12873	ORPHA:93924	Lobar holoprosencephaly		34
HP:0002360	HP:0002360	Sleep disturbance	0	ZIC2 CL E G H	7546	12873	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		34
HP:0002360	HP:0002360	Sleep disturbance	0	ZIC2 CL E G H	7546	12873	ORPHA:220386	Semilobar holoprosencephaly		34
HP:0002360	HP:0002360	Sleep disturbance	0	ZMYM2 CL E G H	7750	12989	OMIM:619522	NEURODEVELOPMENTAL-CRANIOFACIAL SYNDROME WITH VARIABLE RENAL AND CARDIAC ABNORMALITIES; NECRC
HP:0002360	HP:0002360	Sleep disturbance	0	ZNF365 CL E G H	22891	18194	ORPHA:2073	Narcolepsy type 1	HP:0040281 - Very frequent	3
HP:0002360	HP:0002360	Sleep disturbance	0	ZNF365 CL E G H	22891	18194	ORPHA:83465	Narcolepsy type 2	HP:0040281 - Very frequent	3
HP:0002360	HP:0033063	Shortened sleep cycle	1	CL E G H
HP:0002360	HP:0100785	Insomnia	1	ABCB11 CL E G H	8647	42	ORPHA:69665	Intrahepatic cholestasis of pregnancy	HP:0040282 - Frequent	146
HP:0002360	HP:0100785	Insomnia	1	ABCB4 CL E G H	5244	45	ORPHA:69665	Intrahepatic cholestasis of pregnancy	HP:0040282 - Frequent	111
HP:0002360	HP:0010535	Sleep apnea	1	ABCC9 CL E G H	10060	60	OMIM:619719	INTELLECTUAL DISABILITY AND MYOPATHY SYNDROME; IDMYS		254
HP:0002360	HP:0001262	Excessive daytime somnolence	1	ACAT1 CL E G H	38	93	ORPHA:134	Beta-ketothiolase deficiency	HP:0040282 - Frequent	91
HP:0002360	HP:0010535	Sleep apnea	1	AFF4 CL E G H	27125	17869	OMIM:616368	CHOPS syndrome		6
HP:0002360	HP:0010535	Sleep apnea	1	AFF4 CL E G H	27125	17869	ORPHA:444077	Cognitive impairment-coarse facies-heart defects-obesity-pulmonary involvement-short stature-skeletal dysplasia syndrome	HP:0040283 - Occasional	6
HP:0002360	HP:0010535	Sleep apnea	1	AGRN CL E G H	375790	329	ORPHA:98914	Presynaptic congenital myasthenic syndromes		127
HP:0002360	HP:0025267	Snoring	1	AHDC1 CL E G H	27245	25230	ORPHA:412069	AHDC1-related intellectual disability-obstructive sleep apnea-mild dysmorphism syndrome	HP:0040283 - Occasional	36
HP:0002360	HP:0010535	Sleep apnea	1	AHDC1 CL E G H	27245	25230	ORPHA:412069	AHDC1-related intellectual disability-obstructive sleep apnea-mild dysmorphism syndrome		36
HP:0002360	HP:0025267	Snoring	1	AHDC1 CL E G H	27245	25230	OMIM:615829	Xia-Gibbs syndrome	.	36
HP:0002360	HP:0010535	Sleep apnea	1	AHDC1 CL E G H	27245	25230	OMIM:615829	Xia-Gibbs syndrome		36
HP:0002360	HP:0100786	Hypersomnia	1	AIP CL E G H	9049	358	ORPHA:963	Acromegaly	HP:0040283 - Occasional	95
HP:0002360	HP:0010535	Sleep apnea	1	AIP CL E G H	9049	358	ORPHA:963	Acromegaly	HP:0040282 - Frequent	95
HP:0002360	HP:0001262	Excessive daytime somnolence	1	AKT1 CL E G H	207	391	ORPHA:2495	Meningioma	HP:0040284 - Very rare	54
HP:0002360	HP:0006979	Sleep-wake cycle disturbance	1	APOE CL E G H	348	613	OMIM:606889	Alzheimer disease 4	.	39
HP:0002360	HP:0010535	Sleep apnea	1	ARCN1 CL E G H	372	649	OMIM:617164	Short stature, rhizomelic, with microcephaly, micrognathia, and developmental delay		3
HP:0002360	HP:0010535	Sleep apnea	1	ARL3 CL E G H	403	694	OMIM:618161	JOUBERT SYNDROME 35; JBTS35		1
HP:0002360	HP:0010535	Sleep apnea	1	ARSB CL E G H	411	714	OMIM:253200	Mucopolysaccharidosis, type VI		120
HP:0002360	HP:0010535	Sleep apnea	1	ASCL1 CL E G H	429	738	ORPHA:99803	Haddad syndrome		15
HP:0002360	HP:0001262	Excessive daytime somnolence	1	ASH1L CL E G H	55870	19088	OMIM:617796	Mental retardation, autosomal dominant 52		1
HP:0002360	HP:0010535	Sleep apnea	1	ASXL1 CL E G H	171023	18318	ORPHA:97297	Bohring-Opitz syndrome		145
HP:0002360	HP:0010535	Sleep apnea	1	ATN1 CL E G H	1822	3033	OMIM:618494	Congenital hypotonia, epilepsy, developmental delay, and digital anomalies		16
HP:0002360	HP:0006979	Sleep-wake cycle disturbance	1	ATP10A CL E G H	57194	13542	ORPHA:411515	Angelman syndrome due to imprinting defect in 15q11-q13	HP:0040283 - Occasional	4
HP:0002360	HP:0010535	Sleep apnea	1	ATP1A2 CL E G H	477	800	OMIM:619605	DEVELOPMENTAL AND EPILEPTIC ENCEPHALOPATHY 98; DEE98		239
HP:0002360	HP:0100785	Insomnia	1	ATP7B CL E G H	540	870	OMIM:277900	Wilson disease		315
HP:0002360	HP:0100785	Insomnia	1	ATP8B1 CL E G H	5205	3706	ORPHA:69665	Intrahepatic cholestasis of pregnancy	HP:0040282 - Frequent	144
HP:0002360	HP:0012452	Restless legs	1	ATXN7 CL E G H	6314	10560	ORPHA:94147	Spinocerebellar ataxia type 7	HP:0040282 - Frequent	8
HP:0002360	HP:0001262	Excessive daytime somnolence	1	BAP1 CL E G H	8314	950	ORPHA:2495	Meningioma	HP:0040284 - Very rare	184
HP:0002360	HP:0100785	Insomnia	1	BAZ1B CL E G H	9031	961	ORPHA:904	Williams syndrome	HP:0040282 - Frequent
HP:0002360	HP:0100785	Insomnia	1	BCL7B CL E G H	9275	1005	ORPHA:904	Williams syndrome	HP:0040282 - Frequent
HP:0002360	HP:0010535	Sleep apnea	1	BICD2 CL E G H	23299	17208	OMIM:615290	Spinal muscular atrophy, lower extremity-predominant, 2, autosomaldominant		46
HP:0002360	HP:0010535	Sleep apnea	1	BMP2 CL E G H	650	1069	OMIM:617877	Short stature, facial dysmorphism, and skeletal anomalies with or without cardiac anomalies		13
HP:0002360	HP:0001262	Excessive daytime somnolence	1	BRAF CL E G H	673	1097	ORPHA:54595	Craniopharyngioma	HP:0040282 - Frequent	276
HP:0002360	HP:0010535	Sleep apnea	1	BRAF CL E G H	673	1097	ORPHA:54595	Craniopharyngioma	HP:0040283 - Occasional	276
HP:0002360	HP:0100785	Insomnia	1	BUD23 CL E G H	114049	16405	ORPHA:904	Williams syndrome	HP:0040282 - Frequent
HP:0002360	HP:0010535	Sleep apnea	1	C2CD3 CL E G H	26005	24564	ORPHA:434179	Orofaciodigital syndrome type 14	HP:0040282 - Frequent	27
HP:0002360	HP:0010535	Sleep apnea	1	CA2 CL E G H	760	1373	ORPHA:2785	Osteopetrosis with renal tubular acidosis		29
HP:0002360	HP:0025234	Parasomnia	1	CABP4 CL E G H	57010	1386	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy		94
HP:0002360	HP:0010535	Sleep apnea	1	CACNA1C CL E G H	775	1390	OMIM:620029			572
HP:0002360	HP:0006979	Sleep-wake cycle disturbance	1	CAMK2A CL E G H	815	1460	OMIM:617798	Mental retardation, autosomal dominant 53		1
HP:0002360	HP:0010535	Sleep apnea	1	CCDC47 CL E G H	57003	24856	OMIM:618268	Trichohepatoneurodevelopmental syndrome
HP:0002360	HP:0010535	Sleep apnea	1	CDC42BPB CL E G H	9578	1738	OMIM:619841
HP:0002360	HP:0010535	Sleep apnea	1	CDK13 CL E G H	8621	1733	OMIM:617360	Congenital heart defects, dysmorphic facial features, and intellectual developmental disorder		8
HP:0002360	HP:0006979	Sleep-wake cycle disturbance	1	CDKL5 CL E G H	6792	11411	ORPHA:505652	CDKL5-deficiency disorder	HP:0040282 - Frequent	405
HP:0002360	HP:0006979	Sleep-wake cycle disturbance	1	CDON CL E G H	50937	17104	ORPHA:93925	Alobar holoprosencephaly	HP:0040282 - Frequent	200
HP:0002360	HP:0006979	Sleep-wake cycle disturbance	1	CDON CL E G H	50937	17104	ORPHA:93924	Lobar holoprosencephaly	HP:0040282 - Frequent	200
HP:0002360	HP:0006979	Sleep-wake cycle disturbance	1	CDON CL E G H	50937	17104	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly	HP:0040282 - Frequent	200
HP:0002360	HP:0006979	Sleep-wake cycle disturbance	1	CDON CL E G H	50937	17104	ORPHA:220386	Semilobar holoprosencephaly	HP:0040282 - Frequent	200
HP:0002360	HP:0010535	Sleep apnea	1	CEP57 CL E G H	9702	30794	OMIM:614114	Mosaic variegated aneuploidy syndrome 2		17
HP:0002360	HP:0010535	Sleep apnea	1	CHAMP1 CL E G H	283489	20311	OMIM:616579	Mental retardation, autosomal dominant 40		16
HP:0002360	HP:0010535	Sleep apnea	1	CHAT CL E G H	1103	1912	ORPHA:98914	Presynaptic congenital myasthenic syndromes		65
HP:0002360	HP:0006979	Sleep-wake cycle disturbance	1	CHD8 CL E G H	57680	20153	OMIM:615032	AUTISM, SUSCEPTIBILITY TO, 18; AUTS18		72
HP:0002360	HP:0025234	Parasomnia	1	CHRNA2 CL E G H	1135	1956	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy		188
HP:0002360	HP:0025234	Parasomnia	1	CHRNA4 CL E G H	1137	1958	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy		225
HP:0002360	HP:0025234	Parasomnia	1	CHRNB2 CL E G H	1141	1962	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy		88
HP:0002360	HP:0001262	Excessive daytime somnolence	1	CLCNKB CL E G H	1188	2027	ORPHA:358	Gitelman syndrome	HP:0040284 - Very rare	27
HP:0002360	HP:0100785	Insomnia	1	CLCNKB CL E G H	1188	2027	ORPHA:358	Gitelman syndrome	HP:0040284 - Very rare	27
HP:0002360	HP:0100785	Insomnia	1	CLIP2 CL E G H	7461	2586	ORPHA:904	Williams syndrome	HP:0040282 - Frequent
HP:0002360	HP:0001262	Excessive daytime somnolence	1	COA8 CL E G H	84334	20492	ORPHA:436271	Non-progressive predominantly posterior cavitating leukoencephalopathy with peripheral neuropathy	HP:0040282 - Frequent
HP:0002360	HP:0010535	Sleep apnea	1	COL13A1 CL E G H	1305	2190	ORPHA:98914	Presynaptic congenital myasthenic syndromes		6
HP:0002360	HP:0010535	Sleep apnea	1	COL3A1 CL E G H	1281	2201	ORPHA:286	Vascular Ehlers-Danlos syndrome	HP:0040283 - Occasional	749
HP:0002360	HP:0010535	Sleep apnea	1	COLQ CL E G H	8292	2226	ORPHA:98915	Synaptic congenital myasthenic syndromes	HP:0040283 - Occasional	90
HP:0002360	HP:0002494	Abnormal rapid eye movement sleep	1	COQ2 CL E G H	27235	25223	ORPHA:227510	Multiple system atrophy, cerebellar type