Human Phenotype Ontology 
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Head tremor (HP:0002346)help
Term ID: 2346
Name: Head tremor
Synonym: Head tremor
Definition: An unintentional, oscillating to-and-fro muscle movement affecting head movement.
Comments:
Reference: HP:0002346
Genes and Diseases:
 
       Child Nodes:
........expandHead titubation (HP:0002599) help

 Sister Nodes: 
..expandHand tremor (HP:0002378) help
..expandLimb tremor (HP:0200085) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0002346HP:0002346Head tremor0AARS1 CL E G H1620OMIM:619691TRICHOTHIODYSTROPHY 8, NONPHOTOSENSITIVE; TTD8
HP:0002346HP:0002346Head tremor0AFG3L2 CL E G H10939315ORPHA:101109Spinocerebellar ataxia type 28HP:0040284 - Very rare86
HP:0002346HP:0002346Head tremor0ALS2 CL E G H57679443OMIM:205100Amyotrophic lateral sclerosis 2, juvenile114
HP:0002346HP:0002346Head tremor0ALS2 CL E G H57679443ORPHA:300605Juvenile amyotrophic lateral sclerosis114
HP:0002346HP:0002346Head tremor0ANO3 CL E G H6398214004OMIM:615034Dystonia 2417
HP:0002346HP:0002346Head tremor0CACNA1G CL E G H89131394ORPHA:458803Spinocerebellar ataxia type 42HP:0040283 - Occasional32
HP:0002346HP:0002346Head tremor0CEP104 CL E G H973124866OMIM:6199885
HP:0002346HP:0002346Head tremor0CIZ1 CL E G H2579216744ORPHA:420492Adult-onset cervical dystonia, DYT23 typeHP:0040282 - Frequent16
HP:0002346HP:0002346Head tremor0DNMT1 CL E G H17862976ORPHA:314404Autosomal dominant cerebellar ataxia-deafness-narcolepsy syndromeHP:0040283 - Occasional145
HP:0002346HP:0002346Head tremor0EIF2AK2 CL E G H56109437OMIM:618877LEUKOENCEPHALOPATHY, DEVELOPMENTAL DELAY, AND EPISODIC NEUROLOGIC REGRESSION SYNDROME; LEUDEN
HP:0002346HP:0002346Head tremor0FUS CL E G H25214010ORPHA:300605Juvenile amyotrophic lateral sclerosis105
HP:0002346HP:0002346Head tremor0GBA2 CL E G H5770418986ORPHA:352641Autosomal recessive cerebellar ataxia with late-onset spasticityHP:0040283 - Occasional30
HP:0002346HP:0002346Head tremor0GBA2 CL E G H5770418986ORPHA:320391Autosomal recessive spastic paraplegia type 46HP:0040283 - Occasional30
HP:0002346HP:0002346Head tremor0GBA2 CL E G H5770418986OMIM:614409Spastic paraplegia 46, autosomal recessiveHP:0040283 - Occasional30
HP:0002346HP:0002346Head tremor0GJC2 CL E G H5716517494OMIM:608804Leukodystrophy, hypomyelinating, 237
HP:0002346HP:0002346Head tremor0HIBCH CL E G H262754908ORPHA:88639Neurodegeneration due to 3-hydroxyisobutyryl-CoA hydrolase deficiency32
HP:0002346HP:0002346Head tremor0IFRD1 CL E G H34755456ORPHA:98771Spinocerebellar ataxia type 18HP:0040283 - Occasional1
HP:0002346HP:0002346Head tremor0ITPR1 CL E G H37086180ORPHA:98769Spinocerebellar ataxia type 15/16HP:0040282 - Frequent177
HP:0002346HP:0002346Head tremor0KCNN2 CL E G H37816291OMIM:619724DYSTONIA 34, MYOCLONIC; DYT34
HP:0002346HP:0002346Head tremor0KIF1C CL E G H107496317OMIM:611302Spastic ataxia 2, autosomal recessive38
HP:0002346HP:0002346Head tremor0LAMA1 CL E G H2842176481ORPHA:370022Ataxia-intellectual disability-oculomotor apraxia-cerebellar cysts syndrome35
HP:0002346HP:0002346Head tremor0LMNB1 CL E G H40016637ORPHA:99027Adult-onset autosomal dominant leukodystrophy44
HP:0002346HP:0002346Head tremor0NEFL CL E G H47477739ORPHA:101085Charcot-Marie-Tooth disease type 1FHP:0040282 - Frequent118
HP:0002346HP:0002346Head tremor0NKX6-2 CL E G H8450419321ORPHA:527497NKX6-2-related autosomal recessive hypomyelinating leukodystrophy2
HP:0002346HP:0002346Head tremor0NKX6-2 CL E G H8450419321OMIM:617560Spastic ataxia 8, autosomal recessive, with hypomyelinating leukodystrophy2
HP:0002346HP:0002346Head tremor0NOP56 CL E G H1052815911ORPHA:276198Spinocerebellar ataxia type 36HP:0040284 - Very rare9
HP:0002346HP:0002346Head tremor0NOTCH2NLC CL E G H10099671753924OMIM:618866TREMOR, HEREDITARY ESSENTIAL, 6; ETM6
HP:0002346HP:0002346Head tremor0PEX6 CL E G H51908859ORPHA:95433Autosomal recessive spinocerebellar ataxia-blindness-deafness syndromeHP:0040282 - Frequent98
HP:0002346HP:0002346Head tremor0PI4KA CL E G H52978983OMIM:619708GASTROINTESTINAL DEFECTS AND IMMUNODEFICIENCY SYNDROME 2; GIDID211
HP:0002346HP:0002346Head tremor0PIK3R5 CL E G H2353330035ORPHA:64753Spinocerebellar ataxia with axonal neuropathy type 2HP:0040283 - Occasional11
HP:0002346HP:0002346Head tremor0PLP1 CL E G H53549086OMIM:312080Pelizaeus-Merzbacher disease60
HP:0002346HP:0002346Head tremor0PLP1 CL E G H53549086ORPHA:280219Pelizaeus-Merzbacher disease, classic formHP:0040282 - Frequent60
HP:0002346HP:0002346Head tremor0PPP2R2B CL E G H55219305OMIM:604326Spinocerebellar ataxia 12.5
HP:0002346HP:0002346Head tremor0SCP2 CL E G H634210606OMIM:613724Leukoencephalopathy with dystonia and motor neuropathy.4
HP:0002346HP:0002346Head tremor0SETX CL E G H23064445ORPHA:64753Spinocerebellar ataxia with axonal neuropathy type 2HP:0040283 - Occasional162
HP:0002346HP:0002346Head tremor0SETX CL E G H23064445OMIM:606002Spinocerebellar ataxia, autosomal recessive 1162
HP:0002346HP:0002346Head tremor0SH3TC2 CL E G H7962829427ORPHA:99949Charcot-Marie-Tooth disease type 4CHP:0040283 - Occasional493
HP:0002346HP:0002346Head tremor0SIGMAR1 CL E G H102808157ORPHA:300605Juvenile amyotrophic lateral sclerosis6
HP:0002346HP:0002346Head tremor0SPG11 CL E G H8020811226ORPHA:300605Juvenile amyotrophic lateral sclerosis287
HP:0002346HP:0002346Head tremor0SPTBN1 CL E G H671111275OMIM:619475DEVELOPMENTAL DELAY, IMPAIRED SPEECH, AND BEHAVIORAL ABNORMALITIES; DDISBA
HP:0002346HP:0002346Head tremor0SPTLC1 CL E G H1055811277ORPHA:300605Juvenile amyotrophic lateral sclerosis54
HP:0002346HP:0002346Head tremor0STUB1 CL E G H1027311427ORPHA:412057Autosomal recessive cerebellar ataxia due to STUB1 deficiencyHP:0040283 - Occasional14
HP:0002346HP:0002346Head tremor0TMEM63A CL E G H972529118OMIM:618688LEUKODYSTROPHY, HYPOMYELINATING, 19, TRANSIENT INFANTILE; HLD19
HP:0002346HP:0002346Head tremor0TRIM8 CL E G H8160315579OMIM:619428FOCAL SEGMENTAL GLOMERULOSCLEROSIS AND NEURODEVELOPMENTAL SYNDROME; FSGSNEDS1
HP:0002346HP:0002346Head tremor0UCHL1 CL E G H734512513OMIM:615491Spastic paraplegia 79, autosomal recessive21
HP:0002346HP:0002346Head tremor0VPS13A CL E G H232301908ORPHA:2388Choreoacanthocytosis130
HP:0002346HP:0002599Head titubation1AARS1 CL E G H1620OMIM:619691TRICHOTHIODYSTROPHY 8, NONPHOTOSENSITIVE; TTD8
HP:0002346HP:0002599Head titubation1ALS2 CL E G H57679443OMIM:205100Amyotrophic lateral sclerosis 2, juvenile114
HP:0002346HP:0002599Head titubation1ALS2 CL E G H57679443ORPHA:300605Juvenile amyotrophic lateral sclerosisHP:0040283 - Occasional114
HP:0002346HP:0002599Head titubation1EIF2AK2 CL E G H56109437OMIM:618877LEUKOENCEPHALOPATHY, DEVELOPMENTAL DELAY, AND EPISODIC NEUROLOGIC REGRESSION SYNDROME; LEUDEN
HP:0002346HP:0002599Head titubation1FUS CL E G H25214010ORPHA:300605Juvenile amyotrophic lateral sclerosisHP:0040283 - Occasional105
HP:0002346HP:0002599Head titubation1GJC2 CL E G H5716517494OMIM:608804Leukodystrophy, hypomyelinating, 2.37
HP:0002346HP:0002599Head titubation1HIBCH CL E G H262754908ORPHA:88639Neurodegeneration due to 3-hydroxyisobutyryl-CoA hydrolase deficiencyHP:0040284 - Very rare32
HP:0002346HP:0002599Head titubation1KIF1C CL E G H107496317OMIM:611302Spastic ataxia 2, autosomal recessive.38
HP:0002346HP:0002599Head titubation1LAMA1 CL E G H2842176481ORPHA:370022Ataxia-intellectual disability-oculomotor apraxia-cerebellar cysts syndromeHP:0040283 - Occasional35
HP:0002346HP:0002599Head titubation1LMNB1 CL E G H40016637ORPHA:99027Adult-onset autosomal dominant leukodystrophyHP:0040283 - Occasional44
HP:0002346HP:0002599Head titubation1NKX6-2 CL E G H8450419321ORPHA:527497NKX6-2-related autosomal recessive hypomyelinating leukodystrophyHP:0040282 - Frequent2
HP:0002346HP:0002599Head titubation1NKX6-2 CL E G H8450419321OMIM:617560Spastic ataxia 8, autosomal recessive, with hypomyelinating leukodystrophy.2
HP:0002346HP:0002599Head titubation1PI4KA CL E G H52978983OMIM:619708GASTROINTESTINAL DEFECTS AND IMMUNODEFICIENCY SYNDROME 2; GIDID211
HP:0002346HP:0002599Head titubation1PLP1 CL E G H53549086OMIM:312080Pelizaeus-Merzbacher disease60
HP:0002346HP:0002599Head titubation1SIGMAR1 CL E G H102808157ORPHA:300605Juvenile amyotrophic lateral sclerosisHP:0040283 - Occasional6
HP:0002346HP:0002599Head titubation1SPG11 CL E G H8020811226ORPHA:300605Juvenile amyotrophic lateral sclerosisHP:0040283 - Occasional287
HP:0002346HP:0002599Head titubation1SPTBN1 CL E G H671111275OMIM:619475DEVELOPMENTAL DELAY, IMPAIRED SPEECH, AND BEHAVIORAL ABNORMALITIES; DDISBA
HP:0002346HP:0002599Head titubation1SPTLC1 CL E G H1055811277ORPHA:300605Juvenile amyotrophic lateral sclerosisHP:0040283 - Occasional54
HP:0002346HP:0002599Head titubation1TMEM63A CL E G H972529118OMIM:618688LEUKODYSTROPHY, HYPOMYELINATING, 19, TRANSIENT INFANTILE; HLD19
HP:0002346HP:0002599Head titubation1UCHL1 CL E G H734512513OMIM:615491Spastic paraplegia 79, autosomal recessive.21
HP:0002346HP:0002599Head titubation1VPS13A CL E G H232301908ORPHA:2388ChoreoacanthocytosisHP:0040283 - Occasional130


Genes (40) :AARS1 AFG3L2 ALS2 ANO3 CACNA1G CEP104 CIZ1 DNMT1 EIF2AK2 FUS GBA2 GJC2 HIBCH IFRD1 ITPR1 KCNN2 KIF1C LAMA1 LMNB1 NEFL NKX6-2 NOP56 NOTCH2NLC PEX6 PI4KA PIK3R5 PLP1 PPP2R2B SCP2 SETX SH3TC2 SIGMAR1 SPG11 SPTBN1 SPTLC1 STUB1 TMEM63A TRIM8 UCHL1 VPS13A

Diseases (41) :OMIM:619691 ORPHA:101109 OMIM:205100 ORPHA:300605 OMIM:615034 ORPHA:458803 OMIM:619988 ORPHA:420492 ORPHA:314404 OMIM:618877 ORPHA:352641 ORPHA:320391 OMIM:614409 OMIM:608804 ORPHA:88639 ORPHA:98771 ORPHA:98769 OMIM:619724 OMIM:611302 ORPHA:370022 ORPHA:99027 ORPHA:101085 ORPHA:527497 OMIM:617560 ORPHA:276198 OMIM:618866 ORPHA:95433 OMIM:619708 ORPHA:64753 OMIM:312080 ORPHA:280219 OMIM:604326 OMIM:613724 OMIM:606002 ORPHA:99949 OMIM:619475 ORPHA:412057 OMIM:618688 OMIM:619428 OMIM:615491 ORPHA:2388
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.