Human Phenotype Ontology 
Grandparent Node:
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Tremor (HP:0001337)help
Parent Node:
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Action tremor (HP:0002345)help
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Postural tremor (HP:0002174)help
Term ID: 2174
Name: Postural tremor
Synonym: Tremor, postural
Definition: A type of tremors that is triggered by holding a limb in a fixed position.
Comments:
Reference: HP:0002174
Genes and Diseases:
 
       Child Nodes:
........expandUpper limb postural tremor (HP:0007351) help

 Sister Nodes: 
..expandIsometric tremor (HP:0030185) help
..expandKinetic tremor (HP:0030186) help
..expandTitubation (HP:0030187) help
..expandVocal tremor (HP:0012477) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0002174HP:0002174Postural tremor0ALDH18A1 CL E G H58329722ORPHA:447757Autosomal dominant spastic paraplegia type 9BHP:0040282 - Frequent89
HP:0002174HP:0002174Postural tremor0ALDH18A1 CL E G H58329722ORPHA:447760Autosomal recessive spastic paraplegia type 9BHP:0040282 - Frequent89
HP:0002174HP:0002174Postural tremor0ANO3 CL E G H6398214004ORPHA:420485Cranio-cervical dystonia with laryngeal and upper-limb involvement17
HP:0002174HP:0002174Postural tremor0ATP13A2 CL E G H2340030213ORPHA:314632ATP13A2-related juvenile neuronal ceroid lipofuscinosisHP:0040284 - Very rare100
HP:0002174HP:0002174Postural tremor0ATP6 CL E G H45087414ORPHA:104Leber hereditary optic neuropathyHP:0040283 - Occasional
HP:0002174HP:0002174Postural tremor0ATP6 CL E G H45087414OMIM:535000Leber optic atrophy.
HP:0002174HP:0002174Postural tremor0ATXN1 CL E G H631010548ORPHA:98755Spinocerebellar ataxia type 1HP:0040283 - Occasional19
HP:0002174HP:0002174Postural tremor0ATXN2 CL E G H631110555OMIM:183090Spinocerebellar ataxia 2.11
HP:0002174HP:0002174Postural tremor0ATXN2 CL E G H631110555ORPHA:98756Spinocerebellar ataxia type 2HP:0040282 - Frequent11
HP:0002174HP:0002174Postural tremor0BSCL2 CL E G H2658015832ORPHA:100998Autosomal dominant spastic paraplegia type 17HP:0040283 - Occasional105
HP:0002174HP:0002174Postural tremor0BSCL2 CL E G H2658015832OMIM:270685Spastic paraplegia 17105
HP:0002174HP:0002174Postural tremor0CACNA1G CL E G H89131394ORPHA:458803Spinocerebellar ataxia type 4232
HP:0002174HP:0002174Postural tremor0CARS2 CL E G H7958725695ORPHA:477774Combined oxidative phosphorylation defect type 2735
HP:0002174HP:0002174Postural tremor0COL6A3 CL E G H12932213OMIM:616411Dystonia 27.702
HP:0002174HP:0002174Postural tremor0COL6A3 CL E G H12932213ORPHA:464440Primary dystonia, DYT27 type702
HP:0002174HP:0002174Postural tremor0COQ2 CL E G H2723525223ORPHA:227510Multiple system atrophy, cerebellar typeHP:0040282 - Frequent54
HP:0002174HP:0002174Postural tremor0COQ2 CL E G H2723525223ORPHA:98933Multiple system atrophy, parkinsonian typeHP:0040283 - Occasional54
HP:0002174HP:0002174Postural tremor0COX1 CL E G H45127419ORPHA:104Leber hereditary optic neuropathyHP:0040283 - Occasional
HP:0002174HP:0002174Postural tremor0COX3 CL E G H45147422ORPHA:104Leber hereditary optic neuropathyHP:0040283 - Occasional
HP:0002174HP:0002174Postural tremor0COX3 CL E G H45147422OMIM:535000Leber optic atrophy.
HP:0002174HP:0002174Postural tremor0CYP7B1 CL E G H94202652OMIM:270800Spastic paraplegia 5A, autosomal recessive57
HP:0002174HP:0002174Postural tremor0CYTB CL E G H45197427ORPHA:104Leber hereditary optic neuropathyHP:0040283 - Occasional
HP:0002174HP:0002174Postural tremor0CYTB CL E G H45197427OMIM:535000Leber optic atrophy.
HP:0002174HP:0002174Postural tremor0DNAJC30 CL E G H8427716410ORPHA:104Leber hereditary optic neuropathyHP:0040283 - Occasional
HP:0002174HP:0002174Postural tremor0DRD3 CL E G H18143024OMIM:190300Tremor, hereditary essential, 1.21
HP:0002174HP:0002174Postural tremor0FGF14 CL E G H22593671OMIM:193003Nystagmus 4, congenital, autosomal dominant47
HP:0002174HP:0002174Postural tremor0FMR1 CL E G H23323775OMIM:300623Fragile X tremor/ataxia syndrome.30
HP:0002174HP:0002174Postural tremor0FUS CL E G H25214010OMIM:614782TREMOR, HEREDITARY ESSENTIAL, 4; ETM4105
HP:0002174HP:0002174Postural tremor0GALT CL E G H25924135ORPHA:79239Classic galactosemiaHP:0040282 - Frequent351
HP:0002174HP:0002174Postural tremor0GCH1 CL E G H26434193ORPHA:98808Autosomal dominant dopa-responsive dystoniaHP:0040282 - Frequent86
HP:0002174HP:0002174Postural tremor0GCH1 CL E G H26434193OMIM:128230Dystonia, DOPA-responsive, with or without hyperphenylalaninemia.86
HP:0002174HP:0002174Postural tremor0IMPDH2 CL E G H36156053ORPHA:98808Autosomal dominant dopa-responsive dystoniaHP:0040282 - Frequent1
HP:0002174HP:0002174Postural tremor0ITPR1 CL E G H37086180OMIM:206700Gillespie syndrome.177
HP:0002174HP:0002174Postural tremor0ITPR1 CL E G H37086180OMIM:606658Spinocerebellar ataxia 15.177
HP:0002174HP:0002174Postural tremor0ITPR1 CL E G H37086180ORPHA:98769Spinocerebellar ataxia type 15/16177
HP:0002174HP:0002174Postural tremor0KCND3 CL E G H37526239OMIM:607346Spinocerebellar ataxia 19.35
HP:0002174HP:0002174Postural tremor0LMNB1 CL E G H40016637ORPHA:99027Adult-onset autosomal dominant leukodystrophy44
HP:0002174HP:0002174Postural tremor0MFN2 CL E G H992716877ORPHA:99947Autosomal dominant Charcot-Marie-Tooth disease type 2A2HP:0040283 - Occasional203
HP:0002174HP:0002174Postural tremor0MPZ CL E G H43597225ORPHA:3115Roussy-Lévy syndromeHP:0040282 - Frequent134
HP:0002174HP:0002174Postural tremor0MPZ CL E G H43597225OMIM:180800Roussy-Levy hereditary areflexic dystasia134
HP:0002174HP:0002174Postural tremor0MYBPC1 CL E G H46047549OMIM:618524MYOPATHY, CONGENITAL, WITH TREMOR; MYOTREM66
HP:0002174HP:0002174Postural tremor0ND1 CL E G H45357455ORPHA:104Leber hereditary optic neuropathyHP:0040283 - Occasional
HP:0002174HP:0002174Postural tremor0ND1 CL E G H45357455OMIM:535000Leber optic atrophy.
HP:0002174HP:0002174Postural tremor0ND2 CL E G H45367456ORPHA:104Leber hereditary optic neuropathyHP:0040283 - Occasional
HP:0002174HP:0002174Postural tremor0ND2 CL E G H45367456OMIM:535000Leber optic atrophy.
HP:0002174HP:0002174Postural tremor0ND4 CL E G H45387459ORPHA:104Leber hereditary optic neuropathyHP:0040283 - Occasional
HP:0002174HP:0002174Postural tremor0ND4 CL E G H45387459OMIM:535000Leber optic atrophy.
HP:0002174HP:0002174Postural tremor0ND4L CL E G H45397460ORPHA:104Leber hereditary optic neuropathyHP:0040283 - Occasional
HP:0002174HP:0002174Postural tremor0ND4L CL E G H45397460OMIM:535000Leber optic atrophy.
HP:0002174HP:0002174Postural tremor0ND5 CL E G H45407461ORPHA:104Leber hereditary optic neuropathyHP:0040283 - Occasional
HP:0002174HP:0002174Postural tremor0ND5 CL E G H45407461OMIM:535000Leber optic atrophy.
HP:0002174HP:0002174Postural tremor0ND6 CL E G H45417462ORPHA:104Leber hereditary optic neuropathyHP:0040283 - Occasional
HP:0002174HP:0002174Postural tremor0ND6 CL E G H45417462OMIM:535000Leber optic atrophy.
HP:0002174HP:0002174Postural tremor0NDRG1 CL E G H103977679ORPHA:99950Charcot-Marie-Tooth disease type 4DHP:0040283 - Occasional82
HP:0002174HP:0002174Postural tremor0NDUFS2 CL E G H47207708ORPHA:104Leber hereditary optic neuropathyHP:0040283 - Occasional65
HP:0002174HP:0002174Postural tremor0NIPA1 CL E G H12360617043ORPHA:100988Autosomal dominant spastic paraplegia type 6HP:0040283 - Occasional117
HP:0002174HP:0002174Postural tremor0NOTCH2NLC CL E G H10099671753924OMIM:618866TREMOR, HEREDITARY ESSENTIAL, 6; ETM6
HP:0002174HP:0002174Postural tremor0NR4A2 CL E G H49297981OMIM:61991127
HP:0002174HP:0002174Postural tremor0NR4A2 CL E G H49297981ORPHA:98808Autosomal dominant dopa-responsive dystoniaHP:0040282 - Frequent27
HP:0002174HP:0002174Postural tremor0OPA3 CL E G H802078142ORPHA:67036Autosomal dominant optic atrophy and cataractHP:0040282 - Frequent163
HP:0002174HP:0002174Postural tremor0PARK7 CL E G H1131516369OMIM:606324PARKINSON DISEASE 7, AUTOSOMAL RECESSIVE EARLY-ONSET; PARK723
HP:0002174HP:0002174Postural tremor0PIGA CL E G H52778957OMIM:301072NEURODEVELOPMENTAL DISORDER WITH EPILEPSY AND HEMOCHROMATOSIS; NEDEPH46
HP:0002174HP:0002174Postural tremor0PIK3R5 CL E G H2353330035ORPHA:64753Spinocerebellar ataxia with axonal neuropathy type 2HP:0040283 - Occasional11
HP:0002174HP:0002174Postural tremor0PLA2G6 CL E G H83989039OMIM:612953Parkinson disease 14, autosomal recessive133
HP:0002174HP:0002174Postural tremor0PMP22 CL E G H53769118ORPHA:3115Roussy-Lévy syndromeHP:0040282 - Frequent79
HP:0002174HP:0002174Postural tremor0PMP22 CL E G H53769118OMIM:180800Roussy-Levy hereditary areflexic dystasia79
HP:0002174HP:0002174Postural tremor0POLR3A CL E G H1112830074OMIM:607694Leukodystrophy, hypomyelinating, 7, with or without oligodontia and/orhypogonadotropic hypogonadism.138
HP:0002174HP:0002174Postural tremor0POLR3A CL E G H1112830074ORPHA:447896Tremor-ataxia-central hypomyelination syndromeHP:0040282 - Frequent138
HP:0002174HP:0002174Postural tremor0POLR3B CL E G H5570330348OMIM:607694Leukodystrophy, hypomyelinating, 7, with or without oligodontia and/orhypogonadotropic hypogonadism.67
HP:0002174HP:0002174Postural tremor0PPP2R2B CL E G H55219305ORPHA:98762Spinocerebellar ataxia type 12HP:0040283 - Occasional5
HP:0002174HP:0002174Postural tremor0PRDX3 CL E G H109359354OMIM:619862
HP:0002174HP:0002174Postural tremor0PRKRA CL E G H85759438OMIM:612067Dystonia 16.37
HP:0002174HP:0002174Postural tremor0PRKRA CL E G H85759438ORPHA:210571Dystonia 16HP:0040282 - Frequent37
HP:0002174HP:0002174Postural tremor0REEP2 CL E G H5130817975ORPHA:401849Autosomal spastic paraplegia type 72HP:0040283 - Occasional3
HP:0002174HP:0002174Postural tremor0RILPL1 CL E G H35311626814OMIM:619790OCULOPHARYNGODISTAL MYOPATHY 4; OPDM4
HP:0002174HP:0002174Postural tremor0SCARB2 CL E G H9501665OMIM:254900Epilepsy, progressive myoclonic, 4, with or without renal failure.77
HP:0002174HP:0002174Postural tremor0SETX CL E G H23064445ORPHA:64753Spinocerebellar ataxia with axonal neuropathy type 2HP:0040283 - Occasional162
HP:0002174HP:0002174Postural tremor0STUB1 CL E G H1027311427ORPHA:412057Autosomal recessive cerebellar ataxia due to STUB1 deficiencyHP:0040283 - Occasional14
HP:0002174HP:0002174Postural tremor0TENM4 CL E G H2601129945OMIM:616736Tremor, hereditary essential, 55
HP:0002174HP:0002174Postural tremor0TH CL E G H705411782ORPHA:101150Autosomal recessive dopa-responsive dystoniaHP:0040282 - Frequent80
HP:0002174HP:0002174Postural tremor0TMEM240 CL E G H33945325186OMIM:607454Spinocerebellar ataxia 219
HP:0002174HP:0002174Postural tremor0TPP1 CL E G H12002073ORPHA:284324Childhood-onset autosomal recessive slowly progressive spinocerebellar ataxiaHP:0040283 - Occasional203
HP:0002174HP:0002174Postural tremor0TPP1 CL E G H12002073OMIM:609270Spinocerebellar ataxia, autosomal recessive 7.203
HP:0002174HP:0002174Postural tremor0TSPOAP1 CL E G H925616831ORPHA:101150Autosomal recessive dopa-responsive dystoniaHP:0040282 - Frequent2
HP:0002174HP:0002174Postural tremor0TUBB4A CL E G H1038220774ORPHA:98805Primary dystonia, DYT4 type66
HP:0002174HP:0002174Postural tremor0UCHL1 CL E G H734512513OMIM:615491Spastic paraplegia 79, autosomal recessive21
HP:0002174HP:0002174Postural tremor0VAPB CL E G H921712649OMIM:608627Amyotrophic lateral sclerosis 8116
HP:0002174HP:0007351Upper limb postural tremor1ANO3 CL E G H6398214004ORPHA:420485Cranio-cervical dystonia with laryngeal and upper-limb involvementHP:0040283 - Occasional17
HP:0002174HP:0007351Upper limb postural tremor1CACNA1G CL E G H89131394ORPHA:458803Spinocerebellar ataxia type 42HP:0040283 - Occasional32
HP:0002174HP:0007351Upper limb postural tremor1CARS2 CL E G H7958725695ORPHA:477774Combined oxidative phosphorylation defect type 27HP:0040283 - Occasional35
HP:0002174HP:0007351Upper limb postural tremor1COL6A3 CL E G H12932213ORPHA:464440Primary dystonia, DYT27 typeHP:0040282 - Frequent702
HP:0002174HP:0007351Upper limb postural tremor1ITPR1 CL E G H37086180ORPHA:98769Spinocerebellar ataxia type 15/16HP:0040282 - Frequent177
HP:0002174HP:0007351Upper limb postural tremor1LMNB1 CL E G H40016637ORPHA:99027Adult-onset autosomal dominant leukodystrophyHP:0040283 - Occasional44
HP:0002174HP:0007351Upper limb postural tremor1MPZ CL E G H43597225OMIM:180800Roussy-Levy hereditary areflexic dystasia.134
HP:0002174HP:0007351Upper limb postural tremor1PLA2G6 CL E G H83989039OMIM:612953Parkinson disease 14, autosomal recessive133
HP:0002174HP:0007351Upper limb postural tremor1PMP22 CL E G H53769118OMIM:180800Roussy-Levy hereditary areflexic dystasia.79
HP:0002174HP:0007351Upper limb postural tremor1TUBB4A CL E G H1038220774ORPHA:98805Primary dystonia, DYT4 typeHP:0040283 - Occasional66


Genes (64) :ALDH18A1 ANO3 ATP13A2 ATP6 ATXN1 ATXN2 BSCL2 CACNA1G CARS2 COL6A3 COQ2 COX1 COX3 CYP7B1 CYTB DNAJC30 DRD3 FGF14 FMR1 FUS GALT GCH1 IMPDH2 ITPR1 KCND3 LMNB1 MFN2 MPZ MYBPC1 ND1 ND2 ND4 ND4L ND5 ND6 NDRG1 NDUFS2 NIPA1 NOTCH2NLC NR4A2 OPA3 PARK7 PIGA PIK3R5 PLA2G6 PMP22 POLR3A POLR3B PPP2R2B PRDX3 PRKRA REEP2 RILPL1 SCARB2 SETX STUB1 TENM4 TH TMEM240 TPP1 TSPOAP1 TUBB4A UCHL1 VAPB

Diseases (61) :ORPHA:447757 ORPHA:447760 ORPHA:420485 ORPHA:314632 ORPHA:104 OMIM:535000 ORPHA:98755 OMIM:183090 ORPHA:98756 ORPHA:100998 OMIM:270685 ORPHA:458803 ORPHA:477774 OMIM:616411 ORPHA:464440 ORPHA:227510 ORPHA:98933 OMIM:270800 OMIM:190300 OMIM:193003 OMIM:300623 OMIM:614782 ORPHA:79239 ORPHA:98808 OMIM:128230 OMIM:206700 OMIM:606658 ORPHA:98769 OMIM:607346 ORPHA:99027 ORPHA:99947 ORPHA:3115 OMIM:180800 OMIM:618524 ORPHA:99950 ORPHA:100988 OMIM:618866 OMIM:619911 ORPHA:67036 OMIM:606324 OMIM:301072 ORPHA:64753 OMIM:612953 OMIM:607694 ORPHA:447896 ORPHA:98762 OMIM:619862 OMIM:612067 ORPHA:210571 ORPHA:401849 OMIM:619790 OMIM:254900 ORPHA:412057 OMIM:616736 ORPHA:101150 OMIM:607454 ORPHA:284324 OMIM:609270 ORPHA:98805 OMIM:615491 OMIM:608627
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.