Human Phenotype
Ontology
Grandparent Node: Headache (HP:0002315) Parent Node: Migraine (HP:0002076) ..Starting node Migraine with aura (HP:0002077)
Term ID: 2077
Name: Migraine with aura
Synonym:
Definition: A type of migraine in which there is an aura characterized by focal neurological phenomena that usually proceed, but may accompany or occur in the absence of, the headache. The symptoms of an aura may include fully reversible visual, sensory, and speech symptoms but not motor weakness. Visual symptoms may include flickering lights, spots and lines and/or loss of vision and/or unilateral sensory symptoms such as paresthesias or numbness. At least one of the symptoms of an aura develops gradually over 5 or more minutes and/or different symptoms occur in succession.
Comments:
Reference: HP:0002077
Genes and Diseases: Child Nodes: Sister Nodes: ..Migraine without aura (HP:0002083) Input HPO ID HPO term Distance Gene Gene id entrez HGNC ID DiseaseId DiseaseName Frequency Onset HGMD variants ClinVar variants HP:0002077 HP:0002077 Migraine with aura 0 ATP1A2 CL E G H 477 800 ORPHA:569 Familial or sporadic hemiplegic migraine HP:0040281 - Very frequent 239 HP:0002077 HP:0002077 Migraine with aura 0 ATP1A2 CL E G H 477 800 OMIM:602481 Migraine, familial hemiplegic, 2 . 239 HP:0002077 HP:0002077 Migraine with aura 0 CACNA1A CL E G H 773 1388 ORPHA:569 Familial or sporadic hemiplegic migraine HP:0040281 - Very frequent 449 HP:0002077 HP:0002077 Migraine with aura 0 CACNA1A CL E G H 773 1388 OMIM:141500 Migraine, familial hemiplegic, 1 . 449 HP:0002077 HP:0002077 Migraine with aura 0 COL4A1 CL E G H 1282 2202 OMIM:175780 Brain small vessel disease 1 with or without ocular anomalies 193 HP:0002077 HP:0002077 Migraine with aura 0 CSNK1D CL E G H 1453 2452 OMIM:615224 Advanced sleep phase syndrome, familial, 2 2 HP:0002077 HP:0002077 Migraine with aura 0 EDNRA CL E G H 1909 3179 OMIM:157300 Migraine with or without aura, susceptibility to, 1 . 3 HP:0002077 HP:0002077 Migraine with aura 0 ESR1 CL E G H 2099 3467 OMIM:157300 Migraine with or without aura, susceptibility to, 1 . 13 HP:0002077 HP:0002077 Migraine with aura 0 KCNK18 CL E G H 338567 19439 OMIM:613656 MIGRAINE WITH OR WITHOUT AURA, SUSCEPTIBILITY TO, 13; MGR13 4 HP:0002077 HP:0002077 Migraine with aura 0 NOTCH3 CL E G H 4854 7883 ORPHA:136 Cerebral autosomal dominant arteriopathy-subcortical infarcts-leukoencephalopathy HP:0040282 - Frequent 144 HP:0002077 HP:0002077 Migraine with aura 0 PRRT2 CL E G H 112476 30500 ORPHA:569 Familial or sporadic hemiplegic migraine HP:0040281 - Very frequent 94 HP:0002077 HP:0002077 Migraine with aura 0 SCN1A CL E G H 6323 10585 ORPHA:569 Familial or sporadic hemiplegic migraine HP:0040281 - Very frequent 1053 HP:0002077 HP:0002077 Migraine with aura 0 SCN1A CL E G H 6323 10585 OMIM:609634 Migraine, familial hemiplegic, 3 . 1053 HP:0002077 HP:0002077 Migraine with aura 0 TNF CL E G H 7124 11892 OMIM:157300 Migraine with or without aura, susceptibility to, 1 . 7 HP:0002077 HP:0002077 Migraine with aura 0 TREX1 CL E G H 11277 12269 ORPHA:247691 Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations HP:0040283 - Occasional 56
Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.
