Human Phenotype Ontology 
Grandparent Node:
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Abnormality of the gastrointestinal tract (HP:0011024)help
Grandparent Node:
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Neoplasm by anatomical site (HP:0011793)help
Parent Node:
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Neoplasm of the gastrointestinal tract (HP:0007378)help
..Starting node
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Zollinger-Ellison syndrome (HP:0002044)help
Term ID: 2044
Name: Zollinger-Ellison syndrome
Synonym:
Definition: A condition in which there is increased production of gastrin by a gastrin-secreting tumor (usually located in the pancreas, duodenum, or abdominal lymph nodes) that stimulates the gastric mucosa to maximal activity, with consequent gastrointestinal mucosal ulceration.
Comments:
Reference: HP:0002044
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAmpulla of Vater carcinoma (HP:0031524) help
..expandBenign gastrointestinal tract tumors (HP:0006719) help
..expandBiliary tract neoplasm (HP:0100574) help
..expandDesmoid tumors (HP:0100245) help
..expandEsophageal neoplasm (HP:0100751) help
..expandGastrointestinal stroma tumor (HP:0100723) help
..expandIntestinal carcinoid (HP:0006723) help
..expandIntestinal polyp (HP:0005266) help
..expandMalignant gastrointestinal tract tumors (HP:0006749) help
..expandMultiple intestinal neurofibromatosis (HP:0005220) help
..expandNeoplasm of the large intestine (HP:0100834) help
..expandNeoplasm of the liver (HP:0002896) help
..expandNeoplasm of the small intestine (HP:0100833) help
..expandNeoplasm of the stomach (HP:0006753) help
..expandPrimary peritoneal carcinoma (HP:0030406) help
InputHPO IDHPO termDistanceGeneGene id entrezDiseaseIdDiseaseNameDiseaseMIMConceptIDSourceTypical associationHGMD variantsClinVar variantsHGNC IDGeneMIM
 
HPO disease - gene - phenotype typical associations:
HP:0002044HP:0002044Zollinger-Ellison syndrome0CDKN1A CL E G H1026652AmebiasisORPHA181784116899
HP:0002044HP:0002044Zollinger-Ellison syndrome0CDKN1B CL E G H1027276152ORPHA1251785600778
HP:0002044HP:0002044Zollinger-Ellison syndrome0CDKN1B CL E G H1027652AmebiasisORPHA1251785600778
HP:0002044HP:0002044Zollinger-Ellison syndrome0CDKN2B CL E G H1030652AmebiasisORPHA1141788600431
HP:0002044HP:0002044Zollinger-Ellison syndrome0CDKN2C CL E G H1031652AmebiasisORPHA121789603369
HP:0002044HP:0002044Zollinger-Ellison syndrome0MEN1 CL E G H422197279ORPHA17487010613733
HP:0002044HP:0002044Zollinger-Ellison syndrome0MEN1 CL E G H4221652AmebiasisORPHA17487010613733
HP:0002044HP:0002044Zollinger-Ellison syndrome0MEN1 CL E G H4221131100Multiple endocrine neoplasia, type 1131100C0025267OMIM17487010613733
HP:0002044HP:0002044Zollinger-Ellison syndrome0PIEZO2 CL E G H63895248700Marden-Walker syndrome248700C0796033OMIM13226270613629
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0002044HP:0002044Zollinger-Ellison syndrome0ATRX CL E G H546100075ORPHA0170886300032
HP:0002044HP:0002044Zollinger-Ellison syndrome0DAXX CL E G H1616100075ORPHA02681603186


Genes (8) :ATRX CDKN1A CDKN1B CDKN2B CDKN2C DAXX MEN1 PIEZO2

Diseases (6) :100075 652 276152 97279 131100 248700
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is June 2019 release.