Human Phenotype Ontology 
Grandparent Node:
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Abnormality of the nail (HP:0001597)help
Parent Node:
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Nail dysplasia (HP:0002164)help
..Starting node
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Ridged nail (HP:0001807)help
Term ID: 1807
Name: Ridged nail
Synonym: Grooved nails; Longitudinal ridging; Nail ridging; Ridged nails
Definition: Longitudinal, linear prominences in the nail plate.
Comments:
Reference: HP:0001807
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandBifid nail (HP:0010793) help
..expandBroad nail (HP:0001821) help
..expandConcave nail (HP:0001598) help
..expandCongenital onychodystrophy (HP:0008394) help
..expandDeep-set nails (HP:0001814) help
..expandFingernail dysplasia (HP:0100798) help
..expandFused nails (HP:0011312) help
..expandHyperconvex nail (HP:0001795) help
..expandNail pits (HP:0001803) help
..expandNarrow nail (HP:0011313) help
..expandPlatonychia (HP:0030803) help
..expandSplit nail (HP:0001809) help
..expandToenail dysplasia (HP:0100797) help
..expandTrachyonychia (HP:0030804) help
InputHPO IDHPO termDistanceGeneGene id entrezDiseaseIdDiseaseNameDiseaseMIMConceptIDSourceTypical associationHGMD variantsClinVar variantsHGNC IDGeneMIM
 
HPO disease - gene - phenotype typical associations:
HP:0001807HP:0001807Ridged nail0ATP2A2 CL E G H488101900Acrokeratosis verruciformis of Hopf101900C0265971OMIM1184812108740
HP:0001807HP:0001807Ridged nail0ATP2A2 CL E G H488101900Acrokeratosis verruciformis of Hopf101900C0265971OMIM1180812108740
HP:0001807HP:0001807Ridged nail0ATP2A2 CL E G H488124200Keratosis follicularis124200C0022595OMIM1184812108740
HP:0001807HP:0001807Ridged nail0ATP2A2 CL E G H488124200Keratosis follicularis124200C0022595OMIM1180812108740
HP:0001807HP:0001807Ridged nail0CTSK CL E G H1513763ORPHA11862536601105
HP:0001807HP:0001807Ridged nail0CTSK CL E G H1513763ORPHA11632536601105
HP:0001807HP:0001807Ridged nail0CTSK CL E G H1513265800Pyknodysostosis265800C0238402OMIM11862536601105
HP:0001807HP:0001807Ridged nail0CTSK CL E G H1513265800Pyknodysostosis265800C0238402OMIM11632536601105
HP:0001807HP:0001807Ridged nail0DKC1 CL E G H1736305000Dyskeratosis congenita X-linked305000C1148551OMIM14262890300126
HP:0001807HP:0001807Ridged nail0DKC1 CL E G H1736305000Dyskeratosis congenita X-linked305000C1148551OMIM13962890300126
HP:0001807HP:0001807Ridged nail0EFNB1 CL E G H1947304110Craniofrontonasal dysplasia304110C0220767OMIM12103226300035
HP:0001807HP:0001807Ridged nail0EFNB1 CL E G H1947304110Craniofrontonasal dysplasia304110C0220767OMIM12013226300035
HP:0001807HP:0001807Ridged nail0FERMT1 CL E G H55612173650Kindler's syndrome173650C0406557OMIM137215889607900
HP:0001807HP:0001807Ridged nail0FERMT1 CL E G H55612173650Kindler's syndrome173650C0406557OMIM130115889607900
HP:0001807HP:0001807Ridged nail0FOXN1 CL E G H8456169095ORPHA136812765600838
HP:0001807HP:0001807Ridged nail0FOXN1 CL E G H8456169095ORPHA130512765600838
HP:0001807HP:0001807Ridged nail0FOXN1 CL E G H8456601705T-cell immunodeficiency, congenital alopecia and nail dystrophy601705C1866426OMIM136812765600838
HP:0001807HP:0001807Ridged nail0FOXN1 CL E G H8456601705T-cell immunodeficiency, congenital alopecia and nail dystrophy601705C1866426OMIM130512765600838
HP:0001807HP:0001807Ridged nail0IKBKG CL E G H8517308300Incontinentia pigmenti syndrome308300C0021171OMIM13375961300248
HP:0001807HP:0001807Ridged nail0IKBKG CL E G H8517308300Incontinentia pigmenti syndrome308300C0021171OMIM13265961300248
HP:0001807HP:0001807Ridged nail0KRT14 CL E G H3861601001Epidermolysis bullosa simplex, autosomal recessive601001C1832926OMIM11556416148066
HP:0001807HP:0001807Ridged nail0KRT14 CL E G H3861601001Epidermolysis bullosa simplex, autosomal recessive601001C1832926OMIM11486416148066
HP:0001807HP:0001807Ridged nail0KRT5 CL E G H3852601001Epidermolysis bullosa simplex, autosomal recessive601001C1832926OMIM12526442148040
HP:0001807HP:0001807Ridged nail0KRT5 CL E G H3852601001Epidermolysis bullosa simplex, autosomal recessive601001C1832926OMIM12416442148040
HP:0001807HP:0001807Ridged nail0LMX1B CL E G H40102614ORPHA14306654602575
HP:0001807HP:0001807Ridged nail0LMX1B CL E G H40102614ORPHA13746654602575
HP:0001807HP:0001807Ridged nail0LMX1B CL E G H4010161200Nail-patella syndrome161200C0027341OMIM14306654602575
HP:0001807HP:0001807Ridged nail0LMX1B CL E G H4010161200Nail-patella syndrome161200C0027341OMIM13746654602575
HP:0001807HP:0001807Ridged nail0MSX1 CL E G H4487189500Hypoplastic enamel-onycholysis-hypohidrosis syndrome189500C0406735OMIM11587391142983
HP:0001807HP:0001807Ridged nail0MSX1 CL E G H4487189500Hypoplastic enamel-onycholysis-hypohidrosis syndrome189500C0406735OMIM11507391142983
HP:0001807HP:0001807Ridged nail0SLC39A4 CL E G H5563037Chromosome 3, monosomy 3pC0795806ORPHA148617129607059
HP:0001807HP:0001807Ridged nail0SLC39A4 CL E G H5563037Chromosome 3, monosomy 3pC0795806ORPHA144917129607059
HP:0001807HP:0001807Ridged nail0TERC CL E G H7012127550Dyskeratosis congenita autosomal dominant127550C1851970OMIM129111727602322
HP:0001807HP:0001807Ridged nail0TERC CL E G H7012127550Dyskeratosis congenita autosomal dominant127550C1851970OMIM122711727602322
HP:0001807HP:0001807Ridged nail0TERT CL E G H7015127550Dyskeratosis congenita autosomal dominant127550C1851970OMIM1188711730187270
HP:0001807HP:0001807Ridged nail0TERT CL E G H7015127550Dyskeratosis congenita autosomal dominant127550C1851970OMIM1160611730187270
HP:0001807HP:0001807Ridged nail0TINF2 CL E G H26277127550Dyskeratosis congenita autosomal dominant127550C1851970OMIM128811824604319
HP:0001807HP:0001807Ridged nail0TINF2 CL E G H26277127550Dyskeratosis congenita autosomal dominant127550C1851970OMIM123011824604319
HP:0001807HP:0001807Ridged nail0WNT10A CL E G H80326224750Schopf-Schulz-Passarge syndrome224750C1857069OMIM130913829606268
HP:0001807HP:0001807Ridged nail0WNT10A CL E G H80326224750Schopf-Schulz-Passarge syndrome224750C1857069OMIM129113829606268
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0001807HP:0001807Ridged nail0ATR CL E G H545614564Cutaneous telangiectasia and cancer syndrome, familial614564C3281203OMIM01007882601215
HP:0001807HP:0001807Ridged nail0ATR CL E G H545614564Cutaneous telangiectasia and cancer syndrome, familial614564C3281203OMIM0755882601215
HP:0001807HP:0001807Ridged nail0LPAR6 CL E G H10161278150Hypotrichosis 8278150C1848435OMIM010115520609239
HP:0001807HP:0001807Ridged nail0LPAR6 CL E G H10161278150Hypotrichosis 8278150C1848435OMIM09615520609239


Genes (18) :ATP2A2 ATR CTSK DKC1 EFNB1 FERMT1 FOXN1 IKBKG KRT14 KRT5 LMX1B LPAR6 MSX1 SLC39A4 TERC TERT TINF2 WNT10A

Diseases (19) :101900 124200 614564 763 265800 305000 304110 173650 169095 601705 308300 601001 2614 161200 278150 189500 37 127550 224750
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.