Human Phenotype Ontology 
Grandparent Node:
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Abnormality of the nail (HP:0001597)help
Parent Node:
expand
Nail dysplasia (HP:0002164)help
..Starting node
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Hyperconvex nail (HP:0001795)help
Term ID: 1795
Name: Hyperconvex nail
Synonym: Increased nail curvature; Nail overcurvature
Definition: When viewed on end (with the digit tip pointing toward the examiner's eye) the curve of the nail forms a tighter curve of convexity.
Comments:
Reference: HP:0001795
Genes and Diseases:
 
       Child Nodes:
........expandHyperconvex fingernails (HP:0001812) help
........expandHyperconvex thumb nails (HP:0008407) help
........expandHyperconvex toenail (HP:0030055) help

 Sister Nodes: 
..expandBifid nail (HP:0010793) help
..expandBroad nail (HP:0001821) help
..expandConcave nail (HP:0001598) help
..expandCongenital onychodystrophy (HP:0008394) help
..expandDeep-set nails (HP:0001814) help
..expandFingernail dysplasia (HP:0100798) help
..expandFused nails (HP:0011312) help
..expandNail pits (HP:0001803) help
..expandNarrow nail (HP:0011313) help
..expandPlatonychia (HP:0030803) help
..expandRidged nail (HP:0001807) help
..expandSplit nail (HP:0001809) help
..expandToenail dysplasia (HP:0100797) help
..expandTrachyonychia (HP:0030804) help
InputHPO IDHPO termDistanceGeneGene id entrezDiseaseIdDiseaseNameDiseaseMIMConceptIDSourceTypical associationHGMD variantsClinVar variantsHGNC IDGeneMIM
 
HPO disease - gene - phenotype typical associations:
HP:0001795HP:0001795Hyperconvex nail0ARX CL E G H170302300004Proud Levine Carpenter syndrome300004C0796124OMIM156518060300382
HP:0001795HP:0001795Hyperconvex nail0ARX CL E G H170302300004Proud Levine Carpenter syndrome300004C0796124OMIM162418060300382
HP:0001795HP:0001795Hyperconvex nail0ECE1 CL E G H1889613870Hirschsprung disease, cardiac defects, and autonomic dysfunction613870C3151237OMIM1513146600423
HP:0001795HP:0001795Hyperconvex nail0ECE1 CL E G H1889613870Hirschsprung disease, cardiac defects, and autonomic dysfunction613870C3151237OMIM1523146600423
HP:0001795HP:0001795Hyperconvex nail0GJB6 CL E G H10804189Elliott Ludman Teebi syndromeORPHA12144288604418
HP:0001795HP:0001795Hyperconvex nail0GJB6 CL E G H10804189Elliott Ludman Teebi syndromeORPHA12234288604418
HP:0001795HP:0001795Hyperconvex nail0ORC1 CL E G H4998224690Meier-Gorlin syndrome 1224690CN030358OMIM11448487601902
HP:0001795HP:0001795Hyperconvex nail0ORC1 CL E G H4998224690Meier-Gorlin syndrome 1224690CN030358OMIM11918487601902
HP:0001795HP:0001795Hyperconvex nail0PIGV CL E G H55650239300Hyperphosphatasia with mental retardation syndrome 1239300CN030519OMIM113126031610274
HP:0001795HP:0001795Hyperconvex nail0PIGV CL E G H55650239300Hyperphosphatasia with mental retardation syndrome 1239300CN030519OMIM120126031610274
HP:0001795HP:0001795Hyperconvex nail0POMP CL E G H51371601952Keratosis linearis with ichthyosis congenita and sclerosing keratoderma601952C1866029OMIM14920330613386
HP:0001795HP:0001795Hyperconvex nail0POMP CL E G H51371601952Keratosis linearis with ichthyosis congenita and sclerosing keratoderma601952C1866029OMIM17120330613386
HP:0001795HP:0001795Hyperconvex nail0SETBP1 CL E G H26040269150Schinzel-Giedion syndrome269150C0265227OMIM132815573611060
HP:0001795HP:0001795Hyperconvex nail0SETBP1 CL E G H26040269150Schinzel-Giedion syndrome269150C0265227OMIM156015573611060
HP:0001795HP:0001795Hyperconvex nail0TP63 CL E G H8626106260Hay-Wells syndrome of ectodermal dysplasia106260C0406709OMIM137615979603273
HP:0001795HP:0001795Hyperconvex nail0TP63 CL E G H8626106260Hay-Wells syndrome of ectodermal dysplasia106260C0406709OMIM144415979603273
HP:0001795HP:0008407Hyperconvex thumb nails1ARX CL E G H170302300004Proud Levine Carpenter syndrome300004C0796124OMIM156518060300382
HP:0001795HP:0001812Hyperconvex fingernails1ARX CL E G H170302300004Proud Levine Carpenter syndrome300004C0796124OMIM162418060300382
HP:0001795HP:0030055Hyperconvex toenail1ARX CL E G H170302300004Proud Levine Carpenter syndrome300004C0796124OMIM162418060300382
HP:0001795HP:0001812Hyperconvex fingernails1ARX CL E G H170302300004Proud Levine Carpenter syndrome300004C0796124OMIM156518060300382
HP:0001795HP:0030055Hyperconvex toenail1ARX CL E G H170302300004Proud Levine Carpenter syndrome300004C0796124OMIM156518060300382
HP:0001795HP:0008407Hyperconvex thumb nails1ARX CL E G H170302300004Proud Levine Carpenter syndrome300004C0796124OMIM162418060300382
HP:0001795HP:0008407Hyperconvex thumb nails1ECE1 CL E G H1889613870Hirschsprung disease, cardiac defects, and autonomic dysfunction613870C3151237OMIM1513146600423
HP:0001795HP:0001812Hyperconvex fingernails1ECE1 CL E G H1889613870Hirschsprung disease, cardiac defects, and autonomic dysfunction613870C3151237OMIM1523146600423
HP:0001795HP:0030055Hyperconvex toenail1ECE1 CL E G H1889613870Hirschsprung disease, cardiac defects, and autonomic dysfunction613870C3151237OMIM1523146600423
HP:0001795HP:0001812Hyperconvex fingernails1ECE1 CL E G H1889613870Hirschsprung disease, cardiac defects, and autonomic dysfunction613870C3151237OMIM1513146600423
HP:0001795HP:0030055Hyperconvex toenail1ECE1 CL E G H1889613870Hirschsprung disease, cardiac defects, and autonomic dysfunction613870C3151237OMIM1513146600423
HP:0001795HP:0008407Hyperconvex thumb nails1ECE1 CL E G H1889613870Hirschsprung disease, cardiac defects, and autonomic dysfunction613870C3151237OMIM1523146600423
HP:0001795HP:0008407Hyperconvex thumb nails1GJB6 CL E G H10804189Elliott Ludman Teebi syndromeORPHA12144288604418
HP:0001795HP:0001812Hyperconvex fingernails1GJB6 CL E G H10804189Elliott Ludman Teebi syndromeORPHA12234288604418
HP:0001795HP:0030055Hyperconvex toenail1GJB6 CL E G H10804189Elliott Ludman Teebi syndromeORPHA12234288604418
HP:0001795HP:0001812Hyperconvex fingernails1GJB6 CL E G H10804189Elliott Ludman Teebi syndromeORPHA12144288604418
HP:0001795HP:0030055Hyperconvex toenail1GJB6 CL E G H10804189Elliott Ludman Teebi syndromeORPHA12144288604418
HP:0001795HP:0008407Hyperconvex thumb nails1GJB6 CL E G H10804189Elliott Ludman Teebi syndromeORPHA12234288604418
HP:0001795HP:0008407Hyperconvex thumb nails1ORC1 CL E G H4998224690Meier-Gorlin syndrome 1224690CN030358OMIM11448487601902
HP:0001795HP:0001812Hyperconvex fingernails1ORC1 CL E G H4998224690Meier-Gorlin syndrome 1224690CN030358OMIM11918487601902
HP:0001795HP:0030055Hyperconvex toenail1ORC1 CL E G H4998224690Meier-Gorlin syndrome 1224690CN030358OMIM11918487601902
HP:0001795HP:0001812Hyperconvex fingernails1ORC1 CL E G H4998224690Meier-Gorlin syndrome 1224690CN030358OMIM11448487601902
HP:0001795HP:0030055Hyperconvex toenail1ORC1 CL E G H4998224690Meier-Gorlin syndrome 1224690CN030358OMIM11448487601902
HP:0001795HP:0008407Hyperconvex thumb nails1ORC1 CL E G H4998224690Meier-Gorlin syndrome 1224690CN030358OMIM11918487601902
HP:0001795HP:0008407Hyperconvex thumb nails1PIGV CL E G H55650239300Hyperphosphatasia with mental retardation syndrome 1239300CN030519OMIM113126031610274
HP:0001795HP:0001812Hyperconvex fingernails1PIGV CL E G H55650239300Hyperphosphatasia with mental retardation syndrome 1239300CN030519OMIM120126031610274
HP:0001795HP:0030055Hyperconvex toenail1PIGV CL E G H55650239300Hyperphosphatasia with mental retardation syndrome 1239300CN030519OMIM120126031610274
HP:0001795HP:0001812Hyperconvex fingernails1PIGV CL E G H55650239300Hyperphosphatasia with mental retardation syndrome 1239300CN030519OMIM113126031610274
HP:0001795HP:0030055Hyperconvex toenail1PIGV CL E G H55650239300Hyperphosphatasia with mental retardation syndrome 1239300CN030519OMIM113126031610274
HP:0001795HP:0008407Hyperconvex thumb nails1PIGV CL E G H55650239300Hyperphosphatasia with mental retardation syndrome 1239300CN030519OMIM120126031610274
HP:0001795HP:0008407Hyperconvex thumb nails1POMP CL E G H51371601952Keratosis linearis with ichthyosis congenita and sclerosing keratoderma601952C1866029OMIM14920330613386
HP:0001795HP:0030055Hyperconvex toenail1POMP CL E G H51371601952Keratosis linearis with ichthyosis congenita and sclerosing keratoderma601952C1866029OMIM17120330613386
HP:0001795HP:0001812Hyperconvex fingernails1POMP CL E G H51371601952Keratosis linearis with ichthyosis congenita and sclerosing keratoderma601952C1866029OMIM17120330613386
HP:0001795HP:0030055Hyperconvex toenail1POMP CL E G H51371601952Keratosis linearis with ichthyosis congenita and sclerosing keratoderma601952C1866029OMIM14920330613386
HP:0001795HP:0001812Hyperconvex fingernails1POMP CL E G H51371601952Keratosis linearis with ichthyosis congenita and sclerosing keratoderma601952C1866029OMIM14920330613386
HP:0001795HP:0008407Hyperconvex thumb nails1POMP CL E G H51371601952Keratosis linearis with ichthyosis congenita and sclerosing keratoderma601952C1866029OMIM17120330613386
HP:0001795HP:0008407Hyperconvex thumb nails1SETBP1 CL E G H26040269150Schinzel-Giedion syndrome269150C0265227OMIM132815573611060
HP:0001795HP:0001812Hyperconvex fingernails1SETBP1 CL E G H26040269150Schinzel-Giedion syndrome269150C0265227OMIM156015573611060
HP:0001795HP:0030055Hyperconvex toenail1SETBP1 CL E G H26040269150Schinzel-Giedion syndrome269150C0265227OMIM156015573611060
HP:0001795HP:0030055Hyperconvex toenail1SETBP1 CL E G H26040269150Schinzel-Giedion syndrome269150C0265227OMIM132815573611060
HP:0001795HP:0001812Hyperconvex fingernails1SETBP1 CL E G H26040269150Schinzel-Giedion syndrome269150C0265227OMIM132815573611060
HP:0001795HP:0008407Hyperconvex thumb nails1SETBP1 CL E G H26040269150Schinzel-Giedion syndrome269150C0265227OMIM156015573611060
HP:0001795HP:0008407Hyperconvex thumb nails1TP63 CL E G H8626106260Hay-Wells syndrome of ectodermal dysplasia106260C0406709OMIM137615979603273
HP:0001795HP:0001812Hyperconvex fingernails1TP63 CL E G H8626106260Hay-Wells syndrome of ectodermal dysplasia106260C0406709OMIM144415979603273
HP:0001795HP:0030055Hyperconvex toenail1TP63 CL E G H8626106260Hay-Wells syndrome of ectodermal dysplasia106260C0406709OMIM144415979603273
HP:0001795HP:0001812Hyperconvex fingernails1TP63 CL E G H8626106260Hay-Wells syndrome of ectodermal dysplasia106260C0406709OMIM137615979603273
HP:0001795HP:0030055Hyperconvex toenail1TP63 CL E G H8626106260Hay-Wells syndrome of ectodermal dysplasia106260C0406709OMIM137615979603273
HP:0001795HP:0008407Hyperconvex thumb nails1TP63 CL E G H8626106260Hay-Wells syndrome of ectodermal dysplasia106260C0406709OMIM144415979603273
 
HPO disease - gene - phenotype less frequent non-typical associations:


Genes (18) :ARX CPLX1 CTBP1 ECE1 FGFRL1 GJB6 LETM1 MBTPS2 NSD2 ORC1 PIGV PLEC POMP PTDSS1 RPS6KA3 SETBP1 TP63 WHCR

Diseases (15) :300004 613870 189 224690 239300 601952 269150 106260 194190 2273 257 2658 303600 192 1071
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.