Human Phenotype Ontology 
Grandparent Node:
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Phenotypic abnormality (HP:0000118)help
Parent Node:
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Abnormality of the voice (HP:0001608)help
..Starting node
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Loss of voice (HP:0001686)help
Term ID: 1686
Name: Loss of voice
Synonym: Aphonia
Definition:
Comments:
Reference: HP:0001686
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAbnormal cry (HP:0025429) help
..expandAbnormal speech prosody (HP:0031434) help
..expandAbnormally low-pitched voice (HP:0010300) help
..expandDysphonia (HP:0001618) help
..expandHigh pitched voice (HP:0001620) help
..expandHoarse voice (HP:0001609) help
..expandHyponasal speech (HP:0100271) help
..expandNasal speech (HP:0001611) help
..expandSpeech articulation difficulties (HP:0009088) help
..expandVocal cord dysfunction (HP:0031801) help
..expandWeak voice (HP:0001621) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0001686HP:0001686Loss of voice0ASAH1 CL E G H427735ORPHA:333Farber diseaseHP:0040284 - Very rare78
HP:0001686HP:0001686Loss of voice0FTL CL E G H25123999ORPHA:157846NeuroferritinopathyHP:0040283 - Occasional33
HP:0001686HP:0001686Loss of voice0SDHA CL E G H638910680OMIM:619259NEURODEGENERATION WITH ATAXIA AND LATE-ONSET OPTIC ATROPHY; NDAXOA304
HP:0001686HP:0001686Loss of voice0SDHAF2 CL E G H5494926034OMIM:601650Paragangliomas 2.55
HP:0001686HP:0001686Loss of voice0SDHC CL E G H639110682OMIM:605373Paragangliomas 3.147
HP:0001686HP:0001686Loss of voice0SDHD CL E G H639210683OMIM:168000Paragangliomas 1.129


Genes (6) :ASAH1 FTL SDHA SDHAF2 SDHC SDHD

Diseases (6) :ORPHA:333 ORPHA:157846 OMIM:619259 OMIM:601650 OMIM:605373 OMIM:168000
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.