Human Phenotype Ontology 
Grandparent Node:
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Mode of inheritance (HP:0000005)help
Parent Node:
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Autosomal dominant inheritance (HP:0000006)help
..Starting node
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Sex-limited expression (HP:0001470)help
Term ID: 1470
Name: Sex-limited expression
Synonym:
Definition: Sex limitation is used to refer to a monogenic trait linked to an autosomal locus in which the phenotypic effects of allelic differences are expressed only in one sex.
Comments:
Reference: HP:0001470
Genes and Diseases:
 
       Child Nodes:
........expandMale-limited autosomal dominant (HP:0001475) help

 Sister Nodes: 
..expandAutosomal dominant inheritance with maternal imprinting (HP:0012275) help
..expandAutosomal dominant inheritance with paternal imprinting (HP:0012274) help
..expandAutosomal dominant somatic cell mutation (HP:0001444) help
..expandobsolete Autosomal dominant contiguous gene syndrome (HP:0001452) help
..expandTypically de novo (HP:0025352) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0001470HP:0001470Sex-limited expression0FIGLA CL E G H34401824669OMIM:612310PREMATURE OVARIAN FAILURE 6; POF617
HP:0001470HP:0001470Sex-limited expression0LHCGR CL E G H39736585OMIM:176410Precocious puberty, male67
HP:0001470HP:0001470Sex-limited expression0NR5A1 CL E G H25167983OMIM:61296546XY sex reversal 338
HP:0001470HP:0001470Sex-limited expression0NR5A1 CL E G H25167983OMIM:612964PREMATURE OVARIAN FAILURE 7; POF738
HP:0001470HP:0001470Sex-limited expression0POF1B CL E G H7998313711OMIM:300604Premature ovarian failure 2B31
HP:0001470HP:0001475Male-limited expression1 CL E G H
HP:0001470HP:0034344Female-limited expression1POF1B CL E G H7998313711OMIM:300604Premature ovarian failure 2B31


Genes (4) :FIGLA LHCGR NR5A1 POF1B

Diseases (5) :OMIM:612310 OMIM:176410 OMIM:612965 OMIM:612964 OMIM:300604
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.