Human Phenotype Ontology 
Grandparent Node:
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Abnormal digit morphology (HP:0011297)help
Parent Node:
expand
Syndactyly (HP:0001159)help
..Starting node
..expand
Cutaneous syndactyly (HP:0012725)help
Term ID: 12725
Name: Cutaneous syndactyly
Synonym: Cutaneous syndactyly of digits; Syndactyly, cutaneous
Definition: A soft tissue continuity in the A/P axis between two digits that extends distally to at least the level of the proximal interphalangeal joints, or a soft tissue continuity in the A/P axis between two digits that lies significantly distal to the flexion crease that overlies the metacarpophalangeal or metatarsophalangeal joint of the adjacent digits.
Comments:
Reference: HP:0012725
Genes and Diseases:
 
       Child Nodes:
........expandCutaneous finger syndactyly (HP:0010554) help
................... HP:0005650 Cutaneous syndactyly between fingers 2 and 5
................... HP:0006088 1-5 finger complete cutaneous syndactyly
................... HP:0011939 3-4 finger cutaneous syndactyly
........expandCutaneous syndactyly of toes (HP:0010621) help
................... HP:0005709 2-3 toe cutaneous syndactyly
................... HP:0005767 1-2 toe complete cutaneous syndactyly
................... HP:0005768 2-4 toe cutaneous syndactyly

 Sister Nodes: 
..expandFinger syndactyly (HP:0006101) help
..expandToe syndactyly (HP:0001770) help
InputHPO IDHPO termDistanceGeneGene id entrezDiseaseIdDiseaseNameDiseaseMIMConceptIDSourceTypical associationHGMD variantsClinVar variantsHGNC IDGeneMIM
 
HPO disease - gene - phenotype typical associations:
HP:0012725HP:0012725Cutaneous syndactyly0ANKRD11 CL E G H291232332ORPHA1118421316611192
HP:0012725HP:0012725Cutaneous syndactyly0ANKRD11 CL E G H291232332ORPHA1110121316611192
HP:0012725HP:0012725Cutaneous syndactyly0BHLHA9 CL E G H727857607539Camptosynpolydactyly, complex607539C1843758OMIM114135126615416
HP:0012725HP:0012725Cutaneous syndactyly0BHLHA9 CL E G H727857607539Camptosynpolydactyly, complex607539C1843758OMIM113135126615416
HP:0012725HP:0012725Cutaneous syndactyly0CACNA1C CL E G H775601005Timothy syndrome601005C1832916OMIM118301390114205
HP:0012725HP:0012725Cutaneous syndactyly0CACNA1C CL E G H775601005Timothy syndrome601005C1832916OMIM116581390114205
HP:0012725HP:0012725Cutaneous syndactyly0CKAP2L CL E G H150468272440Filippi syndrome272440C0795940OMIM19426877616174
HP:0012725HP:0012725Cutaneous syndactyly0CKAP2L CL E G H150468272440Filippi syndrome272440C0795940OMIM17826877616174
HP:0012725HP:0012725Cutaneous syndactyly0GRIP1 CL E G H23426617667FRASER SYNDROME 3617667C4540040OMIM116418708604597
HP:0012725HP:0012725Cutaneous syndactyly0GRIP1 CL E G H23426617667FRASER SYNDROME 3617667C4540040OMIM116118708604597
HP:0012725HP:0012725Cutaneous syndactyly0KIAA1109 CL E G H84162617822ALKURAYA-KUCINSKAS SYNDROME617822CN737163OMIM123226953611565
HP:0012725HP:0012725Cutaneous syndactyly0KIAA1109 CL E G H84162617822ALKURAYA-KUCINSKAS SYNDROME617822CN737163OMIM122326953611565
HP:0012725HP:0012725Cutaneous syndactyly0MAP3K20 CL E G H51776616890Split-foot malformation with mesoaxial polydactyly616890C4225167OMIM116217797609479
HP:0012725HP:0012725Cutaneous syndactyly0MAP3K20 CL E G H51776616890Split-foot malformation with mesoaxial polydactyly616890C4225167OMIM17617797609479
HP:0012725HP:0012725Cutaneous syndactyly0MEIS2 CL E G H4212600987Cleft palate, cardiac defects, and mental retardation600987C1832950OMIM1807001601740
HP:0012725HP:0012725Cutaneous syndactyly0MEIS2 CL E G H4212600987Cleft palate, cardiac defects, and mental retardation600987C1832950OMIM1717001601740
HP:0012725HP:0012725Cutaneous syndactyly0RBM10 CL E G H8241311900TARP syndrome311900C1839463OMIM12249896300080
HP:0012725HP:0012725Cutaneous syndactyly0RBM10 CL E G H8241311900TARP syndrome311900C1839463OMIM12209896300080
HP:0012725HP:0012725Cutaneous syndactyly0TMEM94 CL E G H9772618316618316618316OMIM15328983618163
HP:0012725HP:0012725Cutaneous syndactyly0TMEM94 CL E G H9772618316618316618316OMIM14628983618163
HP:0012725HP:0012725Cutaneous syndactyly0TWIST1 CL E G H7291617746SWEENEY-COX SYNDROME617746C4540299OMIM116312428601622
HP:0012725HP:0012725Cutaneous syndactyly0TWIST1 CL E G H7291617746SWEENEY-COX SYNDROME617746C4540299OMIM114212428601622
HP:0012725HP:0010621Cutaneous syndactyly of toes1ANKRD11 CL E G H291232332ORPHA1118421316611192
HP:0012725HP:0010554Cutaneous finger syndactyly1ANKRD11 CL E G H291232332ORPHA1118421316611192
HP:0012725HP:0010621Cutaneous syndactyly of toes1ANKRD11 CL E G H291232332ORPHA1110121316611192
HP:0012725HP:0010554Cutaneous finger syndactyly1ANKRD11 CL E G H291232332ORPHA1110121316611192
HP:0012725HP:0010621Cutaneous syndactyly of toes1BHLHA9 CL E G H727857607539Camptosynpolydactyly, complex607539C1843758OMIM114135126615416
HP:0012725HP:0010554Cutaneous finger syndactyly1BHLHA9 CL E G H727857607539Camptosynpolydactyly, complex607539C1843758OMIM114135126615416
HP:0012725HP:0010621Cutaneous syndactyly of toes1BHLHA9 CL E G H727857607539Camptosynpolydactyly, complex607539C1843758OMIM113135126615416
HP:0012725HP:0010554Cutaneous finger syndactyly1BHLHA9 CL E G H727857607539Camptosynpolydactyly, complex607539C1843758OMIM113135126615416
HP:0012725HP:0010621Cutaneous syndactyly of toes1CACNA1C CL E G H775601005Timothy syndrome601005C1832916OMIM118301390114205
HP:0012725HP:0010554Cutaneous finger syndactyly1CACNA1C CL E G H775601005Timothy syndrome601005C1832916OMIM118301390114205
HP:0012725HP:0010621Cutaneous syndactyly of toes1CACNA1C CL E G H775601005Timothy syndrome601005C1832916OMIM116581390114205
HP:0012725HP:0010554Cutaneous finger syndactyly1CACNA1C CL E G H775601005Timothy syndrome601005C1832916OMIM116581390114205
HP:0012725HP:0010621Cutaneous syndactyly of toes1CKAP2L CL E G H150468272440Filippi syndrome272440C0795940OMIM19426877616174
HP:0012725HP:0010554Cutaneous finger syndactyly1CKAP2L CL E G H150468272440Filippi syndrome272440C0795940OMIM19426877616174
HP:0012725HP:0010621Cutaneous syndactyly of toes1CKAP2L CL E G H150468272440Filippi syndrome272440C0795940OMIM17826877616174
HP:0012725HP:0010554Cutaneous finger syndactyly1CKAP2L CL E G H150468272440Filippi syndrome272440C0795940OMIM17826877616174
HP:0012725HP:0010621Cutaneous syndactyly of toes1GRIP1 CL E G H23426617667FRASER SYNDROME 3617667C4540040OMIM116418708604597
HP:0012725HP:0010554Cutaneous finger syndactyly1GRIP1 CL E G H23426617667FRASER SYNDROME 3617667C4540040OMIM116418708604597
HP:0012725HP:0010621Cutaneous syndactyly of toes1GRIP1 CL E G H23426617667FRASER SYNDROME 3617667C4540040OMIM116118708604597
HP:0012725HP:0010554Cutaneous finger syndactyly1GRIP1 CL E G H23426617667FRASER SYNDROME 3617667C4540040OMIM116118708604597
HP:0012725HP:0010621Cutaneous syndactyly of toes1KIAA1109 CL E G H84162617822ALKURAYA-KUCINSKAS SYNDROME617822CN737163OMIM123226953611565
HP:0012725HP:0010554Cutaneous finger syndactyly1KIAA1109 CL E G H84162617822ALKURAYA-KUCINSKAS SYNDROME617822CN737163OMIM123226953611565
HP:0012725HP:0010621Cutaneous syndactyly of toes1KIAA1109 CL E G H84162617822ALKURAYA-KUCINSKAS SYNDROME617822CN737163OMIM122326953611565
HP:0012725HP:0010554Cutaneous finger syndactyly1KIAA1109 CL E G H84162617822ALKURAYA-KUCINSKAS SYNDROME617822CN737163OMIM122326953611565
HP:0012725HP:0010621Cutaneous syndactyly of toes1MAP3K20 CL E G H51776616890Split-foot malformation with mesoaxial polydactyly616890C4225167OMIM116217797609479
HP:0012725HP:0010554Cutaneous finger syndactyly1MAP3K20 CL E G H51776616890Split-foot malformation with mesoaxial polydactyly616890C4225167OMIM116217797609479
HP:0012725HP:0010621Cutaneous syndactyly of toes1MAP3K20 CL E G H51776616890Split-foot malformation with mesoaxial polydactyly616890C4225167OMIM17617797609479
HP:0012725HP:0010554Cutaneous finger syndactyly1MAP3K20 CL E G H51776616890Split-foot malformation with mesoaxial polydactyly616890C4225167OMIM17617797609479
HP:0012725HP:0010621Cutaneous syndactyly of toes1MEIS2 CL E G H4212600987Cleft palate, cardiac defects, and mental retardation600987C1832950OMIM1807001601740
HP:0012725HP:0010554Cutaneous finger syndactyly1MEIS2 CL E G H4212600987Cleft palate, cardiac defects, and mental retardation600987C1832950OMIM1807001601740
HP:0012725HP:0010621Cutaneous syndactyly of toes1MEIS2 CL E G H4212600987Cleft palate, cardiac defects, and mental retardation600987C1832950OMIM1717001601740
HP:0012725HP:0010554Cutaneous finger syndactyly1MEIS2 CL E G H4212600987Cleft palate, cardiac defects, and mental retardation600987C1832950OMIM1717001601740
HP:0012725HP:0010621Cutaneous syndactyly of toes1RBM10 CL E G H8241311900TARP syndrome311900C1839463OMIM12249896300080
HP:0012725HP:0010554Cutaneous finger syndactyly1RBM10 CL E G H8241311900TARP syndrome311900C1839463OMIM12249896300080
HP:0012725HP:0010621Cutaneous syndactyly of toes1RBM10 CL E G H8241311900TARP syndrome311900C1839463OMIM12209896300080
HP:0012725HP:0010554Cutaneous finger syndactyly1RBM10 CL E G H8241311900TARP syndrome311900C1839463OMIM12209896300080
HP:0012725HP:0010621Cutaneous syndactyly of toes1TMEM94 CL E G H9772618316618316618316OMIM15328983618163
HP:0012725HP:0010554Cutaneous finger syndactyly1TMEM94 CL E G H9772618316618316618316OMIM15328983618163
HP:0012725HP:0010621Cutaneous syndactyly of toes1TMEM94 CL E G H9772618316618316618316OMIM14628983618163
HP:0012725HP:0010554Cutaneous finger syndactyly1TMEM94 CL E G H9772618316618316618316OMIM14628983618163
HP:0012725HP:0010621Cutaneous syndactyly of toes1TWIST1 CL E G H7291617746SWEENEY-COX SYNDROME617746C4540299OMIM116312428601622
HP:0012725HP:0010554Cutaneous finger syndactyly1TWIST1 CL E G H7291617746SWEENEY-COX SYNDROME617746C4540299OMIM116312428601622
HP:0012725HP:0010621Cutaneous syndactyly of toes1TWIST1 CL E G H7291617746SWEENEY-COX SYNDROME617746C4540299OMIM114212428601622
HP:0012725HP:0010554Cutaneous finger syndactyly1TWIST1 CL E G H7291617746SWEENEY-COX SYNDROME617746C4540299OMIM114212428601622
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2ANKRD11 CL E G H291232332ORPHA1118421316611192
HP:0012725HP:00057682-4 toe cutaneous syndactyly2ANKRD11 CL E G H291232332ORPHA1118421316611192
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2ANKRD11 CL E G H291232332ORPHA1118421316611192
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52ANKRD11 CL E G H291232332ORPHA1118421316611192
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2ANKRD11 CL E G H291232332ORPHA1110121316611192
HP:0012725HP:00057682-4 toe cutaneous syndactyly2ANKRD11 CL E G H291232332ORPHA1110121316611192
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2ANKRD11 CL E G H291232332ORPHA1110121316611192
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52ANKRD11 CL E G H291232332ORPHA1110121316611192
HP:0012725HP:00057092-3 toe cutaneous syndactyly2ANKRD11 CL E G H291232332ORPHA1118421316611192
HP:0012725HP:00119393-4 finger cutaneous syndactyly2ANKRD11 CL E G H291232332ORPHA1118421316611192
HP:0012725HP:00057092-3 toe cutaneous syndactyly2ANKRD11 CL E G H291232332ORPHA1110121316611192
HP:0012725HP:00119393-4 finger cutaneous syndactyly2ANKRD11 CL E G H291232332ORPHA1110121316611192
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52BHLHA9 CL E G H727857607539Camptosynpolydactyly, complex607539C1843758OMIM114135126615416
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2BHLHA9 CL E G H727857607539Camptosynpolydactyly, complex607539C1843758OMIM114135126615416
HP:0012725HP:00057682-4 toe cutaneous syndactyly2BHLHA9 CL E G H727857607539Camptosynpolydactyly, complex607539C1843758OMIM114135126615416
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2BHLHA9 CL E G H727857607539Camptosynpolydactyly, complex607539C1843758OMIM114135126615416
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52BHLHA9 CL E G H727857607539Camptosynpolydactyly, complex607539C1843758OMIM113135126615416
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2BHLHA9 CL E G H727857607539Camptosynpolydactyly, complex607539C1843758OMIM113135126615416
HP:0012725HP:00057682-4 toe cutaneous syndactyly2BHLHA9 CL E G H727857607539Camptosynpolydactyly, complex607539C1843758OMIM113135126615416
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2BHLHA9 CL E G H727857607539Camptosynpolydactyly, complex607539C1843758OMIM113135126615416
HP:0012725HP:00119393-4 finger cutaneous syndactyly2BHLHA9 CL E G H727857607539Camptosynpolydactyly, complex607539C1843758OMIM114135126615416
HP:0012725HP:00057092-3 toe cutaneous syndactyly2BHLHA9 CL E G H727857607539Camptosynpolydactyly, complex607539C1843758OMIM114135126615416
HP:0012725HP:00057092-3 toe cutaneous syndactyly2BHLHA9 CL E G H727857607539Camptosynpolydactyly, complex607539C1843758OMIM113135126615416
HP:0012725HP:00119393-4 finger cutaneous syndactyly2BHLHA9 CL E G H727857607539Camptosynpolydactyly, complex607539C1843758OMIM113135126615416
HP:0012725HP:00119393-4 finger cutaneous syndactyly2CACNA1C CL E G H775601005Timothy syndrome601005C1832916OMIM118301390114205
HP:0012725HP:00057092-3 toe cutaneous syndactyly2CACNA1C CL E G H775601005Timothy syndrome601005C1832916OMIM118301390114205
HP:0012725HP:00119393-4 finger cutaneous syndactyly2CACNA1C CL E G H775601005Timothy syndrome601005C1832916OMIM116581390114205
HP:0012725HP:00057092-3 toe cutaneous syndactyly2CACNA1C CL E G H775601005Timothy syndrome601005C1832916OMIM116581390114205
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52CACNA1C CL E G H775601005Timothy syndrome601005C1832916OMIM118301390114205
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2CACNA1C CL E G H775601005Timothy syndrome601005C1832916OMIM118301390114205
HP:0012725HP:00057682-4 toe cutaneous syndactyly2CACNA1C CL E G H775601005Timothy syndrome601005C1832916OMIM118301390114205
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2CACNA1C CL E G H775601005Timothy syndrome601005C1832916OMIM118301390114205
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52CACNA1C CL E G H775601005Timothy syndrome601005C1832916OMIM116581390114205
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2CACNA1C CL E G H775601005Timothy syndrome601005C1832916OMIM116581390114205
HP:0012725HP:00057682-4 toe cutaneous syndactyly2CACNA1C CL E G H775601005Timothy syndrome601005C1832916OMIM116581390114205
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2CACNA1C CL E G H775601005Timothy syndrome601005C1832916OMIM116581390114205
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2CKAP2L CL E G H150468272440Filippi syndrome272440C0795940OMIM19426877616174
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52CKAP2L CL E G H150468272440Filippi syndrome272440C0795940OMIM19426877616174
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2CKAP2L CL E G H150468272440Filippi syndrome272440C0795940OMIM19426877616174
HP:0012725HP:00057682-4 toe cutaneous syndactyly2CKAP2L CL E G H150468272440Filippi syndrome272440C0795940OMIM19426877616174
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2CKAP2L CL E G H150468272440Filippi syndrome272440C0795940OMIM17826877616174
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52CKAP2L CL E G H150468272440Filippi syndrome272440C0795940OMIM17826877616174
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2CKAP2L CL E G H150468272440Filippi syndrome272440C0795940OMIM17826877616174
HP:0012725HP:00057682-4 toe cutaneous syndactyly2CKAP2L CL E G H150468272440Filippi syndrome272440C0795940OMIM17826877616174
HP:0012725HP:00119393-4 finger cutaneous syndactyly2CKAP2L CL E G H150468272440Filippi syndrome272440C0795940OMIM19426877616174
HP:0012725HP:00057092-3 toe cutaneous syndactyly2CKAP2L CL E G H150468272440Filippi syndrome272440C0795940OMIM19426877616174
HP:0012725HP:00119393-4 finger cutaneous syndactyly2CKAP2L CL E G H150468272440Filippi syndrome272440C0795940OMIM17826877616174
HP:0012725HP:00057092-3 toe cutaneous syndactyly2CKAP2L CL E G H150468272440Filippi syndrome272440C0795940OMIM17826877616174
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52GRIP1 CL E G H23426617667FRASER SYNDROME 3617667C4540040OMIM116418708604597
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2GRIP1 CL E G H23426617667FRASER SYNDROME 3617667C4540040OMIM116418708604597
HP:0012725HP:00057682-4 toe cutaneous syndactyly2GRIP1 CL E G H23426617667FRASER SYNDROME 3617667C4540040OMIM116418708604597
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2GRIP1 CL E G H23426617667FRASER SYNDROME 3617667C4540040OMIM116418708604597
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52GRIP1 CL E G H23426617667FRASER SYNDROME 3617667C4540040OMIM116118708604597
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2GRIP1 CL E G H23426617667FRASER SYNDROME 3617667C4540040OMIM116118708604597
HP:0012725HP:00057682-4 toe cutaneous syndactyly2GRIP1 CL E G H23426617667FRASER SYNDROME 3617667C4540040OMIM116118708604597
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2GRIP1 CL E G H23426617667FRASER SYNDROME 3617667C4540040OMIM116118708604597
HP:0012725HP:00057092-3 toe cutaneous syndactyly2GRIP1 CL E G H23426617667FRASER SYNDROME 3617667C4540040OMIM116418708604597
HP:0012725HP:00119393-4 finger cutaneous syndactyly2GRIP1 CL E G H23426617667FRASER SYNDROME 3617667C4540040OMIM116418708604597
HP:0012725HP:00057092-3 toe cutaneous syndactyly2GRIP1 CL E G H23426617667FRASER SYNDROME 3617667C4540040OMIM116118708604597
HP:0012725HP:00119393-4 finger cutaneous syndactyly2GRIP1 CL E G H23426617667FRASER SYNDROME 3617667C4540040OMIM116118708604597
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52KIAA1109 CL E G H84162617822ALKURAYA-KUCINSKAS SYNDROME617822CN737163OMIM123226953611565
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2KIAA1109 CL E G H84162617822ALKURAYA-KUCINSKAS SYNDROME617822CN737163OMIM123226953611565
HP:0012725HP:00057682-4 toe cutaneous syndactyly2KIAA1109 CL E G H84162617822ALKURAYA-KUCINSKAS SYNDROME617822CN737163OMIM123226953611565
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2KIAA1109 CL E G H84162617822ALKURAYA-KUCINSKAS SYNDROME617822CN737163OMIM123226953611565
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2KIAA1109 CL E G H84162617822ALKURAYA-KUCINSKAS SYNDROME617822CN737163OMIM122326953611565
HP:0012725HP:00057682-4 toe cutaneous syndactyly2KIAA1109 CL E G H84162617822ALKURAYA-KUCINSKAS SYNDROME617822CN737163OMIM122326953611565
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2KIAA1109 CL E G H84162617822ALKURAYA-KUCINSKAS SYNDROME617822CN737163OMIM122326953611565
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52KIAA1109 CL E G H84162617822ALKURAYA-KUCINSKAS SYNDROME617822CN737163OMIM122326953611565
HP:0012725HP:00057092-3 toe cutaneous syndactyly2KIAA1109 CL E G H84162617822ALKURAYA-KUCINSKAS SYNDROME617822CN737163OMIM123226953611565
HP:0012725HP:00119393-4 finger cutaneous syndactyly2KIAA1109 CL E G H84162617822ALKURAYA-KUCINSKAS SYNDROME617822CN737163OMIM123226953611565
HP:0012725HP:00057092-3 toe cutaneous syndactyly2KIAA1109 CL E G H84162617822ALKURAYA-KUCINSKAS SYNDROME617822CN737163OMIM122326953611565
HP:0012725HP:00119393-4 finger cutaneous syndactyly2KIAA1109 CL E G H84162617822ALKURAYA-KUCINSKAS SYNDROME617822CN737163OMIM122326953611565
HP:0012725HP:00119393-4 finger cutaneous syndactyly2MAP3K20 CL E G H51776616890Split-foot malformation with mesoaxial polydactyly616890C4225167OMIM116217797609479
HP:0012725HP:00057092-3 toe cutaneous syndactyly2MAP3K20 CL E G H51776616890Split-foot malformation with mesoaxial polydactyly616890C4225167OMIM116217797609479
HP:0012725HP:00057092-3 toe cutaneous syndactyly2MAP3K20 CL E G H51776616890Split-foot malformation with mesoaxial polydactyly616890C4225167OMIM17617797609479
HP:0012725HP:00119393-4 finger cutaneous syndactyly2MAP3K20 CL E G H51776616890Split-foot malformation with mesoaxial polydactyly616890C4225167OMIM17617797609479
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52MAP3K20 CL E G H51776616890Split-foot malformation with mesoaxial polydactyly616890C4225167OMIM116217797609479
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2MAP3K20 CL E G H51776616890Split-foot malformation with mesoaxial polydactyly616890C4225167OMIM116217797609479
HP:0012725HP:00057682-4 toe cutaneous syndactyly2MAP3K20 CL E G H51776616890Split-foot malformation with mesoaxial polydactyly616890C4225167OMIM116217797609479
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2MAP3K20 CL E G H51776616890Split-foot malformation with mesoaxial polydactyly616890C4225167OMIM116217797609479
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52MAP3K20 CL E G H51776616890Split-foot malformation with mesoaxial polydactyly616890C4225167OMIM17617797609479
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2MAP3K20 CL E G H51776616890Split-foot malformation with mesoaxial polydactyly616890C4225167OMIM17617797609479
HP:0012725HP:00057682-4 toe cutaneous syndactyly2MAP3K20 CL E G H51776616890Split-foot malformation with mesoaxial polydactyly616890C4225167OMIM17617797609479
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2MAP3K20 CL E G H51776616890Split-foot malformation with mesoaxial polydactyly616890C4225167OMIM17617797609479
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52MEIS2 CL E G H4212600987Cleft palate, cardiac defects, and mental retardation600987C1832950OMIM1807001601740
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2MEIS2 CL E G H4212600987Cleft palate, cardiac defects, and mental retardation600987C1832950OMIM1807001601740
HP:0012725HP:00057682-4 toe cutaneous syndactyly2MEIS2 CL E G H4212600987Cleft palate, cardiac defects, and mental retardation600987C1832950OMIM1807001601740
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2MEIS2 CL E G H4212600987Cleft palate, cardiac defects, and mental retardation600987C1832950OMIM1807001601740
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52MEIS2 CL E G H4212600987Cleft palate, cardiac defects, and mental retardation600987C1832950OMIM1717001601740
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2MEIS2 CL E G H4212600987Cleft palate, cardiac defects, and mental retardation600987C1832950OMIM1717001601740
HP:0012725HP:00057682-4 toe cutaneous syndactyly2MEIS2 CL E G H4212600987Cleft palate, cardiac defects, and mental retardation600987C1832950OMIM1717001601740
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2MEIS2 CL E G H4212600987Cleft palate, cardiac defects, and mental retardation600987C1832950OMIM1717001601740
HP:0012725HP:00119393-4 finger cutaneous syndactyly2MEIS2 CL E G H4212600987Cleft palate, cardiac defects, and mental retardation600987C1832950OMIM1807001601740
HP:0012725HP:00057092-3 toe cutaneous syndactyly2MEIS2 CL E G H4212600987Cleft palate, cardiac defects, and mental retardation600987C1832950OMIM1807001601740
HP:0012725HP:00119393-4 finger cutaneous syndactyly2MEIS2 CL E G H4212600987Cleft palate, cardiac defects, and mental retardation600987C1832950OMIM1717001601740
HP:0012725HP:00057092-3 toe cutaneous syndactyly2MEIS2 CL E G H4212600987Cleft palate, cardiac defects, and mental retardation600987C1832950OMIM1717001601740
HP:0012725HP:00119393-4 finger cutaneous syndactyly2RBM10 CL E G H8241311900TARP syndrome311900C1839463OMIM12249896300080
HP:0012725HP:00057092-3 toe cutaneous syndactyly2RBM10 CL E G H8241311900TARP syndrome311900C1839463OMIM12249896300080
HP:0012725HP:00119393-4 finger cutaneous syndactyly2RBM10 CL E G H8241311900TARP syndrome311900C1839463OMIM12209896300080
HP:0012725HP:00057092-3 toe cutaneous syndactyly2RBM10 CL E G H8241311900TARP syndrome311900C1839463OMIM12209896300080
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2RBM10 CL E G H8241311900TARP syndrome311900C1839463OMIM12249896300080
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52RBM10 CL E G H8241311900TARP syndrome311900C1839463OMIM12249896300080
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2RBM10 CL E G H8241311900TARP syndrome311900C1839463OMIM12249896300080
HP:0012725HP:00057682-4 toe cutaneous syndactyly2RBM10 CL E G H8241311900TARP syndrome311900C1839463OMIM12249896300080
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52RBM10 CL E G H8241311900TARP syndrome311900C1839463OMIM12209896300080
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2RBM10 CL E G H8241311900TARP syndrome311900C1839463OMIM12209896300080
HP:0012725HP:00057682-4 toe cutaneous syndactyly2RBM10 CL E G H8241311900TARP syndrome311900C1839463OMIM12209896300080
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2RBM10 CL E G H8241311900TARP syndrome311900C1839463OMIM12209896300080
HP:0012725HP:00057092-3 toe cutaneous syndactyly2TMEM94 CL E G H9772618316618316618316OMIM15328983618163
HP:0012725HP:00119393-4 finger cutaneous syndactyly2TMEM94 CL E G H9772618316618316618316OMIM15328983618163
HP:0012725HP:00057092-3 toe cutaneous syndactyly2TMEM94 CL E G H9772618316618316618316OMIM14628983618163
HP:0012725HP:00119393-4 finger cutaneous syndactyly2TMEM94 CL E G H9772618316618316618316OMIM14628983618163
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2TMEM94 CL E G H9772618316618316618316OMIM15328983618163
HP:0012725HP:00057682-4 toe cutaneous syndactyly2TMEM94 CL E G H9772618316618316618316OMIM15328983618163
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2TMEM94 CL E G H9772618316618316618316OMIM15328983618163
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52TMEM94 CL E G H9772618316618316618316OMIM15328983618163
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2TMEM94 CL E G H9772618316618316618316OMIM14628983618163
HP:0012725HP:00057682-4 toe cutaneous syndactyly2TMEM94 CL E G H9772618316618316618316OMIM14628983618163
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2TMEM94 CL E G H9772618316618316618316OMIM14628983618163
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52TMEM94 CL E G H9772618316618316618316OMIM14628983618163
HP:0012725HP:00057092-3 toe cutaneous syndactyly2TWIST1 CL E G H7291617746SWEENEY-COX SYNDROME617746C4540299OMIM116312428601622
HP:0012725HP:00119393-4 finger cutaneous syndactyly2TWIST1 CL E G H7291617746SWEENEY-COX SYNDROME617746C4540299OMIM116312428601622
HP:0012725HP:00057092-3 toe cutaneous syndactyly2TWIST1 CL E G H7291617746SWEENEY-COX SYNDROME617746C4540299OMIM114212428601622
HP:0012725HP:00119393-4 finger cutaneous syndactyly2TWIST1 CL E G H7291617746SWEENEY-COX SYNDROME617746C4540299OMIM114212428601622
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52TWIST1 CL E G H7291617746SWEENEY-COX SYNDROME617746C4540299OMIM116312428601622
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2TWIST1 CL E G H7291617746SWEENEY-COX SYNDROME617746C4540299OMIM116312428601622
HP:0012725HP:00057682-4 toe cutaneous syndactyly2TWIST1 CL E G H7291617746SWEENEY-COX SYNDROME617746C4540299OMIM116312428601622
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2TWIST1 CL E G H7291617746SWEENEY-COX SYNDROME617746C4540299OMIM116312428601622
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2TWIST1 CL E G H7291617746SWEENEY-COX SYNDROME617746C4540299OMIM114212428601622
HP:0012725HP:00057682-4 toe cutaneous syndactyly2TWIST1 CL E G H7291617746SWEENEY-COX SYNDROME617746C4540299OMIM114212428601622
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2TWIST1 CL E G H7291617746SWEENEY-COX SYNDROME617746C4540299OMIM114212428601622
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52TWIST1 CL E G H7291617746SWEENEY-COX SYNDROME617746C4540299OMIM114212428601622
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0012725HP:0012725Cutaneous syndactyly0CDH1 CL E G H999119580Ectropion inferior cleft lip and or palate119580C1861536OMIM030461748192090
HP:0012725HP:0012725Cutaneous syndactyly0CDH1 CL E G H999119580Ectropion inferior cleft lip and or palate119580C1861536OMIM028181748192090
HP:0012725HP:0012725Cutaneous syndactyly0TBC1D24 CL E G H5746579500ORPHA073829203613577
HP:0012725HP:0012725Cutaneous syndactyly0TBC1D24 CL E G H5746579500ORPHA066629203613577
HP:0012725HP:0010621Cutaneous syndactyly of toes1CDH1 CL E G H999119580Ectropion inferior cleft lip and or palate119580C1861536OMIM030461748192090
HP:0012725HP:0010554Cutaneous finger syndactyly1CDH1 CL E G H999119580Ectropion inferior cleft lip and or palate119580C1861536OMIM030461748192090
HP:0012725HP:0010621Cutaneous syndactyly of toes1CDH1 CL E G H999119580Ectropion inferior cleft lip and or palate119580C1861536OMIM028181748192090
HP:0012725HP:0010554Cutaneous finger syndactyly1CDH1 CL E G H999119580Ectropion inferior cleft lip and or palate119580C1861536OMIM028181748192090
HP:0012725HP:0010621Cutaneous syndactyly of toes1TBC1D24 CL E G H5746579500ORPHA073829203613577
HP:0012725HP:0010554Cutaneous finger syndactyly1TBC1D24 CL E G H5746579500ORPHA073829203613577
HP:0012725HP:0010621Cutaneous syndactyly of toes1TBC1D24 CL E G H5746579500ORPHA066629203613577
HP:0012725HP:0010554Cutaneous finger syndactyly1TBC1D24 CL E G H5746579500ORPHA066629203613577
HP:0012725HP:00119393-4 finger cutaneous syndactyly2CDH1 CL E G H999119580Ectropion inferior cleft lip and or palate119580C1861536OMIM030461748192090
HP:0012725HP:00057092-3 toe cutaneous syndactyly2CDH1 CL E G H999119580Ectropion inferior cleft lip and or palate119580C1861536OMIM030461748192090
HP:0012725HP:00119393-4 finger cutaneous syndactyly2CDH1 CL E G H999119580Ectropion inferior cleft lip and or palate119580C1861536OMIM028181748192090
HP:0012725HP:00057092-3 toe cutaneous syndactyly2CDH1 CL E G H999119580Ectropion inferior cleft lip and or palate119580C1861536OMIM028181748192090
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2CDH1 CL E G H999119580Ectropion inferior cleft lip and or palate119580C1861536OMIM030461748192090
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52CDH1 CL E G H999119580Ectropion inferior cleft lip and or palate119580C1861536OMIM030461748192090
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2CDH1 CL E G H999119580Ectropion inferior cleft lip and or palate119580C1861536OMIM030461748192090
HP:0012725HP:00057682-4 toe cutaneous syndactyly2CDH1 CL E G H999119580Ectropion inferior cleft lip and or palate119580C1861536OMIM030461748192090
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2CDH1 CL E G H999119580Ectropion inferior cleft lip and or palate119580C1861536OMIM028181748192090
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52CDH1 CL E G H999119580Ectropion inferior cleft lip and or palate119580C1861536OMIM028181748192090
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2CDH1 CL E G H999119580Ectropion inferior cleft lip and or palate119580C1861536OMIM028181748192090
HP:0012725HP:00057682-4 toe cutaneous syndactyly2CDH1 CL E G H999119580Ectropion inferior cleft lip and or palate119580C1861536OMIM028181748192090
HP:0012725HP:00057092-3 toe cutaneous syndactyly2TBC1D24 CL E G H5746579500ORPHA073829203613577
HP:0012725HP:00119393-4 finger cutaneous syndactyly2TBC1D24 CL E G H5746579500ORPHA073829203613577
HP:0012725HP:00057092-3 toe cutaneous syndactyly2TBC1D24 CL E G H5746579500ORPHA066629203613577
HP:0012725HP:00119393-4 finger cutaneous syndactyly2TBC1D24 CL E G H5746579500ORPHA066629203613577
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2TBC1D24 CL E G H5746579500ORPHA073829203613577
HP:0012725HP:00057682-4 toe cutaneous syndactyly2TBC1D24 CL E G H5746579500ORPHA073829203613577
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2TBC1D24 CL E G H5746579500ORPHA073829203613577
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52TBC1D24 CL E G H5746579500ORPHA073829203613577
HP:0012725HP:00057671-2 toe complete cutaneous syndactyly2TBC1D24 CL E G H5746579500ORPHA066629203613577
HP:0012725HP:00057682-4 toe cutaneous syndactyly2TBC1D24 CL E G H5746579500ORPHA066629203613577
HP:0012725HP:00060881-5 finger complete cutaneous syndactyly2TBC1D24 CL E G H5746579500ORPHA066629203613577
HP:0012725HP:0005650Cutaneous syndactyly between fingers 2 and 52TBC1D24 CL E G H5746579500ORPHA066629203613577


Genes (41) :ANKRD11 BHLHA9 CACNA1C CCBE1 CDH1 CKAP2L DCHS1 FAT4 FGF9 FGFR2 FRAS1 GJA1 GLI3 GRIP1 HOXD13 IRF6 KCTD1 KIAA1109 LEMD3 LMBR1 LRP4 MAP3K20 MCTP2 MEGF8 MEIS2 MYH8 NECTIN1 NECTIN4 NOG ORC1 PAX3 PIEZO2 RBM10 ROR2 SMARCAD1 SMO TBC1D24 TMEM94 TP63 TWIST1 WDR19

Diseases (43) :2332 607539 601005 119580 272440 617667 617822 616890 600987 311900 79500 618316 617746 235510 601390 615546 612961 101200 219000 186300 119500 1306 614305 614976 158300 225060 613573 611377 186500 224690 896 148820 114300 113000 129200 601707 614378 257850 672 181270 186200 1596 69085
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.