Human Phenotype Ontology

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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Abnormality of the peripheral nervous system (HP:0410008)

Parent Node:
Abnormality of the autonomic nervous system (HP:0002270)

..Starting node
..Abnormal autonomic nervous system physiology (HP:0012332)

Term ID:

12332

Name:

Abnormal autonomic nervous system physiology

Synonym:

Autonomic dysfunction; Autonomic dysregulation; Dysautonomia

Definition:

A functional abnormality of the autonomic nervous system.

Comments:

Reference:

HP:0012332

Genes and Diseases:

Child Nodes:

........

Orthostatic hypotension (HP:0001278)

................... HP:0004926 Orthostatic hypotension due to autonomic dysfunction
................... HP:0005307 Postural hypotension with compensatory tachycardia

........

Autonomic dysregulation (HP:0002271)

........

Horner syndrome (HP:0002277)

................... HP:0006837 Congenital Horner syndrome

........

Dysautonomia (HP:0002459)

................... HP:0005341 Autonomic bladder dysfunction
................... HP:0008652 Autonomic erectile dysfunction

........

Orthostatic tachycardia (HP:0012173)

........

Abnormal sudomotor regulation (HP:0012333)

Sister Nodes:

Abnormal autonomic nervous system morphology (HP:0012331)

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	DiseaseId	DiseaseName	DiseaseMIM	ConceptID	Source	Typical association	ClinVar variants	HGNC ID	GeneMIM
HPO disease - gene - phenotype typical associations:
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	ASCL1 CL E G H	429	99803	Haddad syndrome		C1859587	ORPHA	1	32	738	100790
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	BRAT1 CL E G H	221927	614498	Rigidity and multifocal seizure syndrome, lethal neonatal	614498	C3281029	OMIM	1	960	21701	614506
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	CCT5 CL E G H	22948	139578				ORPHA	1	314	1618	610150
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	ECE1 CL E G H	1889	613870	Hirschsprung disease, cardiac defects, and autonomic dysfunction	613870	C3151237	OMIM	1	49	3146	600423
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	FBXO7 CL E G H	25793	171695				ORPHA	1	191	13586	605648
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	FMR1 CL E G H	2332	93256				ORPHA	1	338	3775	309550
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	GABBR2 CL E G H	9568	617903	NEURODEVELOPMENTAL DISORDER WITH POOR LANGUAGE AND LOSS OF HAND SKILLS	617903	CN870852	OMIM	1	682	4507	607340
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	GLA CL E G H	2717	301500	Fabry disease	301500	C0002986	OMIM	1	1002	4296	300644
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	LIFR CL E G H	3977	601559	Stuve-Wiedemann syndrome	601559	C0796176	OMIM	1	721	6597	151443
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	PHOX2B CL E G H	8929	99803	Haddad syndrome		C1859587	ORPHA	1	840	9143	603851
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	PRNP CL E G H	5621	282166				ORPHA	1	164	9449	176640
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	PRNP CL E G H	5621	600072	Fatal familial insomnia	600072	C0206042	OMIM	1	164	9449	176640
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	RET CL E G H	5979	99803	Haddad syndrome		C1859587	ORPHA	1	2692	9967	164761
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	SCN11A CL E G H	11280	615552	Episodic pain syndrome, familial, 3	615552	C3809899	OMIM	1	1004	10583	604385
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	SCN11A CL E G H	11280	615548	Neuropathy, hereditary sensory and autonomic, type VII	615548	C3809882	OMIM	1	1004	10583	604385
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	SCN3A CL E G H	6328	617935	EPILEPSY, FAMILIAL FOCAL, WITH VARIABLE FOCI 4	617935	CN244552	OMIM	1	1096	10590	182391
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	SCN9A CL E G H	6335	243000	Indifference to pain, congenital, autosomal recessive	243000	C1855739	OMIM	1	1907	10597	603415
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	SLC18A2 CL E G H	6571	618049	PARKINSONISM-DYSTONIA, INFANTILE, 2	618049	CN248785	OMIM	1	124	10935	193001
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	SNCA CL E G H	6622	171695				ORPHA	1	177	11138	163890
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	SOX10 CL E G H	6663	609136	Peripheral demyelinating neuropathy, central dysmyelination, Waardenburg syndrome, and Hirschsprung disease	609136	C1836727	OMIM	1	302	11190	602229
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	TCF4 CL E G H	6925	610954	Pitt-Hopkins syndrome	610954	C1970431	OMIM	1	913	11634	602272
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	TSPYL1 CL E G H	7259	168593				ORPHA	1	48	12382	604714
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	TTR CL E G H	7276	85447				ORPHA	1	341	12405	176300
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	TXN2 CL E G H	25828	478029				ORPHA	1	50	17772	609063
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	VPS11 CL E G H	55823	466934				ORPHA	1	139	14583	608549
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	VPS11 CL E G H	55823	616683	Leukodystrophy, hypomyelinating, 12	616683	C4225247	OMIM	1	139	14583	608549
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	WDR45 CL E G H	11152	329284				ORPHA	1	504	28912	300526
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	WDR45 CL E G H	11152	300894	Neurodegeneration with brain iron accumulation 5	300894	C3550973	OMIM	1	504	28912	300526
HP:0012332	HP:0012173	Orthostatic tachycardia	1	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0012332	HP:0001278	Orthostatic hypotension	1	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0012332	HP:0002277	Horner syndrome	1	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0012332	HP:0012173	Orthostatic tachycardia	1	ASCL1 CL E G H	429	99803	Haddad syndrome		C1859587	ORPHA	1	32	738	100790
HP:0012332	HP:0001278	Orthostatic hypotension	1	ASCL1 CL E G H	429	99803	Haddad syndrome		C1859587	ORPHA	1	32	738	100790
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	ASCL1 CL E G H	429	99803	Haddad syndrome		C1859587	ORPHA	1	32	738	100790
HP:0012332	HP:0002277	Horner syndrome	1	ASCL1 CL E G H	429	99803	Haddad syndrome		C1859587	ORPHA	1	32	738	100790
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	ASCL1 CL E G H	429	99803	Haddad syndrome		C1859587	ORPHA	1	32	738	100790
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	ASCL1 CL E G H	429	99803	Haddad syndrome		C1859587	ORPHA	1	32	738	100790
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	BRAT1 CL E G H	221927	614498	Rigidity and multifocal seizure syndrome, lethal neonatal	614498	C3281029	OMIM	1	960	21701	614506
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	BRAT1 CL E G H	221927	614498	Rigidity and multifocal seizure syndrome, lethal neonatal	614498	C3281029	OMIM	1	960	21701	614506
HP:0012332	HP:0012173	Orthostatic tachycardia	1	BRAT1 CL E G H	221927	614498	Rigidity and multifocal seizure syndrome, lethal neonatal	614498	C3281029	OMIM	1	960	21701	614506
HP:0012332	HP:0001278	Orthostatic hypotension	1	BRAT1 CL E G H	221927	614498	Rigidity and multifocal seizure syndrome, lethal neonatal	614498	C3281029	OMIM	1	960	21701	614506
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	BRAT1 CL E G H	221927	614498	Rigidity and multifocal seizure syndrome, lethal neonatal	614498	C3281029	OMIM	1	960	21701	614506
HP:0012332	HP:0002277	Horner syndrome	1	BRAT1 CL E G H	221927	614498	Rigidity and multifocal seizure syndrome, lethal neonatal	614498	C3281029	OMIM	1	960	21701	614506
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	CCT5 CL E G H	22948	139578				ORPHA	1	314	1618	610150
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	CCT5 CL E G H	22948	139578				ORPHA	1	314	1618	610150
HP:0012332	HP:0001278	Orthostatic hypotension	1	CCT5 CL E G H	22948	139578				ORPHA	1	314	1618	610150
HP:0012332	HP:0012173	Orthostatic tachycardia	1	CCT5 CL E G H	22948	139578				ORPHA	1	314	1618	610150
HP:0012332	HP:0002277	Horner syndrome	1	CCT5 CL E G H	22948	139578				ORPHA	1	314	1618	610150
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	CCT5 CL E G H	22948	139578				ORPHA	1	314	1618	610150
HP:0012332	HP:0001278	Orthostatic hypotension	1	ECE1 CL E G H	1889	613870	Hirschsprung disease, cardiac defects, and autonomic dysfunction	613870	C3151237	OMIM	1	49	3146	600423
HP:0012332	HP:0012173	Orthostatic tachycardia	1	ECE1 CL E G H	1889	613870	Hirschsprung disease, cardiac defects, and autonomic dysfunction	613870	C3151237	OMIM	1	49	3146	600423
HP:0012332	HP:0002277	Horner syndrome	1	ECE1 CL E G H	1889	613870	Hirschsprung disease, cardiac defects, and autonomic dysfunction	613870	C3151237	OMIM	1	49	3146	600423
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	ECE1 CL E G H	1889	613870	Hirschsprung disease, cardiac defects, and autonomic dysfunction	613870	C3151237	OMIM	1	49	3146	600423
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	ECE1 CL E G H	1889	613870	Hirschsprung disease, cardiac defects, and autonomic dysfunction	613870	C3151237	OMIM	1	49	3146	600423
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	ECE1 CL E G H	1889	613870	Hirschsprung disease, cardiac defects, and autonomic dysfunction	613870	C3151237	OMIM	1	49	3146	600423
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	FBXO7 CL E G H	25793	171695				ORPHA	1	191	13586	605648
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	FBXO7 CL E G H	25793	171695				ORPHA	1	191	13586	605648
HP:0012332	HP:0001278	Orthostatic hypotension	1	FBXO7 CL E G H	25793	171695				ORPHA	1	191	13586	605648
HP:0012332	HP:0012173	Orthostatic tachycardia	1	FBXO7 CL E G H	25793	171695				ORPHA	1	191	13586	605648
HP:0012332	HP:0002277	Horner syndrome	1	FBXO7 CL E G H	25793	171695				ORPHA	1	191	13586	605648
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	FBXO7 CL E G H	25793	171695				ORPHA	1	191	13586	605648
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	FMR1 CL E G H	2332	93256				ORPHA	1	338	3775	309550
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	FMR1 CL E G H	2332	93256				ORPHA	1	338	3775	309550
HP:0012332	HP:0001278	Orthostatic hypotension	1	FMR1 CL E G H	2332	93256				ORPHA	1	338	3775	309550
HP:0012332	HP:0012173	Orthostatic tachycardia	1	FMR1 CL E G H	2332	93256				ORPHA	1	338	3775	309550
HP:0012332	HP:0002277	Horner syndrome	1	FMR1 CL E G H	2332	93256				ORPHA	1	338	3775	309550
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	FMR1 CL E G H	2332	93256				ORPHA	1	338	3775	309550
HP:0012332	HP:0001278	Orthostatic hypotension	1	GABBR2 CL E G H	9568	617903	NEURODEVELOPMENTAL DISORDER WITH POOR LANGUAGE AND LOSS OF HAND SKILLS	617903	CN870852	OMIM	1	682	4507	607340
HP:0012332	HP:0012173	Orthostatic tachycardia	1	GABBR2 CL E G H	9568	617903	NEURODEVELOPMENTAL DISORDER WITH POOR LANGUAGE AND LOSS OF HAND SKILLS	617903	CN870852	OMIM	1	682	4507	607340
HP:0012332	HP:0002277	Horner syndrome	1	GABBR2 CL E G H	9568	617903	NEURODEVELOPMENTAL DISORDER WITH POOR LANGUAGE AND LOSS OF HAND SKILLS	617903	CN870852	OMIM	1	682	4507	607340
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	GABBR2 CL E G H	9568	617903	NEURODEVELOPMENTAL DISORDER WITH POOR LANGUAGE AND LOSS OF HAND SKILLS	617903	CN870852	OMIM	1	682	4507	607340
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	GABBR2 CL E G H	9568	617903	NEURODEVELOPMENTAL DISORDER WITH POOR LANGUAGE AND LOSS OF HAND SKILLS	617903	CN870852	OMIM	1	682	4507	607340
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	GABBR2 CL E G H	9568	617903	NEURODEVELOPMENTAL DISORDER WITH POOR LANGUAGE AND LOSS OF HAND SKILLS	617903	CN870852	OMIM	1	682	4507	607340
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	GLA CL E G H	2717	301500	Fabry disease	301500	C0002986	OMIM	1	1002	4296	300644
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	GLA CL E G H	2717	301500	Fabry disease	301500	C0002986	OMIM	1	1002	4296	300644
HP:0012332	HP:0001278	Orthostatic hypotension	1	GLA CL E G H	2717	301500	Fabry disease	301500	C0002986	OMIM	1	1002	4296	300644
HP:0012332	HP:0012173	Orthostatic tachycardia	1	GLA CL E G H	2717	301500	Fabry disease	301500	C0002986	OMIM	1	1002	4296	300644
HP:0012332	HP:0002277	Horner syndrome	1	GLA CL E G H	2717	301500	Fabry disease	301500	C0002986	OMIM	1	1002	4296	300644
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	GLA CL E G H	2717	301500	Fabry disease	301500	C0002986	OMIM	1	1002	4296	300644
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0012332	HP:0001278	Orthostatic hypotension	1	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0012332	HP:0012173	Orthostatic tachycardia	1	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0012332	HP:0002277	Horner syndrome	1	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	LIFR CL E G H	3977	601559	Stuve-Wiedemann syndrome	601559	C0796176	OMIM	1	721	6597	151443
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	LIFR CL E G H	3977	601559	Stuve-Wiedemann syndrome	601559	C0796176	OMIM	1	721	6597	151443
HP:0012332	HP:0012173	Orthostatic tachycardia	1	LIFR CL E G H	3977	601559	Stuve-Wiedemann syndrome	601559	C0796176	OMIM	1	721	6597	151443
HP:0012332	HP:0001278	Orthostatic hypotension	1	LIFR CL E G H	3977	601559	Stuve-Wiedemann syndrome	601559	C0796176	OMIM	1	721	6597	151443
HP:0012332	HP:0002277	Horner syndrome	1	LIFR CL E G H	3977	601559	Stuve-Wiedemann syndrome	601559	C0796176	OMIM	1	721	6597	151443
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	LIFR CL E G H	3977	601559	Stuve-Wiedemann syndrome	601559	C0796176	OMIM	1	721	6597	151443
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	PHOX2B CL E G H	8929	99803	Haddad syndrome		C1859587	ORPHA	1	840	9143	603851
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	PHOX2B CL E G H	8929	99803	Haddad syndrome		C1859587	ORPHA	1	840	9143	603851
HP:0012332	HP:0001278	Orthostatic hypotension	1	PHOX2B CL E G H	8929	99803	Haddad syndrome		C1859587	ORPHA	1	840	9143	603851
HP:0012332	HP:0012173	Orthostatic tachycardia	1	PHOX2B CL E G H	8929	99803	Haddad syndrome		C1859587	ORPHA	1	840	9143	603851
HP:0012332	HP:0002277	Horner syndrome	1	PHOX2B CL E G H	8929	99803	Haddad syndrome		C1859587	ORPHA	1	840	9143	603851
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	PHOX2B CL E G H	8929	99803	Haddad syndrome		C1859587	ORPHA	1	840	9143	603851
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	PRNP CL E G H	5621	282166				ORPHA	1	164	9449	176640
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	PRNP CL E G H	5621	282166				ORPHA	1	164	9449	176640
HP:0012332	HP:0012173	Orthostatic tachycardia	1	PRNP CL E G H	5621	282166				ORPHA	1	164	9449	176640
HP:0012332	HP:0001278	Orthostatic hypotension	1	PRNP CL E G H	5621	282166				ORPHA	1	164	9449	176640
HP:0012332	HP:0002277	Horner syndrome	1	PRNP CL E G H	5621	282166				ORPHA	1	164	9449	176640
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	PRNP CL E G H	5621	282166				ORPHA	1	164	9449	176640
HP:0012332	HP:0001278	Orthostatic hypotension	1	PRNP CL E G H	5621	600072	Fatal familial insomnia	600072	C0206042	OMIM	1	164	9449	176640
HP:0012332	HP:0012173	Orthostatic tachycardia	1	PRNP CL E G H	5621	600072	Fatal familial insomnia	600072	C0206042	OMIM	1	164	9449	176640
HP:0012332	HP:0002277	Horner syndrome	1	PRNP CL E G H	5621	600072	Fatal familial insomnia	600072	C0206042	OMIM	1	164	9449	176640
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	PRNP CL E G H	5621	600072	Fatal familial insomnia	600072	C0206042	OMIM	1	164	9449	176640
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	PRNP CL E G H	5621	600072	Fatal familial insomnia	600072	C0206042	OMIM	1	164	9449	176640
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	PRNP CL E G H	5621	600072	Fatal familial insomnia	600072	C0206042	OMIM	1	164	9449	176640
HP:0012332	HP:0012173	Orthostatic tachycardia	1	RET CL E G H	5979	99803	Haddad syndrome		C1859587	ORPHA	1	2692	9967	164761
HP:0012332	HP:0001278	Orthostatic hypotension	1	RET CL E G H	5979	99803	Haddad syndrome		C1859587	ORPHA	1	2692	9967	164761
HP:0012332	HP:0002277	Horner syndrome	1	RET CL E G H	5979	99803	Haddad syndrome		C1859587	ORPHA	1	2692	9967	164761
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	RET CL E G H	5979	99803	Haddad syndrome		C1859587	ORPHA	1	2692	9967	164761
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	RET CL E G H	5979	99803	Haddad syndrome		C1859587	ORPHA	1	2692	9967	164761
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	RET CL E G H	5979	99803	Haddad syndrome		C1859587	ORPHA	1	2692	9967	164761
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	SCN11A CL E G H	11280	615552	Episodic pain syndrome, familial, 3	615552	C3809899	OMIM	1	1004	10583	604385
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	SCN11A CL E G H	11280	615552	Episodic pain syndrome, familial, 3	615552	C3809899	OMIM	1	1004	10583	604385
HP:0012332	HP:0012173	Orthostatic tachycardia	1	SCN11A CL E G H	11280	615552	Episodic pain syndrome, familial, 3	615552	C3809899	OMIM	1	1004	10583	604385
HP:0012332	HP:0001278	Orthostatic hypotension	1	SCN11A CL E G H	11280	615552	Episodic pain syndrome, familial, 3	615552	C3809899	OMIM	1	1004	10583	604385
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	SCN11A CL E G H	11280	615552	Episodic pain syndrome, familial, 3	615552	C3809899	OMIM	1	1004	10583	604385
HP:0012332	HP:0002277	Horner syndrome	1	SCN11A CL E G H	11280	615552	Episodic pain syndrome, familial, 3	615552	C3809899	OMIM	1	1004	10583	604385
HP:0012332	HP:0001278	Orthostatic hypotension	1	SCN11A CL E G H	11280	615548	Neuropathy, hereditary sensory and autonomic, type VII	615548	C3809882	OMIM	1	1004	10583	604385
HP:0012332	HP:0012173	Orthostatic tachycardia	1	SCN11A CL E G H	11280	615548	Neuropathy, hereditary sensory and autonomic, type VII	615548	C3809882	OMIM	1	1004	10583	604385
HP:0012332	HP:0002277	Horner syndrome	1	SCN11A CL E G H	11280	615548	Neuropathy, hereditary sensory and autonomic, type VII	615548	C3809882	OMIM	1	1004	10583	604385
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	SCN11A CL E G H	11280	615548	Neuropathy, hereditary sensory and autonomic, type VII	615548	C3809882	OMIM	1	1004	10583	604385
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	SCN11A CL E G H	11280	615548	Neuropathy, hereditary sensory and autonomic, type VII	615548	C3809882	OMIM	1	1004	10583	604385
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	SCN11A CL E G H	11280	615548	Neuropathy, hereditary sensory and autonomic, type VII	615548	C3809882	OMIM	1	1004	10583	604385
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	SCN3A CL E G H	6328	617935	EPILEPSY, FAMILIAL FOCAL, WITH VARIABLE FOCI 4	617935	CN244552	OMIM	1	1096	10590	182391
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	SCN3A CL E G H	6328	617935	EPILEPSY, FAMILIAL FOCAL, WITH VARIABLE FOCI 4	617935	CN244552	OMIM	1	1096	10590	182391
HP:0012332	HP:0012173	Orthostatic tachycardia	1	SCN3A CL E G H	6328	617935	EPILEPSY, FAMILIAL FOCAL, WITH VARIABLE FOCI 4	617935	CN244552	OMIM	1	1096	10590	182391
HP:0012332	HP:0001278	Orthostatic hypotension	1	SCN3A CL E G H	6328	617935	EPILEPSY, FAMILIAL FOCAL, WITH VARIABLE FOCI 4	617935	CN244552	OMIM	1	1096	10590	182391
HP:0012332	HP:0002277	Horner syndrome	1	SCN3A CL E G H	6328	617935	EPILEPSY, FAMILIAL FOCAL, WITH VARIABLE FOCI 4	617935	CN244552	OMIM	1	1096	10590	182391
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	SCN3A CL E G H	6328	617935	EPILEPSY, FAMILIAL FOCAL, WITH VARIABLE FOCI 4	617935	CN244552	OMIM	1	1096	10590	182391
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	SCN9A CL E G H	6335	243000	Indifference to pain, congenital, autosomal recessive	243000	C1855739	OMIM	1	1907	10597	603415
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	SCN9A CL E G H	6335	243000	Indifference to pain, congenital, autosomal recessive	243000	C1855739	OMIM	1	1907	10597	603415
HP:0012332	HP:0001278	Orthostatic hypotension	1	SCN9A CL E G H	6335	243000	Indifference to pain, congenital, autosomal recessive	243000	C1855739	OMIM	1	1907	10597	603415
HP:0012332	HP:0012173	Orthostatic tachycardia	1	SCN9A CL E G H	6335	243000	Indifference to pain, congenital, autosomal recessive	243000	C1855739	OMIM	1	1907	10597	603415
HP:0012332	HP:0002277	Horner syndrome	1	SCN9A CL E G H	6335	243000	Indifference to pain, congenital, autosomal recessive	243000	C1855739	OMIM	1	1907	10597	603415
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	SCN9A CL E G H	6335	243000	Indifference to pain, congenital, autosomal recessive	243000	C1855739	OMIM	1	1907	10597	603415
HP:0012332	HP:0001278	Orthostatic hypotension	1	SLC18A2 CL E G H	6571	618049	PARKINSONISM-DYSTONIA, INFANTILE, 2	618049	CN248785	OMIM	1	124	10935	193001
HP:0012332	HP:0012173	Orthostatic tachycardia	1	SLC18A2 CL E G H	6571	618049	PARKINSONISM-DYSTONIA, INFANTILE, 2	618049	CN248785	OMIM	1	124	10935	193001
HP:0012332	HP:0002277	Horner syndrome	1	SLC18A2 CL E G H	6571	618049	PARKINSONISM-DYSTONIA, INFANTILE, 2	618049	CN248785	OMIM	1	124	10935	193001
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	SLC18A2 CL E G H	6571	618049	PARKINSONISM-DYSTONIA, INFANTILE, 2	618049	CN248785	OMIM	1	124	10935	193001
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	SLC18A2 CL E G H	6571	618049	PARKINSONISM-DYSTONIA, INFANTILE, 2	618049	CN248785	OMIM	1	124	10935	193001
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	SLC18A2 CL E G H	6571	618049	PARKINSONISM-DYSTONIA, INFANTILE, 2	618049	CN248785	OMIM	1	124	10935	193001
HP:0012332	HP:0001278	Orthostatic hypotension	1	SNCA CL E G H	6622	171695				ORPHA	1	177	11138	163890
HP:0012332	HP:0012173	Orthostatic tachycardia	1	SNCA CL E G H	6622	171695				ORPHA	1	177	11138	163890
HP:0012332	HP:0002277	Horner syndrome	1	SNCA CL E G H	6622	171695				ORPHA	1	177	11138	163890
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	SNCA CL E G H	6622	171695				ORPHA	1	177	11138	163890
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	SNCA CL E G H	6622	171695				ORPHA	1	177	11138	163890
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	SNCA CL E G H	6622	171695				ORPHA	1	177	11138	163890
HP:0012332	HP:0001278	Orthostatic hypotension	1	SOX10 CL E G H	6663	609136	Peripheral demyelinating neuropathy, central dysmyelination, Waardenburg syndrome, and Hirschsprung disease	609136	C1836727	OMIM	1	302	11190	602229
HP:0012332	HP:0012173	Orthostatic tachycardia	1	SOX10 CL E G H	6663	609136	Peripheral demyelinating neuropathy, central dysmyelination, Waardenburg syndrome, and Hirschsprung disease	609136	C1836727	OMIM	1	302	11190	602229
HP:0012332	HP:0002277	Horner syndrome	1	SOX10 CL E G H	6663	609136	Peripheral demyelinating neuropathy, central dysmyelination, Waardenburg syndrome, and Hirschsprung disease	609136	C1836727	OMIM	1	302	11190	602229
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	SOX10 CL E G H	6663	609136	Peripheral demyelinating neuropathy, central dysmyelination, Waardenburg syndrome, and Hirschsprung disease	609136	C1836727	OMIM	1	302	11190	602229
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	SOX10 CL E G H	6663	609136	Peripheral demyelinating neuropathy, central dysmyelination, Waardenburg syndrome, and Hirschsprung disease	609136	C1836727	OMIM	1	302	11190	602229
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	SOX10 CL E G H	6663	609136	Peripheral demyelinating neuropathy, central dysmyelination, Waardenburg syndrome, and Hirschsprung disease	609136	C1836727	OMIM	1	302	11190	602229
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	TCF4 CL E G H	6925	610954	Pitt-Hopkins syndrome	610954	C1970431	OMIM	1	913	11634	602272
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	TCF4 CL E G H	6925	610954	Pitt-Hopkins syndrome	610954	C1970431	OMIM	1	913	11634	602272
HP:0012332	HP:0012173	Orthostatic tachycardia	1	TCF4 CL E G H	6925	610954	Pitt-Hopkins syndrome	610954	C1970431	OMIM	1	913	11634	602272
HP:0012332	HP:0001278	Orthostatic hypotension	1	TCF4 CL E G H	6925	610954	Pitt-Hopkins syndrome	610954	C1970431	OMIM	1	913	11634	602272
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	TCF4 CL E G H	6925	610954	Pitt-Hopkins syndrome	610954	C1970431	OMIM	1	913	11634	602272
HP:0012332	HP:0002277	Horner syndrome	1	TCF4 CL E G H	6925	610954	Pitt-Hopkins syndrome	610954	C1970431	OMIM	1	913	11634	602272
HP:0012332	HP:0012173	Orthostatic tachycardia	1	TSPYL1 CL E G H	7259	168593				ORPHA	1	48	12382	604714
HP:0012332	HP:0001278	Orthostatic hypotension	1	TSPYL1 CL E G H	7259	168593				ORPHA	1	48	12382	604714
HP:0012332	HP:0002277	Horner syndrome	1	TSPYL1 CL E G H	7259	168593				ORPHA	1	48	12382	604714
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	TSPYL1 CL E G H	7259	168593				ORPHA	1	48	12382	604714
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	TSPYL1 CL E G H	7259	168593				ORPHA	1	48	12382	604714
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	TSPYL1 CL E G H	7259	168593				ORPHA	1	48	12382	604714
HP:0012332	HP:0012173	Orthostatic tachycardia	1	TTR CL E G H	7276	85447				ORPHA	1	341	12405	176300
HP:0012332	HP:0001278	Orthostatic hypotension	1	TTR CL E G H	7276	85447				ORPHA	1	341	12405	176300
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	TTR CL E G H	7276	85447				ORPHA	1	341	12405	176300
HP:0012332	HP:0002277	Horner syndrome	1	TTR CL E G H	7276	85447				ORPHA	1	341	12405	176300
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	TTR CL E G H	7276	85447				ORPHA	1	341	12405	176300
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	TTR CL E G H	7276	85447				ORPHA	1	341	12405	176300
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	TXN2 CL E G H	25828	478029				ORPHA	1	50	17772	609063
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	TXN2 CL E G H	25828	478029				ORPHA	1	50	17772	609063
HP:0012332	HP:0012173	Orthostatic tachycardia	1	TXN2 CL E G H	25828	478029				ORPHA	1	50	17772	609063
HP:0012332	HP:0001278	Orthostatic hypotension	1	TXN2 CL E G H	25828	478029				ORPHA	1	50	17772	609063
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	TXN2 CL E G H	25828	478029				ORPHA	1	50	17772	609063
HP:0012332	HP:0002277	Horner syndrome	1	TXN2 CL E G H	25828	478029				ORPHA	1	50	17772	609063
HP:0012332	HP:0001278	Orthostatic hypotension	1	VPS11 CL E G H	55823	466934				ORPHA	1	139	14583	608549
HP:0012332	HP:0012173	Orthostatic tachycardia	1	VPS11 CL E G H	55823	466934				ORPHA	1	139	14583	608549
HP:0012332	HP:0002277	Horner syndrome	1	VPS11 CL E G H	55823	466934				ORPHA	1	139	14583	608549
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	VPS11 CL E G H	55823	466934				ORPHA	1	139	14583	608549
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	VPS11 CL E G H	55823	466934				ORPHA	1	139	14583	608549
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	VPS11 CL E G H	55823	466934				ORPHA	1	139	14583	608549
HP:0012332	HP:0001278	Orthostatic hypotension	1	VPS11 CL E G H	55823	616683	Leukodystrophy, hypomyelinating, 12	616683	C4225247	OMIM	1	139	14583	608549
HP:0012332	HP:0012173	Orthostatic tachycardia	1	VPS11 CL E G H	55823	616683	Leukodystrophy, hypomyelinating, 12	616683	C4225247	OMIM	1	139	14583	608549
HP:0012332	HP:0002277	Horner syndrome	1	VPS11 CL E G H	55823	616683	Leukodystrophy, hypomyelinating, 12	616683	C4225247	OMIM	1	139	14583	608549
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	VPS11 CL E G H	55823	616683	Leukodystrophy, hypomyelinating, 12	616683	C4225247	OMIM	1	139	14583	608549
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	VPS11 CL E G H	55823	616683	Leukodystrophy, hypomyelinating, 12	616683	C4225247	OMIM	1	139	14583	608549
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	VPS11 CL E G H	55823	616683	Leukodystrophy, hypomyelinating, 12	616683	C4225247	OMIM	1	139	14583	608549
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	WDR45 CL E G H	11152	329284				ORPHA	1	504	28912	300526
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	WDR45 CL E G H	11152	329284				ORPHA	1	504	28912	300526
HP:0012332	HP:0012173	Orthostatic tachycardia	1	WDR45 CL E G H	11152	329284				ORPHA	1	504	28912	300526
HP:0012332	HP:0001278	Orthostatic hypotension	1	WDR45 CL E G H	11152	329284				ORPHA	1	504	28912	300526
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	WDR45 CL E G H	11152	329284				ORPHA	1	504	28912	300526
HP:0012332	HP:0002277	Horner syndrome	1	WDR45 CL E G H	11152	329284				ORPHA	1	504	28912	300526
HP:0012332	HP:0012173	Orthostatic tachycardia	1	WDR45 CL E G H	11152	300894	Neurodegeneration with brain iron accumulation 5	300894	C3550973	OMIM	1	504	28912	300526
HP:0012332	HP:0001278	Orthostatic hypotension	1	WDR45 CL E G H	11152	300894	Neurodegeneration with brain iron accumulation 5	300894	C3550973	OMIM	1	504	28912	300526
HP:0012332	HP:0002277	Horner syndrome	1	WDR45 CL E G H	11152	300894	Neurodegeneration with brain iron accumulation 5	300894	C3550973	OMIM	1	504	28912	300526
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	WDR45 CL E G H	11152	300894	Neurodegeneration with brain iron accumulation 5	300894	C3550973	OMIM	1	504	28912	300526
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	WDR45 CL E G H	11152	300894	Neurodegeneration with brain iron accumulation 5	300894	C3550973	OMIM	1	504	28912	300526
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	WDR45 CL E G H	11152	300894	Neurodegeneration with brain iron accumulation 5	300894	C3550973	OMIM	1	504	28912	300526
HP:0012332	HP:0006837	Congenital Horner syndrome	2	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0012332	HP:0006837	Congenital Horner syndrome	2	ASCL1 CL E G H	429	99803	Haddad syndrome		C1859587	ORPHA	1	32	738	100790
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	ASCL1 CL E G H	429	99803	Haddad syndrome		C1859587	ORPHA	1	32	738	100790
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	ASCL1 CL E G H	429	99803	Haddad syndrome		C1859587	ORPHA	1	32	738	100790
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	BRAT1 CL E G H	221927	614498	Rigidity and multifocal seizure syndrome, lethal neonatal	614498	C3281029	OMIM	1	960	21701	614506
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	BRAT1 CL E G H	221927	614498	Rigidity and multifocal seizure syndrome, lethal neonatal	614498	C3281029	OMIM	1	960	21701	614506
HP:0012332	HP:0006837	Congenital Horner syndrome	2	BRAT1 CL E G H	221927	614498	Rigidity and multifocal seizure syndrome, lethal neonatal	614498	C3281029	OMIM	1	960	21701	614506
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	CCT5 CL E G H	22948	139578				ORPHA	1	314	1618	610150
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	CCT5 CL E G H	22948	139578				ORPHA	1	314	1618	610150
HP:0012332	HP:0006837	Congenital Horner syndrome	2	CCT5 CL E G H	22948	139578				ORPHA	1	314	1618	610150
HP:0012332	HP:0006837	Congenital Horner syndrome	2	ECE1 CL E G H	1889	613870	Hirschsprung disease, cardiac defects, and autonomic dysfunction	613870	C3151237	OMIM	1	49	3146	600423
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	ECE1 CL E G H	1889	613870	Hirschsprung disease, cardiac defects, and autonomic dysfunction	613870	C3151237	OMIM	1	49	3146	600423
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	ECE1 CL E G H	1889	613870	Hirschsprung disease, cardiac defects, and autonomic dysfunction	613870	C3151237	OMIM	1	49	3146	600423
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	FBXO7 CL E G H	25793	171695				ORPHA	1	191	13586	605648
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	FBXO7 CL E G H	25793	171695				ORPHA	1	191	13586	605648
HP:0012332	HP:0006837	Congenital Horner syndrome	2	FBXO7 CL E G H	25793	171695				ORPHA	1	191	13586	605648
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	FMR1 CL E G H	2332	93256				ORPHA	1	338	3775	309550
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	FMR1 CL E G H	2332	93256				ORPHA	1	338	3775	309550
HP:0012332	HP:0006837	Congenital Horner syndrome	2	FMR1 CL E G H	2332	93256				ORPHA	1	338	3775	309550
HP:0012332	HP:0006837	Congenital Horner syndrome	2	GABBR2 CL E G H	9568	617903	NEURODEVELOPMENTAL DISORDER WITH POOR LANGUAGE AND LOSS OF HAND SKILLS	617903	CN870852	OMIM	1	682	4507	607340
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	GABBR2 CL E G H	9568	617903	NEURODEVELOPMENTAL DISORDER WITH POOR LANGUAGE AND LOSS OF HAND SKILLS	617903	CN870852	OMIM	1	682	4507	607340
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	GABBR2 CL E G H	9568	617903	NEURODEVELOPMENTAL DISORDER WITH POOR LANGUAGE AND LOSS OF HAND SKILLS	617903	CN870852	OMIM	1	682	4507	607340
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	GLA CL E G H	2717	301500	Fabry disease	301500	C0002986	OMIM	1	1002	4296	300644
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	GLA CL E G H	2717	301500	Fabry disease	301500	C0002986	OMIM	1	1002	4296	300644
HP:0012332	HP:0006837	Congenital Horner syndrome	2	GLA CL E G H	2717	301500	Fabry disease	301500	C0002986	OMIM	1	1002	4296	300644
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0012332	HP:0006837	Congenital Horner syndrome	2	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	LIFR CL E G H	3977	601559	Stuve-Wiedemann syndrome	601559	C0796176	OMIM	1	721	6597	151443
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	LIFR CL E G H	3977	601559	Stuve-Wiedemann syndrome	601559	C0796176	OMIM	1	721	6597	151443
HP:0012332	HP:0006837	Congenital Horner syndrome	2	LIFR CL E G H	3977	601559	Stuve-Wiedemann syndrome	601559	C0796176	OMIM	1	721	6597	151443
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	PHOX2B CL E G H	8929	99803	Haddad syndrome		C1859587	ORPHA	1	840	9143	603851
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	PHOX2B CL E G H	8929	99803	Haddad syndrome		C1859587	ORPHA	1	840	9143	603851
HP:0012332	HP:0006837	Congenital Horner syndrome	2	PHOX2B CL E G H	8929	99803	Haddad syndrome		C1859587	ORPHA	1	840	9143	603851
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	PRNP CL E G H	5621	282166				ORPHA	1	164	9449	176640
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	PRNP CL E G H	5621	282166				ORPHA	1	164	9449	176640
HP:0012332	HP:0006837	Congenital Horner syndrome	2	PRNP CL E G H	5621	282166				ORPHA	1	164	9449	176640
HP:0012332	HP:0006837	Congenital Horner syndrome	2	PRNP CL E G H	5621	600072	Fatal familial insomnia	600072	C0206042	OMIM	1	164	9449	176640
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	PRNP CL E G H	5621	600072	Fatal familial insomnia	600072	C0206042	OMIM	1	164	9449	176640
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	PRNP CL E G H	5621	600072	Fatal familial insomnia	600072	C0206042	OMIM	1	164	9449	176640
HP:0012332	HP:0006837	Congenital Horner syndrome	2	RET CL E G H	5979	99803	Haddad syndrome		C1859587	ORPHA	1	2692	9967	164761
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	RET CL E G H	5979	99803	Haddad syndrome		C1859587	ORPHA	1	2692	9967	164761
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	RET CL E G H	5979	99803	Haddad syndrome		C1859587	ORPHA	1	2692	9967	164761
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	SCN11A CL E G H	11280	615552	Episodic pain syndrome, familial, 3	615552	C3809899	OMIM	1	1004	10583	604385
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	SCN11A CL E G H	11280	615552	Episodic pain syndrome, familial, 3	615552	C3809899	OMIM	1	1004	10583	604385
HP:0012332	HP:0006837	Congenital Horner syndrome	2	SCN11A CL E G H	11280	615552	Episodic pain syndrome, familial, 3	615552	C3809899	OMIM	1	1004	10583	604385
HP:0012332	HP:0006837	Congenital Horner syndrome	2	SCN11A CL E G H	11280	615548	Neuropathy, hereditary sensory and autonomic, type VII	615548	C3809882	OMIM	1	1004	10583	604385
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	SCN11A CL E G H	11280	615548	Neuropathy, hereditary sensory and autonomic, type VII	615548	C3809882	OMIM	1	1004	10583	604385
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	SCN11A CL E G H	11280	615548	Neuropathy, hereditary sensory and autonomic, type VII	615548	C3809882	OMIM	1	1004	10583	604385
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	SCN3A CL E G H	6328	617935	EPILEPSY, FAMILIAL FOCAL, WITH VARIABLE FOCI 4	617935	CN244552	OMIM	1	1096	10590	182391
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	SCN3A CL E G H	6328	617935	EPILEPSY, FAMILIAL FOCAL, WITH VARIABLE FOCI 4	617935	CN244552	OMIM	1	1096	10590	182391
HP:0012332	HP:0006837	Congenital Horner syndrome	2	SCN3A CL E G H	6328	617935	EPILEPSY, FAMILIAL FOCAL, WITH VARIABLE FOCI 4	617935	CN244552	OMIM	1	1096	10590	182391
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	SCN9A CL E G H	6335	243000	Indifference to pain, congenital, autosomal recessive	243000	C1855739	OMIM	1	1907	10597	603415
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	SCN9A CL E G H	6335	243000	Indifference to pain, congenital, autosomal recessive	243000	C1855739	OMIM	1	1907	10597	603415
HP:0012332	HP:0006837	Congenital Horner syndrome	2	SCN9A CL E G H	6335	243000	Indifference to pain, congenital, autosomal recessive	243000	C1855739	OMIM	1	1907	10597	603415
HP:0012332	HP:0006837	Congenital Horner syndrome	2	SLC18A2 CL E G H	6571	618049	PARKINSONISM-DYSTONIA, INFANTILE, 2	618049	CN248785	OMIM	1	124	10935	193001
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	SLC18A2 CL E G H	6571	618049	PARKINSONISM-DYSTONIA, INFANTILE, 2	618049	CN248785	OMIM	1	124	10935	193001
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	SLC18A2 CL E G H	6571	618049	PARKINSONISM-DYSTONIA, INFANTILE, 2	618049	CN248785	OMIM	1	124	10935	193001
HP:0012332	HP:0006837	Congenital Horner syndrome	2	SNCA CL E G H	6622	171695				ORPHA	1	177	11138	163890
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	SNCA CL E G H	6622	171695				ORPHA	1	177	11138	163890
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	SNCA CL E G H	6622	171695				ORPHA	1	177	11138	163890
HP:0012332	HP:0006837	Congenital Horner syndrome	2	SOX10 CL E G H	6663	609136	Peripheral demyelinating neuropathy, central dysmyelination, Waardenburg syndrome, and Hirschsprung disease	609136	C1836727	OMIM	1	302	11190	602229
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	SOX10 CL E G H	6663	609136	Peripheral demyelinating neuropathy, central dysmyelination, Waardenburg syndrome, and Hirschsprung disease	609136	C1836727	OMIM	1	302	11190	602229
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	SOX10 CL E G H	6663	609136	Peripheral demyelinating neuropathy, central dysmyelination, Waardenburg syndrome, and Hirschsprung disease	609136	C1836727	OMIM	1	302	11190	602229
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	TCF4 CL E G H	6925	610954	Pitt-Hopkins syndrome	610954	C1970431	OMIM	1	913	11634	602272
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	TCF4 CL E G H	6925	610954	Pitt-Hopkins syndrome	610954	C1970431	OMIM	1	913	11634	602272
HP:0012332	HP:0006837	Congenital Horner syndrome	2	TCF4 CL E G H	6925	610954	Pitt-Hopkins syndrome	610954	C1970431	OMIM	1	913	11634	602272
HP:0012332	HP:0006837	Congenital Horner syndrome	2	TSPYL1 CL E G H	7259	168593				ORPHA	1	48	12382	604714
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	TSPYL1 CL E G H	7259	168593				ORPHA	1	48	12382	604714
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	TSPYL1 CL E G H	7259	168593				ORPHA	1	48	12382	604714
HP:0012332	HP:0006837	Congenital Horner syndrome	2	TTR CL E G H	7276	85447				ORPHA	1	341	12405	176300
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	TTR CL E G H	7276	85447				ORPHA	1	341	12405	176300
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	TTR CL E G H	7276	85447				ORPHA	1	341	12405	176300
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	TXN2 CL E G H	25828	478029				ORPHA	1	50	17772	609063
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	TXN2 CL E G H	25828	478029				ORPHA	1	50	17772	609063
HP:0012332	HP:0006837	Congenital Horner syndrome	2	TXN2 CL E G H	25828	478029				ORPHA	1	50	17772	609063
HP:0012332	HP:0006837	Congenital Horner syndrome	2	VPS11 CL E G H	55823	466934				ORPHA	1	139	14583	608549
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	VPS11 CL E G H	55823	466934				ORPHA	1	139	14583	608549
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	VPS11 CL E G H	55823	466934				ORPHA	1	139	14583	608549
HP:0012332	HP:0006837	Congenital Horner syndrome	2	VPS11 CL E G H	55823	616683	Leukodystrophy, hypomyelinating, 12	616683	C4225247	OMIM	1	139	14583	608549
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	VPS11 CL E G H	55823	616683	Leukodystrophy, hypomyelinating, 12	616683	C4225247	OMIM	1	139	14583	608549
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	VPS11 CL E G H	55823	616683	Leukodystrophy, hypomyelinating, 12	616683	C4225247	OMIM	1	139	14583	608549
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	WDR45 CL E G H	11152	329284				ORPHA	1	504	28912	300526
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	WDR45 CL E G H	11152	329284				ORPHA	1	504	28912	300526
HP:0012332	HP:0006837	Congenital Horner syndrome	2	WDR45 CL E G H	11152	329284				ORPHA	1	504	28912	300526
HP:0012332	HP:0006837	Congenital Horner syndrome	2	WDR45 CL E G H	11152	300894	Neurodegeneration with brain iron accumulation 5	300894	C3550973	OMIM	1	504	28912	300526
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	WDR45 CL E G H	11152	300894	Neurodegeneration with brain iron accumulation 5	300894	C3550973	OMIM	1	504	28912	300526
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	WDR45 CL E G H	11152	300894	Neurodegeneration with brain iron accumulation 5	300894	C3550973	OMIM	1	504	28912	300526
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	ATXN3 CL E G H	4287	109150	Azorean disease	109150	C0024408	OMIM	0	46	7106	607047
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	CISD2 CL E G H	493856	3463				ORPHA	0	46	24212	611507
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	NR4A2 CL E G H	4929	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	112	7981	601828
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	SCN9A CL E G H	6335	133020	Primary erythromelalgia	133020	C0014805	OMIM	0	1907	10597	603415
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	SLC52A2 CL E G H	79581	97229				ORPHA	0	458	30224	607882
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	SLC52A3 CL E G H	113278	97229				ORPHA	0	399	16187	613350
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	SNCAIP CL E G H	9627	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	118	11139	603779
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	TUBB3 CL E G H	10381	300570				ORPHA	0	247	20772	602661
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	VPS13C CL E G H	54832	616840	Parkinson disease 23, autosomal recessive early-onset	616840	C4225186	OMIM	0	521	23594	608879
HP:0012332	HP:0012332	Abnormal autonomic nervous system physiology	0	WFS1 CL E G H	7466	3463				ORPHA	0	1268	12762	606201
HP:0012332	HP:0012173	Orthostatic tachycardia	1	ATXN3 CL E G H	4287	109150	Azorean disease	109150	C0024408	OMIM	0	46	7106	607047
HP:0012332	HP:0001278	Orthostatic hypotension	1	ATXN3 CL E G H	4287	109150	Azorean disease	109150	C0024408	OMIM	0	46	7106	607047
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	ATXN3 CL E G H	4287	109150	Azorean disease	109150	C0024408	OMIM	0	46	7106	607047
HP:0012332	HP:0002277	Horner syndrome	1	ATXN3 CL E G H	4287	109150	Azorean disease	109150	C0024408	OMIM	0	46	7106	607047
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	ATXN3 CL E G H	4287	109150	Azorean disease	109150	C0024408	OMIM	0	46	7106	607047
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	ATXN3 CL E G H	4287	109150	Azorean disease	109150	C0024408	OMIM	0	46	7106	607047
HP:0012332	HP:0012173	Orthostatic tachycardia	1	CISD2 CL E G H	493856	3463				ORPHA	0	46	24212	611507
HP:0012332	HP:0001278	Orthostatic hypotension	1	CISD2 CL E G H	493856	3463				ORPHA	0	46	24212	611507
HP:0012332	HP:0002277	Horner syndrome	1	CISD2 CL E G H	493856	3463				ORPHA	0	46	24212	611507
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	CISD2 CL E G H	493856	3463				ORPHA	0	46	24212	611507
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	CISD2 CL E G H	493856	3463				ORPHA	0	46	24212	611507
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	CISD2 CL E G H	493856	3463				ORPHA	0	46	24212	611507
HP:0012332	HP:0012173	Orthostatic tachycardia	1	NR4A2 CL E G H	4929	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	112	7981	601828
HP:0012332	HP:0001278	Orthostatic hypotension	1	NR4A2 CL E G H	4929	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	112	7981	601828
HP:0012332	HP:0002277	Horner syndrome	1	NR4A2 CL E G H	4929	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	112	7981	601828
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	NR4A2 CL E G H	4929	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	112	7981	601828
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	NR4A2 CL E G H	4929	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	112	7981	601828
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	NR4A2 CL E G H	4929	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	112	7981	601828
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	SCN9A CL E G H	6335	133020	Primary erythromelalgia	133020	C0014805	OMIM	0	1907	10597	603415
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	SCN9A CL E G H	6335	133020	Primary erythromelalgia	133020	C0014805	OMIM	0	1907	10597	603415
HP:0012332	HP:0001278	Orthostatic hypotension	1	SCN9A CL E G H	6335	133020	Primary erythromelalgia	133020	C0014805	OMIM	0	1907	10597	603415
HP:0012332	HP:0012173	Orthostatic tachycardia	1	SCN9A CL E G H	6335	133020	Primary erythromelalgia	133020	C0014805	OMIM	0	1907	10597	603415
HP:0012332	HP:0002277	Horner syndrome	1	SCN9A CL E G H	6335	133020	Primary erythromelalgia	133020	C0014805	OMIM	0	1907	10597	603415
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	SCN9A CL E G H	6335	133020	Primary erythromelalgia	133020	C0014805	OMIM	0	1907	10597	603415
HP:0012332	HP:0012173	Orthostatic tachycardia	1	SLC52A2 CL E G H	79581	97229				ORPHA	0	458	30224	607882
HP:0012332	HP:0001278	Orthostatic hypotension	1	SLC52A2 CL E G H	79581	97229				ORPHA	0	458	30224	607882
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	SLC52A2 CL E G H	79581	97229				ORPHA	0	458	30224	607882
HP:0012332	HP:0002277	Horner syndrome	1	SLC52A2 CL E G H	79581	97229				ORPHA	0	458	30224	607882
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	SLC52A2 CL E G H	79581	97229				ORPHA	0	458	30224	607882
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	SLC52A2 CL E G H	79581	97229				ORPHA	0	458	30224	607882
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	SLC52A3 CL E G H	113278	97229				ORPHA	0	399	16187	613350
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	SLC52A3 CL E G H	113278	97229				ORPHA	0	399	16187	613350
HP:0012332	HP:0001278	Orthostatic hypotension	1	SLC52A3 CL E G H	113278	97229				ORPHA	0	399	16187	613350
HP:0012332	HP:0012173	Orthostatic tachycardia	1	SLC52A3 CL E G H	113278	97229				ORPHA	0	399	16187	613350
HP:0012332	HP:0002277	Horner syndrome	1	SLC52A3 CL E G H	113278	97229				ORPHA	0	399	16187	613350
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	SLC52A3 CL E G H	113278	97229				ORPHA	0	399	16187	613350
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	SNCAIP CL E G H	9627	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	118	11139	603779
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	SNCAIP CL E G H	9627	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	118	11139	603779
HP:0012332	HP:0001278	Orthostatic hypotension	1	SNCAIP CL E G H	9627	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	118	11139	603779
HP:0012332	HP:0012173	Orthostatic tachycardia	1	SNCAIP CL E G H	9627	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	118	11139	603779
HP:0012332	HP:0002277	Horner syndrome	1	SNCAIP CL E G H	9627	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	118	11139	603779
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	SNCAIP CL E G H	9627	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	118	11139	603779
HP:0012332	HP:0001278	Orthostatic hypotension	1	TUBB3 CL E G H	10381	300570				ORPHA	0	247	20772	602661
HP:0012332	HP:0012173	Orthostatic tachycardia	1	TUBB3 CL E G H	10381	300570				ORPHA	0	247	20772	602661
HP:0012332	HP:0002277	Horner syndrome	1	TUBB3 CL E G H	10381	300570				ORPHA	0	247	20772	602661
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	TUBB3 CL E G H	10381	300570				ORPHA	0	247	20772	602661
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	TUBB3 CL E G H	10381	300570				ORPHA	0	247	20772	602661
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	TUBB3 CL E G H	10381	300570				ORPHA	0	247	20772	602661
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	VPS13C CL E G H	54832	616840	Parkinson disease 23, autosomal recessive early-onset	616840	C4225186	OMIM	0	521	23594	608879
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	VPS13C CL E G H	54832	616840	Parkinson disease 23, autosomal recessive early-onset	616840	C4225186	OMIM	0	521	23594	608879
HP:0012332	HP:0012173	Orthostatic tachycardia	1	VPS13C CL E G H	54832	616840	Parkinson disease 23, autosomal recessive early-onset	616840	C4225186	OMIM	0	521	23594	608879
HP:0012332	HP:0001278	Orthostatic hypotension	1	VPS13C CL E G H	54832	616840	Parkinson disease 23, autosomal recessive early-onset	616840	C4225186	OMIM	0	521	23594	608879
HP:0012332	HP:0002277	Horner syndrome	1	VPS13C CL E G H	54832	616840	Parkinson disease 23, autosomal recessive early-onset	616840	C4225186	OMIM	0	521	23594	608879
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	VPS13C CL E G H	54832	616840	Parkinson disease 23, autosomal recessive early-onset	616840	C4225186	OMIM	0	521	23594	608879
HP:0012332	HP:0012333	Abnormal sudomotor regulation	1	WFS1 CL E G H	7466	3463				ORPHA	0	1268	12762	606201
HP:0012332	HP:0008652	Autonomic erectile dysfunction	1	WFS1 CL E G H	7466	3463				ORPHA	0	1268	12762	606201
HP:0012332	HP:0001278	Orthostatic hypotension	1	WFS1 CL E G H	7466	3463				ORPHA	0	1268	12762	606201
HP:0012332	HP:0012173	Orthostatic tachycardia	1	WFS1 CL E G H	7466	3463				ORPHA	0	1268	12762	606201
HP:0012332	HP:0002277	Horner syndrome	1	WFS1 CL E G H	7466	3463				ORPHA	0	1268	12762	606201
HP:0012332	HP:0005341	Autonomic bladder dysfunction	1	WFS1 CL E G H	7466	3463				ORPHA	0	1268	12762	606201
HP:0012332	HP:0006837	Congenital Horner syndrome	2	ATXN3 CL E G H	4287	109150	Azorean disease	109150	C0024408	OMIM	0	46	7106	607047
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	ATXN3 CL E G H	4287	109150	Azorean disease	109150	C0024408	OMIM	0	46	7106	607047
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	ATXN3 CL E G H	4287	109150	Azorean disease	109150	C0024408	OMIM	0	46	7106	607047
HP:0012332	HP:0006837	Congenital Horner syndrome	2	CISD2 CL E G H	493856	3463				ORPHA	0	46	24212	611507
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	CISD2 CL E G H	493856	3463				ORPHA	0	46	24212	611507
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	CISD2 CL E G H	493856	3463				ORPHA	0	46	24212	611507
HP:0012332	HP:0006837	Congenital Horner syndrome	2	NR4A2 CL E G H	4929	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	112	7981	601828
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	NR4A2 CL E G H	4929	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	112	7981	601828
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	NR4A2 CL E G H	4929	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	112	7981	601828
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	SCN9A CL E G H	6335	133020	Primary erythromelalgia	133020	C0014805	OMIM	0	1907	10597	603415
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	SCN9A CL E G H	6335	133020	Primary erythromelalgia	133020	C0014805	OMIM	0	1907	10597	603415
HP:0012332	HP:0006837	Congenital Horner syndrome	2	SCN9A CL E G H	6335	133020	Primary erythromelalgia	133020	C0014805	OMIM	0	1907	10597	603415
HP:0012332	HP:0006837	Congenital Horner syndrome	2	SLC52A2 CL E G H	79581	97229				ORPHA	0	458	30224	607882
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	SLC52A2 CL E G H	79581	97229				ORPHA	0	458	30224	607882
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	SLC52A2 CL E G H	79581	97229				ORPHA	0	458	30224	607882
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	SLC52A3 CL E G H	113278	97229				ORPHA	0	399	16187	613350
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	SLC52A3 CL E G H	113278	97229				ORPHA	0	399	16187	613350
HP:0012332	HP:0006837	Congenital Horner syndrome	2	SLC52A3 CL E G H	113278	97229				ORPHA	0	399	16187	613350
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	SNCAIP CL E G H	9627	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	118	11139	603779
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	SNCAIP CL E G H	9627	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	118	11139	603779
HP:0012332	HP:0006837	Congenital Horner syndrome	2	SNCAIP CL E G H	9627	168600	Parkinson disease, late-onset	168600	C3160718	OMIM	0	118	11139	603779
HP:0012332	HP:0006837	Congenital Horner syndrome	2	TUBB3 CL E G H	10381	300570				ORPHA	0	247	20772	602661
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	TUBB3 CL E G H	10381	300570				ORPHA	0	247	20772	602661
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	TUBB3 CL E G H	10381	300570				ORPHA	0	247	20772	602661
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	VPS13C CL E G H	54832	616840	Parkinson disease 23, autosomal recessive early-onset	616840	C4225186	OMIM	0	521	23594	608879
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	VPS13C CL E G H	54832	616840	Parkinson disease 23, autosomal recessive early-onset	616840	C4225186	OMIM	0	521	23594	608879
HP:0012332	HP:0006837	Congenital Horner syndrome	2	VPS13C CL E G H	54832	616840	Parkinson disease 23, autosomal recessive early-onset	616840	C4225186	OMIM	0	521	23594	608879
HP:0012332	HP:0005307	Postural hypotension with compensatory tachycardia	2	WFS1 CL E G H	7466	3463				ORPHA	0	1268	12762	606201
HP:0012332	HP:0004926	Orthostatic hypotension due to autonomic dysfunction	2	WFS1 CL E G H	7466	3463				ORPHA	0	1268	12762	606201
HP:0012332	HP:0006837	Congenital Horner syndrome	2	WFS1 CL E G H	7466	3463				ORPHA	0	1268	12762	606201

Genes (69) :AAAS ARSA ASCL1 ATP7A ATXN3 B2M BRAT1 CAV1 CCT5 CISD2 COQ2 CYB561 CYP11B2 DBH DNAJC13 ECE1 EIF4G1 ELP1 FBXO7 FMR1 GABBR2 GBA GBE1 GIGYF2 GLA GMPPA HEXB IL12A IL12RB1 IRF5 LEP LEPR LIFR LMNB1 LRRK2 MMEL1 NME1 NR4A2 NTRK1 PHOX2B POLR3A POU2AF1 PRNP PSAP RET SCN11A SCN3A SCN9A SIM1 SLC18A2 SLC52A2 SLC52A3 SLC6A2 SNCA SNCAIP SOX10 SPIB TCF4 TNFSF15 TNPO3 TSPYL1 TTR TUBB3 TXN2 VPS11 VPS13C VPS35 WDR45 WFS1

Diseases (60) :231550 99803 109150 614498 139578 3463 613870 171695 93256 617903 301500 3206 601559 168600 282166 600072 615552 615548 617935 243000 133020 618049 97229 609136 610954 168593 85447 300570 478029 466934 616683 616840 329284 300894 304150 314652 606721 227510 98933 618182 610600 223360 1764 223900 263570 615510 268800 186 169500 256700 447896 604715 605543 309271 411602 66628 179494 256800 369873 105210

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.

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