Human Phenotype Ontology 
Grandparent Node:
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Neoplasm (HP:0002664)help
Parent Node:
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Neoplasm by anatomical site (HP:0011793)help
..Starting node
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Neoplasm of head and neck (HP:0012288)help
Term ID: 12288
Name: Neoplasm of head and neck
Synonym: Head and neck cancer; Head and neck tumor; Head and neck tumour
Definition: A tumor (abnormal growth of tissue) of the head and neck region with origin in the lip, oral cavity, nasal cavity, paranasal sinuses, pharynx, or larynx.
Comments:
Reference: HP:0012288
Genes and Diseases:
 
       Child Nodes:
........expandFacial neoplasm (HP:0012289) help
................... HP:0012720 Neoplasm of the nose
................... HP:0030792 Jaw neoplasm
........expandMouth neoplasm (HP:0012290) help
................... HP:0030427 Ossifying fibroma of the jaw
........expandJuvenile nasopharyngeal angiofibroma (HP:0030429) help
........expandEsophageal neoplasm (HP:0100751) help
................... HP:0011459 Esophageal carcinoma
................... HP:0031463 Esophageal squamous papilloma
................... HP:0100580 Barrett esophagus

 Sister Nodes: 
..expandHematological neoplasm (HP:0004377) help
..expandMalignant mesothelioma (HP:0100001) help
..expandNeoplasm of fatty tissue (HP:0200013) help
..expandNeoplasm of striated muscle (HP:0009728) help
..expandNeoplasm of the breast (HP:0100013) help
..expandNeoplasm of the ear (HP:0012780) help
..expandNeoplasm of the endocrine system (HP:0100568) help
..expandNeoplasm of the eye (HP:0100012) help
..expandNeoplasm of the gastrointestinal tract (HP:0007378) help
..expandNeoplasm of the genitourinary tract (HP:0007379) help
..expandNeoplasm of the heart (HP:0100544) help
..expandNeoplasm of the lip (HP:0100604) help
..expandNeoplasm of the nail (HP:0100826) help
..expandNeoplasm of the nervous system (HP:0004375) help
..expandNeoplasm of the oral cavity (HP:0100649) help
..expandNeoplasm of the pancreas (HP:0002894) help
..expandNeoplasm of the respiratory system (HP:0100606) help
..expandNeoplasm of the skeletal system (HP:0010622) help
..expandNeoplasm of the skin (HP:0008069) help
..expandNeoplasm of the thymus (HP:0100521) help
..expandRetroperitoneal chemodectomas (HP:0006729) help
..expandSoft tissue neoplasm (HP:0031459) help
..expandVascular neoplasm (HP:0100742) help
InputHPO IDHPO termDistanceGeneGene id entrezDiseaseIdDiseaseNameDiseaseMIMConceptIDSourceTypical associationHGMD variantsClinVar variantsHGNC IDGeneMIM
 
HPO disease - gene - phenotype typical associations:
HP:0012288HP:0012288Neoplasm of head and neck0FOXE1 CL E G H2304319487ORPHA1703806602617
HP:0012288HP:0012288Neoplasm of head and neck0FOXE1 CL E G H2304319487ORPHA1693806602617
HP:0012288HP:0012288Neoplasm of head and neck0HABP2 CL E G H3026319487ORPHA11964798603924
HP:0012288HP:0012288Neoplasm of head and neck0HABP2 CL E G H3026319487ORPHA11954798603924
HP:0012288HP:0012288Neoplasm of head and neck0MINPP1 CL E G H9562319487ORPHA1497102605391
HP:0012288HP:0012288Neoplasm of head and neck0MINPP1 CL E G H9562319487ORPHA1487102605391
HP:0012288HP:0012290Mouth neoplasm1FOXE1 CL E G H2304319487ORPHA1703806602617
HP:0012288HP:0100751Esophageal neoplasm1FOXE1 CL E G H2304319487ORPHA1703806602617
HP:0012288HP:0012289Facial neoplasm1FOXE1 CL E G H2304319487ORPHA1703806602617
HP:0012288HP:0100751Esophageal neoplasm1FOXE1 CL E G H2304319487ORPHA1693806602617
HP:0012288HP:0012289Facial neoplasm1FOXE1 CL E G H2304319487ORPHA1693806602617
HP:0012288HP:0012290Mouth neoplasm1FOXE1 CL E G H2304319487ORPHA1693806602617
HP:0012288HP:0030429Juvenile nasopharyngeal angiofibroma1FOXE1 CL E G H2304319487ORPHA1703806602617
HP:0012288HP:0030429Juvenile nasopharyngeal angiofibroma1FOXE1 CL E G H2304319487ORPHA1693806602617
HP:0012288HP:0012289Facial neoplasm1HABP2 CL E G H3026319487ORPHA11964798603924
HP:0012288HP:0012290Mouth neoplasm1HABP2 CL E G H3026319487ORPHA11964798603924
HP:0012288HP:0100751Esophageal neoplasm1HABP2 CL E G H3026319487ORPHA11964798603924
HP:0012288HP:0012289Facial neoplasm1HABP2 CL E G H3026319487ORPHA11954798603924
HP:0012288HP:0012290Mouth neoplasm1HABP2 CL E G H3026319487ORPHA11954798603924
HP:0012288HP:0100751Esophageal neoplasm1HABP2 CL E G H3026319487ORPHA11954798603924
HP:0012288HP:0030429Juvenile nasopharyngeal angiofibroma1HABP2 CL E G H3026319487ORPHA11964798603924
HP:0012288HP:0030429Juvenile nasopharyngeal angiofibroma1HABP2 CL E G H3026319487ORPHA11954798603924
HP:0012288HP:0012289Facial neoplasm1MINPP1 CL E G H9562319487ORPHA1497102605391
HP:0012288HP:0012290Mouth neoplasm1MINPP1 CL E G H9562319487ORPHA1497102605391
HP:0012288HP:0100751Esophageal neoplasm1MINPP1 CL E G H9562319487ORPHA1497102605391
HP:0012288HP:0012289Facial neoplasm1MINPP1 CL E G H9562319487ORPHA1487102605391
HP:0012288HP:0012290Mouth neoplasm1MINPP1 CL E G H9562319487ORPHA1487102605391
HP:0012288HP:0100751Esophageal neoplasm1MINPP1 CL E G H9562319487ORPHA1487102605391
HP:0012288HP:0030429Juvenile nasopharyngeal angiofibroma1MINPP1 CL E G H9562319487ORPHA1497102605391
HP:0012288HP:0030429Juvenile nasopharyngeal angiofibroma1MINPP1 CL E G H9562319487ORPHA1487102605391
HP:0012288HP:0011459Esophageal carcinoma2FOXE1 CL E G H2304319487ORPHA1703806602617
HP:0012288HP:0011459Esophageal carcinoma2FOXE1 CL E G H2304319487ORPHA1693806602617
HP:0012288HP:0030792Jaw neoplasm2FOXE1 CL E G H2304319487ORPHA1703806602617
HP:0012288HP:0030427Ossifying fibroma of the jaw2FOXE1 CL E G H2304319487ORPHA1703806602617
HP:0012288HP:0012720Neoplasm of the nose2FOXE1 CL E G H2304319487ORPHA1703806602617
HP:0012288HP:0100580Barrett esophagus2FOXE1 CL E G H2304319487ORPHA1703806602617
HP:0012288HP:0031463Esophageal squamous papilloma2FOXE1 CL E G H2304319487ORPHA1703806602617
HP:0012288HP:0030792Jaw neoplasm2FOXE1 CL E G H2304319487ORPHA1693806602617
HP:0012288HP:0030427Ossifying fibroma of the jaw2FOXE1 CL E G H2304319487ORPHA1693806602617
HP:0012288HP:0012720Neoplasm of the nose2FOXE1 CL E G H2304319487ORPHA1693806602617
HP:0012288HP:0100580Barrett esophagus2FOXE1 CL E G H2304319487ORPHA1693806602617
HP:0012288HP:0031463Esophageal squamous papilloma2FOXE1 CL E G H2304319487ORPHA1693806602617
HP:0012288HP:0011459Esophageal carcinoma2HABP2 CL E G H3026319487ORPHA11964798603924
HP:0012288HP:0011459Esophageal carcinoma2HABP2 CL E G H3026319487ORPHA11954798603924
HP:0012288HP:0030792Jaw neoplasm2HABP2 CL E G H3026319487ORPHA11964798603924
HP:0012288HP:0030427Ossifying fibroma of the jaw2HABP2 CL E G H3026319487ORPHA11964798603924
HP:0012288HP:0012720Neoplasm of the nose2HABP2 CL E G H3026319487ORPHA11964798603924
HP:0012288HP:0100580Barrett esophagus2HABP2 CL E G H3026319487ORPHA11964798603924
HP:0012288HP:0031463Esophageal squamous papilloma2HABP2 CL E G H3026319487ORPHA11964798603924
HP:0012288HP:0030792Jaw neoplasm2HABP2 CL E G H3026319487ORPHA11954798603924
HP:0012288HP:0030427Ossifying fibroma of the jaw2HABP2 CL E G H3026319487ORPHA11954798603924
HP:0012288HP:0012720Neoplasm of the nose2HABP2 CL E G H3026319487ORPHA11954798603924
HP:0012288HP:0100580Barrett esophagus2HABP2 CL E G H3026319487ORPHA11954798603924
HP:0012288HP:0031463Esophageal squamous papilloma2HABP2 CL E G H3026319487ORPHA11954798603924
HP:0012288HP:0011459Esophageal carcinoma2MINPP1 CL E G H9562319487ORPHA1497102605391
HP:0012288HP:0011459Esophageal carcinoma2MINPP1 CL E G H9562319487ORPHA1487102605391
HP:0012288HP:0100580Barrett esophagus2MINPP1 CL E G H9562319487ORPHA1497102605391
HP:0012288HP:0031463Esophageal squamous papilloma2MINPP1 CL E G H9562319487ORPHA1497102605391
HP:0012288HP:0030792Jaw neoplasm2MINPP1 CL E G H9562319487ORPHA1497102605391
HP:0012288HP:0030427Ossifying fibroma of the jaw2MINPP1 CL E G H9562319487ORPHA1497102605391
HP:0012288HP:0012720Neoplasm of the nose2MINPP1 CL E G H9562319487ORPHA1497102605391
HP:0012288HP:0100580Barrett esophagus2MINPP1 CL E G H9562319487ORPHA1487102605391
HP:0012288HP:0031463Esophageal squamous papilloma2MINPP1 CL E G H9562319487ORPHA1487102605391
HP:0012288HP:0030792Jaw neoplasm2MINPP1 CL E G H9562319487ORPHA1487102605391
HP:0012288HP:0030427Ossifying fibroma of the jaw2MINPP1 CL E G H9562319487ORPHA1487102605391
HP:0012288HP:0012720Neoplasm of the nose2MINPP1 CL E G H9562319487ORPHA1487102605391
HP:0012288HP:0030072Paranasal sinus neoplasm3FOXE1 CL E G H2304319487ORPHA1703806602617
HP:0012288HP:0030072Paranasal sinus neoplasm3FOXE1 CL E G H2304319487ORPHA1693806602617
HP:0012288HP:0030072Paranasal sinus neoplasm3HABP2 CL E G H3026319487ORPHA11964798603924
HP:0012288HP:0030072Paranasal sinus neoplasm3HABP2 CL E G H3026319487ORPHA11954798603924
HP:0012288HP:0030072Paranasal sinus neoplasm3MINPP1 CL E G H9562319487ORPHA1497102605391
HP:0012288HP:0030072Paranasal sinus neoplasm3MINPP1 CL E G H9562319487ORPHA1487102605391
 
HPO disease - gene - phenotype less frequent non-typical associations:


Genes (21) :APC ASCC1 CTHRC1 DLEC1 FH FOXE1 HABP2 KIT MINPP1 MSR1 PDGFRA RAD21 RHBDF2 RNF6 SDHA SDHB SDHC STAT1 STK11 TGFBR2 WWOX

Diseases (12) :319487 44890 2198 2869 247806 79665 614266 99977 523 611376 148500 391487
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.