Human Phenotype Ontology 
Grandparent Node:
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Abnormal stomach morphology (HP:0002577)help
Grandparent Node:
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Neoplasm of the gastrointestinal tract (HP:0007378)help
Parent Node:
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Neoplasm of the stomach (HP:0006753)help
..Starting node
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Stomach cancer (HP:0012126)help
Term ID: 12126
Name: Stomach cancer
Synonym: Gastric cancer
Definition: A cancer arising in any part of the stomach.
Comments:
Reference: HP:0012126
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandGastric leiomyosarcoma (HP:0031025) help
..expandGastric lymphoma (HP:0045038) help
..expandHamartomatous stomach polyps (HP:0004795) help
..expandMultiple gastric polyps (HP:0004394) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0012126HP:0012126Stomach cancer0AAGAB CL E G H7971925662ORPHA:79501Punctate palmoplantar keratoderma type 1HP:0040284 - Very rare7
HP:0012126HP:0012126Stomach cancer0APC CL E G H324583OMIM:613659Gastric cancer, somatic.3179
HP:0012126HP:0012126Stomach cancer0BLM CL E G H6411058ORPHA:125Bloom syndromeHP:0040284 - Very rare314
HP:0012126HP:0012126Stomach cancer0BMPR1A CL E G H6571076ORPHA:440437Familial colorectal cancer Type XHP:0040284 - Very rare385
HP:0012126HP:0012126Stomach cancer0BUB1 CL E G H6991148ORPHA:1052Mosaic variegated aneuploidy syndromeHP:0040283 - Occasional5
HP:0012126HP:0012126Stomach cancer0BUB1B CL E G H7011149ORPHA:1052Mosaic variegated aneuploidy syndromeHP:0040283 - Occasional76
HP:0012126HP:0012126Stomach cancer0BUB3 CL E G H91841151ORPHA:1052Mosaic variegated aneuploidy syndromeHP:0040283 - Occasional
HP:0012126HP:0012126Stomach cancer0CASP10 CL E G H8431500OMIM:613659Gastric cancer, somatic.87
HP:0012126HP:0012126Stomach cancer0CDH1 CL E G H9991748OMIM:137215Gastric cancer, hereditary diffuse.1003
HP:0012126HP:0012126Stomach cancer0CDKN2A CL E G H10291787ORPHA:524Li-Fraumeni syndromeHP:0040283 - Occasional289
HP:0012126HP:0012126Stomach cancer0CEP57 CL E G H970230794ORPHA:1052Mosaic variegated aneuploidy syndromeHP:0040283 - Occasional17
HP:0012126HP:0012126Stomach cancer0CHEK2 CL E G H1120016627ORPHA:524Li-Fraumeni syndromeHP:0040283 - Occasional833
HP:0012126HP:0012126Stomach cancer0CHEK2 CL E G H1120016627OMIM:609265LI-FRAUMENI SYNDROME 2; LFS2833
HP:0012126HP:0012126Stomach cancer0COL14A1 CL E G H73732191ORPHA:79501Punctate palmoplantar keratoderma type 1HP:0040284 - Very rare2
HP:0012126HP:0012126Stomach cancer0ERBB2 CL E G H20643430OMIM:613659Gastric cancer, somatic.77
HP:0012126HP:0012126Stomach cancer0FGFR2 CL E G H22633689OMIM:613659Gastric cancer, somatic.175
HP:0012126HP:0012126Stomach cancer0IL1B CL E G H35535992OMIM:613659Gastric cancer, somatic.2
HP:0012126HP:0012126Stomach cancer0IL1RN CL E G H35576000OMIM:613659Gastric cancer, somatic.40
HP:0012126HP:0012126Stomach cancer0IRF1 CL E G H36596116OMIM:613659Gastric cancer, somatic.2
HP:0012126HP:0012126Stomach cancer0KLF6 CL E G H13162235OMIM:613659Gastric cancer, somatic.18
HP:0012126HP:0012126Stomach cancer0KRAS CL E G H38456407OMIM:613659Gastric cancer, somatic.196
HP:0012126HP:0012126Stomach cancer0MDM2 CL E G H41936973ORPHA:524Li-Fraumeni syndromeHP:0040283 - Occasional1
HP:0012126HP:0012126Stomach cancer0MSH3 CL E G H44377326ORPHA:480536MSH3-related attenuated familial adenomatous polyposisHP:0040282 - Frequent5
HP:0012126HP:0012126Stomach cancer0MUTYH CL E G H45957527OMIM:613659Gastric cancer, somatic.592
HP:0012126HP:0012126Stomach cancer0PIK3CA CL E G H52908975OMIM:613659Gastric cancer, somatic.162
HP:0012126HP:0012126Stomach cancer0RPS20 CL E G H622410405ORPHA:440437Familial colorectal cancer Type XHP:0040284 - Very rare1
HP:0012126HP:0012126Stomach cancer0SEMA4A CL E G H6421810729ORPHA:440437Familial colorectal cancer Type XHP:0040284 - Very rare48
HP:0012126HP:0012126Stomach cancer0STK11 CL E G H679411389ORPHA:2869Peutz-Jeghers syndromeHP:0040283 - Occasional740
HP:0012126HP:0012126Stomach cancer0TP53 CL E G H715711998ORPHA:524Li-Fraumeni syndromeHP:0040283 - Occasional911
HP:0012126HP:0012126Stomach cancer0TRIP13 CL E G H931912307ORPHA:1052Mosaic variegated aneuploidy syndromeHP:0040283 - Occasional2


Genes (29) :AAGAB APC BLM BMPR1A BUB1 BUB1B BUB3 CASP10 CDH1 CDKN2A CEP57 CHEK2 COL14A1 ERBB2 FGFR2 IL1B IL1RN IRF1 KLF6 KRAS MDM2 MSH3 MUTYH PIK3CA RPS20 SEMA4A STK11 TP53 TRIP13

Diseases (10) :ORPHA:79501 OMIM:613659 ORPHA:125 ORPHA:440437 ORPHA:1052 OMIM:137215 ORPHA:524 OMIM:609265 ORPHA:480536 ORPHA:2869
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.