Human Phenotype Ontology 
Grandparent Node:
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Abnormal erythrocyte morphology (HP:0001877)help
Parent Node:
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Anemia (HP:0001903)help
..Starting node
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Anemia due to reduced life span of red cells (HP:0011895)help
Term ID: 11895
Name: Anemia due to reduced life span of red cells
Synonym: Anaemia due to reduced life span of red cells
Definition: A type of anemia related to a reduction in the average life span of red blood cells in the peripheral circulation, which is normally around 120 days.
Comments:
Reference: HP:0011895
Genes and Diseases:
 
       Child Nodes:
........expandHemolytic anemia (HP:0001878) help
................... HP:0001890 Autoimmune hemolytic anemia
................... HP:0001930 Nonspherocytic hemolytic anemia
................... HP:0001937 Microangiopathic hemolytic anemia
................... HP:0004802 Episodic hemolytic anemia
................... HP:0004804 Congenital hemolytic anemia
................... HP:0004814 Fava bean-induced hemolytic anemia
................... HP:0004817 Drug-sensitive hemolytic anemia
................... HP:0004844 Coombs-positive hemolytic anemia
................... HP:0004863 Compensated hemolytic anemia
................... HP:0004870 Chronic hemolytic anemia
................... HP:0005511 Heinz body anemia
................... HP:0005524 Macrocytic hemolytic disease
................... HP:0005525 Spontaneous hemolytic crises
................... HP:0005535 Exercise-induced hemolysis
................... HP:0008269 Increased red cell hemolysis by shear stress
................... HP:0031484 Cold-induced hemolysis
........expandIncreased red cell sickling tendency (HP:0008346) help

 Sister Nodes: 
..expandAnemia of inadequate production (HP:0010972) help
..expandRefractory anemia (HP:0005505) help
..expandTransient erythroblastopenia (HP:0005510) help
InputHPO IDHPO termDistanceGeneGene id entrezDiseaseIdDiseaseNameDiseaseMIMConceptIDSourceTypical associationHGMD variantsClinVar variantsHGNC IDGeneMIM
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0011895HP:0011895Anemia due to reduced life span of red cells0 CL E G H
HP:0011895HP:0011895Anemia due to reduced life span of red cells1 CL E G H
HP:0011895HP:0011895Anemia due to reduced life span of red cells2 CL E G H


Genes (92) :ABCB6 ABCG5 ABCG8 ADA ADAMTS13 ADAR AK1 ALDOA ANK1 ATP11C ATP7B BPGM BTNL2 CASK CASP10 CD19 CD3G CD40LG CD59 CD81 COL4A1 CPOX CR2 CTLA4 DGKE EPB41 EPB42 FAS FASLG FECH FOXP3 G6PD GALT GATA1 GCLC GP1BA GPI GPX1 GSS HBA1 HBA2 HBB HK1 HLA-DRB1 HMOX1 ICOS IL2RA KCNN4 KDM6A KMT2D KRAS LAT LCAT LRBA MS4A1 NBN NFKB1 NFKB2 NHLRC2 NLRP1 NRAS NT5C3A PFKM PGK1 PGM3 PIEZO1 PIGA PIGT PKLR PNP PRKCD RAG1 RHAG SLC2A1 SLC4A1 SPTA1 SPTB STAT1 STAT3 STIM1 TNFAIP3 TNFRSF13B TNFRSF13C TNFRSF4 TNFSF12 TPI1 TPP2 TTC7A UROD UROS WAS WIPF1

Diseases (91) :615010 612631 251066 182900 301015 277900 797 1572 308230 612300 175780 615008 611804 612690 177000 230400 79277 314050 230450 153670 231900 266130 613978 603903 614034 616689 147920 614470 617514 245900 616576 266120 232800 300653 615816 447 615399 615559 268150 185000 608885 166900 185020 611590 612653 266140 270970 616649 616744 95159 263700 906 301000 90044 210250 102700 274150 611881 222800 300908 603909 615607 121300 616100 601859 304790 613470 614164 140700 232 235700 606367 614700 647 251260 618278 617388 194380 766 266200 613179 231154 391487 614162 615952 612783 615593 615512 444463 436252 243150
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is June 2019 release.