Term ID:
1178
Name:
Ulnar claw
Synonym:
Definition:
An abnormal hand position characterized by hyperextension of the fourth and fifth fingers at the metacarpophalangeal joints and flexion of the interphalangeal joints of the same fingers such that they are curled towards the palm.
Comments:
Reference:
HP:0001178
Genes and Diseases: Child Nodes: Sister Nodes: ..Abnormal carpal morphology (HP:0001191) ..Abnormal hand bone ossification (HP:0010660) ..Abnormal hand cortical bone morphology (HP:0005926) ..Abnormal hand diaphysis morphology (HP:0005925) ..Abnormal hand epiphysis morphology (HP:0005924) ..Abnormal hand metaphysis morphology (HP:0005923) ..Abnormal hand morphology (HP:0005922) ..Abnormal palm morphology (HP:0100871) ..Abnormality of dorsoventral patterning of the limbs (HP:0100270) ..Abnormality of finger (HP:0001167) ..Abnormality of hand joint mobility (HP:0006256) ..Abnormality of the metacarpal bones (HP:0001163) ..Abnormality of the musculature of the hand (HP:0001421) ..Aplasia/hypoplasia involving bones of the hand (HP:0005927) ..Autoamputation of digits (HP:0007460) ..Decreased finger mobility (HP:0006135) ..Deviation of the hand or of fingers of the hand (HP:0009484) ..Duplication of hand bones (HP:0004275) ..Exostoses of hand bones (HP:0004276) ..Fractured hand bones (HP:0004277) ..Joint contracture of the hand (HP:0009473) ..Osteolytic defects of the hand bones (HP:0009699) ..Short tubular bones of the hand (HP:0001248) ..Split hand (HP:0001171) ..Synostosis involving bones of the hand (HP:0004278) Input HPO ID HPO term Distance Gene Gene id entrez HGNC ID DiseaseId DiseaseName Frequency Onset HGMD variants ClinVar variants HPO disease - gene - phenotype typical associations: HPO disease - gene - phenotype less frequent non-typical associations: HP:0001178 HP:0001178 Ulnar claw 0 EGR2 CL E G H 1959 3239 OMIM:145900 Hypertrophic neuropathy of dejerine-sottas . 58 HP:0001178 HP:0001178 Ulnar claw 0 GDAP1 CL E G H 54332 15968 OMIM:607706 Charcot-Marie-Tooth disease, axonal, with vocal cord paresis, autosomalrecessive 108 HP:0001178 HP:0001178 Ulnar claw 0 GDAP1 CL E G H 54332 15968 OMIM:608340 Charcot-Marie-Tooth disease, recessive intermediate A . 108 HP:0001178 HP:0001178 Ulnar claw 0 GDAP1 CL E G H 54332 15968 OMIM:214400 Charcot-Marie-Tooth disease, type 4A . 108 HP:0001178 HP:0001178 Ulnar claw 0 HSPB1 CL E G H 3315 5246 OMIM:606595 Charcot-Marie-Tooth disease, axonal, type 2F . 47 HP:0001178 HP:0001178 Ulnar claw 0 MPV17 CL E G H 4358 7224 OMIM:618400 Charcot-Marie-Tooth disease, axonal, type 2EE 56 HP:0001178 HP:0001178 Ulnar claw 0 MPZ CL E G H 4359 7225 OMIM:118200 Charcot-Marie-Tooth disease, demyelinating, type 1B . 134 HP:0001178 HP:0001178 Ulnar claw 0 MPZ CL E G H 4359 7225 OMIM:145900 Hypertrophic neuropathy of dejerine-sottas . 134 HP:0001178 HP:0001178 Ulnar claw 0 NEFL CL E G H 4747 7739 OMIM:607684 Charcot-Marie-Tooth disease, axonal, type 2E . 118 HP:0001178 HP:0001178 Ulnar claw 0 PMP22 CL E G H 5376 9118 OMIM:118220 Charcot-Marie-Tooth disease, demyelinating, type 1A . 79 HP:0001178 HP:0001178 Ulnar claw 0 PMP22 CL E G H 5376 9118 OMIM:145900 Hypertrophic neuropathy of dejerine-sottas . 79 HP:0001178 HP:0001178 Ulnar claw 0 PRX CL E G H 57716 13797 OMIM:145900 Hypertrophic neuropathy of dejerine-sottas . 170 HP:0001178 HP:0001178 Ulnar claw 0 SBF2 CL E G H 81846 2135 OMIM:604563 Charcot-Marie-Tooth disease, type 4B2 . 180
Genes (9) :EGR2 GDAP1 HSPB1 MPV17 MPZ NEFL PMP22 PRX SBF2 Diseases (10) :OMIM:145900 OMIM:607706 OMIM:608340 OMIM:214400 OMIM:606595 OMIM:618400 OMIM:118200 OMIM:607684 OMIM:118220 OMIM:604563
Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.