Human Phenotype Ontology 
Grandparent Node:
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Abnormality of the upper limb (HP:0002817)help
Parent Node:
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Abnormality of the hand (HP:0001155)help
..Starting node
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Ulnar claw (HP:0001178)help
Term ID: 1178
Name: Ulnar claw
Synonym:
Definition: An abnormal hand position characterized by hyperextension of the fourth and fifth fingers at the metacarpophalangeal joints and flexion of the interphalangeal joints of the same fingers such that they are curled towards the palm.
Comments:
Reference: HP:0001178
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAbnormal carpal morphology (HP:0001191) help
..expandAbnormal hand bone ossification (HP:0010660) help
..expandAbnormal hand cortical bone morphology (HP:0005926) help
..expandAbnormal hand diaphysis morphology (HP:0005925) help
..expandAbnormal hand epiphysis morphology (HP:0005924) help
..expandAbnormal hand metaphysis morphology (HP:0005923) help
..expandAbnormal hand morphology (HP:0005922) help
..expandAbnormal palm morphology (HP:0100871) help
..expandAbnormality of dorsoventral patterning of the limbs (HP:0100270) help
..expandAbnormality of finger (HP:0001167) help
..expandAbnormality of hand joint mobility (HP:0006256) help
..expandAbnormality of the metacarpal bones (HP:0001163) help
..expandAbnormality of the musculature of the hand (HP:0001421) help
..expandAplasia/hypoplasia involving bones of the hand (HP:0005927) help
..expandAutoamputation of digits (HP:0007460) help
..expandDecreased finger mobility (HP:0006135) help
..expandDeviation of the hand or of fingers of the hand (HP:0009484) help
..expandDuplication of hand bones (HP:0004275) help
..expandExostoses of hand bones (HP:0004276) help
..expandFractured hand bones (HP:0004277) help
..expandJoint contracture of the hand (HP:0009473) help
..expandOsteolytic defects of the hand bones (HP:0009699) help
..expandShort tubular bones of the hand (HP:0001248) help
..expandSplit hand (HP:0001171) help
..expandSynostosis involving bones of the hand (HP:0004278) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0001178HP:0001178Ulnar claw0EGR2 CL E G H19593239OMIM:145900Hypertrophic neuropathy of dejerine-sottas.58
HP:0001178HP:0001178Ulnar claw0GDAP1 CL E G H5433215968OMIM:607706Charcot-Marie-Tooth disease, axonal, with vocal cord paresis, autosomalrecessive108
HP:0001178HP:0001178Ulnar claw0GDAP1 CL E G H5433215968OMIM:608340Charcot-Marie-Tooth disease, recessive intermediate A.108
HP:0001178HP:0001178Ulnar claw0GDAP1 CL E G H5433215968OMIM:214400Charcot-Marie-Tooth disease, type 4A.108
HP:0001178HP:0001178Ulnar claw0HSPB1 CL E G H33155246OMIM:606595Charcot-Marie-Tooth disease, axonal, type 2F.47
HP:0001178HP:0001178Ulnar claw0MPV17 CL E G H43587224OMIM:618400Charcot-Marie-Tooth disease, axonal, type 2EE56
HP:0001178HP:0001178Ulnar claw0MPZ CL E G H43597225OMIM:118200Charcot-Marie-Tooth disease, demyelinating, type 1B.134
HP:0001178HP:0001178Ulnar claw0MPZ CL E G H43597225OMIM:145900Hypertrophic neuropathy of dejerine-sottas.134
HP:0001178HP:0001178Ulnar claw0NEFL CL E G H47477739OMIM:607684Charcot-Marie-Tooth disease, axonal, type 2E.118
HP:0001178HP:0001178Ulnar claw0PMP22 CL E G H53769118OMIM:118220Charcot-Marie-Tooth disease, demyelinating, type 1A.79
HP:0001178HP:0001178Ulnar claw0PMP22 CL E G H53769118OMIM:145900Hypertrophic neuropathy of dejerine-sottas.79
HP:0001178HP:0001178Ulnar claw0PRX CL E G H5771613797OMIM:145900Hypertrophic neuropathy of dejerine-sottas.170
HP:0001178HP:0001178Ulnar claw0SBF2 CL E G H818462135OMIM:604563Charcot-Marie-Tooth disease, type 4B2.180


Genes (9) :EGR2 GDAP1 HSPB1 MPV17 MPZ NEFL PMP22 PRX SBF2

Diseases (10) :OMIM:145900 OMIM:607706 OMIM:608340 OMIM:214400 OMIM:606595 OMIM:618400 OMIM:118200 OMIM:607684 OMIM:118220 OMIM:604563
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.