Human Phenotype Ontology 
Grandparent Node:
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Neurodevelopmental delay (HP:0012758)help
Parent Node:
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Motor delay (HP:0001270)help
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Delayed fine motor development (HP:0010862)help
Term ID: 10862
Name: Delayed fine motor development
Synonym:
Definition: A type of motor delay characterized by a delay in acquiring the ability to control the fingers and hands.
Comments:
Reference: HP:0010862
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandDelayed gross motor development (HP:0002194) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0010862HP:0010862Delayed fine motor development0APC2 CL E G H1029724036OMIM:618677CORTICAL DYSPLASIA, COMPLEX, WITH OTHER BRAIN MALFORMATIONS 10; CDCBM101
HP:0010862HP:0010862Delayed fine motor development0AUTS2 CL E G H2605314262OMIM:615834Mental retardation, autosomal dominant 2661
HP:0010862HP:0010862Delayed fine motor development0CARS1 CL E G H8331493OMIM:618891MICROCEPHALY, DEVELOPMENTAL DELAY, AND BRITTLE HAIR SYNDROME; MDBH
HP:0010862HP:0010862Delayed fine motor development0CDC40 CL E G H5136217350OMIM:619302PONTOCEREBELLAR HYPOPLASIA, TYPE 15; PCH15
HP:0010862HP:0010862Delayed fine motor development0CDH11 CL E G H10091750OMIM:211380Elsahy-Waters syndrome2
HP:0010862HP:0010862Delayed fine motor development0CDH2 CL E G H10001759OMIM:618929AGENESIS OF CORPUS CALLOSUM, CARDIAC, OCULAR, AND GENITAL SYNDROME; ACOGS
HP:0010862HP:0010862Delayed fine motor development0CLCN3 CL E G H11822021OMIM:619512NEURODEVELOPMENTAL DISORDER WITH HYPOTONIA AND BRAIN ABNORMALITIES; NEDHYBA2
HP:0010862HP:0010862Delayed fine motor development0CLCN3 CL E G H11822021OMIM:619517NEURODEVELOPMENTAL DISORDER WITH SEIZURES AND BRAIN ABNORMALITIES; NEDSBA2
HP:0010862HP:0010862Delayed fine motor development0CLCN7 CL E G H11862025OMIM:618541Hypopigmentation, organomegaly, and delayed myelination and development.102
HP:0010862HP:0010862Delayed fine motor development0CLP1 CL E G H1097816999ORPHA:411493Pontocerebellar hypoplasia type 10HP:0040281 - Very frequent7
HP:0010862HP:0010862Delayed fine motor development0CNOT3 CL E G H48497879OMIM:618672INTELLECTUAL DEVELOPMENTAL DISORDER WITH SPEECH DELAY, AUTISM, AND DYSMORPHIC FACIES; IDDSADF
HP:0010862HP:0010862Delayed fine motor development0COL12A1 CL E G H13032188ORPHA:536516Myopathic Ehlers-Danlos syndromeHP:0040283 - Occasional65
HP:0010862HP:0010862Delayed fine motor development0DPH2 CL E G H18023004OMIM:620062
HP:0010862HP:0010862Delayed fine motor development0EBF3 CL E G H25373819087OMIM:617330HYPOTONIA, ATAXIA, AND DELAYED DEVELOPMENT SYNDROME; HADDS25
HP:0010862HP:0010862Delayed fine motor development0FDXR CL E G H22323642ORPHA:543470Optic atrophy-ataxia-peripheral neuropathy-global developmental delay syndromeHP:0040281 - Very frequent
HP:0010862HP:0010862Delayed fine motor development0FIG4 CL E G H989616873ORPHA:208441Bilateral parasagittal parieto-occipital polymicrogyriaHP:0040281 - Very frequent111
HP:0010862HP:0010862Delayed fine motor development0FNIP1 CL E G H9645929418OMIM:619705IMMUNODEFICIENCY 93 AND HYPERTROPHIC CARDIOMYOPATHY; IMD931
HP:0010862HP:0010862Delayed fine motor development0GRIA1 CL E G H28904571OMIM:6199273
HP:0010862HP:0010862Delayed fine motor development0GRIA1 CL E G H28904571OMIM:6199313
HP:0010862HP:0010862Delayed fine motor development0ITPR1 CL E G H37086180ORPHA:208513Spinocerebellar ataxia type 29HP:0040281 - Very frequent177
HP:0010862HP:0010862Delayed fine motor development0KAT8 CL E G H8414817933OMIM:618974LI-GHORBANI-WEISZ-HUBSHMAN SYNDROME; LIGOWS
HP:0010862HP:0010862Delayed fine motor development0KCNK4 CL E G H508016279OMIM:618381Facial dysmorphism, hypertrichosis, epilepsy, intellectual/developmental delay, and gingival overgrowth syndrome
HP:0010862HP:0010862Delayed fine motor development0KDM4B CL E G H2303029136OMIM:619320INTELLECTUAL DEVELOPMENTAL DISORDER, AUTOSOMAL DOMINANT 65; MRD65
HP:0010862HP:0010862Delayed fine motor development0MINPP1 CL E G H95627102OMIM:619527PONTOCEREBELLAR HYPOPLASIA, TYPE 16; PCH163
HP:0010862HP:0010862Delayed fine motor development0NDST1 CL E G H33407680OMIM:616116Mental retardation, autosomal recessive 4627
HP:0010862HP:0010862Delayed fine motor development0PI4KA CL E G H52978983OMIM:619708GASTROINTESTINAL DEFECTS AND IMMUNODEFICIENCY SYNDROME 2; GIDID211
HP:0010862HP:0010862Delayed fine motor development0POR CL E G H54479208ORPHA:95699Congenital adrenal hyperplasia due to cytochrome P450 oxidoreductase deficiencyHP:0040283 - Occasional76
HP:0010862HP:0010862Delayed fine motor development0SIN3A CL E G H2594219353OMIM:613406Witteveen-Kolk syndrome9
HP:0010862HP:0010862Delayed fine motor development0SNX14 CL E G H5723114977ORPHA:397709Intellectual disability-coarse face-macrocephaly-cerebellar hypotrophy syndromeHP:0040281 - Very frequent14
HP:0010862HP:0010862Delayed fine motor development0SNX14 CL E G H5723114977OMIM:616354Spinocerebellar ataxia, autosomal recessive 2014
HP:0010862HP:0010862Delayed fine motor development0SPTBN1 CL E G H671111275OMIM:619475DEVELOPMENTAL DELAY, IMPAIRED SPEECH, AND BEHAVIORAL ABNORMALITIES; DDISBA
HP:0010862HP:0010862Delayed fine motor development0TET3 CL E G H20042428313OMIM:618798BECK-FAHRNER SYNDROME; BEFAHRS
HP:0010862HP:0010862Delayed fine motor development0TMTC3 CL E G H16041826899OMIM:617255Lissencephaly 85
HP:0010862HP:0010862Delayed fine motor development0TNRC6B CL E G H2311229190OMIM:619243GLOBAL DEVELOPMENTAL DELAY WITH SPEECH AND BEHAVIORAL ABNORMALITIES; GDSBA
HP:0010862HP:0010862Delayed fine motor development0TRAPPC6B CL E G H12255323066OMIM:617862Neurodevelopmental disorder with microcephaly, epilepsy, and brain atrophy
HP:0010862HP:0010862Delayed fine motor development0TRRAP CL E G H829512347OMIM:618454Developmental delay with or without dysmorphic facies and autism2
HP:0010862HP:0010862Delayed fine motor development0TSEN15 CL E G H11646116791OMIM:617026Pontocerebellar hypoplasia, type 2F3
HP:0010862HP:0010862Delayed fine motor development0TUBB3 CL E G H1038120772ORPHA:300570Cortical dysgenesis with pontocerebellar hypoplasia due to TUBB3 mutationHP:0040282 - Frequent64
HP:0010862HP:0010862Delayed fine motor development0WASHC4 CL E G H2332529174OMIM:615817Mental retardation, autosomal recessive 4325
HP:0010862HP:0010862Delayed fine motor development0WLS CL E G H7997130238OMIM:619648ZAKI SYNDROME; ZKS


Genes (37) :APC2 AUTS2 CARS1 CDC40 CDH11 CDH2 CLCN3 CLCN7 CLP1 CNOT3 COL12A1 DPH2 EBF3 FDXR FIG4 FNIP1 GRIA1 ITPR1 KAT8 KCNK4 KDM4B MINPP1 NDST1 PI4KA POR SIN3A SNX14 SPTBN1 TET3 TMTC3 TNRC6B TRAPPC6B TRRAP TSEN15 TUBB3 WASHC4 WLS

Diseases (40) :OMIM:618677 OMIM:615834 OMIM:618891 OMIM:619302 OMIM:211380 OMIM:618929 OMIM:619512 OMIM:619517 OMIM:618541 ORPHA:411493 OMIM:618672 ORPHA:536516 OMIM:620062 OMIM:617330 ORPHA:543470 ORPHA:208441 OMIM:619705 OMIM:619927 OMIM:619931 ORPHA:208513 OMIM:618974 OMIM:618381 OMIM:619320 OMIM:619527 OMIM:616116 OMIM:619708 ORPHA:95699 OMIM:613406 ORPHA:397709 OMIM:616354 OMIM:619475 OMIM:618798 OMIM:617255 OMIM:619243 OMIM:617862 OMIM:618454 OMIM:617026 ORPHA:300570 OMIM:615817 OMIM:619648
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.