Human Phenotype Ontology 
Grandparent Node:
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Abnormality of male external genitalia (HP:0000032)help
Grandparent Node:
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Genital neoplasm (HP:0010787)help
Parent Node:
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Abnormal testis morphology (HP:0000035)help
Parent Node:
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Gonadal neoplasm (HP:0010785)help
Parent Node:
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Neoplasm of the male external genitalia (HP:0100848)help
..Starting node
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Testicular neoplasm (HP:0010788)help
Term ID: 10788
Name: Testicular neoplasm
Synonym: Testicular cancer; Testicular neoplasia; Testicular tumor; Testicular tumour
Definition: The presence of a neoplasm of the testis.
Comments:
Reference: HP:0010788
Genes and Diseases:
 
       Child Nodes:
........expandTesticular gonadoblastoma (HP:0000030) help
........expandTesticular adrenal rest tumor (HP:0025451) help
........expandTesticular mesothelioma (HP:0100005) help
........expandTesticular teratoma (HP:0100616) help
........expandTesticular seminoma (HP:0100617) help
........expandLeydig cell neoplasia (HP:0100618) help
........expandSertoli cell neoplasm (HP:0100619) help
................... HP:0008204 Precocious puberty with Sertoli cell tumor

 Sister Nodes: 
..expandNeoplasm of the penis (HP:0100850) help
..expandNeoplasm of the scrotum (HP:0100849) help
InputHPO IDHPO termDistanceGeneGene id entrezDiseaseIdDiseaseNameDiseaseMIMConceptIDSourceTypical associationHGMD variantsClinVar variantsHGNC IDGeneMIM
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0010788HP:0010788Testicular neoplasm0AKT1 CL E G H207744Aortic valves stenosis of the childORPHA0417391164730
HP:0010788HP:0010788Testicular neoplasm0AKT1 CL E G H207744Aortic valves stenosis of the childORPHA0380391164730
HP:0010788HP:0010788Testicular neoplasm0CDC73 CL E G H7957799880ORPHA082816783607393
HP:0010788HP:0010788Testicular neoplasm0CDC73 CL E G H79577143ORPHA082816783607393
HP:0010788HP:0010788Testicular neoplasm0CDC73 CL E G H7957799880ORPHA070416783607393
HP:0010788HP:0010788Testicular neoplasm0CDC73 CL E G H79577143ORPHA070416783607393
HP:0010788HP:0010788Testicular neoplasm0CDKN1B CL E G H1027276152ORPHA05071785600778
HP:0010788HP:0010788Testicular neoplasm0CDKN1B CL E G H1027276152ORPHA05961785600778
HP:0010788HP:0010788Testicular neoplasm0EWSR1 CL E G H213083469ORPHA0623508133450
HP:0010788HP:0010788Testicular neoplasm0EWSR1 CL E G H213083469ORPHA0603508133450
HP:0010788HP:0010788Testicular neoplasm0GNAS CL E G H2778562ORPHA03334392139320
HP:0010788HP:0010788Testicular neoplasm0GNAS CL E G H2778562ORPHA03714392139320
HP:0010788HP:0010788Testicular neoplasm0PTEN CL E G H5728744Aortic valves stenosis of the childORPHA022469588601728
HP:0010788HP:0010788Testicular neoplasm0PTEN CL E G H5728744Aortic valves stenosis of the childORPHA024169588601728
HP:0010788HP:0010788Testicular neoplasm0WT1 CL E G H749083469ORPHA087312796607102
HP:0010788HP:0010788Testicular neoplasm0WT1 CL E G H749083469ORPHA0101812796607102
HP:0010788HP:0100005Testicular mesothelioma1AKT1 CL E G H207744Aortic valves stenosis of the childORPHA0380391164730
HP:0010788HP:0100616Testicular teratoma1AKT1 CL E G H207744Aortic valves stenosis of the childORPHA0380391164730
HP:0010788HP:0100618Leydig cell neoplasia1AKT1 CL E G H207744Aortic valves stenosis of the childORPHA0380391164730
HP:0010788HP:0025451Testicular adrenal rest tumor1AKT1 CL E G H207744Aortic valves stenosis of the childORPHA0380391164730
HP:0010788HP:0000030Testicular gonadoblastoma1AKT1 CL E G H207744Aortic valves stenosis of the childORPHA0417391164730
HP:0010788HP:0100617Testicular seminoma1AKT1 CL E G H207744Aortic valves stenosis of the childORPHA0417391164730
HP:0010788HP:0100619Sertoli cell neoplasm1AKT1 CL E G H207744Aortic valves stenosis of the childORPHA0417391164730
HP:0010788HP:0100617Testicular seminoma1AKT1 CL E G H207744Aortic valves stenosis of the childORPHA0380391164730
HP:0010788HP:0100619Sertoli cell neoplasm1AKT1 CL E G H207744Aortic valves stenosis of the childORPHA0380391164730
HP:0010788HP:0000030Testicular gonadoblastoma1AKT1 CL E G H207744Aortic valves stenosis of the childORPHA0380391164730
HP:0010788HP:0100005Testicular mesothelioma1AKT1 CL E G H207744Aortic valves stenosis of the childORPHA0417391164730
HP:0010788HP:0100616Testicular teratoma1AKT1 CL E G H207744Aortic valves stenosis of the childORPHA0417391164730
HP:0010788HP:0100618Leydig cell neoplasia1AKT1 CL E G H207744Aortic valves stenosis of the childORPHA0417391164730
HP:0010788HP:0025451Testicular adrenal rest tumor1AKT1 CL E G H207744Aortic valves stenosis of the childORPHA0417391164730
HP:0010788HP:0100005Testicular mesothelioma1CDC73 CL E G H79577143ORPHA070416783607393
HP:0010788HP:0100616Testicular teratoma1CDC73 CL E G H7957799880ORPHA070416783607393
HP:0010788HP:0100616Testicular teratoma1CDC73 CL E G H79577143ORPHA070416783607393
HP:0010788HP:0100618Leydig cell neoplasia1CDC73 CL E G H7957799880ORPHA070416783607393
HP:0010788HP:0100618Leydig cell neoplasia1CDC73 CL E G H79577143ORPHA070416783607393
HP:0010788HP:0025451Testicular adrenal rest tumor1CDC73 CL E G H7957799880ORPHA070416783607393
HP:0010788HP:0025451Testicular adrenal rest tumor1CDC73 CL E G H79577143ORPHA070416783607393
HP:0010788HP:0100005Testicular mesothelioma1CDC73 CL E G H7957799880ORPHA070416783607393
HP:0010788HP:0000030Testicular gonadoblastoma1CDC73 CL E G H79577143ORPHA082816783607393
HP:0010788HP:0100617Testicular seminoma1CDC73 CL E G H7957799880ORPHA082816783607393
HP:0010788HP:0100617Testicular seminoma1CDC73 CL E G H79577143ORPHA082816783607393
HP:0010788HP:0100619Sertoli cell neoplasm1CDC73 CL E G H7957799880ORPHA082816783607393
HP:0010788HP:0100619Sertoli cell neoplasm1CDC73 CL E G H79577143ORPHA082816783607393
HP:0010788HP:0000030Testicular gonadoblastoma1CDC73 CL E G H7957799880ORPHA082816783607393
HP:0010788HP:0000030Testicular gonadoblastoma1CDC73 CL E G H79577143ORPHA070416783607393
HP:0010788HP:0100617Testicular seminoma1CDC73 CL E G H7957799880ORPHA070416783607393
HP:0010788HP:0100617Testicular seminoma1CDC73 CL E G H79577143ORPHA070416783607393
HP:0010788HP:0100619Sertoli cell neoplasm1CDC73 CL E G H7957799880ORPHA070416783607393
HP:0010788HP:0100619Sertoli cell neoplasm1CDC73 CL E G H79577143ORPHA070416783607393
HP:0010788HP:0000030Testicular gonadoblastoma1CDC73 CL E G H7957799880ORPHA070416783607393
HP:0010788HP:0025451Testicular adrenal rest tumor1CDC73 CL E G H79577143ORPHA082816783607393
HP:0010788HP:0100005Testicular mesothelioma1CDC73 CL E G H7957799880ORPHA082816783607393
HP:0010788HP:0100005Testicular mesothelioma1CDC73 CL E G H79577143ORPHA082816783607393
HP:0010788HP:0100616Testicular teratoma1CDC73 CL E G H7957799880ORPHA082816783607393
HP:0010788HP:0100616Testicular teratoma1CDC73 CL E G H79577143ORPHA082816783607393
HP:0010788HP:0100618Leydig cell neoplasia1CDC73 CL E G H7957799880ORPHA082816783607393
HP:0010788HP:0100618Leydig cell neoplasia1CDC73 CL E G H79577143ORPHA082816783607393
HP:0010788HP:0025451Testicular adrenal rest tumor1CDC73 CL E G H7957799880ORPHA082816783607393
HP:0010788HP:0100617Testicular seminoma1CDKN1B CL E G H1027276152ORPHA05071785600778
HP:0010788HP:0100619Sertoli cell neoplasm1CDKN1B CL E G H1027276152ORPHA05071785600778
HP:0010788HP:0000030Testicular gonadoblastoma1CDKN1B CL E G H1027276152ORPHA05071785600778
HP:0010788HP:0100616Testicular teratoma1CDKN1B CL E G H1027276152ORPHA05961785600778
HP:0010788HP:0100618Leydig cell neoplasia1CDKN1B CL E G H1027276152ORPHA05961785600778
HP:0010788HP:0025451Testicular adrenal rest tumor1CDKN1B CL E G H1027276152ORPHA05961785600778
HP:0010788HP:0100005Testicular mesothelioma1CDKN1B CL E G H1027276152ORPHA05961785600778
HP:0010788HP:0100616Testicular teratoma1CDKN1B CL E G H1027276152ORPHA05071785600778
HP:0010788HP:0100618Leydig cell neoplasia1CDKN1B CL E G H1027276152ORPHA05071785600778
HP:0010788HP:0025451Testicular adrenal rest tumor1CDKN1B CL E G H1027276152ORPHA05071785600778
HP:0010788HP:0100005Testicular mesothelioma1CDKN1B CL E G H1027276152ORPHA05071785600778
HP:0010788HP:0100617Testicular seminoma1CDKN1B CL E G H1027276152ORPHA05961785600778
HP:0010788HP:0100619Sertoli cell neoplasm1CDKN1B CL E G H1027276152ORPHA05961785600778
HP:0010788HP:0000030Testicular gonadoblastoma1CDKN1B CL E G H1027276152ORPHA05961785600778
HP:0010788HP:0100005Testicular mesothelioma1EWSR1 CL E G H213083469ORPHA0603508133450
HP:0010788HP:0100616Testicular teratoma1EWSR1 CL E G H213083469ORPHA0603508133450
HP:0010788HP:0100618Leydig cell neoplasia1EWSR1 CL E G H213083469ORPHA0603508133450
HP:0010788HP:0025451Testicular adrenal rest tumor1EWSR1 CL E G H213083469ORPHA0603508133450
HP:0010788HP:0100617Testicular seminoma1EWSR1 CL E G H213083469ORPHA0623508133450
HP:0010788HP:0100619Sertoli cell neoplasm1EWSR1 CL E G H213083469ORPHA0623508133450
HP:0010788HP:0000030Testicular gonadoblastoma1EWSR1 CL E G H213083469ORPHA0623508133450
HP:0010788HP:0100617Testicular seminoma1EWSR1 CL E G H213083469ORPHA0603508133450
HP:0010788HP:0100619Sertoli cell neoplasm1EWSR1 CL E G H213083469ORPHA0603508133450
HP:0010788HP:0000030Testicular gonadoblastoma1EWSR1 CL E G H213083469ORPHA0603508133450
HP:0010788HP:0100005Testicular mesothelioma1EWSR1 CL E G H213083469ORPHA0623508133450
HP:0010788HP:0100616Testicular teratoma1EWSR1 CL E G H213083469ORPHA0623508133450
HP:0010788HP:0100618Leydig cell neoplasia1EWSR1 CL E G H213083469ORPHA0623508133450
HP:0010788HP:0025451Testicular adrenal rest tumor1EWSR1 CL E G H213083469ORPHA0623508133450
HP:0010788HP:0000030Testicular gonadoblastoma1GNAS CL E G H2778562ORPHA03334392139320
HP:0010788HP:0100617Testicular seminoma1GNAS CL E G H2778562ORPHA03334392139320
HP:0010788HP:0100619Sertoli cell neoplasm1GNAS CL E G H2778562ORPHA03334392139320
HP:0010788HP:0100005Testicular mesothelioma1GNAS CL E G H2778562ORPHA03714392139320
HP:0010788HP:0100616Testicular teratoma1GNAS CL E G H2778562ORPHA03714392139320
HP:0010788HP:0100618Leydig cell neoplasia1GNAS CL E G H2778562ORPHA03714392139320
HP:0010788HP:0025451Testicular adrenal rest tumor1GNAS CL E G H2778562ORPHA03714392139320
HP:0010788HP:0100005Testicular mesothelioma1GNAS CL E G H2778562ORPHA03334392139320
HP:0010788HP:0100616Testicular teratoma1GNAS CL E G H2778562ORPHA03334392139320
HP:0010788HP:0100618Leydig cell neoplasia1GNAS CL E G H2778562ORPHA03334392139320
HP:0010788HP:0025451Testicular adrenal rest tumor1GNAS CL E G H2778562ORPHA03334392139320
HP:0010788HP:0000030Testicular gonadoblastoma1GNAS CL E G H2778562ORPHA03714392139320
HP:0010788HP:0100617Testicular seminoma1GNAS CL E G H2778562ORPHA03714392139320
HP:0010788HP:0100619Sertoli cell neoplasm1GNAS CL E G H2778562ORPHA03714392139320
HP:0010788HP:0100617Testicular seminoma1PTEN CL E G H5728744Aortic valves stenosis of the childORPHA022469588601728
HP:0010788HP:0100619Sertoli cell neoplasm1PTEN CL E G H5728744Aortic valves stenosis of the childORPHA022469588601728
HP:0010788HP:0000030Testicular gonadoblastoma1PTEN CL E G H5728744Aortic valves stenosis of the childORPHA022469588601728
HP:0010788HP:0100005Testicular mesothelioma1PTEN CL E G H5728744Aortic valves stenosis of the childORPHA024169588601728
HP:0010788HP:0100616Testicular teratoma1PTEN CL E G H5728744Aortic valves stenosis of the childORPHA024169588601728
HP:0010788HP:0100618Leydig cell neoplasia1PTEN CL E G H5728744Aortic valves stenosis of the childORPHA024169588601728
HP:0010788HP:0025451Testicular adrenal rest tumor1PTEN CL E G H5728744Aortic valves stenosis of the childORPHA024169588601728
HP:0010788HP:0100005Testicular mesothelioma1PTEN CL E G H5728744Aortic valves stenosis of the childORPHA022469588601728
HP:0010788HP:0100616Testicular teratoma1PTEN CL E G H5728744Aortic valves stenosis of the childORPHA022469588601728
HP:0010788HP:0100618Leydig cell neoplasia1PTEN CL E G H5728744Aortic valves stenosis of the childORPHA022469588601728
HP:0010788HP:0025451Testicular adrenal rest tumor1PTEN CL E G H5728744Aortic valves stenosis of the childORPHA022469588601728
HP:0010788HP:0000030Testicular gonadoblastoma1PTEN CL E G H5728744Aortic valves stenosis of the childORPHA024169588601728
HP:0010788HP:0100617Testicular seminoma1PTEN CL E G H5728744Aortic valves stenosis of the childORPHA024169588601728
HP:0010788HP:0100619Sertoli cell neoplasm1PTEN CL E G H5728744Aortic valves stenosis of the childORPHA024169588601728
HP:0010788HP:0100617Testicular seminoma1WT1 CL E G H749083469ORPHA087312796607102
HP:0010788HP:0100619Sertoli cell neoplasm1WT1 CL E G H749083469ORPHA087312796607102
HP:0010788HP:0000030Testicular gonadoblastoma1WT1 CL E G H749083469ORPHA087312796607102
HP:0010788HP:0100005Testicular mesothelioma1WT1 CL E G H749083469ORPHA0101812796607102
HP:0010788HP:0100616Testicular teratoma1WT1 CL E G H749083469ORPHA0101812796607102
HP:0010788HP:0100618Leydig cell neoplasia1WT1 CL E G H749083469ORPHA0101812796607102
HP:0010788HP:0025451Testicular adrenal rest tumor1WT1 CL E G H749083469ORPHA0101812796607102
HP:0010788HP:0100005Testicular mesothelioma1WT1 CL E G H749083469ORPHA087312796607102
HP:0010788HP:0100616Testicular teratoma1WT1 CL E G H749083469ORPHA087312796607102
HP:0010788HP:0100618Leydig cell neoplasia1WT1 CL E G H749083469ORPHA087312796607102
HP:0010788HP:0025451Testicular adrenal rest tumor1WT1 CL E G H749083469ORPHA087312796607102
HP:0010788HP:0100617Testicular seminoma1WT1 CL E G H749083469ORPHA0101812796607102
HP:0010788HP:0100619Sertoli cell neoplasm1WT1 CL E G H749083469ORPHA0101812796607102
HP:0010788HP:0000030Testicular gonadoblastoma1WT1 CL E G H749083469ORPHA0101812796607102
HP:0010788HP:0008204Precocious puberty with Sertoli cell tumor2AKT1 CL E G H207744Aortic valves stenosis of the childORPHA0417391164730
HP:0010788HP:0008204Precocious puberty with Sertoli cell tumor2AKT1 CL E G H207744Aortic valves stenosis of the childORPHA0380391164730
HP:0010788HP:0008204Precocious puberty with Sertoli cell tumor2CDC73 CL E G H7957799880ORPHA082816783607393
HP:0010788HP:0008204Precocious puberty with Sertoli cell tumor2CDC73 CL E G H79577143ORPHA082816783607393
HP:0010788HP:0008204Precocious puberty with Sertoli cell tumor2CDC73 CL E G H7957799880ORPHA070416783607393
HP:0010788HP:0008204Precocious puberty with Sertoli cell tumor2CDC73 CL E G H79577143ORPHA070416783607393
HP:0010788HP:0008204Precocious puberty with Sertoli cell tumor2CDKN1B CL E G H1027276152ORPHA05071785600778
HP:0010788HP:0008204Precocious puberty with Sertoli cell tumor2CDKN1B CL E G H1027276152ORPHA05961785600778
HP:0010788HP:0008204Precocious puberty with Sertoli cell tumor2EWSR1 CL E G H213083469ORPHA0623508133450
HP:0010788HP:0008204Precocious puberty with Sertoli cell tumor2EWSR1 CL E G H213083469ORPHA0603508133450
HP:0010788HP:0008204Precocious puberty with Sertoli cell tumor2GNAS CL E G H2778562ORPHA03334392139320
HP:0010788HP:0008204Precocious puberty with Sertoli cell tumor2GNAS CL E G H2778562ORPHA03714392139320
HP:0010788HP:0008204Precocious puberty with Sertoli cell tumor2PTEN CL E G H5728744Aortic valves stenosis of the childORPHA022469588601728
HP:0010788HP:0008204Precocious puberty with Sertoli cell tumor2PTEN CL E G H5728744Aortic valves stenosis of the childORPHA024169588601728
HP:0010788HP:0008204Precocious puberty with Sertoli cell tumor2WT1 CL E G H749083469ORPHA087312796607102
HP:0010788HP:0008204Precocious puberty with Sertoli cell tumor2WT1 CL E G H749083469ORPHA0101812796607102


Genes (25) :AKT1 AR CDC73 CDKN1B DICER1 DMRT3 EWSR1 GATA4 GNAS H19 IGF2 KEAP1 MAP3K1 NR0B1 NR5A1 PRKAR1A PTEN SOX9 SRY STK11 STS VAMP7 WT1 WWOX ZFPM2

Diseases (13) :744 99880 143 276152 83469 562 99429 276399 251510 180860 1359 281090 175200
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.