Human Phenotype Ontology 
Grandparent Node:
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Localized skin lesion (HP:0011355)help
Parent Node:
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Hamartoma (HP:0010566)help
Parent Node:
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Nevus (HP:0003764)help
..Starting node
..expand
Numerous nevi (HP:0001054)help
Term ID: 1054
Name: Numerous nevi
Synonym: Multiple pigmented nevi; Numerous moles
Definition:
Comments:
Reference: HP:0001054
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAtypical nevi in non-sun exposed areas (HP:0001074) help
..expandAtypical nevus (HP:0001062) help
..expandBlue nevus (HP:0100814) help
..expandCongenital panfollicular nevus (HP:0025471) help
..expandConnective tissue nevi (HP:0100898) help
..expandEpidermal nevus (HP:0010816) help
..expandMelanocytic nevus (HP:0000995) help
..expandNevus flammeus (HP:0001052) help
..expandNevus of Ota (HP:0009920) help
..expandNevus sebaceus (HP:0025511) help
..expandNevus spilus (HP:0025510) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0001054HP:0001054Numerous nevi0BRAF CL E G H6731097OMIM:115150Cardiofaciocutaneous syndrome 1276
HP:0001054HP:0001054Numerous nevi0BRAF CL E G H6731097OMIM:613707Leopard syndrome 3276
HP:0001054HP:0001054Numerous nevi0BRAF CL E G H6731097OMIM:155600Melanoma, cutaneous malignant.276
HP:0001054HP:0001054Numerous nevi0BRAF CL E G H6731097OMIM:613706Noonan syndrome 7276
HP:0001054HP:0001054Numerous nevi0CDK4 CL E G H10191773OMIM:609048Melanoma, cutaneous malignant, susceptibility to, 3.145
HP:0001054HP:0001054Numerous nevi0FGFR3 CL E G H22613690OMIM:162900Epidermal nevus, somatic.145
HP:0001054HP:0001054Numerous nevi0HRAS CL E G H32655173OMIM:162900Epidermal nevus, somatic.113
HP:0001054HP:0001054Numerous nevi0KANSL1 CL E G H28405824565ORPHA:36395817q21.31 microdeletion syndromeHP:0040283 - Occasional283
HP:0001054HP:0001054Numerous nevi0KANSL1 CL E G H28405824565ORPHA:363965Koolen-De Vries syndrome due to a point mutationHP:0040283 - Occasional283
HP:0001054HP:0001054Numerous nevi0NRAS CL E G H48937989OMIM:162900Epidermal nevus, somatic.102
HP:0001054HP:0001054Numerous nevi0PCGF2 CL E G H770312929OMIM:618371Turnpenny-Fry syndrome.
HP:0001054HP:0001054Numerous nevi0PIK3CA CL E G H52908975OMIM:162900Epidermal nevus, somatic.162
HP:0001054HP:0001054Numerous nevi0STK11 CL E G H679411389OMIM:155600Melanoma, cutaneous malignant.740


Genes (9) :BRAF CDK4 FGFR3 HRAS KANSL1 NRAS PCGF2 PIK3CA STK11

Diseases (9) :OMIM:115150 OMIM:613707 OMIM:155600 OMIM:613706 OMIM:609048 OMIM:162900 ORPHA:363958 ORPHA:363965 OMIM:618371
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.