Human Phenotype Ontology 
Grandparent Node:
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Inflammatory abnormality of the skin (HP:0011123)help
Parent Node:
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Eczema (HP:0000964)help
..Starting node
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Seborrheic dermatitis (HP:0001051)help
Term ID: 1051
Name: Seborrheic dermatitis
Synonym: Dysseborrheic dermatitis; Seborrhea; Seborrheic eczema
Definition: Seborrheic dermatitis is a form of eczema which is closely related to dandruff. It causes dry or greasy peeling of the scalp, eyebrows, and face, and sometimes trunk.
Comments:
Reference: HP:0001051
Genes and Diseases:
 
       Child Nodes:
........expandGeneralized seborrheic dermatitis (HP:0007569) help

 Sister Nodes: 
..expandEczematoid dermatitis (HP:0000976) help
..expandPerioral eczema (HP:0011127) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0001051HP:0001051Seborrheic dermatitis0ARVCF CL E G H421728ORPHA:56722q11.2 deletion syndromeHP:0040282 - Frequent1
HP:0001051HP:0001051Seborrheic dermatitis0BTD CL E G H6861122OMIM:253260Biotinidase deficiencymultiple carboxylase deficiency, late-onset.223
HP:0001051HP:0001051Seborrheic dermatitis0C5 CL E G H7271331OMIM:609536C5 deficiency16
HP:0001051HP:0001051Seborrheic dermatitis0CARMIL2 CL E G H14620627089OMIM:618131IMMUNODEFICIENCY 58; IMD583
HP:0001051HP:0001051Seborrheic dermatitis0CIB1 CL E G H1051916920ORPHA:302Epidermodysplasia verruciformisHP:0040281 - Very frequent
HP:0001051HP:0001051Seborrheic dermatitis0COMT CL E G H13122228ORPHA:56722q11.2 deletion syndromeHP:0040282 - Frequent6
HP:0001051HP:0001051Seborrheic dermatitis0GP1BB CL E G H28124440ORPHA:56722q11.2 deletion syndromeHP:0040282 - Frequent8
HP:0001051HP:0001051Seborrheic dermatitis0HIRA CL E G H72904916ORPHA:56722q11.2 deletion syndromeHP:0040282 - Frequent3
HP:0001051HP:0001051Seborrheic dermatitis0HPGD CL E G H32485154OMIM:259100Hypertrophic osteoarthropathy, primary, autosomal recessive 1.55
HP:0001051HP:0001051Seborrheic dermatitis0HPGD CL E G H32485154ORPHA:2796PachydermoperiostosisHP:0040281 - Very frequent55
HP:0001051HP:0001051Seborrheic dermatitis0IL7 CL E G H35746023ORPHA:302Epidermodysplasia verruciformisHP:0040281 - Very frequent
HP:0001051HP:0001051Seborrheic dermatitis0JMJD1C CL E G H22103712313ORPHA:56722q11.2 deletion syndromeHP:0040282 - Frequent2
HP:0001051HP:0001051Seborrheic dermatitis0MCCC2 CL E G H640876937OMIM:2102103-Methylcrotonyl-CoA carboxylase 2 deficiency.77
HP:0001051HP:0001051Seborrheic dermatitis0PIGA CL E G H52778957OMIM:300868Multiple congenital anomalies-hypotonia-seizures syndrome 2HP:0040283 - Occasional46
HP:0001051HP:0001051Seborrheic dermatitis0PIGA CL E G H52778957OMIM:301072NEURODEVELOPMENTAL DISORDER WITH EPILEPSY AND HEMOCHROMATOSIS; NEDEPH46
HP:0001051HP:0001051Seborrheic dermatitis0PIK3CA CL E G H52908975ORPHA:276280Hemihyperplasia-multiple lipomatosis syndromeHP:0040283 - Occasional162
HP:0001051HP:0001051Seborrheic dermatitis0RBM8A CL E G H99399905OMIM:274000Thrombocytopenia-absent radius syndrome.10
HP:0001051HP:0001051Seborrheic dermatitis0RREB1 CL E G H623910449ORPHA:56722q11.2 deletion syndromeHP:0040282 - Frequent
HP:0001051HP:0001051Seborrheic dermatitis0SEC24C CL E G H963210705ORPHA:56722q11.2 deletion syndromeHP:0040282 - Frequent
HP:0001051HP:0001051Seborrheic dermatitis0SLC39A7 CL E G H79224927OMIM:619693AGAMMAGLOBULINEMIA 9, AUTOSOMAL RECESSIVE; AGM9
HP:0001051HP:0001051Seborrheic dermatitis0SLCO2A1 CL E G H657810955OMIM:167100Hypertrophic osteoarthropathy, primary, autosomal dominant13
HP:0001051HP:0001051Seborrheic dermatitis0SLCO2A1 CL E G H657810955OMIM:614441Hypertrophic osteoarthropathy, primary, autosomal recessive 213
HP:0001051HP:0001051Seborrheic dermatitis0SLCO2A1 CL E G H657810955ORPHA:2796PachydermoperiostosisHP:0040281 - Very frequent13
HP:0001051HP:0001051Seborrheic dermatitis0TBX1 CL E G H689911592ORPHA:56722q11.2 deletion syndromeHP:0040282 - Frequent32
HP:0001051HP:0001051Seborrheic dermatitis0TBX1 CL E G H689911592OMIM:188400Digeorge syndrome.32
HP:0001051HP:0001051Seborrheic dermatitis0TKT CL E G H708611834ORPHA:488618Transketolase deficiencyHP:0040283 - Occasional4
HP:0001051HP:0001051Seborrheic dermatitis0TMC6 CL E G H1132218021ORPHA:302Epidermodysplasia verruciformisHP:0040281 - Very frequent10
HP:0001051HP:0001051Seborrheic dermatitis0TMC8 CL E G H14713820474ORPHA:302Epidermodysplasia verruciformisHP:0040281 - Very frequent4
HP:0001051HP:0001051Seborrheic dermatitis0TRAF3IP2 CL E G H107581343OMIM:615527Candidiasis, familial, 8.4
HP:0001051HP:0001051Seborrheic dermatitis0UFD1 CL E G H735312520ORPHA:56722q11.2 deletion syndromeHP:0040282 - Frequent
HP:0001051HP:0001051Seborrheic dermatitis0ZNF750 CL E G H7975525843OMIM:610227Seborrhea-Like dermatitis with psoriasiform elements.2
HP:0001051HP:0007569Generalized seborrheic dermatitis1C5 CL E G H7271331OMIM:609536C5 deficiency.16


Genes (26) :ARVCF BTD C5 CARMIL2 CIB1 COMT GP1BB HIRA HPGD IL7 JMJD1C MCCC2 PIGA PIK3CA RBM8A RREB1 SEC24C SLC39A7 SLCO2A1 TBX1 TKT TMC6 TMC8 TRAF3IP2 UFD1 ZNF750

Diseases (19) :ORPHA:567 OMIM:253260 OMIM:609536 OMIM:618131 ORPHA:302 OMIM:259100 ORPHA:2796 OMIM:210210 OMIM:300868 OMIM:301072 ORPHA:276280 OMIM:274000 OMIM:619693 OMIM:167100 OMIM:614441 OMIM:188400 ORPHA:488618 OMIM:615527 OMIM:610227
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.