MSeqDR Mitochondrial disease browser phenotype pathogenic gene and mutation portal

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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

MSeqDR Mitochondrial Disease Portal

*:HP: HPO terms, UMDF: 1= Disease, ND: NAMDC terms.
Most Studied CPEO, Complex I Deficiency, COXPD1, Leigh, LHON, MELAS, MERRF, Myopathy, SANDO

Disease Browser
Parent Node: Adenomatous Polyps (D018256)
Parent Node: Colorectal Neoplasms (D015179)
Parent Node: Intestinal Polyposis (D044483)
Parent Node: Neoplastic Syndromes, Hereditary (D009386)
..Starting node ..Adenomatous Polyposis Coli (D011125)
Child Nodes:
........Attenuated familial adenomatous polyposis (C538265)
........Colorectal Adenomatous Polyposis, Autosomal Recessive (C563924)
........Desmoid disease, hereditary (C535944)
........Gardner Syndrome (D005736) 3
........Leukemia, Acute Myelocytic, with Polyposis Coli and Colon Cancer (C565441)
........Polyposis Syndrome, Hereditary Mixed, 1 (C563365)
........Polyposis Syndrome, Hereditary Mixed, 2 (C566451)
Sister Nodes:
..Adenomatous Polyposis Coli (D011125) 10
..Basal Cell Nevus Syndrome (D001478) 1
..Birt-Hogg-Dube Syndrome (D058249)
..Cancer, Familial, with In Vitro Radioresistance (C566179)
..Collagenoma, Familial Cutaneous (C562925)
..Colorectal Neoplasms, Hereditary Nonpolyposis (D003123) 10
..Diaphyseal medullary stenosis with malignant fibrous histiocytoma (C536169)
..Dysplastic Nevus Syndrome (D004416)
..Exostoses, Multiple Hereditary (D005097) 14
..Familial cylindromatosis (C536611)
..Genochondromatosis (C563215)
..Hamartoma Syndrome, Multiple (D006223) 10
..Hemangioma, capillary infantile (C535860)
..Hereditary Breast and Ovarian Cancer Syndrome (D061325)
..Hereditary leiomyomatosis and renal cell cancer (C535516)
..Juvenile polyposis syndrome (C537702)
..Li-Fraumeni Syndrome (D016864) 4
..Melanoma-Pancreatic Cancer Syndrome (C563985)
..Meningioma, familial (C537443)
..Multiple Endocrine Neoplasia (D009377) 6
..Myelocytic leukemia-like syndrome, familial, chronic (C536093)
..Neurofibromatoses (D017253) 13 C:1
..Paragangliomas 2 (C566646)
..Paragangliomas 3 (C565335)
..Peutz-Jeghers Syndrome (D010580)
..Prostate Cancer, Hereditary, 12 (C567510)
..Tuberous Sclerosis (D014402) 4
..Turcot syndrome (C536928)
..Wilms Tumor (D009396) 10
Human Disease MESH is developed by UMLS. Further data from MedGen, OMIM,ClinVar, CTD

Term ID:

300

Name:

Adenomatous Polyposis Coli

Definition:

A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.

Alternative IDs:

DO:DOID:0050424|OMIM:175100|OMIM:616415|OMIM:617100

ParentIDs:

MESH:D009386|MESH:D015179|MESH:D018256|MESH:D044483

TreeNumbers:

C04.557.470.035.215.100 |C04.588.274.476.411.307.089 |C04.700.100 |C06.301.371.411.307.090 |C06.405.249.411.307.090 |C06.405.469.158.356.090 |C06.405.469.491.307.090 |C06.405.469.578.249 |C16.320.700.100

Synonyms:

Slim Mappings:

Cancer|Digestive system disease|Genetic disease (inborn)

Reference:

MedGen: D011125
MeSH: D011125
OMIM: 175100;
MSeqDR :
Genes: APC; PKLR;

Phenotypes

1	HP:0000006	Autosomal dominant inheritance
2	HP:0005227	Adenomatous colonic polyposis	HP:0040281
3	HP:0008256	Adrenocortical adenoma	HP:0040284
4	HP:0006744	Adrenocortical carcinoma
5	HP:0009592	Astrocytoma
6	HP:0000670	Carious teeth	HP:0040283
7	HP:0003003	Colon cancer	HP:0040282
8	HP:0007649	Congenital hypertrophy of retinal pigment epithelium	HP:0040283
9	HP:0100245	Desmoid tumors	HP:0040284
10	HP:0006771	Duodenal adenocarcinoma	HP:0040284
11	HP:0004783	Duodenal polyposis	HP:0040284
12	HP:0200040	Epidermoid cyst	HP:0040283
13	HP:0010619	Fibroadenoma of the breast	HP:0040283
14	HP:0002884	Hepatoblastoma	HP:0040284
15	HP:0000953	Hyperpigmentation of the skin
16	HP:0011069	Increased number of teeth	HP:0040283
17	HP:0010562	Keloids
18	HP:0002885	Medulloblastoma	HP:0040284
19	HP:0004394	Multiple gastric polyps	HP:0040282
20	HP:0001012	Multiple lipomas
21	HP:0011068	Odontoma
22	HP:0100246	Osteoma	HP:0040283
23	HP:0002895	Papillary thyroid carcinoma	HP:0040284
24	HP:0006722	Small intestine carcinoid
25	HP:0000706	Unerupted tooth	HP:0040283
26	HP:0003828	Variable expressivity

Disease Causing ClinVar Variants

Variation_Name	GeneID	GeneSymbol	ClinicalSignificance	dbSNP	RCVaccession	TestedInGTR	PhenotypeIDs	Chromosome	Start	Stop	HGVS_c	HGVS_p	HGVS_g	OtherIDs	Disease_ClinVar
NC_000005.9:g.112001178_112043328del42151	324	APC	Likely pathogenic	-1	RCV000704595;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112001178	112043328	na	na		-	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.(?_112001178)_(112043328_?)del	324	APC	Pathogenic	-1	RCV001920059;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112001178	112043328	na	na	-1	-
NC_000005.9:g.112043006_112043009delinsCCCA	324	APC	Uncertain significance	-1	RCV002015123;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043006	112043009	GGGC	CCCA	112043006	-
NC_000005.10:g.(?_112707312)_(112707902_?)del	324	APC	Pathogenic	-1	RCV000493148\|RCV001865533;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043009	112043599	na	na		-	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.(?_112043009)_(112043599_?)dup	324	APC	Uncertain significance	-1	RCV000557176\|RCV001853708;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043009	112043599	na	na		-	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.10:g.(?_112707312)_(112780909_?)del	324	APC	Pathogenic	-1	RCV000535350\|RCV001853709;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043009	112116606	na	na	-1	-
NM_000038.5(APC):c.-30632C>T	324	APC	Benign	rs185951958	RCV000534603;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043009	112043009	C	T	NC_000005.9:g.112043009C>T	ClinGen:CA124924532	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.(?_112043009)_(112073585_?)dup	324	APC	Uncertain significance	-1	RCV000808623\|RCV001856253;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043009	112073585	na	na		-
NC_000005.10:g.(?_112707312)_(112780913_?)del	324	APC	Pathogenic	-1	RCV000802583\|RCV001856249;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043009	112116610	na	na		-
NC_000005.10:g.(?_112707312)_(112844136_?)del	324	APC	Pathogenic	-1	RCV000813324\|RCV001869256;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043009	112179833	na	na		-
NC_000005.9:g.(?_112043009)_(112111444_?)dup	324	APC	Uncertain significance	-1	RCV000821942;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043009	112111444	na	na		-
NC_000005.10:g.(?_112707312)_(112844126_?)del	324	APC	Pathogenic	-1	RCV000820596\|RCV001856258;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043009	112179823	na	na		-
NC_000005.10:g.(?_112707312)_(112755035_?)del	324	APC	Pathogenic	-1	RCV001032582;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043009	112090732	na	na	-1	-
NC_000005.10:g.(?_112707312)_(112779851_?)dup	324	APC	Uncertain significance	-1	RCV001032224\|RCV001862449;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043009	112115548	na	na	-1	-
NC_000005.10:g.(?_112707312)_(112828982_?)dup	324	APC	Uncertain significance	-1	RCV001031303\|RCV001862443;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043009	112164679	na	na	-1	-
NC_000005.10:g.(?_112707312)_(112844136_?)dup	324	APC	Uncertain significance	-1	RCV001032102;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043009	112179833	na	na	-1	-
NC_000005.9:g.112043009_112043010insTGCA	324	APC	Uncertain significance	-1	RCV001368938;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043009	112043010	C	CTGCA	112043009	-
NC_000005.9:g.(?_112043009)_(112151296_?)del	324	APC	Pathogenic	-1	RCV001381156;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043009	112151296	na	na	-1	-
NC_000005.9:g.(?_112043009)_(112182936_?)del	324	APC	Pathogenic	-1	RCV001381152;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043009	112182936	na	na	-1	-
NC_000005.9:g.(?_112043009)_(112073585_?)del	324	APC	Pathogenic	-1	RCV001953897;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043009	112073585	na	na	-1	-
NC_000005.9:g.(?_112043009)_(112103097_?)del	324	APC	Pathogenic	-1	RCV001953492;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043009	112103097	na	na	-1	-
NC_000005.9:g.(?_112043009)_(112179829_?)del	324	APC	Pathogenic	-1	RCV001949513;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043009	112179829	na	na	-1	-
NM_000038.6(APC):c.-30630G>A	324	APC	Uncertain significance	rs1214142280	RCV000803445;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043011	112043011	G	A	5:g.112043011G>A	-
NC_000005.9:g.112043012C>T	324	APC	Uncertain significance	rs1750548089	RCV001297737;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043012	112043012	C	T	112043012	-
NC_000005.9:g.112043013A>G	324	APC	Uncertain significance	-1	RCV002010155;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043013	112043013	A	G	112043013	-
NC_000005.9:g.112043013A>T	324	APC	Uncertain significance	-1	RCV001940042;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043013	112043013	A	T	112043013	-
NC_000005.9:g.112043014G>C	324	APC	Uncertain significance	-1	RCV001870634;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043014	112043014	G	C	112043014	-
NM_000038.5(APC):c.-30626C>G	324	APC	Uncertain significance	rs931897682	RCV000558548;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043015	112043015	C	G	5:g.112043015C>G	ClinGen:CA124924533	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043017C>A	324	APC	Uncertain significance	-1	RCV001965565;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043017	112043017	C	A	112043017	-
NC_000005.9:g.112043020T>C	324	APC	Uncertain significance	-1	RCV001363041;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043020	112043020	T	C	112043020	-
NC_000005.9:g.112043022C>G	324	APC	Uncertain significance	rs1750548351	RCV001351971;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043022	112043022	C	G	112043022	-
NC_000005.9:g.112043023_112043024insGAGAAGGCCAGTAAGTGCTGCAACT	324	APC	Uncertain significance	-1	RCV001373802;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043023	112043024	A	AGAGAAGGCCAGTAAGTGCTGCAACT	112043023	-
NC_000005.9:g.112043023A>T	324	APC	Uncertain significance	-1	RCV001890049;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043023	112043023	A	T	112043023	-
NC_000005.9:g.112043024G>C	324	APC	Uncertain significance	rs1750548429	RCV001320857;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043024	112043024	G	C	112043024	-
NC_000005.9:g.112043025_112043027del	324	APC	Uncertain significance	-1	RCV002037106;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043025	112043027	GAGA	G	112043024	-
NC_000005.9:g.112043026G>A	324	APC	Uncertain significance	rs1750548760	RCV001325712;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043026	112043026	G	A	112043026	-
NM_000038.6(APC):c.-30612G>A	324	APC	Uncertain significance	rs1461935725	RCV000799564;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043029	112043029	G	A	5:g.112043029G>A	-
NM_000038.6(APC):c.-30612G>C	324	APC	Uncertain significance	rs1461935725	RCV000804953;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043029	112043029	G	C	5:g.112043029G>C	-
NC_000005.9:g.112043029del	324	APC	Uncertain significance	-1	RCV001360440;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043029	112043029	AG	A	112043028	-
NM_000038.5(APC):c.-30611G>T	324	APC	Uncertain significance	rs1554060090	RCV000646547;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043030	112043030	G	T	5:g.112043030G>T	ClinGen:CA658796584	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.-30611G>A	324	APC	Uncertain significance	rs1554060090	RCV000792135;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043030	112043030	G	A	5:g.112043030G>A	-
NM_000038.5(APC):c.-30610C>T	324	APC	Uncertain significance	rs1554060091	RCV000546163;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043031	112043031	C	T	NC_000005.9:g.112043031C>T	ClinGen:CA658655864	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30608A>G	324	APC	Uncertain significance	rs1554060092	RCV000545228;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043033	112043033	A	G	5:g.112043033A>G	ClinGen:CA658655865	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30608A>T	324	APC	Uncertain significance	rs1554060092	RCV000557633;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043033	112043033	A	T	5:g.112043033A>T	ClinGen:CA658655866	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.-30608dup	324	APC	Uncertain significance	rs1293984809	RCV000807321;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043033	112043033	C	CA	5:g.112043032_112043033insA	-
NC_000005.9:g.112043034G>A	324	APC	Uncertain significance	-1	RCV002044864;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043034	112043034	G	A	112043034	-
NM_000038.6(APC):c.-30606dup	324	APC	Uncertain significance	rs1156546602	RCV000800720;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043035	112043035	G	GT	5:g.112043034_112043035insT	-
NC_000005.9:g.112043035T>C	324	APC	Uncertain significance	rs1750549577	RCV001346044;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043035	112043035	T	C	112043035	-
NM_000038.5(APC):c.-30605A>T	324	APC	Uncertain significance	rs1554060095	RCV000532741;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043036	112043036	A	T	NC_000005.9:g.112043036A>T	ClinGen:CA445747779	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043036A>G	324	APC	Uncertain significance	rs1554060095	RCV001295133;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043036	112043036	A	G	112043036	-
NC_000005.9:g.112043037A>G	324	APC	Uncertain significance	rs1469439532	RCV001308881;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043037	112043037	A	G	112043037	-
NM_000038.5(APC):c.-30603G>C	324	APC	Uncertain significance	rs1554060097	RCV000646528;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043038	112043038	G	C	NC_000005.9:g.112043038G>C	ClinGen:CA658796585	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.-30602T>C	324	APC	Uncertain significance	rs1580995288	RCV000802426;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043039	112043039	T	C	5:g.112043039T>C	-
NC_000005.9:g.112043039T>G	324	APC	Uncertain significance	rs1580995288	RCV001316399;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043039	112043039	T	G	112043039	-
NM_000038.6(APC):c.-30601G>C	324	APC	Uncertain significance	rs1050218356	RCV000822079;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043040	112043040	G	C	5:g.112043040G>C	-
NC_000005.9:g.112043041C>G	324	APC	Uncertain significance	-1	RCV001372664;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043041	112043041	C	G	112043041	-
NC_000005.9:g.112043042del	324	APC	Uncertain significance	rs1750550359	RCV001313067;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043042	112043042	CT	C	112043041	-
NC_000005.9:g.112043042T>C	324	APC	Uncertain significance	rs1750550286	RCV001321554;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043042	112043042	T	C	112043042	-
NM_000038.6(APC):c.-30598G>A	324	APC	Uncertain significance	rs1232455560	RCV000792123;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043043	112043043	G	A	5:g.112043043G>A	-
NC_000005.9:g.112043043G>C	324	APC	Uncertain significance	rs1232455560	RCV001344582;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043043	112043043	G	C	112043043	-
NC_000005.9:g.112043043G>T	324	APC	Uncertain significance	-1	RCV002049823;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043043	112043043	G	T	112043043	-
NM_000038.6(APC):c.-30596A>G	324	APC	Uncertain significance	rs887610659	RCV000816471;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043045	112043045	A	G	5:g.112043045A>G	-
NC_000005.9:g.112043045A>C	324	APC	Uncertain significance	-1	RCV001973815;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043045	112043045	A	C	112043045	-
NC_000005.9:g.112043046A>G	324	APC	Uncertain significance	rs1750550706	RCV001348074;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043046	112043046	A	G	112043046	-
NC_000005.9:g.112043047C>T	324	APC	Uncertain significance	rs1750550790	RCV001299893;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043047	112043047	C	T	112043047	-
NC_000005.9:g.112043047C>A	324	APC	Uncertain significance	rs1750550790	RCV001320223;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043047	112043047	C	A	112043047	-
NM_000038.5(APC):c.-30593T>C	324	APC	Uncertain significance	rs1554060105	RCV000556687;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043048	112043048	T	C	NC_000005.9:g.112043048T>C	ClinGen:CA658655867	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043049G>T	324	APC	Uncertain significance	-1	RCV002021578;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043049	112043049	G	T	112043049	-
NM_000038.6(APC):c.-30591dup	324	APC	Uncertain significance	rs1580995299	RCV000808111;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043050	112043050	G	GA	5:g.112043049_112043050insA	-
NM_000038.5(APC):c.-30590G>A	324	APC	Likely benign	rs545524187	RCV000544296;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043051	112043051	G	A	NC_000005.9:g.112043051G>A	ClinGen:CA124924542	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043051G>C	324	APC	Uncertain significance	rs545524187	RCV001337730;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043051	112043051	G	C	112043051	-
NC_000005.9:g.112043052A>G	324	APC	Uncertain significance	rs1750551409	RCV001326226;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043052	112043052	A	G	112043052	-
NC_000005.9:g.112043052A>T	324	APC	Uncertain significance	-1	RCV002024325;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043052	112043052	A	T	112043052	-
NC_000005.9:g.112043053C>T	324	APC	Uncertain significance	-1	RCV001996528;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043053	112043053	C	T	112043053	-
NM_000038.6(APC):c.-30587T>A	324	APC	Uncertain significance	rs1580995308	RCV000795331;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043054	112043054	T	A	5:g.112043054T>A	-
NM_000038.5(APC):c.-30586C>T	324	APC	Uncertain significance	rs1554060110	RCV000646677;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043055	112043055	C	T	5:g.112043055C>T	ClinGen:CA658796586	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30585G>T	324	APC	Uncertain significance	rs560366894	RCV000646645;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043056	112043056	G	T	NC_000005.9:g.112043056G>T	ClinGen:CA658796587	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.-30585G>C	324	APC	Uncertain significance	rs560366894	RCV000809131;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043056	112043056	G	C	5:g.112043056G>C	-
NC_000005.9:g.112043058_112043059delinsTG	324	APC	Uncertain significance	rs1750551900	RCV001299737;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043058	112043059	CT	TG	112043058	-
NC_000005.9:g.112043058C>A	324	APC	Uncertain significance	rs1750551783	RCV001337518;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043058	112043058	C	A	112043058	-
NC_000005.9:g.112043058C>G	324	APC	Uncertain significance	rs1750551783	RCV001339615;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043058	112043058	C	G	112043058	-
NC_000005.9:g.112043058_112043059delinsGG	324	APC	Uncertain significance	-1	RCV001366310;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043058	112043059	CT	GG	112043058	-
NC_000005.9:g.112043059T>C	324	APC	Uncertain significance	rs113077479	RCV001319338;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043059	112043059	T	C	112043059	-
NC_000005.9:g.112043059T>G	324	APC	Uncertain significance	-1	RCV001363097;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043059	112043059	T	G	112043059	-
NC_000005.9:g.112043059T>A	324	APC	Uncertain significance	-1	RCV001982790;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043059	112043059	T	A	112043059	-
NM_000038.6(APC):c.-30581G>A	324	APC	Uncertain significance	rs1580995331	RCV000816264;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043060	112043060	G	A	5:g.112043060G>A	-
NC_000005.9:g.112043060_112043061delinsCT	324	APC	Uncertain significance	-1	RCV002006158;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043060	112043061	GC	CT	112043060	-
NC_000005.9:g.112043061C>T	324	APC	Uncertain significance	-1	RCV001995086;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043061	112043061	C	T	112043061	-
NC_000005.9:g.112043061C>A	324	APC	Uncertain significance	-1	RCV001995137;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043061	112043061	C	A	112043061	-
NM_000038.5(APC):c.-30579C>T	324	APC	Uncertain significance	rs1554060114	RCV000531822;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043062	112043062	C	T	5:g.112043062C>T	ClinGen:CA658655868	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30578T>C	324	APC	Uncertain significance	rs929883108	RCV000555784;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043063	112043063	T	C	NC_000005.9:g.112043063T>C	ClinGen:CA124924550	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043063T>G	324	APC	Uncertain significance	-1	RCV002028198;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043063	112043063	T	G	112043063	-
NM_000038.5(APC):c.-30577A>G	324	APC	Uncertain significance	rs1046974767	RCV000538765;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043064	112043064	A	G	NC_000005.9:g.112043064A>G	ClinGen:CA124924554	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043064A>C	324	APC	Uncertain significance	-1	RCV001361106;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043064	112043064	A	C	112043064	-
NM_000038.5(APC):c.-30576G>A	324	APC	Uncertain significance	rs1320184514	RCV000646536;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043065	112043065	G	A	NC_000005.9:g.112043065G>A	ClinGen:CA658796588	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043065G>T	324	APC	Uncertain significance	rs1320184514	RCV001320965;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043065	112043065	G	T	112043065	-
NM_000038.6(APC):c.-30575G>A	324	APC	Uncertain significance	rs1232017569	RCV000801035;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043066	112043066	G	A	5:g.112043066G>A	-
NM_000038.5(APC):c.-30574C>T	324	APC	Uncertain significance	rs1273083857	RCV000530895;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043067	112043067	C	T	5:g.112043067C>T	ClinGen:CA561890078	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043067C>A	324	APC	Uncertain significance	-1	RCV001366214;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043067	112043067	C	A	112043067	-
NC_000005.9:g.112043067C>G	324	APC	Uncertain significance	-1	RCV001902548;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043067	112043067	C	G	112043067	-
NM_000038.5(APC):c.-30573A>G	324	APC	Uncertain significance	rs1554060123	RCV000554842;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043068	112043068	A	G	NC_000005.9:g.112043068A>G	ClinGen:CA658655869	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043069_112043070delinsTT	324	APC	Uncertain significance	rs1750552770	RCV001348652;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043069	112043070	GC	TT	112043069	-
NC_000005.9:g.112043071A>C	324	APC	Uncertain significance	-1	RCV001894939;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043071	112043071	A	C	112043071	-
NM_000038.5(APC):c.-30569A>G	324	APC	Benign	rs13180781	RCV000421417\|RCV000542411;	N	MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043072	112043072	A	G	5:g.112043072A>G	ClinGen:CA12147799	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043072_112043073delinsGC	324	APC	Uncertain significance	rs1750553249	RCV001338537;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043072	112043073	AT	GC	112043072	-
NC_000005.9:g.112043072A>C	324	APC	Uncertain significance	-1	RCV001362678;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043072	112043072	A	C	112043072	-
NM_000038.5(APC):c.-30568T>C	324	APC	Benign	rs1218378018	RCV000525417;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043073	112043073	T	C	5:g.112043073T>C	ClinGen:CA561890079	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043073T>G	324	APC	Uncertain significance	rs1218378018	RCV001317758;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043073	112043073	T	G	112043073	-
NC_000005.9:g.112043074G>A	324	APC	Uncertain significance	rs1005173527	RCV001341712;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043074	112043074	G	A	112043074	-
NM_000038.6(APC):c.-30566G>C	324	APC	Uncertain significance	rs1243549213	RCV000812467;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043075	112043075	G	C	5:g.112043075G>C	-
NC_000005.9:g.112043075G>A	324	APC	Uncertain significance	rs1243549213	RCV001301751;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043075	112043075	G	A	112043075	-
NC_000005.9:g.112043075G>T	324	APC	Uncertain significance	-1	RCV001972156;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043075	112043075	G	T	112043075	-
NC_000005.9:g.112043076C>G	324	APC	Uncertain significance	-1	RCV001374205;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043076	112043076	C	G	112043076	-
NC_000005.9:g.112043078C>G	324	APC	Uncertain significance	-1	RCV001995903;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043078	112043078	C	G	112043078	-
NC_000005.9:g.112043079A>T	324	APC	Uncertain significance	-1	RCV001986911;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043079	112043079	A	T	112043079	-
NC_000005.9:g.112043080C>G	324	APC	Uncertain significance	rs1484697641	RCV001344735;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043080	112043080	C	G	112043080	-
NM_000038.5(APC):c.-30560G>A	324	APC	Uncertain significance	rs1554060128	RCV000541490;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043081	112043081	G	A	5:g.112043081G>A	ClinGen:CA658655870	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30560G>C	324	APC	Uncertain significance	rs1554060128	RCV000549428;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043081	112043081	G	C	NC_000005.9:g.112043081G>C	ClinGen:CA658655871	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30559G>C	324	APC	Likely benign	rs1192399402	RCV000529027;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043082	112043082	G	C	NC_000005.9:g.112043082G>C	ClinGen:CA561890086	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043082G>A	324	APC	Uncertain significance	rs1192399402	RCV001322826;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043082	112043082	G	A	112043082	-
NM_000038.5(APC):c.-30558G>C	324	APC	Uncertain significance	rs1351477360	RCV000548472;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043083	112043083	G	C	NC_000005.9:g.112043083G>C	ClinGen:CA658655872	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043083G>A	324	APC	Uncertain significance	-1	RCV001966471;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043083	112043083	G	A	112043083	-
NM_000038.5(APC):c.-30555A>C	324	APC	Benign	rs1257642100	RCV000535990;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043086	112043086	A	C	5:g.112043086A>C	ClinGen:CA561890088	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043086_112043087del	324	APC	Uncertain significance	rs1316145446	RCV001300615;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043086	112043087	CAG	C	112043085	-
NC_000005.9:g.112043086A>G	324	APC	Uncertain significance	-1	RCV002005136;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043086	112043086	A	G	112043086	-
NC_000005.9:g.112043087G>C	324	APC	Uncertain significance	rs1750554761	RCV001303797;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043087	112043087	G	C	112043087	-
NC_000005.9:g.112043087G>T	324	APC	Uncertain significance	-1	RCV002037612;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043087	112043087	G	T	112043087	-
NC_000005.9:g.112043088A>G	324	APC	Uncertain significance	-1	RCV001371623;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043088	112043088	A	G	112043088	-
NC_000005.9:g.112043088A>T	324	APC	Uncertain significance	-1	RCV001963696;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043088	112043088	A	T	112043088	-
NM_000038.5(APC):c.-30551C>G	324	APC	Uncertain significance	rs994601309	RCV000559955;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043090	112043090	C	G	5:g.112043090C>G	ClinGen:CA124924605	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043090C>T	324	APC	Uncertain significance	-1	RCV001929626;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043090	112043090	C	T	112043090	-
NM_000038.5(APC):c.-30550A>G	324	APC	Uncertain significance	rs571137741	RCV000646684;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043091	112043091	A	G	5:g.112043091A>G	ClinGen:CA124924620	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043093C>T	324	APC	Uncertain significance	-1	RCV001362529;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043093	112043093	C	T	112043093	-
NM_000038.5(APC):c.-30547G>T	324	APC	Uncertain significance	rs1554060134	RCV000646618;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043094	112043094	G	T	NC_000005.9:g.112043094G>T	ClinGen:CA658796589	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043094G>A	324	APC	Uncertain significance	rs1554060134	RCV001327854;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043094	112043094	G	A	112043094	-
NC_000005.9:g.112043095A>C	324	APC	Uncertain significance	-1	RCV002048899;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043095	112043095	A	C	112043095	-
NC_000005.9:g.112043095del	324	APC	Uncertain significance	-1	RCV002001446;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043095	112043095	GA	G	112043094	-
NM_000038.6(APC):c.-30545A>G	324	APC	Uncertain significance	rs1580995476	RCV000811852;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043096	112043096	A	G	5:g.112043096A>G	-
NC_000005.9:g.112043096_112043097insGCAGTGCCCGGCAAGCGGAGC	324	APC	Uncertain significance	-1	RCV001934246;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043096	112043097	A	AGCAGTGCCCGGCAAGCGGAGC	112043096	-
NC_000005.9:g.112043097G>A	324	APC	Uncertain significance	rs1750555732	RCV001294660;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043097	112043097	G	A	112043097	-
NC_000005.9:g.112043097_112043098insCAGT	324	APC	Uncertain significance	-1	RCV001366274;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043097	112043098	G	GCAGT	112043097	-
NC_000005.9:g.112043097G>C	324	APC	Uncertain significance	-1	RCV001891530;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043097	112043097	G	C	112043097	-
NM_000038.5(APC):c.-30543C>G	324	APC	Uncertain significance	rs1554060135	RCV000646635;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043098	112043098	C	G	NC_000005.9:g.112043098C>G	ClinGen:CA658796590	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043099A>G	324	APC	Uncertain significance	-1	RCV001373872;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043099	112043099	A	G	112043099	-
NC_000005.9:g.112043099A>C	324	APC	Uncertain significance	-1	RCV002008391;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043099	112043099	A	C	112043099	-
NM_000038.5(APC):c.-30541G>C	324	APC	Uncertain significance	rs1035047381	RCV000547630;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043100	112043100	G	C	5:g.112043100G>C	ClinGen:CA124924622	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.-30541G>A	324	APC	Uncertain significance	rs1035047381	RCV000802886;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043100	112043100	G	A	5:g.112043100G>A	-
NM_000038.5(APC):c.-30540T>C	324	APC	Uncertain significance	rs1248905809	RCV000646580;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043101	112043101	T	C	5:g.112043101T>C	ClinGen:CA658796592	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30540T>A	324	APC	Uncertain significance	rs1248905809	RCV000646617;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043101	112043101	T	A	NC_000005.9:g.112043101T>A	ClinGen:CA658796591	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043102G>A	324	APC	Uncertain significance	rs1580995493	RCV001314676;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043102	112043102	G	A	112043102	-
NC_000005.9:g.112043102G>C	324	APC	Uncertain significance	-1	RCV001916774;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043102	112043102	G	C	112043102	-
NC_000005.9:g.112043103C>A	324	APC	Uncertain significance	rs1750556409	RCV001308858;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043103	112043103	C	A	112043103	-
NC_000005.9:g.112043103C>T	324	APC	Uncertain significance	rs1750556409	RCV001306793;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043103	112043103	C	T	112043103	-
NC_000005.9:g.112043103C>G	324	APC	Uncertain significance	-1	RCV001366602;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043103	112043103	C	G	112043103	-
NC_000005.9:g.112043104C>A	324	APC	Uncertain significance	-1	RCV001360304;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043104	112043104	C	A	112043104	-
NM_000038.5(APC):c.-30536C>G	324	APC	Uncertain significance	rs989021062	RCV000646674;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043105	112043105	C	G	5:g.112043105C>G	ClinGen:CA124924626	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043105C>T	324	APC	Uncertain significance	rs989021062	RCV001319613;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043105	112043105	C	T	112043105	-
NM_000038.5(APC):c.-30535G>C	324	APC	Uncertain significance	rs1020543876	RCV000646696;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043106	112043106	G	C	5:g.112043106G>C	ClinGen:CA658796593	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043106G>A	324	APC	Uncertain significance	rs1020543876	RCV001295213;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043106	112043106	G	A	112043106	-
NC_000005.9:g.112043106G>T	324	APC	Uncertain significance	-1	RCV001368770;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043106	112043106	G	T	112043106	-
NC_000005.9:g.112043107G>A	324	APC	Uncertain significance	-1	RCV001368267;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043107	112043107	G	A	112043107	-
NC_000005.9:g.112043108C>T	324	APC	Uncertain significance	-1	RCV002017468;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043108	112043108	C	T	112043108	-
NM_000038.5(APC):c.-30532A>T	324	APC	Uncertain significance	rs1012461653	RCV000535175;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043109	112043109	A	T	NC_000005.9:g.112043109A>T	ClinGen:CA561890092	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30532A>C	324	APC	Uncertain significance	rs1012461653	RCV000646668;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043109	112043109	A	C	5:g.112043109A>C	ClinGen:CA124924639	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.-30532A>G	324	APC	Uncertain significance	rs1012461653	RCV000813084;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043109	112043109	A	G	5:g.112043109A>G	-
NC_000005.9:g.112043109del	324	APC	Uncertain significance	rs1750557687	RCV001325859;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043109	112043109	CA	C	112043108	-
NM_000038.5(APC):c.-30531A>T	324	APC	Uncertain significance	rs1345543059	RCV000559119;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043110	112043110	A	T	NC_000005.9:g.112043110A>T	ClinGen:CA658655873	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.-30531A>G	324	APC	Uncertain significance	rs1345543059	RCV000824336;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043110	112043110	A	G	5:g.112043110A>G	-
NM_000038.5(APC):c.-30530G>A	324	APC	Uncertain significance	rs1432662523	RCV000529702;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043111	112043111	G	A	NC_000005.9:g.112043111G>A	ClinGen:CA658655875	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30530G>T	324	APC	Uncertain significance	rs1432662523	RCV000546713;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043111	112043111	G	T	NC_000005.9:g.112043111G>T	ClinGen:CA658655874	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.-30529C>T	324	APC	Uncertain significance	rs1580995550	RCV000802908;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043112	112043112	C	T	5:g.112043112C>T	-
NC_000005.9:g.112043112C>G	324	APC	Uncertain significance	rs1580995550	RCV001340063;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043112	112043112	C	G	112043112	-
NC_000005.9:g.112043112C>A	324	APC	Uncertain significance	-1	RCV001891258;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043112	112043112	C	A	112043112	-
NM_000038.5(APC):c.-30528G>T	324	APC	Uncertain significance	rs1373788988	RCV000646666;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043113	112043113	G	T	5:g.112043113G>T	ClinGen:CA658796594	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043113G>C	324	APC	Uncertain significance	-1	RCV001359165;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043113	112043113	G	C	112043113	-
NM_000038.6(APC):c.-30527G>C	324	APC	Uncertain significance	rs1173265814	RCV000798344;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043114	112043114	G	C	5:g.112043114G>C	-
NC_000005.9:g.112043114G>A	324	APC	Uncertain significance	rs1173265814	RCV001312800;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043114	112043114	G	A	112043114	-
NM_000038.5(APC):c.-30526A>C	324	APC	Likely benign	rs372923973	RCV000545800;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043115	112043115	A	C	NC_000005.9:g.112043115A>C	ClinGen:CA124924643	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30526A>G	324	APC	Likely benign	rs372923973	RCV000558211;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043115	112043115	A	G	5:g.112043115A>G	ClinGen:CA124924645	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043116G>A	324	APC	Uncertain significance	-1	RCV001900768;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043116	112043116	G	A	112043116	-
NC_000005.9:g.112043116_112043117del	324	APC	Uncertain significance	-1	RCV002038609;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043116	112043117	AGC	A	112043115	-
NM_000038.6(APC):c.-30524C>G	324	APC	Uncertain significance	rs1427438975	RCV000792202;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043117	112043117	C	G	5:g.112043117C>G	-
NC_000005.9:g.112043117C>A	324	APC	Uncertain significance	rs1427438975	RCV001298739;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043117	112043117	C	A	112043117	-
NC_000005.9:g.112043117C>T	324	APC	Uncertain significance	rs1427438975	RCV001296008;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043117	112043117	C	T	112043117	-
NC_000005.9:g.112043119C>A	324	APC	Uncertain significance	rs1750559277	RCV001304786;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043119	112043119	C	A	112043119	-
NC_000005.9:g.112043120A>C	324	APC	Uncertain significance	-1	RCV001908102;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043120	112043120	A	C	112043120	-
NC_000005.9:g.112043121G>C	324	APC	Uncertain significance	rs1185261719	RCV001308961;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043121	112043121	G	C	112043121	-
NM_000038.6(APC):c.-30517C>T	324	APC	Uncertain significance	rs1580995582	RCV000814358;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043124	112043124	C	T	5:g.112043124C>T	-
NC_000005.9:g.112043124C>A	324	APC	Uncertain significance	rs1580995582	RCV001325089;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043124	112043124	C	A	112043124	-
NC_000005.9:g.112043125C>T	324	APC	Uncertain significance	-1	RCV001906062;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043125	112043125	C	T	112043125	-
NC_000005.9:g.112043125C>A	324	APC	Uncertain significance	-1	RCV002008885;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043125	112043125	C	A	112043125	-
NC_000005.9:g.112043126C>T	324	APC	Uncertain significance	rs1343144964	RCV001349875;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043126	112043126	C	T	112043126	-
NC_000005.9:g.112043127A>G	324	APC	Uncertain significance	-1	RCV001893270;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043127	112043127	A	G	112043127	-
NM_000038.6(APC):c.-30513T>A	324	APC	Uncertain significance	rs532048458	RCV000805520;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043128	112043128	T	A	5:g.112043128T>A	-
NM_000038.6(APC):c.-30513T>C	324	APC	Uncertain significance	rs532048458	RCV000802545;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043128	112043128	T	C	5:g.112043128T>C	-
NC_000005.9:g.112043128T>G	324	APC	Uncertain significance	rs532048458	RCV001300887;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043128	112043128	T	G	112043128	-
NC_000005.9:g.112043129T>C	324	APC	Uncertain significance	-1	RCV001968100;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043129	112043129	T	C	112043129	-
NM_000038.6(APC):c.-30511G>A	324	APC	Uncertain significance	rs550204383	RCV000791902;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043130	112043130	G	A	5:g.112043130G>A	-
NC_000005.9:g.112043132G>C	324	APC	Uncertain significance	rs781399686	RCV001318160;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043132	112043132	G	C	112043132	-
NC_000005.9:g.112043132G>T	324	APC	Uncertain significance	-1	RCV001892013;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043132	112043132	G	T	112043132	-
NC_000005.9:g.112043133C>T	324	APC	Uncertain significance	-1	RCV001943759;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043133	112043133	C	T	112043133	-
NM_000038.6(APC):c.-30507_-30493del	324	APC	Uncertain significance	rs1219201829	RCV000791744;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043134	112043148	CGCCTGCGCATAACAG	C	5:g.112043132_112043146del	-
NC_000005.9:g.112043134C>G	324	APC	Uncertain significance	rs978748301	RCV001308041;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043134	112043134	C	G	112043134	-
NC_000005.9:g.112043134C>T	324	APC	Uncertain significance	rs978748301	RCV001299748;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043134	112043134	C	T	112043134	-
NM_000038.5(APC):c.-30506T>C	324	APC	Uncertain significance	rs1279143171	RCV000646601;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043135	112043135	T	C	NC_000005.9:g.112043135T>C	ClinGen:CA658796595	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043136G>A	324	APC	Uncertain significance	rs1750561418	RCV001337735;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043136	112043136	G	A	112043136	-
NM_000038.6(APC):c.-30504C>A	324	APC	Uncertain significance	rs968227350	RCV000799327;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043137	112043137	C	A	5:g.112043137C>A	-
NC_000005.9:g.112043137C>T	324	APC	Uncertain significance	-1	RCV002033140;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043137	112043137	C	T	112043137	-
NM_000038.5(APC):c.-30503G>A	324	APC	Uncertain significance	rs979191484	RCV000533333;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043138	112043138	G	A	NC_000005.9:g.112043138G>A	ClinGen:CA124924671	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30502C>A	324	APC	Uncertain significance	rs1313658633	RCV000540297;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043139	112043139	C	A	NC_000005.9:g.112043139C>A	ClinGen:CA561890095	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30502C>T	324	APC	Uncertain significance	rs1313658633	RCV000552792;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043139	112043139	C	T	NC_000005.9:g.112043139C>T	ClinGen:CA658655876	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043139C>G	324	APC	Uncertain significance	rs1313658633	RCV001348303;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043139	112043139	C	G	112043139	-
NM_000038.5(APC):c.-30501A>G	324	APC	Uncertain significance	rs911239343	RCV000646569;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043140	112043140	A	G	5:g.112043140A>G	ClinGen:CA124924675	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30501A>T	324	APC	Uncertain significance	rs911239343	RCV000646532;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043140	112043140	A	T	NC_000005.9:g.112043140A>T	ClinGen:CA658796596	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30500T>C	324	APC	Uncertain significance	rs1213502095	RCV000646605;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043141	112043141	T	C	NC_000005.9:g.112043141T>C	ClinGen:CA658796597	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043141T>A	324	APC	Uncertain significance	rs1213502095	RCV001308597;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043141	112043141	T	A	112043141	-
NC_000005.9:g.112043142A>G	324	APC	Uncertain significance	rs1750562759	RCV001309011;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043142	112043142	A	G	112043142	-
NC_000005.9:g.112043144C>G	324	APC	Uncertain significance	rs1750562869	RCV001323606;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043144	112043144	C	G	112043144	-
NM_000038.6(APC):c.-30496A>G	324	APC	Uncertain significance	rs1412978804	RCV000813077;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043145	112043145	A	G	5:g.112043145A>G	-
NM_000038.6(APC):c.-30495G>A	324	APC	Uncertain significance	rs1031191403	RCV000796682;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043146	112043146	G	A	5:g.112043146G>A	-
NC_000005.9:g.112043146G>T	324	APC	Uncertain significance	-1	RCV002045660;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043146	112043146	G	T	112043146	-
NM_000038.5(APC):c.-30493C>T	324	APC	Likely benign	rs942777534	RCV000532428;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043148	112043148	C	T	5:g.112043148C>T	ClinGen:CA124924686	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043148C>A	324	APC	Uncertain significance	rs942777534	RCV001317863;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043148	112043148	C	A	112043148	-
NM_000038.5(APC):c.-30492T>C	324	APC	Uncertain significance	rs866427693	RCV000646686;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043149	112043149	T	C	5:g.112043149T>C	ClinGen:CA124924689	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043150C>G	324	APC	Uncertain significance	-1	RCV001909467;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043150	112043150	C	G	112043150	-
NC_000005.9:g.112043150C>T	324	APC	Uncertain significance	-1	RCV001884066;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043150	112043150	C	T	112043150	-
NM_000038.5(APC):c.-30490T>C	324	APC	Uncertain significance	rs1280021363	RCV000646612;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043151	112043151	T	C	5:g.112043151T>C	ClinGen:CA658796598	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.-30489A>C	324	APC	Uncertain significance	rs956500063	RCV000806280;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043152	112043152	A	C	5:g.112043152A>C	-
NC_000005.9:g.112043152A>G	324	APC	Uncertain significance	rs956500063	RCV001305505;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043152	112043152	A	G	112043152	-
NC_000005.9:g.112043153G>T	324	APC	Uncertain significance	-1	RCV002022275;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043153	112043153	G	T	112043153	-
NM_000038.5(APC):c.-30487T>C	324	APC	Uncertain significance	rs1312495728	RCV000556365;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043154	112043154	T	C	NC_000005.9:g.112043154T>C	ClinGen:CA658655877	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30487T>A	324	APC	Uncertain significance	rs1312495728	RCV000646643;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043154	112043154	T	A	5:g.112043154T>A	ClinGen:CA658796599	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043154T>G	324	APC	Uncertain significance	-1	RCV001879045;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043154	112043154	T	G	112043154	-
NM_000038.5(APC):c.-30486C>G	324	APC	Uncertain significance	rs748588164	RCV000539378;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043155	112043155	C	G	NC_000005.9:g.112043155C>G	ClinGen:CA124924699	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043155C>T	324	APC	Uncertain significance	rs748588164	RCV001349728;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043155	112043155	C	T	112043155	-
NC_000005.9:g.112043156T>C	324	APC	Uncertain significance	-1	RCV001362462;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043156	112043156	T	C	112043156	-
NM_000038.5(APC):c.-30484C>A	324	APC	Uncertain significance	rs1554060161	RCV000646581;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043157	112043157	C	A	5:g.112043157C>A	ClinGen:CA658796600	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043157C>T	324	APC	Uncertain significance	-1	RCV001940802;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043157	112043157	C	T	112043157	-
NC_000005.9:g.112043158C>T	324	APC	Uncertain significance	rs1360948145	RCV001300737;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043158	112043158	C	T	112043158	-
NC_000005.9:g.112043158C>G	324	APC	Uncertain significance	-1	RCV001362864;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043158	112043158	C	G	112043158	-
NM_000038.5(APC):c.-30482G>C	324	APC	Uncertain significance	rs1409487828	RCV000526915;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043159	112043159	G	C	5:g.112043159G>C	ClinGen:CA658655878	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.-30482G>A	324	APC	Uncertain significance	rs1409487828	RCV000816322;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043159	112043159	G	A	5:g.112043159G>A	-
NM_000038.6(APC):c.-30481G>T	324	APC	Uncertain significance	rs1580995745	RCV000818050;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043160	112043160	G	T	5:g.112043160G>T	-
NM_000038.5(APC):c.-30479C>A	324	APC	Uncertain significance	rs1424887097	RCV000646690;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043162	112043162	C	A	NC_000005.9:g.112043162C>A	ClinGen:CA658796601	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043162C>T	324	APC	Uncertain significance	-1	RCV001363118;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043162	112043162	C	T	112043162	-
NM_000038.5(APC):c.-30478T>C	324	APC	Uncertain significance	rs931845291	RCV000550858;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043163	112043163	T	C	NC_000005.9:g.112043163T>C	ClinGen:CA124924708	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043164G>C	324	APC	Uncertain significance	-1	RCV002036758;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043164	112043164	G	C	112043164	-
NC_000005.9:g.112043164G>A	324	APC	Uncertain significance	-1	RCV001975409;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043164	112043164	G	A	112043164	-
NM_000038.5(APC):c.-30476T>C	324	APC	Uncertain significance	rs538243333	RCV000646537;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043165	112043165	T	C	5:g.112043165T>C	ClinGen:CA124924709	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30476T>G	324	APC	Uncertain significance	rs538243333	RCV000646626;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043165	112043165	T	G	NC_000005.9:g.112043165T>G	ClinGen:CA561890103	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043165T>A	324	APC	Uncertain significance	-1	RCV001897709;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043165	112043165	T	A	112043165	-
NC_000005.9:g.112043166G>C	324	APC	Uncertain significance	rs1257302588	RCV001308887;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043166	112043166	G	C	112043166	-
NC_000005.9:g.112043167G>A	324	APC	Uncertain significance	-1	RCV001366282;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043167	112043167	G	A	112043167	-
NM_000038.5(APC):c.-30471A>C	324	APC	Benign	rs75580617	RCV000430440\|RCV000646587\|RCV001810903;	N	MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112043170	112043170	A	C	5:g.112043170A>C	ClinGen:CA12120713	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30467A>C	324	APC	Benign	rs190326008	RCV000526023;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043174	112043174	A	C	5:g.112043174A>C	ClinGen:CA658655879	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30467A>G	324	APC	Benign	rs190326008	RCV000538385;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043174	112043174	A	G	NC_000005.9:g.112043174A>G	ClinGen:CA124924764	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30467delA	324	APC	Benign	rs201014315	RCV000601483\|RCV000861801;	N	MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043174	112043174	CA	C	NC_000005.9:g.112043174del	ClinGen:CA124924761	CN169374 not specified;
NM_000038.5(APC):c.-30466G>C	324	APC	Benign	rs59923692	RCV000550019\|RCV000606361;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374	5	112043175	112043175	G	C	5:g.112043175G>C	ClinGen:CA124924769	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043175G>A	324	APC	Uncertain significance	rs59923692	RCV001296122;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043175	112043175	G	A	112043175	-
NC_000005.9:g.112043175G>T	324	APC	Uncertain significance	rs59923692	RCV001318900;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043175	112043175	G	T	112043175	-
NC_000005.9:g.112043175del	324	APC	Benign	-1	RCV002218719;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043175	112043175	AG	A	112043174	-
NC_000005.9:g.112043176_112043178del	324	APC	Uncertain significance	rs1750567053	RCV001305524;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043176	112043178	GCAA	G	112043175	-
NC_000005.9:g.112043176C>T	324	APC	Uncertain significance	-1	RCV001360360;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043176	112043176	C	T	112043176	-
NC_000005.9:g.112043176C>G	324	APC	Uncertain significance	-1	RCV001965627;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043176	112043176	C	G	112043176	-
NC_000005.9:g.112043177A>G	324	APC	Uncertain significance	rs1750567134	RCV001343123;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043177	112043177	A	G	112043177	-
NM_000038.5(APC):c.-30460C>T	324	APC	Likely benign	rs145818737	RCV000537525;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043181	112043181	C	T	5:g.112043181C>T	ClinGen:CA124924773	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30460C>G	324	APC	Uncertain significance	rs145818737	RCV000646670;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043181	112043181	C	G	5:g.112043181C>G	ClinGen:CA658796602	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.5(APC):c.-30459C>T	324	APC	Uncertain significance	rs1333841760	RCV000556955;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043182	112043182	C	T	NC_000005.9:g.112043182C>T	ClinGen:CA658655880	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043182C>A	324	APC	Uncertain significance	rs1333841760	RCV001306238;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043182	112043182	C	A	112043182	-
NC_000005.9:g.112043182C>G	324	APC	Uncertain significance	rs1333841760	RCV001316721;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043182	112043182	C	G	112043182	-
NC_000005.9:g.112043182_112043183del	324	APC	Uncertain significance	-1	RCV001896571;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043182	112043183	CCT	C	112043181	-
NM_000038.5(APC):c.-30458T>C	324	APC	Uncertain significance	rs1554060175	RCV000549089;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043183	112043183	T	C	NC_000005.9:g.112043183T>C	ClinGen:CA658655881	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043184C>G	324	APC	Uncertain significance	rs1750567665	RCV001344799;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043184	112043184	C	G	112043184	-
NC_000005.9:g.112043184C>T	324	APC	Uncertain significance	-1	RCV001366743;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043184	112043184	C	T	112043184	-
NC_000005.9:g.112043185T>C	324	APC	Uncertain significance	-1	RCV002017008;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043185	112043185	T	C	112043185	-
NC_000005.9:g.112043186C>T	324	APC	Uncertain significance	-1	RCV001995604;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043186	112043186	C	T	112043186	-
NM_000038.5(APC):c.-30453C>G	324	APC	Uncertain significance	rs1554060178	RCV000536592;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043188	112043188	C	G	NC_000005.9:g.112043188C>G	ClinGen:CA658655882	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.112043190C>T	324	APC	Uncertain significance	-1	RCV001881339;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043190	112043190	C	T	112043190	-
NM_000038.6(APC):c.-30450A>G	324	APC	Uncertain significance	rs1293734316	RCV000809203;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043191	112043191	A	G	5:g.112043191A>G	-
NM_001127511.3(APC):c.-220G>A	324	APC	Uncertain significance	rs1381567636	RCV000805417;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043195	112043195	G	A	5:g.112043195G>A	-
NM_001127511.3(APC):c.-219C>T	324	APC	Likely benign	rs1178835678	RCV000560546;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043196	112043196	C	T	5:g.112043196C>T	ClinGen:CA561890110	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-218A>G	324	APC	Uncertain significance	rs1554060180	RCV000646571;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043197	112043197	A	G	5:g.112043197A>G	ClinGen:CA658796603	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-217T>C	324	APC	Uncertain significance	rs1750568152	RCV001340837;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043198	112043198	T	C	112043198	-
NM_001127511.3(APC):c.-215G>A	324	APC	Uncertain significance	rs1750568226	RCV001345742;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043200	112043200	G	A	112043200	-
APC deletion	324	APC	Pathogenic	-1	RCV000000877;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043201	112181937	na	na		OMIM:611731.0042	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-214T>C	324	APC	Uncertain significance	rs1580995847	RCV000820804;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043201	112043201	T	C	5:g.112043201T>C	-
NM_001127511.3(APC):c.-213A>G	324	APC	Uncertain significance	rs1554060181	RCV000646636;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043202	112043202	A	G	NC_000005.9:g.112043202A>G	ClinGen:CA658796604	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-213A>T	324	APC	Uncertain significance	rs1554060181	RCV000795000;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043202	112043202	A	T	5:g.112043202A>T	-
NM_001127511.3(APC):c.-212G>A	324	APC	Uncertain significance	rs930090983	RCV000543614;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043203	112043203	G	A	5:g.112043203G>A	ClinGen:CA124924783	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-210C>T	324	APC	Uncertain significance	-1	RCV001362162;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043205	112043205	C	T	112043205	-
NM_001127511.3(APC):c.-208T>C	324	APC	Uncertain significance	rs1750568725	RCV001307229;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043207	112043207	T	C	112043207	-
NM_001127511.3(APC):c.-206C>T	324	APC	Uncertain significance	-1	RCV001372256;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043209	112043209	C	T	112043209	-
NM_001127511.3(APC):c.-205C>T	324	APC	Uncertain significance	rs1750569011	RCV001315985;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043210	112043210	C	T	112043210	-
NM_001127511.3(APC):c.-205C>G	324	APC	Uncertain significance	rs1750569011	RCV001340516;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043210	112043210	C	G	112043210	-
NM_001127511.3(APC):c.-204A>G	324	APC	Conflicting interpretations of pathogenicity	rs554351451	RCV000535658\|RCV000764556;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:C1851124,OMIM:135290, Orphanet:873; MONDO:MONDO:0002032,MedGen:C0699790; Human Phenotype Ontology:HP:0001402,Human Phenotype Ontology:HP:0002899,Human Phenotype Ontology:HP:0003007,Human Phenotype Onto	5	112043211	112043211	A	G	NC_000005.9:g.112043211A>G	ClinGen:CA124924789	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-203C>A	324	APC	Uncertain significance	-1	RCV001368327;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043212	112043212	C	A	112043212	-
NM_001127511.3(APC):c.-203C>T	324	APC	Uncertain significance	-1	RCV001359292;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043212	112043212	C	T	112043212	-
NM_001127511.3(APC):c.-201T>C	324	APC	Uncertain significance	rs1580995876	RCV000818007;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043214	112043214	T	C	5:g.112043214T>C	-
NM_001127511.3(APC):c.-200C>A	324	APC	Uncertain significance	rs1460379840	RCV001323355;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043215	112043215	C	A	112043215	-
NM_001127511.3(APC):c.-200C>T	324	APC	Uncertain significance	-1	RCV001372420;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043215	112043215	C	T	112043215	-
NM_001127511.3(APC):c.-199C>G	324	APC	Uncertain significance	-1	RCV001361281;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043216	112043216	C	G	112043216	-
NM_001127511.3(APC):c.-199C>T	324	APC	Likely benign	-1	RCV001437739;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043216	112043216	C	T	112043216	-
NM_001127511.3(APC):c.-197A>C	324	APC	Uncertain significance	rs1750570165	RCV001302796;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043218	112043218	A	C	112043218	-
NM_001127511.3(APC):c.-197A>T	324	APC	Uncertain significance	rs1750570165	RCV001327548;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043218	112043218	A	T	112043218	-
NM_001127511.3(APC):c.-197A>G	324	APC	Uncertain significance	-1	RCV001365772;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043218	112043218	A	G	112043218	-
NM_001127511.3(APC):c.-196C>T	324	APC	Uncertain significance	-1	RCV001374016;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043219	112043219	C	T	112043219	-
NM_001127511.3(APC):c.-193G>A	324	APC	Uncertain significance	rs1750570441	RCV001180770\|RCV001363069;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043222	112043222	G	A	5:g.112043222G>A	-
NM_001127511.3(APC):c.-193G>C	324	APC	Uncertain significance	-1	RCV001362461;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043222	112043222	G	C	112043222	-
NM_001127511.3(APC):c.-192A>G	324	APC	Likely pathogenic	rs879253784	RCV000234977\|RCV001290976\|RCV001552789;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0017790,MedGen:C4749917,OMIM:619182, Orphanet:314022\|MedGen:CN517202	5	112043223	112043223	A	G	NC_000005.9:g.112043223A>G	ClinGen:CA10584053,OMIM:611731.0055	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-192A>T	324	APC	Pathogenic	rs879253784	RCV000234988;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043223	112043223	A	T	NC_000005.9:g.112043223A>T	ClinGen:CA10584054,OMIM:611731.0056	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-192_-191delinsTAGCAAGGG	324	APC	Likely pathogenic	rs1580995904	RCV000808449;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043223	112043224	AT	TAGCAAGGG	5:g.112043223_112043224insAGCAAGGG	-
NM_001127511.3(APC):c.-191T>C	324	APC	Pathogenic	rs879253783	RCV000234996\|RCV001013699\|RCV001290975\|RCV001559545;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0017790,MedGen:C4749917,OMIM:619182, Orphanet:314022\|MedGen:CN517202	5	112043224	112043224	T	C	NC_000005.9:g.112043224T>C	ClinGen:CA10584052,OMIM:611731.0054	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-190G>A	324	APC	Pathogenic	rs879253785	RCV000234994;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043225	112043225	G	A	NC_000005.9:g.112043225G>A	ClinGen:CA10584055,OMIM:611731.0057	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-189G>A	324	APC	Uncertain significance	-1	RCV002043144;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043226	112043226	G	A	112043226	-
NM_001127511.3(APC):c.-188C>T	324	APC	Conflicting interpretations of pathogenicity	rs761454123	RCV000547204\|RCV001524617;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112043227	112043227	C	T	NC_000005.9:g.112043227C>T	ClinGen:CA124924833	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-188C>A	324	APC	Uncertain significance	-1	RCV002048256;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043227	112043227	C	A	112043227	-
NM_001127511.3(APC):c.-187G>A	324	APC	Uncertain significance	rs1554060186	RCV000530192\|RCV001185228;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112043228	112043228	G	A	NC_000005.9:g.112043228G>A	ClinGen:CA658655883	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-186G>T	324	APC	Uncertain significance	rs1554060187	RCV000646673;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043229	112043229	G	T	5:g.112043229G>T	ClinGen:CA658796605	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-186G>A	324	APC	Uncertain significance	rs1554060187	RCV001345503;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043229	112043229	G	A	112043229	-
NM_001127511.3(APC):c.-185A>C	324	APC	Uncertain significance	rs1433000483	RCV001299896;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043230	112043230	A	C	112043230	-
NM_001127511.3(APC):c.-184G>C	324	APC	Uncertain significance	rs575784409	RCV000554174;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043231	112043231	G	C	5:g.112043231G>C	ClinGen:CA124924854	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-184G>A	324	APC	Uncertain significance	rs575784409	RCV001303319;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043231	112043231	G	A	112043231	-
NM_001127511.3(APC):c.-183G>A	324	APC	Uncertain significance	rs892252479	RCV000806696;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043232	112043232	G	A	5:g.112043232G>A	-
NM_001127511.3(APC):c.-182G>T	324	APC	Uncertain significance	rs1554060189	RCV000529263;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043233	112043233	G	T	NC_000005.9:g.112043233G>T	ClinGen:CA658655884	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-182G>A	324	APC	Uncertain significance	-1	RCV001361723;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043233	112043233	G	A	112043233	-
NM_001127511.3(APC):c.-181C>T	324	APC	Benign/Likely benign	rs115658307	RCV000553273\|RCV000614459\|RCV001811056;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374\|MedGen:CN517202	5	112043234	112043234	C	T	NC_000005.9:g.112043234C>T	ClinGen:CA124924856	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-180A>T	324	APC	Uncertain significance	-1	RCV001369380;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043235	112043235	A	T	112043235	-
NM_001127511.3(APC):c.-179A>G	324	APC	Uncertain significance	-1	RCV001919358;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043236	112043236	A	G	112043236	-
NM_001127511.3(APC):c.-178G>A	324	APC	Uncertain significance	rs1045323633	RCV000646544;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043237	112043237	G	A	5:g.112043237G>A	ClinGen:CA124924858	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-178G>C	324	APC	Uncertain significance	-1	RCV001366624;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043237	112043237	G	C	112043237	-
NM_001127511.3(APC):c.-177dup	324	APC	Uncertain significance	-1	RCV001367509;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043237	112043238	G	GT	112043237	-
NM_001127511.3(APC):c.-177T>A	324	APC	Uncertain significance	rs1020491376	RCV000540833;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043238	112043238	T	A	5:g.112043238T>A	ClinGen:CA658655885	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-177T>C	324	APC	Uncertain significance	rs1020491376	RCV000646603;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043238	112043238	T	C	NC_000005.9:g.112043238T>C	ClinGen:CA658796606	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-175G>C	324	APC	Uncertain significance	rs1334013498	RCV001324703;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043240	112043240	G	C	112043240	-
NM_001127511.3(APC):c.-174C>A	324	APC	Uncertain significance	rs1580995974	RCV000807200;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043241	112043241	C	A	5:g.112043241C>A	-
NM_001127511.3(APC):c.-174C>T	324	APC	Uncertain significance	rs1580995974	RCV001326635;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043241	112043241	C	T	112043241	-
NM_001127511.3(APC):c.-173A>G	324	APC	Uncertain significance	rs1273775271	RCV000528391;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043242	112043242	A	G	NC_000005.9:g.112043242A>G	ClinGen:CA658655886	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-172A>T	324	APC	Uncertain significance	rs1580995983	RCV000792324;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043243	112043243	A	T	5:g.112043243A>T	-
NM_001127511.3(APC):c.-167dup	324	APC	Benign	-1	RCV001521009;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043243	112043244	A	AG	112043243	-
NM_001127511.3(APC):c.-171G>C	324	APC	Uncertain significance	rs968943120	RCV000646576;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043244	112043244	G	C	5:g.112043244G>C	ClinGen:CA124924868	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-171G>A	324	APC	Uncertain significance	rs968943120	RCV000798515;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043244	112043244	G	A	5:g.112043244G>A	-
NM_001127511.3(APC):c.-171G>T	324	APC	Uncertain significance	rs968943120	RCV001302806;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043244	112043244	G	T	112043244	-
NM_001127511.3(APC):c.-170G>C	324	APC	Uncertain significance	rs1000470082	RCV000552392;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043245	112043245	G	C	5:g.112043245G>C	ClinGen:CA124924875	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-170G>T	324	APC	Uncertain significance	rs1000470082	RCV001304929;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043245	112043245	G	T	112043245	-
NM_001127511.3(APC):c.-170G>A	324	APC	Uncertain significance	-1	RCV001373613;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043245	112043245	G	A	112043245	-
NM_001127511.3(APC):c.-169G>A	324	APC	Uncertain significance	rs1750575005	RCV001324118;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043246	112043246	G	A	112043246	-
NM_001127511.3(APC):c.-168G>A	324	APC	Uncertain significance	rs1554060194	RCV000646596;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043247	112043247	G	A	5:g.112043247G>A	ClinGen:CA658796607	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-168G>T	324	APC	Uncertain significance	rs1554060194	RCV001302234;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043247	112043247	G	T	112043247	-
NM_001127511.3(APC):c.-167G>A	324	APC	Uncertain significance	rs1278244063	RCV000539909;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043248	112043248	G	A	NC_000005.9:g.112043248G>A	ClinGen:CA561890248	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-166C>G	324	APC	Uncertain significance	rs904001781	RCV000551432;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043249	112043249	C	G	NC_000005.9:g.112043249C>G	ClinGen:CA658655887	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-166C>T	324	APC	Benign	rs904001781	RCV000527458;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043249	112043249	C	T	NC_000005.9:g.112043249C>T	ClinGen:CA124924880	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-166C>A	324	APC	Uncertain significance	rs904001781	RCV000534399;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043249	112043249	C	A	5:g.112043249C>A	ClinGen:CA658655888	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-165G>A	324	APC	Uncertain significance	rs1580996027	RCV000809435;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043250	112043250	G	A	5:g.112043250G>A	-
NM_001127511.3(APC):c.-165G>C	324	APC	Uncertain significance	rs1580996027	RCV001321643;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043250	112043250	G	C	112043250	-
NM_001127511.3(APC):c.-165G>T	324	APC	Uncertain significance	rs1580996027	RCV001314742;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043250	112043250	G	T	112043250	-
NM_001127511.3(APC):c.-164G>A	324	APC	Uncertain significance	rs1750576080	RCV001320136;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043251	112043251	G	A	112043251	-
NM_001127511.3(APC):c.-164G>C	324	APC	Uncertain significance	rs1750576080	RCV001343771;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043251	112043251	G	C	112043251	-
NM_001127511.3(APC):c.-163G>A	324	APC	Uncertain significance	rs558562104	RCV000646539;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043252	112043252	G	A	5:g.112043252G>A	ClinGen:CA124924885	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-163G>C	324	APC	Uncertain significance	rs558562104	RCV001318360;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043252	112043252	G	C	112043252	-
NM_001127511.3(APC):c.-163G>T	324	APC	Uncertain significance	-1	RCV001918352;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043252	112043252	G	T	112043252	-
NM_001127511.3(APC):c.-162G>A	324	APC	Uncertain significance	-1	RCV002009056;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043253	112043253	G	A	112043253	-
NM_001127511.3(APC):c.-161T>A	324	APC	Uncertain significance	-1	RCV001991140;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043254	112043254	T	A	112043254	-
NM_001127511.3(APC):c.-161T>C	324	APC	Uncertain significance	-1	RCV002013927;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043254	112043254	T	C	112043254	-
NM_001127511.3(APC):c.-160G>A	324	APC	Uncertain significance	-1	RCV001361231;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043255	112043255	G	A	112043255	-
NM_001127511.3(APC):c.-159T>C	324	APC	Uncertain significance	rs1750576513	RCV001350673;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043256	112043256	T	C	112043256	-
NM_001127511.3(APC):c.-158G>C	324	APC	Uncertain significance	rs1750576619	RCV001320007;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043257	112043257	G	C	112043257	-
NM_001127511.3(APC):c.-157G>A	324	APC	Uncertain significance	rs1554060197	RCV000526505;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043258	112043258	G	A	NC_000005.9:g.112043258G>A	ClinGen:CA658655889	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-156C>A	324	APC	Uncertain significance	rs1031181133	RCV000646616;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043259	112043259	C	A	NC_000005.9:g.112043259C>A	ClinGen:CA658796608	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-156C>T	324	APC	Uncertain significance	rs1031181133	RCV000646625;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043259	112043259	C	T	5:g.112043259C>T	ClinGen:CA124924889	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-155C>A	324	APC	Uncertain significance	rs1750576936	RCV001297397;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043260	112043260	C	A	112043260	-
NM_001127511.3(APC):c.-155C>T	324	APC	Uncertain significance	rs1750576936	RCV001323662;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043260	112043260	C	T	112043260	-
NM_001127511.3(APC):c.-154G>C	324	APC	Uncertain significance	rs1750577100	RCV001294634;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043261	112043261	G	C	112043261	-
NM_001127511.3(APC):c.-154G>A	324	APC	Uncertain significance	rs1750577100	RCV001325552;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043261	112043261	G	A	112043261	-
NM_001127511.3(APC):c.-154G>T	324	APC	Uncertain significance	rs1750577100	RCV001343031;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043261	112043261	G	T	112043261	-
NM_001127511.3(APC):c.-153C>T	324	APC	Uncertain significance	rs956623923	RCV000806610;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043262	112043262	C	T	5:g.112043262C>T	-
NM_001127511.3(APC):c.-152C>T	324	APC	Benign	rs138386816	RCV000550553\|RCV000616769\|RCV002060337;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374\|MedGen:CN517202	5	112043263	112043263	C	T	5:g.112043263C>T	ClinGen:CA124924898	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-151G>C	324	APC	Likely benign	rs1029997545	RCV000538059;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043264	112043264	G	C	NC_000005.9:g.112043264G>C	ClinGen:CA124924903	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-151G>A	324	APC	Uncertain significance	-1	RCV001365609;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043264	112043264	G	A	112043264	-
NM_001127511.3(APC):c.-150G>A	324	APC	Uncertain significance	rs1459755551	RCV000557474;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043265	112043265	G	A	NC_000005.9:g.112043265G>A	ClinGen:CA658655890	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-150G>C	324	APC	Uncertain significance	rs1459755551	RCV000816276;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043265	112043265	G	C	5:g.112043265G>C	-
NM_001127511.3(APC):c.-149A>C	324	APC	Uncertain significance	rs922676017	RCV000545084;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043266	112043266	A	C	NC_000005.9:g.112043266A>C	ClinGen:CA124924908	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-148A>C	324	APC	Uncertain significance	rs953056092	RCV000819026;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043267	112043267	A	C	5:g.112043267A>C	-
NM_001127511.3(APC):c.-148A>G	324	APC	Uncertain significance	rs953056092	RCV001348151;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043267	112043267	A	G	112043267	-
NM_001127511.3(APC):c.-148A>T	324	APC	Uncertain significance	rs953056092	RCV001348176;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043267	112043267	A	T	112043267	-
NM_001127511.3(APC):c.-147G>A	324	APC	Likely benign	rs1208195997	RCV000793187;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043268	112043268	G	A	5:g.112043268G>A	-
NM_001127511.3(APC):c.-147G>T	324	APC	Uncertain significance	-1	RCV001898946;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043268	112043268	G	T	112043268	-
NM_001127511.3(APC):c.-146C>T	324	APC	Uncertain significance	rs1554060206	RCV000537140;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043269	112043269	C	T	5:g.112043269C>T	ClinGen:CA658655891	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-146C>G	324	APC	Uncertain significance	rs1554060206	RCV001346980;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043269	112043269	C	G	112043269	-
NM_001127511.3(APC):c.-145C>G	324	APC	Uncertain significance	rs986030414	RCV000646600;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043270	112043270	C	G	5:g.112043270C>G	ClinGen:CA124924910	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-145C>T	324	APC	Uncertain significance	rs986030414	RCV000792927;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043270	112043270	C	T	5:g.112043270C>T	-
NM_001127511.3(APC):c.-144T>G	324	APC	Uncertain significance	rs1717358972	RCV001316485;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043271	112043271	T	G	112043271	-
NM_001127511.3(APC):c.-144T>C	324	APC	Uncertain significance	rs1717358972	RCV001340331;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043271	112043271	T	C	112043271	-
NM_001127511.3(APC):c.-143A>G	324	APC	Uncertain significance	rs1750579345	RCV001305624;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043272	112043272	A	G	112043272	-
NM_001127511.3(APC):c.-142G>C	324	APC	Uncertain significance	rs951500465	RCV000793786;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043273	112043273	G	C	5:g.112043273G>C	-
NM_001127511.3(APC):c.-142G>A	324	APC	Uncertain significance	rs951500465	RCV001347250;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043273	112043273	G	A	112043273	-
NM_001127511.3(APC):c.-142G>T	324	APC	Uncertain significance	-1	RCV001371139;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043273	112043273	G	T	112043273	-
NM_001127511.3(APC):c.-141C>T	324	APC	Uncertain significance	rs1750579738	RCV001317237;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043274	112043274	C	T	112043274	-
NM_001127511.3(APC):c.-141C>G	324	APC	Uncertain significance	rs1750579738	RCV001342724;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043274	112043274	C	G	112043274	-
NM_001127511.3(APC):c.-140C>G	324	APC	Conflicting interpretations of pathogenicity	rs775297664	RCV000556539\|RCV000762155;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112043275	112043275	C	G	NC_000005.9:g.112043275C>G	ClinGen:CA124924916	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-140C>A	324	APC	Likely benign	rs775297664	RCV000646695;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043275	112043275	C	A	5:g.112043275C>A	ClinGen:CA124924920	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-140C>T	324	APC	Uncertain significance	rs775297664	RCV001347679;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043275	112043275	C	T	112043275	-
NM_001127511.3(APC):c.-139G>C	324	APC	Uncertain significance	rs1554060208	RCV000544155;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043276	112043276	G	C	NC_000005.9:g.112043276G>C	ClinGen:CA658655892	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-139G>A	324	APC	Uncertain significance	rs1554060208	RCV001317238;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043276	112043276	G	A	112043276	-
NM_001127511.3(APC):c.-138C>A	324	APC	Uncertain significance	rs1259973377	RCV001304051;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043277	112043277	C	A	112043277	-
NM_001127511.3(APC):c.-138C>G	324	APC	Uncertain significance	rs1259973377	RCV001306956;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043277	112043277	C	G	112043277	-
NM_001127511.3(APC):c.-138C>T	324	APC	Uncertain significance	-1	RCV001359776;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043277	112043277	C	T	112043277	-
NM_001127511.3(APC):c.-137T>C	324	APC	Uncertain significance	rs1750580599	RCV001351131;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043278	112043278	T	C	112043278	-
NM_001127511.3(APC):c.-137T>G	324	APC	Uncertain significance	-1	RCV001891606;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043278	112043278	T	G	112043278	-
NM_001127511.3(APC):c.-132_-114dup	324	APC	Uncertain significance	-1	RCV001985374;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043278	112043279	T	TGCTCGGGGGGGACCTGCGG	112043278	-
NM_001127511.3(APC):c.-136G>C	324	APC	Uncertain significance	-1	RCV001371993;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043279	112043279	G	C	112043279	-
NM_001127511.3(APC):c.-136G>A	324	APC	Uncertain significance	-1	RCV002045160;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043279	112043279	G	A	112043279	-
NM_001127511.3(APC):c.-135C>T	324	APC	Uncertain significance	rs1311747020	RCV000531681;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043280	112043280	C	T	NC_000005.9:g.112043280C>T	ClinGen:CA658655893	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-135C>G	324	APC	Uncertain significance	rs1311747020	RCV000646534;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043280	112043280	C	G	5:g.112043280C>G	ClinGen:CA658796609	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-134T>C	324	APC	Uncertain significance	rs963346102	RCV000646574;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043281	112043281	T	C	5:g.112043281T>C	ClinGen:CA124924933	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-134T>A	324	APC	Uncertain significance	rs963346102	RCV000646644;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043281	112043281	T	A	5:g.112043281T>A	ClinGen:CA658796610	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-134_-133insGGG	324	APC	Likely benign	rs1561393341	RCV000794578;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043281	112043282	T	TGGG	5:g.112043281_112043282insGGG	-
NM_001127511.3(APC):c.-134_-133insGGGG	324	APC	Uncertain significance	rs1561393341	RCV001306608;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043281	112043282	T	TGGGG	112043281	-
NM_001127511.3(APC):c.-134_-133delinsCG	324	APC	Uncertain significance	rs1750581459	RCV001321180;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043281	112043282	TC	CG	112043281	-
NM_001127511.3(APC):c.-133dup	324	APC	Uncertain significance	-1	RCV001361945;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043281	112043282	T	TC	112043281	-
NM_001127511.3(APC):c.-134_-133insG	324	APC	Benign/Likely benign	-1	RCV001519124\|RCV001562980;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112043281	112043282	T	TG	112043281	-
NM_001127511.3(APC):c.-134_-133insGG	324	APC	Benign	-1	RCV001516816;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043281	112043282	T	TGG	112043281	-
NM_001127511.3(APC):c.-134_-133insGC	324	APC	Uncertain significance	-1	RCV001972938;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043281	112043282	T	TGC	112043281	-
NM_001127511.3(APC):c.-133C>G	324	APC	Benign	rs79896135	RCV000441233\|RCV000646588;	N	MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043282	112043282	C	G	5:g.112043282C>G	ClinGen:CA12132519	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-133C>T	324	APC	Likely benign	rs79896135	RCV000555650;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043282	112043282	C	T	5:g.112043282C>T	ClinGen:CA124924944	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-133C>A	324	APC	Uncertain significance	rs79896135	RCV000646624;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043282	112043282	C	A	5:g.112043282C>A	ClinGen:CA658796611	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-133_-132delinsGC	324	APC	Uncertain significance	rs1580996199	RCV000824519;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043282	112043283	CG	GC	NC_000005.9:g.112043282_112043283delinsGC	-
NM_001127511.3(APC):c.-133_-132insA	324	APC	Uncertain significance	rs1750582620	RCV001307724;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043282	112043283	C	CA	112043282	-
NM_001127511.3(APC):c.-133del	324	APC	Uncertain significance	rs371478422	RCV001325809;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043282	112043282	TC	T	112043281	-
NM_001127511.3(APC):c.-133_-132delinsGA	324	APC	Uncertain significance	-1	RCV001358953;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043282	112043283	CG	GA	112043282	-
NM_001127511.3(APC):c.-133_-131delinsGTC	324	APC	Uncertain significance	-1	RCV001372328;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043282	112043284	CGG	GTC	112043282	-
NM_001127511.3(APC):c.-133_-132delinsGT	324	APC	Benign	-1	RCV001510747;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043282	112043283	CG	GT	112043282	-
NM_001127511.3(APC):c.-127_-126dup	324	APC	Uncertain significance	-1	RCV001877904;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043282	112043283	C	CGG	112043282	-
NM_001127511.3(APC):c.-132G>T	324	APC	Benign/Likely benign	rs182500056	RCV000543232\|RCV000611510;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374	5	112043283	112043283	G	T	NC_000005.9:g.112043283G>T	ClinGen:CA124924948	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-132G>C	324	APC	Likely benign	rs182500056	RCV000530763;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043283	112043283	G	C	5:g.112043283G>C	ClinGen:CA124924947	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-132G>A	324	APC	Uncertain significance	rs182500056	RCV000646608;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043283	112043283	G	A	NC_000005.9:g.112043283G>A	ClinGen:CA658796612	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-132_-131insC	324	APC	Uncertain significance	-1	RCV001361356;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043283	112043284	G	GC	112043283	-
NM_001127511.3(APC):c.-132_-131insT	324	APC	Likely benign	-1	RCV001396129;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043283	112043284	G	GT	112043283	-
NM_001127511.3(APC):c.-131G>A	324	APC	Benign	rs572582235	RCV000525297;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043284	112043284	G	A	NC_000005.9:g.112043284G>A	ClinGen:CA124924960	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-131G>C	324	APC	Likely benign	rs572582235	RCV000542278;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043284	112043284	G	C	NC_000005.9:g.112043284G>C	ClinGen:CA124924962	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-131G>T	324	APC	Benign	rs572582235	RCV000554731;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043284	112043284	G	T	NC_000005.9:g.112043284G>T	ClinGen:CA124924963	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-131_-130insT	324	APC	Uncertain significance	rs1750583446	RCV001299755;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043284	112043285	G	GT	112043284	-
NM_001127511.3(APC):c.-131_-130insC	324	APC	Uncertain significance	-1	RCV001363228;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043284	112043285	G	GC	112043284	-
NM_001127511.3(APC):c.-130G>C	324	APC	Likely benign	rs1056513509	RCV000541367;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043285	112043285	G	C	NC_000005.9:g.112043285G>C	ClinGen:CA124924964	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-130G>T	324	APC	Uncertain significance	rs1056513509	RCV000553831;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043285	112043285	G	T	NC_000005.9:g.112043285G>T	ClinGen:CA124924965	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-130G>A	324	APC	Uncertain significance	rs1056513509	RCV001304288;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043285	112043285	G	A	112043285	-
NM_001127511.3(APC):c.-129G>A	324	APC	Uncertain significance	rs1750583768	RCV001349247;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043286	112043286	G	A	112043286	-
NM_001127511.3(APC):c.-124_-104dup	324	APC	Uncertain significance	-1	RCV001368749;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043286	112043287	G	GGGGACCTGCGGGCTCAGGCCC	112043286	-
NM_001127511.3(APC):c.-128G>C	324	APC	Conflicting interpretations of pathogenicity	rs543098847	RCV000528919\|RCV000764557;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:C1851124,OMIM:135290, Orphanet:873; MONDO:MONDO:0002032,MedGen:C0699790; Human Phenotype Ontology:HP:0001402,Human Phenotype Ontology:HP:0002899,Human Phenotype Ontology:HP:0003007,Human Phenotype Onto	5	112043287	112043287	G	C	5:g.112043287G>C	ClinGen:CA124924970	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-128G>A	324	APC	Uncertain significance	rs543098847	RCV001342220;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043287	112043287	G	A	112043287	-
NM_001127511.3(APC):c.-128G>T	324	APC	Uncertain significance	rs543098847	RCV001348677;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043287	112043287	G	T	112043287	-
NM_001127511.3(APC):c.-128_-127delinsTT	324	APC	Uncertain significance	-1	RCV001931280;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043287	112043288	GG	TT	112043287	-
NM_001127511.3(APC):c.-127G>T	324	APC	Uncertain significance	rs1235543350	RCV000818383;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043288	112043288	G	T	5:g.112043288G>T	-
NM_001127511.3(APC):c.-127G>A	324	APC	Uncertain significance	-1	RCV001971955;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043288	112043288	G	A	112043288	-
NM_001127511.3(APC):c.-127G>C	324	APC	Uncertain significance	-1	RCV001939053;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043288	112043288	G	C	112043288	-
NM_001127511.3(APC):c.-126G>A	324	APC	Uncertain significance	rs948080320	RCV000535873\|RCV001805183;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112043289	112043289	G	A	NC_000005.9:g.112043289G>A	ClinGen:CA124924998	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-126G>T	324	APC	Conflicting interpretations of pathogenicity	rs948080320	RCV000548369\|RCV001183244\|RCV001704678;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202	5	112043289	112043289	G	T	NC_000005.9:g.112043289G>T	ClinGen:CA124925003	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-126dup	324	APC	Benign/Likely benign	rs565045828	RCV000861619\|RCV001547554;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112043289	112043289	C	CG	5:g.112043282_112043283insG	ClinGen:CA124924946	CN169374 not specified;
NM_001127511.3(APC):c.-126G>C	324	APC	Uncertain significance	rs948080320	RCV000646530\|RCV001561386;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112043289	112043289	G	C	5:g.112043289G>C	ClinGen:CA124925002	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-126del	324	APC	Uncertain significance	rs565045828	RCV000807787;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043289	112043289	CG	C	5:g.112043283_112043283del	-
NM_001127511.3(APC):c.-126_-125insT	324	APC	Uncertain significance	rs1750584693	RCV001300520;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043289	112043290	G	GT	112043289	-
NM_001127511.3(APC):c.-125A>T	324	APC	Uncertain significance	rs1045063324	RCV000646651;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043290	112043290	A	T	5:g.112043290A>T	ClinGen:CA124925009	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-125A>C	324	APC	Uncertain significance	rs1045063324	RCV001303581\|RCV001751583;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112043290	112043290	A	C	112043290	-
NM_001127511.3(APC):c.-124C>G	324	APC	Benign	rs964366695	RCV000528009;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043291	112043291	C	G	NC_000005.9:g.112043291C>G	ClinGen:CA658655894	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-124C>T	324	APC	Uncertain significance	rs964366695	RCV000646661;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043291	112043291	C	T	5:g.112043291C>T	ClinGen:CA124925012	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-123C>T	324	APC	Uncertain significance	rs185346146	RCV000646663;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043292	112043292	C	T	NC_000005.9:g.112043292C>T	ClinGen:CA124925015	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-123C>G	324	APC	Uncertain significance	-1	RCV001984128;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043292	112043292	C	G	112043292	-
NM_001127511.3(APC):c.-122T>G	324	APC	Uncertain significance	-1	RCV001910879;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043293	112043293	T	G	112043293	-
NM_001127511.3(APC):c.-121G>C	324	APC	Uncertain significance	rs1173776603	RCV000551717;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043294	112043294	G	C	NC_000005.9:g.112043294G>C	ClinGen:CA658655895	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-120C>T	324	APC	Uncertain significance	rs904073379	RCV000536831;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043295	112043295	C	T	NC_000005.9:g.112043295C>T	ClinGen:CA124925018	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-119G>A	324	APC	Uncertain significance	rs1460028540	RCV000558365;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043296	112043296	G	A	NC_000005.9:g.112043296G>A	ClinGen:CA658655896	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-119G>C	324	APC	Uncertain significance	rs1460028540	RCV000813148;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043296	112043296	G	C	5:g.112043296G>C	-
NM_001127511.3(APC):c.-118G>T	324	APC	Uncertain significance	rs1372371966	RCV000646541;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043297	112043297	G	T	5:g.112043297G>T	ClinGen:CA658796613	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-117_-97del	324	APC	Uncertain significance	rs1433763412	RCV000810346;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043298	112043318	CCTGCGGGCTCAGGCCCGGGAG	C	5:g.112043292_112043312del	-
NM_001127511.3(APC):c.-116C>T	324	APC	Uncertain significance	rs1750586844	RCV001315146;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043299	112043299	C	T	112043299	-
NM_001127511.3(APC):c.-116C>G	324	APC	Uncertain significance	rs1750586844	RCV001342073;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043299	112043299	C	G	112043299	-
NM_001127511.3(APC):c.-115T>C	324	APC	Uncertain significance	rs1580996349	RCV000793940;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043300	112043300	T	C	5:g.112043300T>C	-
NM_001127511.3(APC):c.-114C>G	324	APC	Uncertain significance	rs1452815000	RCV000800259;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043301	112043301	C	G	5:g.112043301C>G	-
NM_001127511.3(APC):c.-114C>A	324	APC	Uncertain significance	rs1452815000	RCV001326051;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043301	112043301	C	A	112043301	-
NM_001127511.3(APC):c.-113A>G	324	APC	Uncertain significance	rs1052992527	RCV000548108;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043302	112043302	A	G	5:g.112043302A>G	ClinGen:CA124925024	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-113A>C	324	APC	Uncertain significance	-1	RCV001368818;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043302	112043302	A	C	112043302	-
NM_001127511.3(APC):c.-112G>A	324	APC	Uncertain significance	rs1750587562	RCV001317414;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043303	112043303	G	A	112043303	-
NM_001127511.3(APC):c.-111G>A	324	APC	Uncertain significance	rs1750587691	RCV001338654;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043304	112043304	G	A	112043304	-
NM_001127511.3(APC):c.-110C>T	324	APC	Uncertain significance	rs1029692674	RCV000646561;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043305	112043305	C	T	5:g.112043305C>T	ClinGen:CA124925027	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-109C>G	324	APC	Benign	rs761634030	RCV000537737;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043306	112043306	C	G	NC_000005.9:g.112043306C>G	ClinGen:CA124925030	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-109C>A	324	APC	Uncertain significance	rs761634030	RCV000804732;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043306	112043306	C	A	5:g.112043306C>A	-
NM_001127511.3(APC):c.-109_-108delinsTG	324	APC	Uncertain significance	rs1750588164	RCV001297588;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043306	112043307	CC	TG	112043306	-
NM_001127511.3(APC):c.-109C>T	324	APC	Uncertain significance	-1	RCV001943010;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043306	112043306	C	T	112043306	-
NM_001127511.3(APC):c.-108C>G	324	APC	Uncertain significance	rs561513597	RCV000559288;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043307	112043307	C	G	NC_000005.9:g.112043307C>G	ClinGen:CA124925037	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-108C>T	324	APC	Uncertain significance	rs561513597	RCV000646599;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043307	112043307	C	T	5:g.112043307C>T	ClinGen:CA658796614	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-108C>A	324	APC	Uncertain significance	rs561513597	RCV000799022;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043307	112043307	C	A	5:g.112043307C>A	-
NM_001127511.3(APC):c.-107G>A	324	APC	Uncertain significance	-1	RCV002009026;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043308	112043308	G	A	112043308	-
NM_001127511.3(APC):c.-105G>C	324	APC	Uncertain significance	rs1337548978	RCV000807170;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043310	112043310	G	C	5:g.112043310G>C	-
NM_001127511.3(APC):c.-105G>A	324	APC	Uncertain significance	-1	RCV001373507;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043310	112043310	G	A	112043310	-
NM_001127511.3(APC):c.-104A>T	324	APC	Uncertain significance	rs909684637	RCV001318275;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043311	112043311	A	T	112043311	-
NM_001127511.3(APC):c.-103G>C	324	APC	Uncertain significance	-1	RCV001372232;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043312	112043312	G	C	112043312	-
NM_001127511.3(APC):c.-102C>T	324	APC	Uncertain significance	-1	RCV001365106;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043313	112043313	C	T	112043313	-
NM_001127511.3(APC):c.-101T>G	324	APC	Uncertain significance	-1	RCV001904287;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043314	112043314	T	G	112043314	-
NM_001127511.3(APC):c.-100G>A	324	APC	Uncertain significance	-1	RCV002026601;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043315	112043315	G	A	112043315	-
NM_001127511.3(APC):c.-98G>A	324	APC	Uncertain significance	rs997256982	RCV000544478;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043317	112043317	G	A	NC_000005.9:g.112043317G>A	ClinGen:CA124925040	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-96A>C	324	APC	Uncertain significance	rs1411710258	RCV000529573;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043319	112043319	A	C	5:g.112043319A>C	ClinGen:CA658655897	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-95C>T	324	APC	Uncertain significance	-1	RCV001901772;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043320	112043320	C	T	112043320	-
NM_001127511.3(APC):c.-95C>G	324	APC	Uncertain significance	-1	RCV002024847;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043320	112043320	C	G	112043320	-
NM_001127511.3(APC):c.-94C>A	324	APC	Uncertain significance	rs1219858068	RCV001296621;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043321	112043321	C	A	112043321	-
NM_001127511.3(APC):c.-94C>T	324	APC	Uncertain significance	-1	RCV001366878;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043321	112043321	C	T	112043321	-
NM_001127511.3(APC):c.-93G>A	324	APC	Uncertain significance	-1	RCV002014115;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043322	112043322	G	A	112043322	-
NM_001127511.3(APC):c.-92A>G	324	APC	Uncertain significance	rs1750589682	RCV001295883;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043323	112043323	A	G	112043323	-
NM_001127511.3(APC):c.-92A>T	324	APC	Uncertain significance	rs1750589682	RCV001302403;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043323	112043323	A	T	112043323	-
NM_001127511.3(APC):c.-91G>C	324	APC	Uncertain significance	rs1400212160	RCV000818339;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043324	112043324	G	C	5:g.112043324G>C	-
NM_001127511.3(APC):c.-91G>A	324	APC	Uncertain significance	-1	RCV001361389;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043324	112043324	G	A	112043324	-
NM_001127511.3(APC):c.-90G>T	324	APC	Uncertain significance	rs1750590013	RCV001300036;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043325	112043325	G	T	112043325	-
NM_001127511.3(APC):c.-90G>A	324	APC	Uncertain significance	rs1750590013	RCV001320645;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043325	112043325	G	A	112043325	-
NM_001127511.3(APC):c.-89T>G	324	APC	Uncertain significance	rs1030112006	RCV001347202;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043326	112043326	T	G	112043326	-
NM_001127511.3(APC):c.-88T>G	324	APC	Uncertain significance	rs531931776	RCV001308460;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043327	112043327	T	G	112043327	-
NM_001127511.3(APC):c.-87G>A	324	APC	Uncertain significance	-1	RCV001359543;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043328	112043328	G	A	112043328	-
NM_001127511.3(APC):c.-86G>C	324	APC	Uncertain significance	rs926522652	RCV000646691;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043329	112043329	G	C	5:g.112043329G>C	ClinGen:CA561890258	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-86G>A	324	APC	Uncertain significance	-1	RCV001363517;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043329	112043329	G	A	112043329	-
NM_001127511.3(APC):c.-85C>T	324	APC	Uncertain significance	rs1750590870	RCV001317680;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043330	112043330	C	T	112043330	-
NM_001127511.3(APC):c.-85C>A	324	APC	Uncertain significance	-1	RCV002005917;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043330	112043330	C	A	112043330	-
NM_001127511.3(APC):c.-84T>C	324	APC	Uncertain significance	rs1340630542	RCV000646611;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043331	112043331	T	C	NC_000005.9:g.112043331T>C	ClinGen:CA561890259	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-83C>A	324	APC	Uncertain significance	rs1306105402	RCV000545384;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043332	112043332	C	A	NC_000005.9:g.112043332C>A	ClinGen:CA658655898	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-83C>T	324	APC	Uncertain significance	rs1306105402	RCV000560201;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043332	112043332	C	T	NC_000005.9:g.112043332C>T	ClinGen:CA561890261	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-83del	324	APC	Likely benign	rs1561393532	RCV000804757;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043332	112043332	TC	T	5:g.112043332_112043332del	-
NM_001127511.3(APC):c.-83C>G	324	APC	Uncertain significance	rs1306105402	RCV000807582;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043332	112043332	C	G	5:g.112043332C>G	-
NM_001127511.3(APC):c.-82G>T	324	APC	Uncertain significance	rs1750591561	RCV001308901;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043333	112043333	G	T	112043333	-
NM_001127511.3(APC):c.-82G>A	324	APC	Uncertain significance	rs1750591561	RCV001347553;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043333	112043333	G	A	112043333	-
NM_001127511.3(APC):c.-81A>G	324	APC	Uncertain significance	rs1395227226	RCV001294381;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043334	112043334	A	G	112043334	-
NM_001127511.3(APC):c.-79G>A	324	APC	Uncertain significance	rs1369181601	RCV000530496;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043336	112043336	G	A	NC_000005.9:g.112043336G>A	ClinGen:CA561890262	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-79G>T	324	APC	Uncertain significance	rs1369181601	RCV001300865;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043336	112043336	G	T	112043336	-
NM_001127511.3(APC):c.-78C>T	324	APC	Likely benign	rs953008592	RCV000552073;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043337	112043337	C	T	5:g.112043337C>T	ClinGen:CA124925056	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-78C>G	324	APC	Uncertain significance	rs953008592	RCV001349602;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043337	112043337	C	G	112043337	-
NM_001127511.3(APC):c.-77T>C	324	APC	Uncertain significance	-1	RCV001372301;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043338	112043338	T	C	112043338	-
NM_001127511.3(APC):c.-76G>T	324	APC	Uncertain significance	rs1750592062	RCV001348932;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043339	112043339	G	T	112043339	-
NM_001127511.3(APC):c.-74T>C	324	APC	Uncertain significance	rs1554060234	RCV000541706;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043341	112043341	T	C	5:g.112043341T>C	ClinGen:CA658655899	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-73C>G	324	APC	Uncertain significance	rs1415610352	RCV000531395;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043342	112043342	C	G	NC_000005.9:g.112043342C>G	ClinGen:CA658655900	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-71del	324	APC	Uncertain significance	rs1750592547	RCV001347736;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043342	112043342	TC	T	112043341	-
NM_001127511.3(APC):c.-72C>A	324	APC	Uncertain significance	-1	RCV001363372;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043343	112043343	C	A	112043343	-
NM_001127511.3(APC):c.-71C>T	324	APC	Uncertain significance	rs544132569	RCV000552986;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043344	112043344	C	T	5:g.112043344C>T	ClinGen:CA124925059	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-70A>C	324	APC	Uncertain significance	rs1580996503	RCV000823709;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043345	112043345	A	C	5:g.112043345A>C	-
NM_001127511.3(APC):c.-70A>G	324	APC	Uncertain significance	-1	RCV001372522;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043345	112043345	A	G	112043345	-
NM_001127511.3(APC):c.-69G>C	324	APC	Uncertain significance	-1	RCV001945727;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043346	112043346	G	C	112043346	-
NM_001127511.3(APC):c.-69G>A	324	APC	Uncertain significance	-1	RCV002015926;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043346	112043346	G	A	112043346	-
NM_001127511.3(APC):c.-68G>A	324	APC	Uncertain significance	rs1163893701	RCV000542632;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043347	112043347	G	A	5:g.112043347G>A	ClinGen:CA658655901	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-68G>C	324	APC	Uncertain significance	rs1163893701	RCV000794432;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043347	112043347	G	C	5:g.112043347G>C	-
NM_001127511.3(APC):c.-65C>T	324	APC	Uncertain significance	rs1473007055	RCV000527765;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043350	112043350	C	T	NC_000005.9:g.112043350C>T	ClinGen:CA658655902	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-65_-64del	324	APC	Uncertain significance	rs1580996531	RCV000801098;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043350	112043351	ACT	A	5:g.112043350_112043351del	-
NM_001127511.3(APC):c.-64T>C	324	APC	Uncertain significance	rs1554060239	RCV000549372;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043351	112043351	T	C	NC_000005.9:g.112043351T>C	ClinGen:CA658655903	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-62TTG[1]	324	APC	Uncertain significance	rs1750593628	RCV001304629;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043351	112043353	CTGT	C	112043350	-
NM_001127511.3(APC):c.-63G>A	324	APC	Uncertain significance	rs1369215546	RCV001300279;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043352	112043352	G	A	112043352	-
NM_001127511.3(APC):c.-63G>C	324	APC	Uncertain significance	-1	RCV001362239;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043352	112043352	G	C	112043352	-
NM_001127511.3(APC):c.-61T>C	324	APC	Uncertain significance	rs1554060241	RCV000646610;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043354	112043354	T	C	NC_000005.9:g.112043354T>C	ClinGen:CA658796615	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-61T>A	324	APC	Uncertain significance	-1	RCV002041983;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043354	112043354	T	A	112043354	-
NM_001127511.3(APC):c.-60G>A	324	APC	Uncertain significance	rs1580996554	RCV000794015;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043355	112043355	G	A	5:g.112043355G>A	-
NM_001127511.3(APC):c.-60G>C	324	APC	Uncertain significance	-1	RCV001359942;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043355	112043355	G	C	112043355	-
NM_001127511.3(APC):c.-59T>C	324	APC	Uncertain significance	rs1554060243	RCV000646593;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043356	112043356	T	C	5:g.112043356T>C	ClinGen:CA658796616	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-59T>A	324	APC	Uncertain significance	rs1554060243	RCV001304436;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043356	112043356	T	A	112043356	-
NM_001127511.3(APC):c.-56_-47dup	324	APC	Uncertain significance	rs1750594271	RCV001307715;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043356	112043357	T	TTGGCTGTTGG	112043356	-
NM_001127511.3(APC):c.-58T>C	324	APC	Uncertain significance	-1	RCV002001173;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043357	112043357	T	C	112043357	-
NM_001127511.3(APC):c.-57G>A	324	APC	Uncertain significance	rs1580996569	RCV000810825;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043358	112043358	G	A	5:g.112043358G>A	-
NM_001127511.3(APC):c.-56G>C	324	APC	Uncertain significance	-1	RCV001359222;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043359	112043359	G	C	112043359	-
NM_001127511.3(APC):c.-55C>T	324	APC	Likely benign	rs1189950358	RCV000538998;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043360	112043360	C	T	NC_000005.9:g.112043360C>T	ClinGen:CA658655904	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-53G>A	324	APC	Uncertain significance	rs1750595145	RCV001326446;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043362	112043362	G	A	112043362	-
NM_001127511.3(APC):c.-50G>C	324	APC	Uncertain significance	rs778974265	RCV001312951;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043365	112043365	G	C	112043365	-
NM_001127511.3(APC):c.-47G>A	324	APC	Uncertain significance	rs1750595339	RCV001305396;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043368	112043368	G	A	112043368	-
NM_001127511.3(APC):c.-46A>G	324	APC	Uncertain significance	rs1750595463	RCV001307591;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043369	112043369	A	G	112043369	-
NM_001127511.3(APC):c.-44G>A	324	APC	Uncertain significance	rs1162218041	RCV001337953;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043371	112043371	G	A	112043371	-
NM_001127511.3(APC):c.-41G>T	324	APC	Likely benign	rs748454058	RCV000528691;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043374	112043374	G	T	5:g.112043374G>T	ClinGen:CA058285	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-41G>A	324	APC	Uncertain significance	-1	RCV001365080;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043374	112043374	G	A	112043374	-
NM_001127511.3(APC):c.-41G>C	324	APC	Uncertain significance	-1	RCV001970789;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043374	112043374	G	C	112043374	-
NM_001127511.3(APC):c.-40G>A	324	APC	Uncertain significance	rs1750595782	RCV001299226;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043375	112043375	G	A	112043375	-
NM_001127511.3(APC):c.-39T>A	324	APC	Uncertain significance	rs1466692709	RCV000646667;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043376	112043376	T	A	NC_000005.9:g.112043376T>A	ClinGen:CA561890264	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-39T>C	324	APC	Uncertain significance	rs1466692709	RCV001349272;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043376	112043376	T	C	112043376	-
NM_001127511.3(APC):c.-36dup	324	APC	Uncertain significance	-1	RCV001945110;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043377	112043378	G	GA	112043377	-
NM_001127511.3(APC):c.-36A>G	324	APC	Uncertain significance	-1	RCV001371997;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043379	112043379	A	G	112043379	-
NM_001127511.3(APC):c.-35G>C	324	APC	Uncertain significance	-1	RCV001371765;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043380	112043380	G	C	112043380	-
NM_001127511.3(APC):c.-34C>T	324	APC	Uncertain significance	rs1376128351	RCV000550248;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043381	112043381	C	T	5:g.112043381C>T	ClinGen:CA561890266	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-33A>T	324	APC	Uncertain significance	rs758576717	RCV001344900;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043382	112043382	A	T	112043382	-
NM_001127511.3(APC):c.-32C>T	324	APC	Uncertain significance	rs1015952631	RCV000646660;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043383	112043383	C	T	NC_000005.9:g.112043383C>T	ClinGen:CA124925068	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-32del	324	APC	Uncertain significance	rs1750596841	RCV001303567;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043383	112043383	AC	A	112043382	-
NM_001127511.3(APC):c.-31T>G	324	APC	Benign	rs78429131	RCV000507288\|RCV001512459\|RCV001712464;	N	MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112043384	112043384	T	G	5:g.112043384T>G	ClinGen:CA057801	CN169374 not specified;
NM_001127511.3(APC):c.-29_-24dup	324	APC	Uncertain significance	-1	RCV001875470;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043384	112043385	T	TCAGTTG	112043384	-
NM_001127511.3(APC):c.-31T>C	324	APC	Uncertain significance	-1	RCV001996804;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043384	112043384	T	C	112043384	-
NM_001127511.3(APC):c.-29A>G	324	APC	Uncertain significance	rs1750597287	RCV001350726;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043386	112043386	A	G	112043386	-
NM_001127511.3(APC):c.-28G>A	324	APC	Uncertain significance	rs1580996638	RCV000801587;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043387	112043387	G	A	5:g.112043387G>A	-
NM_001127511.3(APC):c.-28G>T	324	APC	Uncertain significance	rs1580996638	RCV001297784;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043387	112043387	G	T	112043387	-
NM_001127511.3(APC):c.-25G>A	324	APC	Uncertain significance	-1	RCV001918589;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043390	112043390	G	A	112043390	-
NM_001127511.3(APC):c.-22T>G	324	APC	Uncertain significance	rs765199134	RCV000808549;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043393	112043393	T	G	5:g.112043393T>G	-
NM_001127511.3(APC):c.-21T>G	324	APC	Uncertain significance	rs1750597924	RCV001299510;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043394	112043394	T	G	112043394	-
NM_001127511.3(APC):c.-20C>A	324	APC	Uncertain significance	-1	RCV001988817;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043395	112043395	C	A	112043395	-
NM_001127511.3(APC):c.-18C>G	324	APC	Uncertain significance	rs1357561329	RCV000646640;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043397	112043397	C	G	5:g.112043397C>G	ClinGen:CA658796617	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-18C>A	324	APC	Uncertain significance	rs1357561329	RCV000698295;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043397	112043397	C	A	5:g.112043397C>A	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-18C>T	324	APC	Uncertain significance	-1	RCV002045681;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043397	112043397	C	T	112043397	-
NM_001127511.3(APC):c.-17G>C	324	APC	Uncertain significance	rs1750598442	RCV001342526;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043398	112043398	G	C	112043398	-
NM_001127511.3(APC):c.-14C>T	324	APC	Uncertain significance	rs1554060248	RCV000662369;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043401	112043401	C	T	5:g.112043401C>T	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-13C>G	324	APC	Uncertain significance	rs1257473862	RCV001339984;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043402	112043402	C	G	112043402	-
NM_001127511.3(APC):c.-13C>T	324	APC	Uncertain significance	rs1257473862	RCV001345625;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043402	112043402	C	T	112043402	-
NM_001127511.3(APC):c.-12T>C	324	APC	Uncertain significance	rs1057517554	RCV000409373;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043403	112043403	T	C	5:g.112043403T>C	ClinGen:CA16042075	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-11C>G	324	APC	Uncertain significance	rs1750599043	RCV001313538;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043404	112043404	C	G	112043404	-
NM_001127511.3(APC):c.-11C>T	324	APC	Uncertain significance	rs1750599043	RCV001322123;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043404	112043404	C	T	112043404	-
NM_001127511.3(APC):c.-10G>T	324	APC	Uncertain significance	rs1184095408	RCV001352064;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043405	112043405	G	T	112043405	-
NM_001127511.3(APC):c.-10G>A	324	APC	Uncertain significance	-1	RCV001360857;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043405	112043405	G	A	112043405	-
NM_001127511.3(APC):c.-9G>A	324	APC	Uncertain significance	-1	RCV002027795;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043406	112043406	G	A	112043406	-
NM_001127511.3(APC):c.-8C>G	324	APC	Uncertain significance	rs1750599549	RCV001318053;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043407	112043407	C	G	112043407	-
NM_001127511.3(APC):c.-8C>T	324	APC	Uncertain significance	rs1750599549	RCV001324238;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043407	112043407	C	T	112043407	-
NM_001127511.3(APC):c.-7_-6delinsAA	324	APC	Uncertain significance	rs1750599736	RCV001307254;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043408	112043409	GC	AA	112043408	-
NM_001127511.3(APC):c.-7G>A	324	APC	Uncertain significance	-1	RCV002042108;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043408	112043408	G	A	112043408	-
NM_001127511.3(APC):c.-2del	324	APC	Uncertain significance	rs1257317812	RCV001303681;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043409	112043409	GC	G	112043408	-
NM_001127511.3(APC):c.-5C>T	324	APC	Uncertain significance	rs972010514	RCV000646533;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043410	112043410	C	T	5:g.112043410C>T	ClinGen:CA124925090	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-5C>A	324	APC	Uncertain significance	rs972010514	RCV000662776\|RCV001855406;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043410	112043410	C	A	5:g.112043410C>A	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-4C>G	324	APC	Uncertain significance	rs1750600295	RCV001312824;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043411	112043411	C	G	112043411	-
NM_001127511.3(APC):c.-3C>A	324	APC	Conflicting interpretations of pathogenicity	rs771410311	RCV000679420\|RCV001308695;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043412	112043412	C	A	5:g.112043412C>A	-	CN517202 not provided;
NM_001127511.3(APC):c.-3C>G	324	APC	Uncertain significance	-1	RCV001362143;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043412	112043412	C	G	112043412	-
NM_001127511.3(APC):c.-3C>T	324	APC	Uncertain significance	-1	RCV002042922;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043412	112043412	C	T	112043412	-
NM_001127511.3(APC):c.-2C>T	324	APC	Uncertain significance	rs1395970563	RCV000556891;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043413	112043413	C	T	NC_000005.9:g.112043413C>T	ClinGen:CA561890274	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.-1T>A	324	APC	Uncertain significance	rs1750600817	RCV001313214;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043414	112043414	T	A	112043414	-
NM_001127511.3(APC):c.-1T>C	324	APC	Uncertain significance	rs1750600817	RCV001348826;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043414	112043414	T	C	112043414	-
NM_001127511.3(APC):c.-1T>G	324	APC	Uncertain significance	rs1750600817	RCV001351327;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043414	112043414	T	G	112043414	-
NM_001127511.3(APC):c.1A>G (p.Met1Val)	324	APC	Uncertain significance	rs189807660	RCV000551159\|RCV000764558\|RCV001092762;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:C1851124,OMIM:135290, Orphanet:873; MONDO:MONDO:0002032,MedGen:C0699790; Human Phenotype Ontology:HP:0001402,Human Phenotype Ontology:HP:0002899,Human Phenotype Ontology:HP:0003007,Human Phenotype Onto	5	112043415	112043415	A	G	5:g.112043415A>G	ClinGen:CA124925094	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.1A>T (p.Met1Leu)	324	APC	Uncertain significance	rs189807660	RCV000662980;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043415	112043415	A	T	5:g.112043415A>T	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.2T>C (p.Met1Thr)	324	APC	Uncertain significance	-1	RCV001365459;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043416	112043416	T	C	112043416	-
NM_001127511.3(APC):c.3G>A (p.Met1Ile)	324	APC	Uncertain significance	rs1057517567	RCV000411262;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043417	112043417	G	A	NC_000005.9:g.112043417G>A	ClinGen:CA16042076	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.7G>A (p.Ala3Thr)	324	APC	Uncertain significance	rs1170818329	RCV001321219;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043421	112043421	G	A	112043421	-
NM_001127511.3(APC):c.9C>T (p.Ala3=)	324	APC	Uncertain significance	rs1750602563	RCV001307338;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043423	112043423	C	T	112043423	-
NM_001127511.3(APC):c.10T>C (p.Ser4Pro)	324	APC	Uncertain significance	rs959934876	RCV001300753;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043424	112043424	T	C	112043424	-
NM_001127511.3(APC):c.10T>A (p.Ser4Thr)	324	APC	Uncertain significance	-1	RCV001373776;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043424	112043424	T	A	112043424	-
NM_001127511.3(APC):c.12C>T (p.Ser4=)	324	APC	Uncertain significance	rs1554060261	RCV000646609;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043426	112043426	C	T	5:g.112043426C>T	ClinGen:CA658796618	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.13C>G (p.Leu5Val)	324	APC	Uncertain significance	-1	RCV002025542;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043427	112043427	C	G	112043427	-
NM_001127511.3(APC):c.16G>A (p.Gly6Ser)	324	APC	Conflicting interpretations of pathogenicity	rs1043505718	RCV000679422\|RCV001079538;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043430	112043430	G	A	NC_000005.9:g.112043430G>A	ClinGen:CA124925107	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.17G>A (p.Gly6Asp)	324	APC	Uncertain significance	rs1304453341	RCV000646592;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043431	112043431	G	A	5:g.112043431G>A	ClinGen:CA360611615	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.18C>T (p.Gly6=)	324	APC	Uncertain significance	-1	RCV002025525;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043432	112043432	C	T	112043432	-
NM_001127511.3(APC):c.20C>T (p.Ser7Leu)	324	APC	Uncertain significance	rs1402688776	RCV001295744;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043434	112043434	C	T	112043434	-
NM_001127511.3(APC):c.22G>A (p.Gly8Ser)	324	APC	Likely benign	rs777188684	RCV000646529;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043436	112043436	G	A	5:g.112043436G>A	ClinGen:CA056309	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.23G>A (p.Gly8Asp)	324	APC	Uncertain significance	-1	RCV001989696;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043437	112043437	G	A	112043437	-
NM_001127511.3(APC):c.25C>A (p.Pro9Thr)	324	APC	Uncertain significance	rs1291188034	RCV000646633;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043439	112043439	C	A	NC_000005.9:g.112043439C>A	ClinGen:CA360611647	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.25C>T (p.Pro9Ser)	324	APC	Uncertain significance	rs1291188034	RCV001298883;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043439	112043439	C	T	112043439	-
NM_001127511.3(APC):c.25C>G (p.Pro9Ala)	324	APC	Uncertain significance	-1	RCV001368330;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043439	112043439	C	G	112043439	-
NM_001127511.3(APC):c.26C>A (p.Pro9Gln)	324	APC	Uncertain significance	rs1342657032	RCV001340890;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043440	112043440	C	A	112043440	-
NM_001127511.3(APC):c.27G>C (p.Pro9=)	324	APC	Uncertain significance	rs761592349	RCV000820364;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043441	112043441	G	C	5:g.112043441G>C	-
NM_001127511.3(APC):c.27G>A (p.Pro9=)	324	APC	Uncertain significance	-1	RCV001889832;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043441	112043441	G	A	112043441	-
NM_001127511.3(APC):c.28G>T (p.Val10Phe)	324	APC	Uncertain significance	rs1397116635	RCV000646627;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043442	112043442	G	T	NC_000005.9:g.112043442G>T	ClinGen:CA360611672	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.30C>A (p.Val10=)	324	APC	Likely benign	rs917976853	RCV000557808;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043444	112043444	C	A	NC_000005.9:g.112043444C>A	ClinGen:CA124925115	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.30C>T (p.Val10=)	324	APC	Uncertain significance	rs917976853	RCV001343440;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043444	112043444	C	T	112043444	-
NM_001127511.3(APC):c.31G>A (p.Ala11Thr)	324	APC	Uncertain significance	rs1750604515	RCV001314308;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043445	112043445	G	A	112043445	-
NM_001127511.3(APC):c.35dup (p.Leu13fs)	324	APC	Uncertain significance	rs1750604836	RCV001320124;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043445	112043446	G	GC	112043445	-
NM_001127511.3(APC):c.32C>A (p.Ala11Asp)	324	APC	Uncertain significance	-1	RCV001359328;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043446	112043446	C	A	112043446	-
NM_001127511.3(APC):c.32C>T (p.Ala11Val)	324	APC	Uncertain significance	-1	RCV001360638;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043446	112043446	C	T	112043446	-
NM_001127511.3(APC):c.32C>G (p.Ala11Gly)	324	APC	Uncertain significance	-1	RCV002028779;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043446	112043446	C	G	112043446	-
NM_001127511.3(APC):c.33C>G (p.Ala11=)	324	APC	Uncertain significance	rs1750604976	RCV001302917;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043447	112043447	C	G	112043447	-
NM_001127511.3(APC):c.34C>T (p.Pro12Ser)	324	APC	Uncertain significance	rs1316080865	RCV000813925;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043448	112043448	C	T	5:g.112043448C>T	-
NM_001127511.3(APC):c.36T>C (p.Pro12=)	324	APC	Uncertain significance	-1	RCV001988028;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043450	112043450	T	C	112043450	-
NM_001127511.3(APC):c.40_49del (p.Pro14fs)	324	APC	Uncertain significance	-1	RCV001361077;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043452	112043461	TTGCCCGCTTC	T	112043451	-
NM_001127511.3(APC):c.39G>C (p.Leu13Phe)	324	APC	Uncertain significance	rs772953367	RCV000542972;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043453	112043453	G	C	NC_000005.9:g.112043453G>C	ClinGen:CA124925119	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.39G>A (p.Leu13=)	324	APC	Uncertain significance	rs772953367	RCV000646647;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043453	112043453	G	A	NC_000005.9:g.112043453G>A	ClinGen:CA650199572	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.39G>T (p.Leu13Phe)	324	APC	Uncertain significance	rs772953367	RCV000799480;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043453	112043453	G	T	5:g.112043453G>T	-
NM_001127511.3(APC):c.40C>T (p.Pro14Ser)	324	APC	Uncertain significance	rs1750605530	RCV001345066;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043454	112043454	C	T	112043454	-
NM_001127511.3(APC):c.41C>T (p.Pro14Leu)	324	APC	Uncertain significance	-1	RCV001366084;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043455	112043455	C	T	112043455	-
NM_001127511.3(APC):c.42C>T (p.Pro14=)	324	APC	Uncertain significance	-1	RCV001366379;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043456	112043456	C	T	112043456	-
NM_001127511.3(APC):c.42C>G (p.Pro14=)	324	APC	Uncertain significance	-1	RCV001894914;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043456	112043456	C	G	112043456	-
NM_001127511.3(APC):c.45T>C (p.Ala15=)	324	APC	Uncertain significance	-1	RCV002006552;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043459	112043459	T	C	112043459	-
NM_001127511.3(APC):c.46T>C (p.Ser16Pro)	324	APC	Uncertain significance	rs1554060278	RCV000532648;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043460	112043460	T	C	NC_000005.9:g.112043460T>C	ClinGen:CA360611747	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.46T>G (p.Ser16Ala)	324	APC	Uncertain significance	rs1554060278	RCV001347246;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043460	112043460	T	G	112043460	-
NM_001127511.3(APC):c.47C>G (p.Ser16Cys)	324	APC	Uncertain significance	-1	RCV002004660;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043461	112043461	C	G	112043461	-
NM_001127511.3(APC):c.47C>A (p.Ser16Tyr)	324	APC	Uncertain significance	-1	RCV001968713;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043461	112043461	C	A	112043461	-
NM_001127511.3(APC):c.48T>C (p.Ser16=)	324	APC	Likely benign	rs980704771	RCV000409172;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043462	112043462	T	C	NC_000005.9:g.112043462T>C	ClinGen:CA16042077	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.48T>G (p.Ser16=)	324	APC	Uncertain significance	rs980704771	RCV000558748;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043462	112043462	T	G	5:g.112043462T>G	ClinGen:CA124925134	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.49G>A (p.Val17Ile)	324	APC	Uncertain significance	rs1750606571	RCV001296677;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043463	112043463	G	A	112043463	-
NM_001127511.3(APC):c.52C>G (p.Pro18Ala)	324	APC	Uncertain significance	-1	RCV001915419;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043466	112043466	C	G	112043466	-
NM_001127511.3(APC):c.53C>T (p.Pro18Leu)	324	APC	Uncertain significance	rs1265754890	RCV000799808;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043467	112043467	C	T	5:g.112043467C>T	-
NM_001127511.3(APC):c.53C>G (p.Pro18Arg)	324	APC	Uncertain significance	rs1265754890	RCV001321460;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043467	112043467	C	G	112043467	-
NM_001127511.3(APC):c.57dup (p.Ser20fs)	324	APC	Uncertain significance	-1	RCV001364603;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043468	112043469	A	AC	112043468	-
NM_001127511.3(APC):c.55C>T (p.Pro19Ser)	324	APC	Uncertain significance	-1	RCV002009293;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043469	112043469	C	T	112043469	-
NM_001127511.3(APC):c.56C>T (p.Pro19Leu)	324	APC	Uncertain significance	rs1349659337	RCV000805483;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043470	112043470	C	T	5:g.112043470C>T	-
NM_001127511.3(APC):c.57C>T (p.Pro19=)	324	APC	Uncertain significance	-1	RCV001365700;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043471	112043471	C	T	112043471	-
NM_001127511.3(APC):c.59C>G (p.Ser20Ter)	324	APC	Uncertain significance	-1	RCV001363958;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043473	112043473	C	G	112043473	-
NM_001127511.3(APC):c.60A>T (p.Ser20=)	324	APC	Uncertain significance	-1	RCV001908601;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043474	112043474	A	T	112043474	-
NM_001127511.3(APC):c.61G>T (p.Val21Phe)	324	APC	Uncertain significance	rs1750607281	RCV001318783;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043475	112043475	G	T	112043475	-
NM_001127511.3(APC):c.61G>C (p.Val21Leu)	324	APC	Uncertain significance	-1	RCV001917991;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043475	112043475	G	C	112043475	-
NM_001127511.3(APC):c.63T>G (p.Val21=)	324	APC	Uncertain significance	-1	RCV001363036;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043477	112043477	T	G	112043477	-
NM_001127511.3(APC):c.64C>T (p.Leu22Phe)	324	APC	Uncertain significance	rs1554060282	RCV000533593;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043478	112043478	C	T	5:g.112043478C>T	ClinGen:CA360611829	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.64C>G (p.Leu22Val)	324	APC	Uncertain significance	-1	RCV001890980;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043478	112043478	C	G	112043478	-
NM_001127511.3(APC):c.65T>C (p.Leu22Pro)	324	APC	Uncertain significance	rs1750607611	RCV001345013;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043479	112043479	T	C	112043479	-
NM_001127511.3(APC):c.66C>T (p.Leu22=)	324	APC	Uncertain significance	rs1422300065	RCV000646639;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043480	112043480	C	T	5:g.112043480C>T	ClinGen:CA561890281	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.66C>A (p.Leu22=)	324	APC	Uncertain significance	rs1422300065	RCV001313917;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043480	112043480	C	A	112043480	-
NM_001127511.3(APC):c.67G>A (p.Gly23Arg)	324	APC	Uncertain significance	rs762748481	RCV000555150;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043481	112043481	G	A	NC_000005.9:g.112043481G>A	ClinGen:CA124925142	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.67G>C (p.Gly23Arg)	324	APC	Uncertain significance	-1	RCV001899561;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043481	112043481	G	C	112043481	-
NM_001127511.3(APC):c.69G>T (p.Gly23=)	324	APC	Likely benign	-1	RCV001414825;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043483	112043483	G	T	112043483	-
NM_001127511.3(APC):c.71C>T (p.Ser24Phe)	324	APC	Conflicting interpretations of pathogenicity	rs770241997	RCV000410042;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043485	112043485	C	T	NC_000005.9:g.112043485C>T	ClinGen:CA059369	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.71C>G (p.Ser24Cys)	324	APC	Uncertain significance	rs770241997	RCV000802312;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043485	112043485	C	G	5:g.112043485C>G	-
NM_001127511.3(APC):c.73T>G (p.Trp25Gly)	324	APC	Uncertain significance	-1	RCV002026809;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043487	112043487	T	G	112043487	-
NM_001127511.3(APC):c.74G>A (p.Trp25Ter)	324	APC	Uncertain significance	rs1554060285	RCV000529960;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043488	112043488	G	A	5:g.112043488G>A	ClinGen:CA360611862	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.74G>C (p.Trp25Ser)	324	APC	Uncertain significance	-1	RCV001983990;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043488	112043488	G	C	112043488	-
NM_001127511.3(APC):c.77G>T (p.Ser26Ile)	324	APC	Uncertain significance	rs775738268	RCV000805826\|RCV001766678;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0005575,MedGen:C0346629,OMIM:114500	5	112043491	112043491	G	T	5:g.112043491G>T	-
NM_001127511.3(APC):c.77G>A (p.Ser26Asn)	324	APC	Uncertain significance	rs775738268	RCV001307154;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043491	112043491	G	A	112043491	-
NM_001127511.3(APC):c.78C>A (p.Ser26Arg)	324	APC	Benign	rs113782655	RCV000120009\|RCV000123676\|RCV000238598\|RCV000410035;	N	MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021055,MedGen:C0032580,OMIM:PS175100, Orphanet:733\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043492	112043492	C	A	5:g.112043492C>A	ClinGen:CA025425	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.78C>T (p.Ser26=)	324	APC	Uncertain significance	rs113782655	RCV001319105;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043492	112043492	C	T	112043492	-
NM_001127511.3(APC):c.78C>G (p.Ser26Arg)	324	APC	Uncertain significance	-1	RCV001364958;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043492	112043492	C	G	112043492	-
NM_001127511.3(APC):c.80C>T (p.Thr27Ile)	324	APC	Uncertain significance	rs1400852847	RCV000541191;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043494	112043494	C	T	NC_000005.9:g.112043494C>T	ClinGen:CA360611897	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.80C>G (p.Thr27Ser)	324	APC	Uncertain significance	rs1400852847	RCV001315192;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043494	112043494	C	G	112043494	-
NM_001127511.3(APC):c.82G>C (p.Gly28Arg)	324	APC	Uncertain significance	rs1297745273	RCV001318655;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043496	112043496	G	C	112043496	-
NM_001127511.3(APC):c.82G>A (p.Gly28Ser)	324	APC	Uncertain significance	rs1297745273	RCV001342926;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043496	112043496	G	A	112043496	-
NM_001127511.3(APC):c.83G>A (p.Gly28Asp)	324	APC	Uncertain significance	rs1057517606	RCV000409724;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043497	112043497	G	A	NC_000005.9:g.112043497G>A	ClinGen:CA16042078	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.84C>A (p.Gly28=)	324	APC	Uncertain significance	rs1750609849	RCV001302104;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043498	112043498	C	A	112043498	-
NM_001127511.3(APC):c.85G>T (p.Gly29Cys)	324	APC	Uncertain significance	rs1580996980	RCV000804524;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043499	112043499	G	T	5:g.112043499G>T	-
NM_001127511.3(APC):c.85G>A (p.Gly29Ser)	324	APC	Uncertain significance	-1	RCV001361199;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043499	112043499	G	A	112043499	-
NM_001127511.3(APC):c.86G>A (p.Gly29Asp)	324	APC	Uncertain significance	rs1337289014	RCV000526272;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043500	112043500	G	A	5:g.112043500G>A	ClinGen:CA360611917	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.87C>T (p.Gly29=)	324	APC	Uncertain significance	rs1750610368	RCV001317755;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043501	112043501	C	T	112043501	-
NM_001127511.3(APC):c.88A>T (p.Ser30Cys)	324	APC	Uncertain significance	-1	RCV002004278;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043502	112043502	A	T	112043502	-
NM_001127511.3(APC):c.90C>T (p.Ser30=)	324	APC	Uncertain significance	-1	RCV001360332;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043504	112043504	C	T	112043504	-
NM_001127511.3(APC):c.91A>C (p.Arg31=)	324	APC	Uncertain significance	rs1302045127	RCV000646558;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043505	112043505	A	C	5:g.112043505A>C	ClinGen:CA561890291	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.92G>A (p.Arg31Lys)	324	APC	Uncertain significance	rs1750610701	RCV001297134;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043506	112043506	G	A	112043506	-
NM_001127511.3(APC):c.93G>T (p.Arg31Ser)	324	APC	Uncertain significance	-1	RCV001972922;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043507	112043507	G	T	112043507	-
NM_001127511.3(APC):c.96C>G (p.Ser32Arg)	324	APC	Uncertain significance	rs1446044641	RCV001307352;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043510	112043510	C	G	112043510	-
NM_001127511.3(APC):c.97_112del (p.Cys33fs)	324	APC	Uncertain significance	-1	RCV001362821;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043511	112043526	CTGCGTCCGGCAGGAGA	C	112043510	-
NM_001127511.3(APC):c.98_99delinsTT (p.Cys33Phe)	324	APC	Uncertain significance	rs1750611037	RCV001324127;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043512	112043513	GC	TT	112043512	-
NM_001127511.3(APC):c.99C>T (p.Cys33=)	324	APC	Uncertain significance	rs1312161630	RCV000646563;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043513	112043513	C	T	5:g.112043513C>T	ClinGen:CA561890293	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.100G>A (p.Val34Ile)	324	APC	Uncertain significance	rs1232734822	RCV000646556;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043514	112043514	G	A	NC_000005.9:g.112043514G>A	ClinGen:CA360611986	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.100_101del (p.Val34fs)	324	APC	Uncertain significance	rs1750611348	RCV001342562;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043514	112043515	CGT	C	112043513	-
NM_001127511.3(APC):c.100G>T (p.Val34Phe)	324	APC	Uncertain significance	-1	RCV002010435;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043514	112043514	G	T	112043514	-
NM_001127511.3(APC):c.102C>T (p.Val34=)	324	APC	Uncertain significance	rs763659488	RCV001305362;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043516	112043516	C	T	112043516	-
NM_001127511.3(APC):c.102C>G (p.Val34=)	324	APC	Uncertain significance	rs763659488	RCV001348304;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043516	112043516	C	G	112043516	-
NM_001127511.3(APC):c.103C>T (p.Arg35Trp)	324	APC	Uncertain significance	rs1554060293	RCV000646590;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043517	112043517	C	T	5:g.112043517C>T	ClinGen:CA360611991	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.103C>G (p.Arg35Gly)	324	APC	Uncertain significance	rs1554060293	RCV001320476;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043517	112043517	C	G	112043517	-
NM_001127511.3(APC):c.104G>T (p.Arg35Leu)	324	APC	Uncertain significance	-1	RCV001925304;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043518	112043518	G	T	112043518	-
NM_001127511.3(APC):c.104G>C (p.Arg35Pro)	324	APC	Uncertain significance	-1	RCV002040349;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043518	112043518	G	C	112043518	-
NM_001127511.3(APC):c.106C>A (p.Gln36Lys)	324	APC	Uncertain significance	rs773941688	RCV001352607;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043520	112043520	C	A	112043520	-
NM_001127511.3(APC):c.106C>T (p.Gln36Ter)	324	APC	Uncertain significance	-1	RCV001897387;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043520	112043520	C	T	112043520	-
NM_001127511.3(APC):c.107A>G (p.Gln36Arg)	324	APC	Uncertain significance	rs1580997050	RCV000815945;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043521	112043521	A	G	5:g.112043521A>G	-
NM_001127511.3(APC):c.109G>A (p.Glu37Lys)	324	APC	Uncertain significance	-1	RCV001366905;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043523	112043523	G	A	112043523	-
NM_001127511.3(APC):c.113C>T (p.Thr38Met)	324	APC	Uncertain significance	rs1484678720	RCV000803846;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043527	112043527	C	T	5:g.112043527C>T	-
NM_001127511.3(APC):c.114G>A (p.Thr38=)	324	APC	Uncertain significance	rs761467156	RCV000547842;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043528	112043528	G	A	NC_000005.9:g.112043528G>A	ClinGen:CA561890299	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.114G>C (p.Thr38=)	324	APC	Uncertain significance	rs761467156	RCV001298123;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043528	112043528	G	C	112043528	-
NM_001127511.3(APC):c.114G>T (p.Thr38=)	324	APC	Uncertain significance	-1	RCV001368273;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043528	112043528	G	T	112043528	-
NM_001127511.3(APC):c.116A>G (p.Lys39Arg)	324	APC	Uncertain significance	rs1750612690	RCV001306059;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043530	112043530	A	G	112043530	-
NM_001127511.3(APC):c.117G>C (p.Lys39Asn)	324	APC	Uncertain significance	rs1750612789	RCV001322125;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043531	112043531	G	C	112043531	-
NM_001127511.3(APC):c.118A>T (p.Ser40Cys)	324	APC	Uncertain significance	-1	RCV001365647;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043532	112043532	A	T	112043532	-
NM_001127511.3(APC):c.119G>C (p.Ser40Thr)	324	APC	Conflicting interpretations of pathogenicity	rs587778028	RCV000120010\|RCV000542057\|RCV001705881;	N	MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112043533	112043533	G	C	5:g.112043533G>C	ClinGen:CA023283	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.119G>A (p.Ser40Asn)	324	APC	Uncertain significance	rs587778028	RCV000646658;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043533	112043533	G	A	5:g.112043533G>A	ClinGen:CA360612041	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.119G>T (p.Ser40Ile)	324	APC	Uncertain significance	rs587778028	RCV001317084;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043533	112043533	G	T	112043533	-
NM_001127511.3(APC):c.120C>A (p.Ser40Arg)	324	APC	Uncertain significance	rs1750613117	RCV001295321;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043534	112043534	C	A	112043534	-
NM_001127511.3(APC):c.120C>T (p.Ser40=)	324	APC	Uncertain significance	-1	RCV001869874;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043534	112043534	C	T	112043534	-
NM_001127511.3(APC):c.121C>G (p.Pro41Ala)	324	APC	Uncertain significance	rs1248809012	RCV000646688;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043535	112043535	C	G	NC_000005.9:g.112043535C>G	ClinGen:CA360612047	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.122C>T (p.Pro41Leu)	324	APC	Conflicting interpretations of pathogenicity	rs1057517584	RCV000410173;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043536	112043536	C	T	5:g.112043536C>T	ClinGen:CA16042079	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.122C>G (p.Pro41Arg)	324	APC	Uncertain significance	rs1057517584	RCV001337376;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043536	112043536	C	G	112043536	-
NM_001127511.3(APC):c.123G>A (p.Pro41=)	324	APC	Uncertain significance	rs1189155420	RCV000646641;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043537	112043537	G	A	5:g.112043537G>A	ClinGen:CA650199593	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.123G>T (p.Pro41=)	324	APC	Uncertain significance	rs1189155420	RCV000646559;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043537	112043537	G	T	5:g.112043537G>T	ClinGen:CA561890306	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.123G>C (p.Pro41=)	324	APC	Uncertain significance	rs1189155420	RCV001301877;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043537	112043537	G	C	112043537	-
NM_001127511.3(APC):c.123_124insTACTTCT (p.Gly42fs)	324	APC	Uncertain significance	-1	RCV001996465;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043537	112043538	G	GTACTTCT	112043537	-
NM_001127511.3(APC):c.124G>A (p.Gly42Ser)	324	APC	Uncertain significance	rs1057517582	RCV000411411;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043538	112043538	G	A	NC_000005.9:g.112043538G>A	ClinGen:CA16042080	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.125G>A (p.Gly42Asp)	324	APC	Conflicting interpretations of pathogenicity	rs1057517570	RCV000409742\|RCV000679421;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112043539	112043539	G	A	NC_000005.9:g.112043539G>A	ClinGen:CA16042081	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.125G>C (p.Gly42Ala)	324	APC	Uncertain significance	rs1057517570	RCV001326936;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043539	112043539	G	C	112043539	-
NM_001127511.3(APC):c.127G>A (p.Gly43Ser)	324	APC	Uncertain significance	rs1171615515	RCV000814998;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043541	112043541	G	A	5:g.112043541G>A	-
NM_001127511.3(APC):c.129C>T (p.Gly43=)	324	APC	Uncertain significance	rs1750614449	RCV001345014;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043543	112043543	C	T	112043543	-
NM_001127511.3(APC):c.130G>A (p.Ala44Thr)	324	APC	Conflicting interpretations of pathogenicity	rs367773779	RCV000412427;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043544	112043544	G	A	NC_000005.9:g.112043544G>A	ClinGen:CA053928	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.130G>C (p.Ala44Pro)	324	APC	Uncertain significance	rs367773779	RCV000533875;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043544	112043544	G	C	NC_000005.9:g.112043544G>C	ClinGen:CA360612075	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.131C>G (p.Ala44Gly)	324	APC	Uncertain significance	rs1750614704	RCV001305391;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043545	112043545	C	G	112043545	-
NM_001127511.3(APC):c.133C>T (p.Arg45Cys)	324	APC	Uncertain significance	rs755954869	RCV000549716;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043547	112043547	C	T	NC_000005.9:g.112043547C>T	ClinGen:CA053936	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.133C>A (p.Arg45Ser)	324	APC	Uncertain significance	-1	RCV001364644;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043547	112043547	C	A	112043547	-
NM_001127511.3(APC):c.133C>G (p.Arg45Gly)	324	APC	Uncertain significance	-1	RCV001366854;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043547	112043547	C	G	112043547	-
NM_001127511.3(APC):c.134G>C (p.Arg45Pro)	324	APC	Uncertain significance	rs1004213568	RCV000646679;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043548	112043548	G	C	5:g.112043548G>C	ClinGen:CA124925217	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.134G>A (p.Arg45His)	324	APC	Uncertain significance	rs1004213568	RCV000662997;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043548	112043548	G	A	5:g.112043548G>A	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.136A>C (p.Thr46Pro)	324	APC	Uncertain significance	rs766151900	RCV000646578;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043550	112043550	A	C	NC_000005.9:g.112043550A>C	ClinGen:CA054190	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.136A>G (p.Thr46Ala)	324	APC	Uncertain significance	-1	RCV002025495;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043550	112043550	A	G	112043550	-
NM_001127511.3(APC):c.137C>T (p.Thr46Ile)	324	APC	Uncertain significance	rs1016971418	RCV000614706\|RCV001309343;	N	MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043551	112043551	C	T	5:g.112043551C>T	ClinGen:CA360612118	CN169374 not specified;
NM_001127511.3(APC):c.140C>G (p.Ser47Cys)	324	APC	Uncertain significance	rs1750615769	RCV001324696;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043554	112043554	C	G	112043554	-
NM_001127511.3(APC):c.140C>T (p.Ser47Phe)	324	APC	Uncertain significance	-1	RCV001946127;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043554	112043554	C	T	112043554	-
NM_001127511.3(APC):c.141T>G (p.Ser47=)	324	APC	Uncertain significance	-1	RCV001373746;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043555	112043555	T	G	112043555	-
NM_001127511.3(APC):c.141T>A (p.Ser47=)	324	APC	Uncertain significance	-1	RCV002030933;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043555	112043555	T	A	112043555	-
NM_001127511.3(APC):c.145C>T (p.His49Tyr)	324	APC	Uncertain significance	rs933496509	RCV001346981;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043559	112043559	C	T	112043559	-
NM_001127511.3(APC):c.146del (p.His49fs)	324	APC	Uncertain significance	rs1750616412	RCV001309908;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043560	112043560	CA	C	112043559	-
NM_001127511.3(APC):c.146A>G (p.His49Arg)	324	APC	Uncertain significance	rs1191401517	RCV001306050;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043560	112043560	A	G	112043560	-
NM_001127511.3(APC):c.148T>C (p.Trp50Arg)	324	APC	Uncertain significance	rs1488176769	RCV000646675;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043562	112043562	T	C	5:g.112043562T>C	ClinGen:CA360612160	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.148T>G (p.Trp50Gly)	324	APC	Uncertain significance	-1	RCV001363263;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043562	112043562	T	G	112043562	-
NM_001127511.3(APC):c.149G>C (p.Trp50Ser)	324	APC	Uncertain significance	rs1366978080	RCV000662474;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043563	112043563	G	C	5:g.112043563G>C	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.150G>A (p.Trp50Ter)	324	APC	Uncertain significance	rs1163442131	RCV000534823;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043564	112043564	G	A	5:g.112043564G>A	ClinGen:CA360612168	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.150G>C (p.Trp50Cys)	324	APC	Uncertain significance	-1	RCV001936523;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043564	112043564	G	C	112043564	-
NM_001127511.3(APC):c.151G>A (p.Ala51Thr)	324	APC	Uncertain significance	rs1750617136	RCV001342161;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043565	112043565	G	A	112043565	-
NM_001127511.3(APC):c.151G>C (p.Ala51Pro)	324	APC	Uncertain significance	-1	RCV001892189;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043565	112043565	G	C	112043565	-
NM_001127511.3(APC):c.152C>T (p.Ala51Val)	324	APC	Uncertain significance	-1	RCV001371893;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043566	112043566	C	T	112043566	-
NM_001127511.3(APC):c.153G>T (p.Ala51=)	324	APC	Uncertain significance	rs1750617341	RCV001321462;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043567	112043567	G	T	112043567	-
NM_001127511.3(APC):c.153G>A (p.Ala51=)	324	APC	Uncertain significance	-1	RCV001932427;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043567	112043567	G	A	112043567	-
NM_001127511.3(APC):c.154A>G (p.Ser52Gly)	324	APC	Uncertain significance	rs1554060315	RCV000646564;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043568	112043568	A	G	5:g.112043568A>G	ClinGen:CA360612183	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.155G>C (p.Ser52Thr)	324	APC	Uncertain significance	rs1554060317	RCV000646549;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043569	112043569	G	C	5:g.112043569G>C	ClinGen:CA360612189	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.156C>T (p.Ser52=)	324	APC	Uncertain significance	rs1051954601	RCV001319834;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043570	112043570	C	T	112043570	-
NM_001127511.3(APC):c.156C>A (p.Ser52Arg)	324	APC	Uncertain significance	-1	RCV001370584;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043570	112043570	C	A	112043570	-
NM_001127511.3(APC):c.157G>C (p.Val53Leu)	324	APC	Uncertain significance	rs888841371	RCV000560864;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043571	112043571	G	C	NC_000005.9:g.112043571G>C	ClinGen:CA124925269	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.159C>T (p.Val53=)	324	APC	Uncertain significance	rs1277365767	RCV001303660;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043573	112043573	C	T	112043573	-
NM_001127511.3(APC):c.159C>G (p.Val53=)	324	APC	Uncertain significance	-1	RCV001970881;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043573	112043573	C	G	112043573	-
NM_001127511.3(APC):c.160T>C (p.Trp54Arg)	324	APC	Uncertain significance	-1	RCV001932337;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043574	112043574	T	C	112043574	-
NM_001127511.3(APC):c.161G>A (p.Trp54Ter)	324	APC	Uncertain significance	rs1750617951	RCV001310027;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043575	112043575	G	A	112043575	-
NM_001127511.3(APC):c.161G>C (p.Trp54Ser)	324	APC	Uncertain significance	-1	RCV001872758;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043575	112043575	G	C	112043575	-
NM_001127511.3(APC):c.163C>A (p.Gln55Lys)	324	APC	Uncertain significance	rs1312050427	RCV000646582;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043577	112043577	C	A	NC_000005.9:g.112043577C>A	ClinGen:CA360612224	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.163C>T (p.Gln55Ter)	324	APC	Uncertain significance	rs1312050427	RCV001346504;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043577	112043577	C	T	112043577	-
NM_001127511.3(APC):c.164A>G (p.Gln55Arg)	324	APC	Uncertain significance	-1	RCV002028124;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043578	112043578	A	G	112043578	-
NM_001127511.3(APC):c.165G>C (p.Gln55His)	324	APC	Uncertain significance	rs1369553472	RCV001346693;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043579	112043579	G	C	112043579	-
NM_001127511.3(APC):c.165+1G>A	324	APC	Uncertain significance	rs1239946140	RCV000646550;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043580	112043580	G	A	NC_000005.9:g.112043580G>A	ClinGen:CA360612237	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.165+6_165+9del	324	APC	Uncertain significance	-1	RCV001919883;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043580	112043583	GGTGA	G	112043579	-
NM_001127511.3(APC):c.165+3G>T	324	APC	Uncertain significance	rs765384591	RCV000646606;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043582	112043582	G	T	5:g.112043582G>T	ClinGen:CA124925282	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.165+4A>G	324	APC	Uncertain significance	rs1750618752	RCV001327098;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043583	112043583	A	G	112043583	-
NM_001127511.3(APC):c.165+9G>A	324	APC	Uncertain significance	-1	RCV001978200;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043588	112043588	G	A	112043588	-
NM_001127511.3(APC):c.165+10G>T	324	APC	Uncertain significance	rs1296416614	RCV000646620;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043589	112043589	G	T	NC_000005.9:g.112043589G>T	ClinGen:CA561890341	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.165+10_165+18del	324	APC	Uncertain significance	rs1750619239	RCV001351067;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043589	112043597	GGCTGCAGGC	G	112043588	-
NM_001127511.3(APC):c.165+13G>A	324	APC	Uncertain significance	-1	RCV001932623;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043592	112043592	G	A	112043592	-
NM_001127511.3(APC):c.165+15A>G	324	APC	Uncertain significance	rs1750619444	RCV001326407;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043594	112043594	A	G	112043594	-
NM_001127511.3(APC):c.165+16G>C	324	APC	Benign	rs1223298182	RCV000646649;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043595	112043595	G	C	NC_000005.9:g.112043595G>C	ClinGen:CA658796620	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.165+16G>A	324	APC	Uncertain significance	rs1223298182	RCV001324244;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043595	112043595	G	A	112043595	-
NM_001127511.3(APC):c.165+17G>T	324	APC	Uncertain significance	rs1057517556	RCV000410745\|RCV001861405;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043596	112043596	G	T	NC_000005.9:g.112043596G>T	ClinGen:CA16042082	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.165+17G>A	324	APC	Uncertain significance	rs1057517556	RCV000546057;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043596	112043596	G	A	NC_000005.9:g.112043596G>A	ClinGen:CA658655905	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.165+19A>G	324	APC	Uncertain significance	rs1487833679	RCV000535698;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043598	112043598	A	G	5:g.112043598A>G	ClinGen:CA561890344	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.165+20T>C	324	APC	Uncertain significance	rs1191699028	RCV000557239;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043599	112043599	T	C	5:g.112043599T>C	ClinGen:CA658655906	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.165+20T>A	324	APC	Uncertain significance	-1	RCV001962394;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112043599	112043599	T	A	112043599	-
NC_000005.10:g.(?_112737024)_(112844132_?)del	324	APC	Pathogenic	-1	RCV000560788;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112072721	112179829	na	na		-	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.(?_112072721)_(112111440_?)dup	324	APC	Likely pathogenic	-1	RCV000550240\|RCV001858057;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112072721	112111440	na	na		-	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.10:g.(?_112737024)_(112766416_?)del	324	APC	Pathogenic	-1	RCV000646697;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112072721	112102113	na	na		-	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.(?_112072721)_(112090728_?)dup	324	APC	Likely pathogenic	-1	RCV000708496;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112072721	112090728	na	na		-	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.10:g.(?_112737024)_(112844136_?)del	324	APC	Pathogenic	-1	RCV000813966\|RCV001869257;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112072721	112179833	na	na		-
NC_000005.10:g.(?_112737024)_(112737888_?)dup	324	APC	Uncertain significance	-1	RCV001032266\|RCV001862450;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112072721	112073585	na	na	-1	-
NC_000005.9:g.(?_112072721)_(112090732_?)dup	324	APC	Likely pathogenic	-1	RCV001378397;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112072721	112090732	na	na	-1	-
NC_000005.9:g.(?_112072721)_(112179823_?)del	324	APC	Pathogenic	-1	RCV001385949;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112072721	112179823	na	na	-1	-
NC_000005.9:g.(?_112072721)_(112073585_?)del	324	APC	Uncertain significance	-1	RCV001864645;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112072721	112073585	na	na	-1	-
NC_000005.9:g.(?_112072721)_(112116610_?)dup	324	APC	Likely pathogenic	-1	RCV002042776;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112072721	112116610	na	na	-1	-
NM_001127511.3(APC):c.166-29015A>T	324	APC	Benign	rs75581138	RCV000602321\|RCV000663007;	N	MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112073008	112073008	A	T	5:g.112073008A>T	ClinGen:CA124948485	C2713442 175100 Familial adenomatous polyposis 1;
NM_001127511.3(APC):c.166-28546T>C	324	APC	Benign/Likely benign	rs113017087	RCV000208994\|RCV000615963\|RCV001519059;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112073477	112073477	T	C	5:g.112073477T>C	ClinGen:CA351238	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.5(APC):c.-85_*2113del	324	APC	Pathogenic	-1	RCV000232813;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112073556	112181936	na	na		-	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.10:g.(?_112737859)_(112815593_?)del	324	APC	Pathogenic	-1	RCV000470226;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112073556	112151290	na	na		-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.-43A>C	324	APC	Uncertain significance	rs879254014	RCV000235958\|RCV000708948;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112073598	112073598	A	C	NC_000005.9:g.112073598A>C	ClinGen:CA10584232	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.-19+45G>A	324	APC	Likely benign	rs370011472	RCV000829439\|RCV000987547;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112073667	112073667	G	A	5:g.112073667G>A	-
NM_000038.6(APC):c.-19+416C>T	324	APC	Likely benign	rs976627265	RCV000987548;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112074038	112074038	C	T	5:g.112074038C>T	-
NC_000005.9:g.(?_112090570)_(112157688_?)dup	324	APC	Likely pathogenic	-1	RCV000469367;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090570	112157688	na	na		-	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.(?_112090578)_(112111444_?)dup	324	APC	Uncertain significance	-1	RCV000813971;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090578	112111444	na	na		-
NC_000005.9:g.(?_112090582)_(112111440_?)dup	324	APC	Uncertain significance	-1	RCV000549344;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090582	112111440	na	na		-	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.(?_112090582)_(112137086_?)dup	324	APC	Likely pathogenic	-1	RCV001378396;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090582	112137086	na	na	-1	-
NC_000005.9:g.(?_112090582)_(112157694_?)dup	324	APC	Likely pathogenic	-1	RCV001378245;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090582	112157694	na	na	-1	-
NM_000038.6(APC):c.-2_135+1274del	324	APC	Pathogenic	-1	RCV001355291;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090586	112091996	AGGATGGCTGCAGCTTCATATGATCAGTTGTTAAAGCAAGTTGAGGCACTGAAGATGGAGAACTCAAATCTTCGACAAGAGCTAGAAGATAATTCCAATCATCTTACAAA	A	112090585	-
NC_000005.10:g.(?_112754891)_(112767400_?)del	324	APC	Pathogenic	-1	RCV001033106\|RCV001873435;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090588	112103097	na	na	-1	-
NC_000005.10:g.(?_112754891)_(112767400_?)dup	324	APC	Likely pathogenic	-1	RCV001031137\|RCV001862441;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090588	112103097	na	na	-1	-
NC_000005.10:g.(?_112754891)_(112775747_?)dup	324	APC	Uncertain significance	-1	RCV001032858\|RCV001862454;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090588	112111444	na	na	-1	-
NC_000005.9:g.(?_112090588)_(112179823_?)del	324	APC	Pathogenic	-1	RCV001385948;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090588	112179823	na	na	-1	-
NC_000005.9:g.(?_112090588)_(112179823_?)dup	324	APC	Uncertain significance	-1	RCV001899670;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090588	112179823	na	na	-1	-
NM_000038.6(APC):c.4G>A (p.Ala2Thr)	324	APC	Uncertain significance	rs569523442	RCV001321032;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090591	112090591	G	A	112090591	-
NM_000038.6(APC):c.6T>C (p.Ala2=)	324	APC	Likely benign	-1	RCV001404403;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090593	112090593	T	C	112090593	-
NM_000038.6(APC):c.10G>C (p.Ala4Pro)	324	APC	Uncertain significance	rs774219012	RCV000466564\|RCV000677758\|RCV001017299\|RCV001753908;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0002032,MedGen:C0699790\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202	5	112090597	112090597	G	C	NC_000005.9:g.112090597G>C	ClinGen:CA026700	C0699790 114500 Carcinoma of colon;
NM_000038.6(APC):c.10G>T (p.Ala4Ser)	324	APC	Uncertain significance	rs774219012	RCV000562185\|RCV001042928;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090597	112090597	G	T	5:g.112090597G>T	ClinGen:CA16021356	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.14C>T (p.Ser5Leu)	324	APC	Uncertain significance	rs373718658	RCV000229070\|RCV000589294\|RCV000775115;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112090601	112090601	C	T	NC_000005.9:g.112090601C>T	ClinGen:CA028004	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.14C>A (p.Ser5Ter)	324	APC	Conflicting interpretations of pathogenicity	rs373718658	RCV000474392\|RCV001011888;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112090601	112090601	C	A	NC_000005.9:g.112090601C>A	ClinGen:CA16021363	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.14del (p.Ser5fs)	324	APC	Pathogenic	rs1554067104	RCV000646367;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090601	112090601	TC	T	NC_000005.9:g.112090601del	ClinGen:CA658796564	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.15A>G (p.Ser5=)	324	APC	Conflicting interpretations of pathogenicity	rs1554067106	RCV000561552\|RCV001039653;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090602	112090602	A	G	NC_000005.9:g.112090602A>G	ClinGen:CA445752302	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.15A>C (p.Ser5=)	324	APC	Likely benign	-1	RCV001458844;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090602	112090602	A	C	112090602	-
NM_000038.6(APC):c.18T>C (p.Tyr6=)	324	APC	Likely benign	rs786202301	RCV000165043\|RCV000646687\|RCV001435876;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090605	112090605	T	C	5:g.112090605T>C	ClinGen:CA006281	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.20A>G (p.Asp7Gly)	324	APC	Uncertain significance	rs1060503296	RCV000471396;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090607	112090607	A	G	NC_000005.9:g.112090607A>G	ClinGen:CA16021377	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.23A>G (p.Gln8Arg)	324	APC	Uncertain significance	rs1754782964	RCV001037599;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090610	112090610	A	G	5:g.112090610A>G	-
NM_000038.6(APC):c.32dup (p.Gln12fs)	324	APC	Pathogenic	rs1561444620	RCV000772573\|RCV000808751;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090616	112090617	T	TA	NC_000005.9:g.112090619dup	-
NM_000038.6(APC):c.35A>G (p.Gln12Arg)	324	APC	Uncertain significance	rs1754783765	RCV001208336;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090622	112090622	A	G	5:g.112090622A>G	-
NM_000038.6(APC):c.36A>G (p.Gln12=)	324	APC	Likely benign	rs864622288	RCV000204299\|RCV000433481\|RCV000566559;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112090623	112090623	A	G	5:g.112090623A>G	ClinGen:CA348545	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.42G>A (p.Glu14=)	324	APC	Likely benign	rs1554067113	RCV000565251\|RCV002060538;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090629	112090629	G	A	NC_000005.9:g.112090629G>A	ClinGen:CA445752364	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.45A>C (p.Ala15=)	324	APC	Likely benign	-1	RCV001406866;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090632	112090632	A	C	112090632	-
NM_000038.6(APC):c.46C>T (p.Leu16=)	324	APC	Likely benign	rs1057520603	RCV000428439\|RCV000775897\|RCV001423153;	N	MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090633	112090633	C	T	5:g.112090633C>T	ClinGen:CA16604756	CN169374 not specified;
NM_000038.6(APC):c.46C>G (p.Leu16Val)	324	APC	Uncertain significance	-1	RCV001948724;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090633	112090633	C	G	112090633	-
NM_000038.6(APC):c.47T>C (p.Leu16Pro)	324	APC	Uncertain significance	rs1581121721	RCV000806064;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090634	112090634	T	C	5:g.112090634T>C	-
NM_000038.6(APC):c.48G>A (p.Leu16=)	324	APC	Likely benign	-1	RCV001501998;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090635	112090635	G	A	112090635	-
NM_000038.6(APC):c.52A>G (p.Met18Val)	324	APC	Uncertain significance	rs587782402	RCV000131435\|RCV000502641\|RCV001350823;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0002032,MedGen:C0699790\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090639	112090639	A	G	5:g.112090639A>G	ClinGen:CA010033	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.53T>A (p.Met18Lys)	324	APC	Uncertain significance	rs200960071	RCV000034418\|RCV000130887\|RCV000701375;	N	MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090640	112090640	T	A	5:g.112090640T>A	ClinGen:CA010386	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.54G>A (p.Met18Ile)	324	APC	Uncertain significance	rs772873692	RCV000465022\|RCV000581033;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112090641	112090641	G	A	NC_000005.9:g.112090641G>A	ClinGen:CA042134	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.55G>T (p.Glu19Ter)	324	APC	Pathogenic	rs1754786861	RCV001245830;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090642	112090642	G	T	5:g.112090642G>T	-
NM_000038.6(APC):c.56A>C (p.Glu19Ala)	324	APC	Uncertain significance	rs1754787233	RCV001060545;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090643	112090643	A	C	5:g.112090643A>C	-
NM_000038.6(APC):c.57G>C (p.Glu19Asp)	324	APC	Uncertain significance	rs1754787495	RCV001065510;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090644	112090644	G	C	5:g.112090644G>C	-
NM_000038.6(APC):c.57G>T (p.Glu19Asp)	324	APC	Uncertain significance	rs1754787495	RCV001235616;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090644	112090644	G	T	5:g.112090644G>T	-
NM_000038.6(APC):c.59A>C (p.Asn20Thr)	324	APC	Uncertain significance	-1	RCV001997526;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090646	112090646	A	C	112090646	-
NM_000038.6(APC):c.60C>T (p.Asn20=)	324	APC	Likely benign	rs780155240	RCV000166303\|RCV000197299\|RCV001697159\|RCV001844061;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202\|MedGen:CN169374	5	112090647	112090647	C	T	5:g.112090647C>T	ClinGen:CA010920	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.62C>G (p.Ser21Ter)	324	APC	Pathogenic	-1	RCV001889840;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090649	112090649	C	G	112090649	-
NM_000038.6(APC):c.64A>G (p.Asn22Asp)	324	APC	Uncertain significance	rs1415062077	RCV000562861\|RCV000758737\|RCV001211866;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090651	112090651	A	G	NC_000005.9:g.112090651A>G	ClinGen:CA16021480	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.64A>C (p.Asn22His)	324	APC	Uncertain significance	rs1415062077	RCV001039985;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090651	112090651	A	C	5:g.112090651A>C	-
NM_000038.6(APC):c.67C>G (p.Leu23Val)	324	APC	Uncertain significance	rs372367350	RCV000575621\|RCV000646454\|RCV001797110;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112090654	112090654	C	G	NC_000005.9:g.112090654C>G	ClinGen:CA046202	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.70C>T (p.Arg24Ter)	324	APC	Pathogenic/Likely pathogenic	rs145945630	RCV000164002\|RCV000227124\|RCV000482864\|RCV000508297\|RCV000763534\|RCV000844605\|RCV001353710;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202\|MedGen:CN169374\|Human Phenotype Ontology:HP:0006753,MONDO:MONDO:0021085,MedGen:C0038356; MedGen:C1851124,OMIM:135290, Orphanet	5	112090657	112090657	C	T	NC_000005.9:g.112090657C>T	ClinGen:CA012843	CN240755 Familial adenomatous polyposis;
NM_000038.6(APC):c.71G>A (p.Arg24Gln)	324	APC	Uncertain significance	rs878853469	RCV000230342\|RCV001854825;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090658	112090658	G	A	NC_000005.9:g.112090658G>A	ClinGen:CA10582272	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.71G>T (p.Arg24Leu)	324	APC	Uncertain significance	rs878853469	RCV000707464\|RCV001026152;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112090658	112090658	G	T	NC_000005.9:g.112090658G>T	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.74_75del (p.Gln25fs)	324	APC	Pathogenic	rs1554067124	RCV000536195\|RCV000657188;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112090661	112090662	CAA	C	NC_000005.9:g.112090661_112090662del	ClinGen:CA658657468	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.74A>C (p.Gln25Pro)	324	APC	Uncertain significance	-1	RCV002031453;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090661	112090661	A	C	112090661	-
NM_000038.6(APC):c.75A>G (p.Gln25=)	324	APC	Likely benign	rs876659361	RCV000222595\|RCV000233328\|RCV000433787;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374	5	112090662	112090662	A	G	5:g.112090662A>G	ClinGen:CA10578282	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.76G>C (p.Glu26Gln)	324	APC	Uncertain significance	rs1554067127	RCV000566833\|RCV001039073;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090663	112090663	G	C	5:g.112090663G>C	ClinGen:CA16021503	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.78G>A (p.Glu26=)	324	APC	Likely benign	rs1561444861	RCV000773727\|RCV000921715\|RCV001488910;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090665	112090665	G	A	NC_000005.9:g.112090665G>A	-
NM_000038.6(APC):c.79C>T (p.Leu27=)	324	APC	Likely benign	rs786202128	RCV000164787\|RCV002053969;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090666	112090666	C	T	5:g.112090666C>T	ClinGen:CA014234	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.81A>C (p.Leu27=)	324	APC	Likely benign	rs759312196	RCV001186757\|RCV001499003;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090668	112090668	A	C	5:g.112090668A>C	-
NM_000038.6(APC):c.81A>G (p.Leu27=)	324	APC	Likely benign	rs759312196	RCV001187111\|RCV002068459;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090668	112090668	A	G	5:g.112090668A>G	-
NM_000038.6(APC):c.82G>A (p.Glu28Lys)	324	APC	Uncertain significance	rs1754792844	RCV001340165;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090669	112090669	G	A	112090669	-
NM_000038.6(APC):c.83A>G (p.Glu28Gly)	324	APC	Uncertain significance	rs1754793089	RCV001059335;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090670	112090670	A	G	5:g.112090670A>G	-
NM_000038.6(APC):c.84A>G (p.Glu28=)	324	APC	Likely benign	rs1581121956	RCV000944825\|RCV001437301;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090671	112090671	A	G	5:g.112090671A>G	-
NM_000038.6(APC):c.85G>T (p.Asp29Tyr)	324	APC	Uncertain significance	rs1195191600	RCV001071255;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090672	112090672	G	T	5:g.112090672G>T	-
NM_000038.6(APC):c.86A>T (p.Asp29Val)	324	APC	Uncertain significance	rs1754793886	RCV001046575;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090673	112090673	A	T	5:g.112090673A>T	-
NM_000038.6(APC):c.86A>C (p.Asp29Ala)	324	APC	Uncertain significance	rs1754793886	RCV001215830;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090673	112090673	A	C	5:g.112090673A>C	-
NM_000038.6(APC):c.86A>G (p.Asp29Gly)	324	APC	Uncertain significance	rs1754793886	RCV001294673;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090673	112090673	A	G	112090673	-
NM_000038.6(APC):c.87T>G (p.Asp29Glu)	324	APC	Uncertain significance	rs1561444926	RCV000693074;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090674	112090674	T	G	5:g.112090674T>G	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.88A>G (p.Asn30Asp)	324	APC	Uncertain significance	rs1754795045	RCV001053884;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090675	112090675	A	G	5:g.112090675A>G	-
NM_000038.6(APC):c.94A>G (p.Asn32Asp)	324	APC	Uncertain significance	rs587781972	RCV000130360\|RCV000474411;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090681	112090681	A	G	5:g.112090681A>G	ClinGen:CA016000	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.94A>T (p.Asn32Tyr)	324	APC	Uncertain significance	rs587781972	RCV000562593\|RCV001213289;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090681	112090681	A	T	5:g.112090681A>T	ClinGen:CA16021546	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.95A>G (p.Asn32Ser)	324	APC	Conflicting interpretations of pathogenicity	rs539108537	RCV000202147\|RCV000204603\|RCV000569857\|RCV000677775\|RCV000656743\|RCV001762426;	N	MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|Human Phenotype Ontology:HP:0006753,MONDO:MONDO:0021085,MedGen:C0038356\|MedGen:CN517202\|MONDO:MONDO:0005575,MedGen:C0346629,	5	112090682	112090682	A	G	5:g.112090682A>G	ClinGen:CA051346	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.95A>T (p.Asn32Ile)	324	APC	Uncertain significance	rs539108537	RCV001343537;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090682	112090682	A	T	112090682	-
NM_000038.6(APC):c.102T>C (p.Leu34=)	324	APC	Likely benign	rs1581122045	RCV000941456\|RCV001438173;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090689	112090689	T	C	5:g.112090689T>C	-
NM_000038.6(APC):c.104C>A (p.Thr35Lys)	324	APC	Uncertain significance	rs1581122062	RCV000817688;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090691	112090691	C	A	5:g.112090691C>A	-
NM_000038.6(APC):c.108del (p.Lys36fs)	324	APC	Pathogenic	rs1554067141	RCV000646412;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090692	112090692	CA	C	5:g.112090692_112090692del	ClinGen:CA658796565	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.105A>C (p.Thr35=)	324	APC	Likely benign	rs1581122087	RCV000977323\|RCV001491498;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090692	112090692	A	C	5:g.112090692A>C	-
NM_000038.6(APC):c.111G>T (p.Leu37=)	324	APC	Likely benign	rs1554067149	RCV000977864\|RCV001395008;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090698	112090698	G	T	5:g.112090698G>T	-
NM_000038.6(APC):c.113A>C (p.Glu38Ala)	324	APC	Uncertain significance	rs1754800670	RCV001216196;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090700	112090700	A	C	5:g.112090700A>C	-
NM_000038.6(APC):c.115A>G (p.Thr39Ala)	324	APC	Uncertain significance	rs1581122131	RCV000817243;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090702	112090702	A	G	5:g.112090702A>G	-
NM_000038.6(APC):c.116C>G (p.Thr39Ser)	324	APC	Uncertain significance	rs1561445008	RCV000776690\|RCV001345805;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090703	112090703	C	G	NC_000005.9:g.112090703C>G	-
NM_000038.6(APC):c.116C>A (p.Thr39Asn)	324	APC	Uncertain significance	-1	RCV002040303;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090703	112090703	C	A	112090703	-
NM_000038.6(APC):c.119A>G (p.Glu40Gly)	324	APC	Uncertain significance	-1	RCV001899933;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090706	112090706	A	G	112090706	-
NM_000038.6(APC):c.120G>A (p.Glu40=)	324	APC	Benign/Likely benign	rs142720069	RCV000123674\|RCV000201994\|RCV000340295\|RCV000589882\|RCV001082954;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374\|MedGen:CN239210\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090707	112090707	G	A	NC_000005.9:g.112090707G>A	ClinGen:CA004090	CN239210 APC-Associated Polyposis Disorders;
NM_000038.6(APC):c.121G>A (p.Ala41Thr)	324	APC	Uncertain significance	rs1554067157	RCV000583824\|RCV000689611;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090708	112090708	G	A	5:g.112090708G>A	ClinGen:CA16021606	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.121G>T (p.Ala41Ser)	324	APC	Uncertain significance	rs1554067157	RCV000809176;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090708	112090708	G	T	5:g.112090708G>T	-
NM_000038.6(APC):c.123A>G (p.Ala41=)	324	APC	Likely benign	rs1561445056	RCV000777406\|RCV000978212;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090710	112090710	A	G	NC_000005.9:g.112090710A>G	-
NM_000038.6(APC):c.124T>G (p.Ser42Ala)	324	APC	Uncertain significance	rs1754803343	RCV001068849\|RCV001806012;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112090711	112090711	T	G	5:g.112090711T>G	-
NM_000038.6(APC):c.125C>A (p.Ser42Tyr)	324	APC	Uncertain significance	rs781207121	RCV001318051;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090712	112090712	C	A	112090712	-
NM_000038.6(APC):c.130A>G (p.Met44Val)	324	APC	Uncertain significance	rs1424437002	RCV001063169;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090717	112090717	A	G	5:g.112090717A>G	-
NM_000038.6(APC):c.132dup (p.Lys45fs)	324	APC	Pathogenic	rs1561445097	RCV000703121;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090718	112090719	T	TG	5:g.112090718_112090719insG	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.135G>A (p.Lys45=)	324	APC	Uncertain significance	rs1754804397	RCV001064744;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090722	112090722	G	A	5:g.112090722G>A	-
NM_000038.6(APC):c.135+1G>T	324	APC	Likely pathogenic	rs750508765	RCV000570470\|RCV000646409\|RCV000758720;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112090723	112090723	G	T	NC_000005.9:g.112090723G>T	ClinGen:CA360617454	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.135+3A>T	324	APC	Uncertain significance	rs1754805091	RCV001303519;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090725	112090725	A	T	112090725	-
NM_000038.6(APC):c.135+7A>G	324	APC	Likely benign	-1	RCV001464353;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090729	112090729	A	G	112090729	-
NM_000038.6(APC):c.135+8G>C	324	APC	Conflicting interpretations of pathogenicity	rs1554067166	RCV000581428\|RCV000646568;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090730	112090730	G	C	NC_000005.9:g.112090730G>C	ClinGen:CA658683397	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.135+12G>T	324	APC	Likely benign	rs1057524184	RCV000440035\|RCV000775921\|RCV002063608;	N	MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112090734	112090734	G	T	5:g.112090734G>T	ClinGen:CA16604641	CN169374 not specified;
NM_000038.6(APC):c.136-20T>C	324	APC	Likely benign	rs1219730982	RCV000581295\|RCV002060556;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102003	112102003	T	C	5:g.112102003T>C	ClinGen:CA561903216	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.136-19A>G	324	APC	Likely benign	rs778690797	RCV000583413\|RCV002060555;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102004	112102004	A	G	5:g.112102004A>G	ClinGen:CA027282	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.136-18T>C	324	APC	Likely benign	rs1261769588	RCV000583883\|RCV002061963;	N	MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102005	112102005	T	C	5:g.112102005T>C	ClinGen:CA561903217	CN169374 not specified;
NM_000038.6(APC):c.136-16G>T	324	APC	Likely benign	-1	RCV002152249;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102007	112102007	G	T	112102007	-
NM_000038.6(APC):c.136-12T>C	324	APC	Likely benign	rs1554069478	RCV000582406\|RCV001637091\|RCV002060554;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102011	112102011	T	C	NC_000005.9:g.112102011T>C	ClinGen:CA658683398	C0027672 Hereditary cancer-predisposing syndrome;
NC_000005.10:g.(?_112766316)_(112844136_?)del	324	APC	Pathogenic	-1	RCV000801359;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102013	112179833	na	na		-
NC_000005.10:g.(?_112766316)_(112844136_?)dup	324	APC	Uncertain significance	-1	RCV001032267;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102013	112179833	na	na	-1	-
NC_000005.9:g.(?_112102013)_(112179823_?)dup	324	APC	Uncertain significance	-1	RCV002018025;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102013	112179823	na	na	-1	-
NC_000005.9:g.(?_112102013)_(112103097_?)del	324	APC	Pathogenic	-1	RCV001903135;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102013	112103097	na	na	-1	-
NC_000005.9:g.(?_112102013)_(112179823_?)del	324	APC	Pathogenic	-1	RCV001964649;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102013	112179823	na	na	-1	-
NM_000038.6(APC):c.136-7T>C	324	APC	Likely benign	-1	RCV002095782;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102016	112102016	T	C	112102016	-
NM_000038.6(APC):c.136-5A>G	324	APC	Conflicting interpretations of pathogenicity	rs1581159924	RCV000981511\|RCV001011054;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102018	112102018	A	G	5:g.112102018A>G	-
NM_000038.6(APC):c.136-4A>G	324	APC	Uncertain significance	rs1297141781	RCV001187846\|RCV001296916;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102019	112102019	A	G	5:g.112102019A>G	-
NM_000038.6(APC):c.136-3C>T	324	APC	Conflicting interpretations of pathogenicity	rs1060503361	RCV000466444\|RCV001179769\|RCV001577551;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202	5	112102020	112102020	C	T	NC_000005.9:g.112102020C>T	ClinGen:CA16611599	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.136-3C>A	324	APC	Uncertain significance	rs1060503361	RCV001216758;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102020	112102020	C	A	5:g.112102020C>A	-
NM_000038.6(APC):c.136-2A>G	324	APC	Pathogenic/Likely pathogenic	rs886039625	RCV000254746\|RCV001064575;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102021	112102021	A	G	5:g.112102021A>G	ClinGen:CA10588375	CN517202 not provided;
NM_000038.6(APC):c.136-1G>A	324	APC	Likely pathogenic	rs1554069481	RCV000574643\|RCV000646364;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102022	112102022	G	A	5:g.112102022G>A	ClinGen:CA360617462	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.137_139del (p.Glu46del)	324	APC	Uncertain significance	-1	RCV001884763;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102023	112102025	GGAA	G	112102022	-
NM_000038.6(APC):c.138A>C (p.Glu46Asp)	324	APC	Uncertain significance	rs1429803547	RCV000823330;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102025	112102025	A	C	5:g.112102025A>C	-
NM_000038.6(APC):c.138A>G (p.Glu46=)	324	APC	Conflicting interpretations of pathogenicity	rs1429803547	RCV001011330\|RCV001862777;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102025	112102025	A	G	5:g.112102025A>G	-
NM_000038.6(APC):c.139G>A (p.Val47Ile)	324	APC	Uncertain significance	rs969611536	RCV000462825\|RCV000775730;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102026	112102026	G	A	NC_000005.9:g.112102026G>A	ClinGen:CA16021649	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.147_150del (p.Lys49fs)	324	APC	Pathogenic	rs587781694	RCV000129859\|RCV000502854\|RCV000497263\|RCV000552842\|RCV001778749;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0002032,MedGen:C0699790\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021055,MedGen:C0032580,OMIM:PS175100, Orphanet:733	5	112102032	112102035	TAAAC	T	5:g.112102032_112102035del	ClinGen:CA005200	CN240755 Familial adenomatous polyposis;
NM_000038.6(APC):c.146A>C (p.Lys49Thr)	324	APC	Uncertain significance	rs587781587	RCV000563070\|RCV000693872\|RCV001260373;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374	5	112102033	112102033	A	C	NC_000005.9:g.112102033A>C	ClinGen:CA16021664	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.148_149del (p.Gln50fs)	324	APC	Pathogenic	-1	RCV001936572;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102034	112102035	AAC	A	112102033	-
NM_000038.6(APC):c.147A>G (p.Lys49=)	324	APC	Likely benign	-1	RCV002162058;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102034	112102034	A	G	112102034	-
NM_000038.6(APC):c.148C>G (p.Gln50Glu)	324	APC	Uncertain significance	-1	RCV001359485;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102035	112102035	C	G	112102035	-
NM_000038.6(APC):c.148C>T (p.Gln50Ter)	324	APC	Pathogenic	-1	RCV001387446;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102035	112102035	C	T	112102035	-
NM_000038.6(APC):c.150A>G (p.Gln50=)	324	APC	Likely benign	-1	RCV002095466;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102037	112102037	A	G	112102037	-
NM_000038.6(APC):c.151C>T (p.Leu51=)	324	APC	Likely benign	rs1554069497	RCV000563260\|RCV001455213;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102038	112102038	C	T	5:g.112102038C>T	ClinGen:CA445752982	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.151C>G (p.Leu51Val)	324	APC	Uncertain significance	rs1554069497	RCV001233617;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102038	112102038	C	G	5:g.112102038C>G	-
NM_000038.6(APC):c.152T>A (p.Leu51Gln)	324	APC	Uncertain significance	rs1756317618	RCV001037451;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102039	112102039	T	A	5:g.112102039T>A	-
NM_000038.6(APC):c.152T>C (p.Leu51Pro)	324	APC	Uncertain significance	-1	RCV002047433;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102039	112102039	T	C	112102039	-
NM_000038.6(APC):c.153A>G (p.Leu51=)	324	APC	Likely benign	rs1554069500	RCV000569850\|RCV000978940;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102040	112102040	A	G	NC_000005.9:g.112102040A>G	ClinGen:CA445752984	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.156del (p.Gly53fs)	324	APC	Pathogenic	rs1581160123	RCV000810917\|RCV001356443;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112102042	112102042	CA	C	5:g.112102042_112102042del	-
NM_000038.6(APC):c.156A>C (p.Gln52His)	324	APC	Uncertain significance	-1	RCV001368150;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102043	112102043	A	C	112102043	-
NM_000038.6(APC):c.156A>G (p.Gln52=)	324	APC	Uncertain significance	-1	RCV001894506;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102043	112102043	A	G	112102043	-
NM_000038.6(APC):c.158G>T (p.Gly53Val)	324	APC	Uncertain significance	rs772787939	RCV001041181;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102045	112102045	G	T	5:g.112102045G>T	-
NM_000038.6(APC):c.161G>A (p.Ser54Asn)	324	APC	Uncertain significance	rs1756321078	RCV001063732;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102048	112102048	G	A	5:g.112102048G>A	-
NM_000038.6(APC):c.163A>G (p.Ile55Val)	324	APC	Uncertain significance	rs760158426	RCV000564524\|RCV000690193;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102050	112102050	A	G	NC_000005.9:g.112102050A>G	ClinGen:CA028920	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.163_164insG (p.Ile55fs)	324	APC	Pathogenic	rs1554069524	RCV000571383\|RCV001060106;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102050	112102051	A	AG	NC_000005.9:g.112102050_112102051insG	ClinGen:CA658657469	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.164T>C (p.Ile55Thr)	324	APC	Uncertain significance	rs1554069530	RCV000646419;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102051	112102051	T	C	5:g.112102051T>C	ClinGen:CA16021704	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.170_175del (p.Asp57_Glu58del)	324	APC	Uncertain significance	rs1167769425	RCV000773868\|RCV001856071;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102052	112102057	TTGAAGA	T	NC_000005.9:g.112102057_112102062del	-
NM_000038.6(APC):c.165T>A (p.Ile55=)	324	APC	Likely benign	-1	RCV002203853;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102052	112102052	T	A	112102052	-
NM_000038.6(APC):c.168A>G (p.Glu56=)	324	APC	Likely benign	rs1554069532	RCV000568160\|RCV002060444;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102055	112102055	A	G	NC_000005.9:g.112102055A>G	ClinGen:CA445752995	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.168A>C (p.Glu56Asp)	324	APC	Uncertain significance	-1	RCV001981738;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102055	112102055	A	C	112102055	-
NM_000038.6(APC):c.170A>T (p.Asp57Val)	324	APC	Uncertain significance	rs794729227	RCV000184048\|RCV000232299;	N	MONDO:MONDO:0016419,MedGen:C0346153,OMIM:114480, Orphanet:227535\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102057	112102057	A	T	NC_000005.9:g.112102057A>T	ClinGen:CA005471	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.171T>C (p.Asp57=)	324	APC	Likely benign	rs770894012	RCV000205156\|RCV000443847\|RCV000567696;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102058	112102058	T	C	5:g.112102058T>C	ClinGen:CA029139	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.172G>A (p.Glu58Lys)	324	APC	Uncertain significance	-1	RCV001891011;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102059	112102059	G	A	112102059	-
NM_000038.6(APC):c.175G>A (p.Ala59Thr)	324	APC	Uncertain significance	rs1554069536	RCV000573197\|RCV001853820;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102062	112102062	G	A	NC_000005.9:g.112102062G>A	ClinGen:CA16021729	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.176C>G (p.Ala59Gly)	324	APC	Uncertain significance	-1	RCV002027269;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102063	112102063	C	G	112102063	-
NM_000038.6(APC):c.178A>G (p.Met60Val)	324	APC	Uncertain significance	rs1421856417	RCV001187098\|RCV001223712;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102065	112102065	A	G	5:g.112102065A>G	-
NM_000038.6(APC):c.180G>A (p.Met60Ile)	324	APC	Uncertain significance	rs980662480	RCV000646347;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102067	112102067	G	A	NC_000005.9:g.112102067G>A	ClinGen:CA16021741	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.181G>A (p.Ala61Thr)	324	APC	Conflicting interpretations of pathogenicity	rs786201989	RCV000164557\|RCV000646277\|RCV001697165;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112102068	112102068	G	A	5:g.112102068G>A	ClinGen:CA006037	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.181G>C (p.Ala61Pro)	324	APC	Uncertain significance	rs786201989	RCV001013304\|RCV001299090;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102068	112102068	G	C	5:g.112102068G>C	-
NM_000038.6(APC):c.181G>T (p.Ala61Ser)	324	APC	Uncertain significance	rs786201989	RCV001201837;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102068	112102068	G	T	5:g.112102068G>T	-
NM_000038.6(APC):c.184TCT[1] (p.Ser63del)	324	APC	Uncertain significance	rs876660575	RCV000220184\|RCV000646470\|RCV001753679;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112102069	112102071	GCTT	G	5:g.112102069_112102071del	ClinGen:CA10578283	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.184T>C (p.Ser62Pro)	324	APC	Uncertain significance	-1	RCV001967395;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102071	112102071	T	C	112102071	-
NM_000038.6(APC):c.191G>A (p.Gly64Glu)	324	APC	Uncertain significance	rs878853421	RCV000229258\|RCV001854806;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102078	112102078	G	A	5:g.112102078G>A	ClinGen:CA10582273	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.193C>A (p.Gln65Lys)	324	APC	Uncertain significance	rs863225320	RCV000202251\|RCV000587903\|RCV001857742;	N	MedGen:CN169374\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102080	112102080	C	A	NC_000005.9:g.112102080C>A	ClinGen:CA279799	CN517202 not provided;
NM_000038.6(APC):c.194A>G (p.Gln65Arg)	324	APC	Uncertain significance	-1	RCV001993673;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102081	112102081	A	G	112102081	-
NM_000038.6(APC):c.195G>C (p.Gln65His)	324	APC	Uncertain significance	rs1554069548	RCV000590138\|RCV001853964;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102082	112102082	G	C	NC_000005.9:g.112102082G>C	ClinGen:CA16021768	CN517202 not provided;
NM_000038.6(APC):c.195G>A (p.Gln65=)	324	APC	Likely benign	-1	RCV001506948;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102082	112102082	G	A	112102082	-
NM_000038.6(APC):c.196A>G (p.Ile66Val)	324	APC	Uncertain significance	rs764962781	RCV001050298;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102083	112102083	A	G	5:g.112102083A>G	-
NM_000038.6(APC):c.196del (p.Ile66fs)	324	APC	Pathogenic	-1	RCV002007386;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102083	112102083	GA	G	112102082	-
NM_000038.6(APC):c.197T>C (p.Ile66Thr)	324	APC	Uncertain significance	rs1581160506	RCV000797898\|RCV001013942;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102084	112102084	T	C	5:g.112102084T>C	-
NM_000038.6(APC):c.200A>C (p.Asp67Ala)	324	APC	Uncertain significance	-1	RCV001882265;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102087	112102087	A	C	112102087	-
NM_000038.6(APC):c.203del (p.Leu68fs)	324	APC	Pathogenic	rs1756331894	RCV001203172;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102088	112102088	AT	A	5:g.112102088_112102088del	-
NM_000038.6(APC):c.202T>A (p.Leu68Ile)	324	APC	Uncertain significance	rs1756332227	RCV001223915;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102089	112102089	T	A	5:g.112102089T>A	-
NM_000038.6(APC):c.203T>G (p.Leu68Ter)	324	APC	Pathogenic	rs1554069549	RCV000501918\|RCV001851394;	N	MONDO:MONDO:0002032,MedGen:C0699790\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102090	112102090	T	G	NC_000005.9:g.112102090T>G	ClinGen:CA16021788	CN240755 Familial adenomatous polyposis;
NM_000038.6(APC):c.206T>C (p.Leu69Ser)	324	APC	Uncertain significance	-1	RCV001366798\|RCV001776229;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112102093	112102093	T	C	112102093	-
NM_000038.6(APC):c.206T>A (p.Leu69Ter)	324	APC	Pathogenic	-1	RCV001946495;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102093	112102093	T	A	112102093	-
NM_000038.6(APC):c.207A>G (p.Leu69=)	324	APC	Likely benign	rs1554069552	RCV000646623;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102094	112102094	A	G	5:g.112102094A>G	ClinGen:CA445753043	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.209A>G (p.Glu70Gly)	324	APC	Uncertain significance	rs863224539	RCV000197071;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102096	112102096	A	G	NC_000005.9:g.112102096A>G	ClinGen:CA336960	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.210G>A (p.Glu70=)	324	APC	Likely benign	rs761957941	RCV000881851\|RCV001014463\|RCV001454184;	N	MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102097	112102097	G	A	5:g.112102097G>A	-
NM_000038.6(APC):c.211C>A (p.Arg71Ser)	324	APC	Uncertain significance	rs767741687	RCV000467870\|RCV000569830\|RCV000759423\|RCV000779735;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202\|MedGen:CN169374	5	112102098	112102098	C	A	NC_000005.9:g.112102098C>A	ClinGen:CA030831	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.211C>T (p.Arg71Cys)	324	APC	Uncertain significance	rs767741687	RCV000588634\|RCV000823066;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102098	112102098	C	T	NC_000005.9:g.112102098C>T	ClinGen:CA16021805	CN517202 not provided;
NM_000038.6(APC):c.212G>A (p.Arg71His)	324	APC	Uncertain significance	rs750503329	RCV000474741\|RCV000479660\|RCV000571928\|RCV001192982;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	5	112102099	112102099	G	A	NC_000005.9:g.112102099G>A	ClinGen:CA030877	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.212G>T (p.Arg71Leu)	324	APC	Uncertain significance	-1	RCV002000780;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102099	112102099	G	T	112102099	-
NM_000038.6(APC):c.216T>C (p.Leu72=)	324	APC	Likely benign	rs1580324752	RCV000871827\|RCV001014635;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102103	112102103	T	C	5:g.112102103T>C	-
NM_000038.6(APC):c.219del (p.Glu74fs)	324	APC	Pathogenic	rs1756336297	RCV001246797\|RCV001800975;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112102104	112102104	TA	T	5:g.112102104_112102104del	-
NM_000038.6(APC):c.217A>G (p.Lys73Glu)	324	APC	Uncertain significance	-1	RCV001937306;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102104	112102104	A	G	112102104	-
NM_000038.6(APC):c.219A>G (p.Lys73=)	324	APC	Uncertain significance	-1	RCV001759213\|RCV001868711;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102106	112102106	A	G	112102106	-
NM_000038.6(APC):c.220G>T (p.Glu74Ter)	324	APC	Pathogenic/Likely pathogenic	rs876658941	RCV000215333\|RCV000254875\|RCV000459175\|RCV000501460;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0002032,MedGen:C0699790	5	112102107	112102107	G	T	5:g.112102107G>T	ClinGen:CA10578284	CN240755 Familial adenomatous polyposis;
NM_000038.6(APC):c.220G>C (p.Glu74Gln)	324	APC	Uncertain significance	rs876658941	RCV000555556\|RCV001290660;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374	5	112102107	112102107	G	C	5:g.112102107G>C	ClinGen:CA16021823	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.220G>A (p.Glu74Lys)	324	APC	Uncertain significance	rs876658941	RCV000568191\|RCV001858222;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102107	112102107	G	A	5:g.112102107G>A	ClinGen:CA16021822	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.220+1G>A	324	APC	Pathogenic	rs1554069570	RCV000499663;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102108	112102108	G	A	NC_000005.9:g.112102108G>A	ClinGen:CA360617465	CN240755 Familial adenomatous polyposis;
NM_000038.6(APC):c.220+2T>A	324	APC	Pathogenic/Likely pathogenic	rs587781809	RCV000130080\|RCV000202191\|RCV000231290\|RCV000503701;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0002032,MedGen:C0699790	5	112102109	112102109	T	A	5:g.112102109T>A	ClinGen:CA007244	CN240755 Familial adenomatous polyposis;
NM_000038.6(APC):c.220+4G>A	324	APC	Conflicting interpretations of pathogenicity	rs973491846	RCV000582451\|RCV000806431;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102111	112102111	G	A	NC_000005.9:g.112102111G>A	ClinGen:CA124975086	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.220+5A>G	324	APC	Uncertain significance	rs1554069584	RCV000540822;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102112	112102112	A	G	NC_000005.9:g.112102112A>G	ClinGen:CA658657471	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.220+5A>T	324	APC	Uncertain significance	-1	RCV002007069;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102112	112102112	A	T	112102112	-
NM_000038.6(APC):c.220+6T>C	324	APC	Uncertain significance	rs1756339861	RCV001346766;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102113	112102113	T	C	112102113	-
NM_000038.6(APC):c.220+12_220+14del	324	APC	Likely benign	rs864622493	RCV000206367\|RCV001503643;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102117	112102119	TAAA	T	NC_000005.9:g.112102119_112102121del	ClinGen:CA350411	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.220+13A>T	324	APC	Likely benign	-1	RCV002162897;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102120	112102120	A	T	112102120	-
NM_000038.6(APC):c.220+16G>T	324	APC	Likely benign	rs756214797	RCV000776385\|RCV002067328;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102123	112102123	G	T	NC_000005.9:g.112102123G>T	-
NM_000038.6(APC):c.220+16G>C	324	APC	Likely benign	-1	RCV002151073;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102123	112102123	G	C	112102123	-
NM_000038.6(APC):c.220+18G>A	324	APC	Conflicting interpretations of pathogenicity	rs927125994	RCV001178648\|RCV002067892;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102125	112102125	G	A	5:g.112102125G>A	-
NM_000038.6(APC):c.220+19T>C	324	APC	Likely benign	rs754354718	RCV000583115\|RCV002060565;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102126	112102126	T	C	5:g.112102126T>C	ClinGen:CA031007	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.221-16T>C	324	APC	Likely benign	rs1046591128	RCV000410932\|RCV001183272;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102870	112102870	T	C	NC_000005.9:g.112102870T>C	ClinGen:CA16042083	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.221-11A>G	324	APC	Likely benign	rs531060253	RCV000775116\|RCV001720139\|RCV002062485;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102875	112102875	A	G	5:g.112102875A>G	ClinGen:CA16604757	CN169374 not specified;
NM_000038.6(APC):c.221-11A>T	324	APC	Likely benign	rs531060253	RCV000583455\|RCV002060566;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102875	112102875	A	T	5:g.112102875A>T	ClinGen:CA124975587	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.221-5T>C	324	APC	Conflicting interpretations of pathogenicity	rs1057524155	RCV000438575\|RCV000588735\|RCV001078711\|RCV001805053;	N	MedGen:CN169374\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102881	112102881	T	C	5:g.112102881T>C	ClinGen:CA16604759	CN517202 not provided;
NM_000038.6(APC):c.221-5T>G	324	APC	Uncertain significance	rs1057524155	RCV000529587;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102881	112102881	T	G	5:g.112102881T>G	ClinGen:CA658657472	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.221-2A>G	324	APC	Pathogenic/Likely pathogenic	rs786201291	RCV000163246\|RCV000476651\|RCV000480238;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112102884	112102884	A	G	5:g.112102884A>G	ClinGen:CA007277	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.221-2A>T	324	APC	Likely pathogenic	-1	RCV002027646;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102884	112102884	A	T	112102884	-
NM_000038.6(APC):c.221-1G>A	324	APC	Likely pathogenic	rs863225327	RCV000201979\|RCV000491712\|RCV001237158;	N	MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102885	112102885	G	A	NC_000005.9:g.112102885G>A	ClinGen:CA279668	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.221-1G>C	324	APC	Pathogenic/Likely pathogenic	rs863225327	RCV000213314\|RCV000468960;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102885	112102885	G	C	5:g.112102885G>C	ClinGen:CA10578285	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.221A>C (p.Glu74Ala)	324	APC	Conflicting interpretations of pathogenicity	rs773347338	RCV000484103\|RCV000776474\|RCV001079472;	N	MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102886	112102886	A	C	5:g.112102886A>C	ClinGen:CA031365	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.222G>C (p.Glu74Asp)	324	APC	Uncertain significance	rs1561463688	RCV000701528;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102887	112102887	G	C	5:g.112102887G>C	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.222G>T (p.Glu74Asp)	324	APC	Uncertain significance	-1	RCV001968365;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102887	112102887	G	T	112102887	-
NM_000038.6(APC):c.223C>T (p.Leu75Phe)	324	APC	Uncertain significance	rs760790156	RCV000772849\|RCV001856031;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102888	112102888	C	T	NC_000005.9:g.112102888C>T	-
NM_000038.6(APC):c.223C>G (p.Leu75Val)	324	APC	Uncertain significance	rs760790156	RCV000798088;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102888	112102888	C	G	5:g.112102888C>G	-
NM_000038.6(APC):c.224T>C (p.Leu75Pro)	324	APC	Uncertain significance	rs995081817	RCV000532341\|RCV001014931;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102889	112102889	T	C	NC_000005.9:g.112102889T>C	ClinGen:CA16021831	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.226A>C (p.Asn76His)	324	APC	Uncertain significance	rs1756428709	RCV001207321;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102891	112102891	A	C	5:g.112102891A>C	-
NM_000038.6(APC):c.228C>T (p.Asn76=)	324	APC	Likely benign	rs766325173	RCV000198292\|RCV000571232\|RCV001705142\|RCV001824678;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202\|MedGen:CN169374	5	112102893	112102893	C	T	NC_000005.9:g.112102893C>T	ClinGen:CA031634	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.229T>G (p.Leu77Val)	324	APC	Uncertain significance	rs1756429303	RCV001345588;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102894	112102894	T	G	112102894	-
NM_000038.6(APC):c.233_236del (p.Asp78fs)	324	APC	Pathogenic	rs1064793020	RCV000481173\|RCV000492026\|RCV000535814\|RCV001778973;	N	MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021055,MedGen:C0032580,OMIM:PS175100, Orphanet:733	5	112102895	112102898	TTAGA	T	NC_000005.9:g.112102898_112102901del	ClinGen:CA16618066	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.230T>A (p.Leu77Ter)	324	APC	Pathogenic	-1	RCV001358256;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102895	112102895	T	A	112102895	-
NM_000038.6(APC):c.231A>G (p.Leu77=)	324	APC	Likely benign	-1	RCV001403077;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102896	112102896	A	G	112102896	-
NM_000038.6(APC):c.232G>A (p.Asp78Asn)	324	APC	Uncertain significance	rs1253209514	RCV001015210\|RCV001224283;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102897	112102897	G	A	5:g.112102897G>A	-
NM_000038.6(APC):c.233A>C (p.Asp78Ala)	324	APC	Uncertain significance	rs562833260	RCV000573725\|RCV000646512;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102898	112102898	A	C	5:g.112102898A>C	ClinGen:CA031709	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.235A>G (p.Ser79Gly)	324	APC	Uncertain significance	rs1001856924	RCV000773537\|RCV001223504;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102900	112102900	A	G	NC_000005.9:g.112102900A>G	-
NM_000038.6(APC):c.235A>C (p.Ser79Arg)	324	APC	Uncertain significance	-1	RCV002046640;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102900	112102900	A	C	112102900	-
NM_000038.6(APC):c.236G>A (p.Ser79Asn)	324	APC	Uncertain significance	rs1554069689	RCV000646481;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102901	112102901	G	A	5:g.112102901G>A	ClinGen:CA16021858	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.239G>C (p.Ser80Thr)	324	APC	Uncertain significance	rs876659390	RCV000222538\|RCV001294854;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102904	112102904	G	C	5:g.112102904G>C	ClinGen:CA10578286	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.239G>A (p.Ser80Asn)	324	APC	Uncertain significance	rs876659390	RCV000807142;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102904	112102904	G	A	5:g.112102904G>A	-
NM_000038.6(APC):c.244T>A (p.Phe82Ile)	324	APC	Uncertain significance	rs863225329	RCV000201969\|RCV001853249;	N	MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102909	112102909	T	A	NC_000005.9:g.112102909T>A	ClinGen:CA279662	CN169374 not specified;
NM_000038.6(APC):c.244T>C (p.Phe82Leu)	324	APC	Uncertain significance	rs863225329	RCV001323108;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102909	112102909	T	C	112102909	-
NM_000038.6(APC):c.245T>C (p.Phe82Ser)	324	APC	Uncertain significance	rs1179254201	RCV000569708\|RCV000700319\|RCV001293968;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:C1851124,OMIM:135290, Orphanet:873	5	112102910	112102910	T	C	5:g.112102910T>C	ClinGen:CA16021881	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.246C>T (p.Phe82=)	324	APC	Likely benign	-1	RCV002078374;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102911	112102911	C	T	112102911	-
NM_000038.6(APC):c.248C>T (p.Pro83Leu)	324	APC	Uncertain significance	rs1163661746	RCV001044495;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102913	112102913	C	T	5:g.112102913C>T	-
NM_000038.6(APC):c.248C>G (p.Pro83Arg)	324	APC	Uncertain significance	-1	RCV001989256;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102913	112102913	C	G	112102913	-
NM_000038.6(APC):c.249del (p.Gly84fs)	324	APC	Pathogenic	rs878853428	RCV000232213\|RCV000657492;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112102914	112102914	CT	C	NC_000005.9:g.112102914del	ClinGen:CA10582274	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.249T>G (p.Pro83=)	324	APC	Likely benign	-1	RCV002217592;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102914	112102914	T	G	112102914	-
NM_000038.6(APC):c.250G>C (p.Gly84Arg)	324	APC	Uncertain significance	-1	RCV001974318;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102915	112102915	G	C	112102915	-
NM_000038.6(APC):c.251G>T (p.Gly84Val)	324	APC	Uncertain significance	rs143145868	RCV000220182\|RCV000823918;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102916	112102916	G	T	NC_000005.9:g.112102916G>T	ClinGen:CA032367	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.252A>G (p.Gly84=)	324	APC	Likely benign	rs375051600	RCV001015846\|RCV002068921;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102917	112102917	A	G	5:g.112102917A>G	-
NM_000038.6(APC):c.254del (p.Val85fs)	324	APC	Pathogenic	-1	RCV001949573;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102919	112102919	GT	G	112102918	-
NM_000038.6(APC):c.259C>T (p.Leu87=)	324	APC	Benign/Likely benign	rs569640184	RCV000122765\|RCV000163523\|RCV001079418;	N	MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102924	112102924	C	T	NC_000005.9:g.112102924C>T	ClinGen:CA007647	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.260T>C (p.Leu87Pro)	324	APC	Uncertain significance	rs777456713	RCV000558893;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102925	112102925	T	C	5:g.112102925T>C	ClinGen:CA16021913	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.260T>G (p.Leu87Arg)	324	APC	Uncertain significance	rs777456713	RCV001045894;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102925	112102925	T	G	5:g.112102925T>G	-
NM_000038.6(APC):c.262C>T (p.Arg88Trp)	324	APC	Uncertain significance	rs746592911	RCV000484135\|RCV000574492\|RCV000646444\|RCV000766533;	N	MONDO:MONDO:0002032,MedGen:C0699790\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112102927	112102927	C	T	5:g.112102927C>T	ClinGen:CA032840	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.263G>A (p.Arg88Gln)	324	APC	Uncertain significance	rs587780592	RCV000122766\|RCV000413883\|RCV000566722;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102928	112102928	G	A	NC_000005.9:g.112102928G>A	ClinGen:CA007680	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.263G>T (p.Arg88Leu)	324	APC	Uncertain significance	rs587780592	RCV001016167\|RCV001057069;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102928	112102928	G	T	5:g.112102928G>T	-
NM_000038.6(APC):c.264G>A (p.Arg88=)	324	APC	Likely benign	rs1554069706	RCV000646591\|RCV001016208;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102929	112102929	G	A	5:g.112102929G>A	ClinGen:CA445753164	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.266C>G (p.Ser89Ter)	324	APC	Pathogenic	rs876658846	RCV000221332\|RCV000767384;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102931	112102931	C	G	5:g.112102931C>G	ClinGen:CA10578287	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.266C>A (p.Ser89Ter)	324	APC	Pathogenic	rs876658846	RCV000686347\|RCV001016260;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102931	112102931	C	A	5:g.112102931C>A	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.280_281insTGGAGGAAATTGGACACCATCATTCTCAGTAAACTATCGCACGAACAAAAAACCAAACACCGCATCGTCTC	324	APC	Pathogenic	-1	RCV001951264;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102931	112102932	C	CAAAAATGTCCCTCCTGGAGGAAATTGGACACCATCATTCTCAGTAAACTATCGCACGAACAAAAAACCAAACACCGCATCGTCTCAGTCNNNNNNNNNNAAAAAAAAAA	112102931	-
NM_000038.6(APC):c.268A>G (p.Lys90Glu)	324	APC	Uncertain significance	rs763184444	RCV000201975\|RCV000528829\|RCV000580141\|RCV001550070;	N	MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202	5	112102933	112102933	A	G	NC_000005.9:g.112102933A>G	ClinGen:CA033035	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.272T>C (p.Met91Thr)	324	APC	Uncertain significance	-1	RCV001888347;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102937	112102937	T	C	112102937	-
NM_000038.6(APC):c.273G>A (p.Met91Ile)	324	APC	Uncertain significance	rs745394881	RCV000775117\|RCV000819063;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102938	112102938	G	A	NC_000005.9:g.112102938G>A	-
NM_000038.6(APC):c.274T>G (p.Ser92Ala)	324	APC	Uncertain significance	rs1554069716	RCV000646366\|RCV001016496;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102939	112102939	T	G	NC_000005.9:g.112102939T>G	ClinGen:CA16021939	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.275C>G (p.Ser92Cys)	324	APC	Uncertain significance	rs769708176	RCV000685926\|RCV001016520;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102940	112102940	C	G	5:g.112102940C>G	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.276C>T (p.Ser92=)	324	APC	Likely benign	rs369238363	RCV000200217\|RCV000569741\|RCV001532995;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	5	112102941	112102941	C	T	NC_000005.9:g.112102941C>T	ClinGen:CA033380	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.276C>G (p.Ser92=)	324	APC	Likely benign	-1	RCV001453240;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102941	112102941	C	G	112102941	-
NM_000038.6(APC):c.277C>G (p.Leu93Val)	324	APC	Conflicting interpretations of pathogenicity	rs201567345	RCV000233150\|RCV000491761\|RCV000657055\|RCV001818550;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202\|MedGen:CN169374	5	112102942	112102942	C	G	NC_000005.9:g.112102942C>G	ClinGen:CA033407	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.277C>T (p.Leu93Phe)	324	APC	Uncertain significance	rs201567345	RCV001016583\|RCV001067244;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102942	112102942	C	T	5:g.112102942C>T	-
NM_000038.6(APC):c.278T>A (p.Leu93His)	324	APC	Uncertain significance	rs876658977	RCV000217948\|RCV000700668;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102943	112102943	T	A	5:g.112102943T>A	ClinGen:CA10578288	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.279C>T (p.Leu93=)	324	APC	Likely benign	rs768492450	RCV000565354\|RCV001483090;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102944	112102944	C	T	5:g.112102944C>T	ClinGen:CA445753227	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.280C>G (p.Arg94Gly)	324	APC	Uncertain significance	rs550945533	RCV000221637\|RCV000700669;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102945	112102945	C	G	5:g.112102945C>G	ClinGen:CA10578289	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.280C>A (p.Arg94Ser)	324	APC	Uncertain significance	rs550945533	RCV000409081\|RCV001016652\|RCV001775785;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202	5	112102945	112102945	C	A	NC_000005.9:g.112102945C>A	ClinGen:CA16021946	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.280C>T (p.Arg94Cys)	324	APC	Uncertain significance	rs550945533	RCV000563719\|RCV001364425;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102945	112102945	C	T	5:g.112102945C>T	ClinGen:CA16021947	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.281G>A (p.Arg94His)	324	APC	Uncertain significance	rs774229223	RCV000581085\|RCV000646341;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102946	112102946	G	A	5:g.112102946G>A	ClinGen:CA033585	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.281_282del (p.Arg94fs)	324	APC	Likely pathogenic	rs1561464190	RCV000755038;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102946	112102947	CGT	C	NC_000005.9:g.112102946_112102947del	-
NM_000038.6(APC):c.281G>C (p.Arg94Pro)	324	APC	Uncertain significance	-1	RCV002019142;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102946	112102946	G	C	112102946	-
NM_000038.6(APC):c.282T>C (p.Arg94=)	324	APC	Likely benign	rs1485825595	RCV000776852\|RCV002061110;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102947	112102947	T	C	NC_000005.9:g.112102947T>C	-
NM_000038.6(APC):c.284C>T (p.Ser95Phe)	324	APC	Uncertain significance	rs146221748	RCV000574779\|RCV000797167\|RCV001764656;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112102949	112102949	C	T	NC_000005.9:g.112102949C>T	ClinGen:CA16021955	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.287A>G (p.Tyr96Cys)	324	APC	Uncertain significance	rs760770847	RCV000580580\|RCV001860022;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102952	112102952	A	G	5:g.112102952A>G	ClinGen:CA033841	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.287A>T (p.Tyr96Phe)	324	APC	Uncertain significance	rs760770847	RCV000694205\|RCV001016872;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102952	112102952	A	T	5:g.112102952A>T	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.288T>A (p.Tyr96Ter)	324	APC	Pathogenic	rs376213437	RCV000159585\|RCV000540671\|RCV001016886;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102953	112102953	T	A	NC_000005.9:g.112102953T>A	ClinGen:CA007872	CN240755 Familial adenomatous polyposis;
NM_000038.6(APC):c.288T>C (p.Tyr96=)	324	APC	Benign/Likely benign	rs376213437	RCV000165334\|RCV000205434\|RCV000427257\|RCV001704202;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374\|MedGen:CN517202	5	112102953	112102953	T	C	5:g.112102953T>C	ClinGen:CA007882	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.288T>G (p.Tyr96Ter)	324	APC	Pathogenic	rs376213437	RCV000202141\|RCV000491545\|RCV000555518;	N	MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102953	112102953	T	G	NC_000005.9:g.112102953T>G	ClinGen:CA248534	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.295C>T (p.Arg99Trp)	324	APC	Conflicting interpretations of pathogenicity	rs139196838	RCV000122769\|RCV000129141\|RCV000200967\|RCV000210128\|RCV000589216\|RCV001353757\|RCV001762272;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374\|MedGen:C1858438\|MedGen:CN517202\|MONDO:MONDO:0002032,MedGen:C0699790\|MONDO:MONDO:0005575,MedGen:C0346629,OMIM:114500	5	112102960	112102960	C	T	NC_000005.9:g.112102960C>T	ClinGen:CA007948,UniProtKB:P25054#VAR_009613	C1858438 Colorectal cancer, susceptibility to;
NM_000038.6(APC):c.295C>A (p.Arg99=)	324	APC	Uncertain significance	rs139196838	RCV000553655;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102960	112102960	C	A	NC_000005.9:g.112102960C>A	ClinGen:CA445753285	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.296G>A (p.Arg99Gln)	324	APC	Uncertain significance	rs199842850	RCV000197478\|RCV000491566\|RCV000585993;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202	5	112102961	112102961	G	A	NC_000005.9:g.112102961G>A	ClinGen:CA007959	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.298del (p.Glu100fs)	324	APC	Pathogenic/Likely pathogenic	rs1064794224	RCV000486524\|RCV000646505;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102961	112102961	CG	C	NC_000005.9:g.112102963del	ClinGen:CA16618067	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.297G>T (p.Arg99=)	324	APC	Likely benign	rs765804855	RCV000935972\|RCV001187112\|RCV001500145;	N	MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102962	112102962	G	T	5:g.112102962G>T	-
NM_000038.6(APC):c.298G>A (p.Glu100Lys)	324	APC	Uncertain significance	rs1561464319	RCV000707121;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102963	112102963	G	A	NC_000005.9:g.112102963G>A	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.301_303dup (p.Gly101dup)	324	APC	Uncertain significance	-1	RCV001865028;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102964	112102965	A	AAGG	112102964	-
NM_000038.6(APC):c.300A>G (p.Glu100=)	324	APC	Likely benign	rs1060504888	RCV000473825;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102965	112102965	A	G	NC_000005.9:g.112102965A>G	ClinGen:CA16611637	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.301G>T (p.Gly101Ter)	324	APC	Pathogenic	rs863225335	RCV000202070\|RCV000570097\|RCV001853250;	N	MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102966	112102966	G	T	NC_000005.9:g.112102966G>T	ClinGen:CA279710	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.302G>A (p.Gly101Glu)	324	APC	Uncertain significance	rs954713888	RCV000708949;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102967	112102967	G	A	NC_000005.9:g.112102967G>A	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.302G>C (p.Gly101Ala)	324	APC	Uncertain significance	rs954713888	RCV001018186\|RCV001035615;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102967	112102967	G	C	5:g.112102967G>C	-
NM_000038.6(APC):c.303A>G (p.Gly101=)	324	APC	Uncertain significance	rs1756452016	RCV001203136;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102968	112102968	A	G	5:g.112102968A>G	-
NM_000038.6(APC):c.304T>C (p.Ser102Pro)	324	APC	Uncertain significance	rs753302494	RCV000561562\|RCV001215583;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102969	112102969	T	C	5:g.112102969T>C	ClinGen:CA034347	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.305C>G (p.Ser102Cys)	324	APC	Uncertain significance	-1	RCV001883382;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102970	112102970	C	G	112102970	-
NM_000038.6(APC):c.307G>C (p.Val103Leu)	324	APC	Uncertain significance	rs758995578	RCV000469391;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102972	112102972	G	C	NC_000005.9:g.112102972G>C	ClinGen:CA16021996	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.307G>T (p.Val103Leu)	324	APC	Uncertain significance	rs758995578	RCV000571583\|RCV001867873;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102972	112102972	G	T	5:g.112102972G>T	ClinGen:CA16021997	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.309A>G (p.Val103=)	324	APC	Likely benign	rs863224279	RCV000195995\|RCV001018605\|RCV001500054;	N	MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102974	112102974	A	G	5:g.112102974A>G	ClinGen:CA336102	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.311C>G (p.Ser104Ter)	324	APC	Pathogenic/Likely pathogenic	rs74953290	RCV000213087\|RCV000506152\|RCV000519665\|RCV001254064\|RCV001853550;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102976	112102976	C	G	5:g.112102976C>G	ClinGen:CA10578290	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.311C>T (p.Ser104Leu)	324	APC	Uncertain significance	rs74953290	RCV000691711;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102976	112102976	C	T	5:g.112102976C>T	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.313A>G (p.Ser105Gly)	324	APC	Uncertain significance	rs776242276	RCV000562645\|RCV000646333;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102978	112102978	A	G	5:g.112102978A>G	ClinGen:CA16022006	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.314G>A (p.Ser105Asn)	324	APC	Uncertain significance	rs1580328726	RCV000815337\|RCV001796248;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112102979	112102979	G	A	5:g.112102979G>A	-
NM_000038.6(APC):c.316C>T (p.Arg106Cys)	324	APC	Uncertain significance	rs1554069763	RCV000555181\|RCV001018945;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102981	112102981	C	T	NC_000005.9:g.112102981C>T	ClinGen:CA16022015	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.317G>A (p.Arg106His)	324	APC	Uncertain significance	rs201764637	RCV000034409\|RCV000410470\|RCV000455267\|RCV000565565\|RCV000659270;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021055,MedGen:C0032580,OMIM:PS175100, Orphanet:733	5	112102982	112102982	G	A	5:g.112102982G>A	ClinGen:CA008128	CN240755 Familial adenomatous polyposis;
NM_000038.6(APC):c.317G>T (p.Arg106Leu)	324	APC	Uncertain significance	rs201764637	RCV001019017\|RCV001035384;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102982	112102982	G	T	5:g.112102982G>T	-
NM_000038.6(APC):c.319T>G (p.Ser107Ala)	324	APC	Uncertain significance	rs1485866385	RCV000821613\|RCV001019146;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102984	112102984	T	G	NC_000005.9:g.112102984T>G	-
NM_000038.6(APC):c.320C>G (p.Ser107Cys)	324	APC	Uncertain significance	rs774416950	RCV000777304\|RCV001873166;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102985	112102985	C	G	NC_000005.9:g.112102985C>G	-
NM_000038.6(APC):c.321T>C (p.Ser107=)	324	APC	Likely benign	-1	RCV001484474;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102986	112102986	T	C	112102986	-
NM_000038.6(APC):c.322G>T (p.Gly108Ter)	324	APC	Pathogenic	-1	RCV001930377;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102987	112102987	G	T	112102987	-
NM_000038.6(APC):c.323G>A (p.Gly108Glu)	324	APC	Conflicting interpretations of pathogenicity	rs1114167456	RCV000491472\|RCV000775971\|RCV001051832;	N	MedGen:C1858438\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102988	112102988	G	A	NC_000005.9:g.112102988G>A	ClinGen:CA16022027	C1858438 Colorectal cancer, susceptibility to;
NM_000038.6(APC):c.326A>G (p.Glu109Gly)	324	APC	Uncertain significance	rs1756458773	RCV001239077;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102991	112102991	A	G	5:g.112102991A>G	-
NM_000038.6(APC):c.328T>C (p.Cys110Arg)	324	APC	Uncertain significance	rs751956779	RCV000692270;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102993	112102993	T	C	NC_000005.9:g.112102993T>C	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.330C>T (p.Cys110=)	324	APC	Likely benign	rs1060504887	RCV000463523\|RCV000568079;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102995	112102995	C	T	NC_000005.9:g.112102995C>T	ClinGen:CA16611601	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.331A>G (p.Ser111Gly)	324	APC	Uncertain significance	rs1580328938	RCV000987549\|RCV001184638;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102996	112102996	A	G	5:g.112102996A>G	-
NM_000038.6(APC):c.332G>A (p.Ser111Asn)	324	APC	Uncertain significance	rs786202322	RCV000165072\|RCV000233865\|RCV001582652;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112102997	112102997	G	A	5:g.112102997G>A	ClinGen:CA008281	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.334C>A (p.Pro112Thr)	324	APC	Uncertain significance	rs1392982680	RCV000813105\|RCV001805888;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112102999	112102999	C	A	5:g.112102999C>A	-
NM_000038.6(APC):c.334C>T (p.Pro112Ser)	324	APC	Uncertain significance	rs1392982680	RCV001338998;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112102999	112102999	C	T	112102999	-
NM_000038.6(APC):c.335C>G (p.Pro112Arg)	324	APC	Uncertain significance	rs1060503357	RCV000461562\|RCV001020080\|RCV001770356;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202	5	112103000	112103000	C	G	NC_000005.9:g.112103000C>G	ClinGen:CA16022055	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.338T>C (p.Val113Ala)	324	APC	Uncertain significance	rs863224542	RCV000200174;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103003	112103003	T	C	NC_000005.9:g.112103003T>C	ClinGen:CA339132	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.340C>A (p.Pro114Thr)	324	APC	Uncertain significance	rs1580329044	RCV001020227\|RCV001860976;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103005	112103005	C	A	5:g.112103005C>A	-
NM_000038.6(APC):c.340C>T (p.Pro114Ser)	324	APC	Uncertain significance	-1	RCV001916640;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103005	112103005	C	T	112103005	-
NM_000038.6(APC):c.341C>G (p.Pro114Arg)	324	APC	Uncertain significance	rs200117298	RCV001056165\|RCV001796358;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112103006	112103006	C	G	5:g.112103006C>G	-
NM_000038.6(APC):c.341C>T (p.Pro114Leu)	324	APC	Uncertain significance	rs200117298	RCV001182823\|RCV001344828;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103006	112103006	C	T	5:g.112103006C>T	-
NM_000038.6(APC):c.343A>G (p.Met115Val)	324	APC	Uncertain significance	rs1060503276	RCV000471223\|RCV000566474\|RCV000985295;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202	5	112103008	112103008	A	G	5:g.112103008A>G	ClinGen:CA16022069	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.344T>A (p.Met115Lys)	324	APC	Uncertain significance	rs1756462909	RCV001341029;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103009	112103009	T	A	112103009	-
NM_000038.6(APC):c.346G>C (p.Gly116Arg)	324	APC	Uncertain significance	rs142637152	RCV001039243;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103011	112103011	G	C	5:g.112103011G>C	-
NM_000038.6(APC):c.347G>A (p.Gly116Asp)	324	APC	Uncertain significance	rs369999291	RCV000581664\|RCV000646298;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103012	112103012	G	A	NC_000005.9:g.112103012G>A	ClinGen:CA16022080	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.350C>A (p.Ser117Ter)	324	APC	Pathogenic	rs1064793535	RCV000482015\|RCV000561431\|RCV000646504\|RCV001824795;	N	MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021055,MedGen:C0032580,OMIM:PS175100, Orphanet:733	5	112103015	112103015	C	A	5:g.112103015C>A	ClinGen:CA16022086	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.351A>C (p.Ser117=)	324	APC	Likely benign	rs1294902871	RCV000982897\|RCV001431511;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103016	112103016	A	C	5:g.112103016A>C	-
NM_000038.6(APC):c.353T>G (p.Phe118Cys)	324	APC	Uncertain significance	rs1756464913	RCV001323140;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103018	112103018	T	G	112103018	-
NM_000038.6(APC):c.356C>T (p.Pro119Leu)	324	APC	Uncertain significance	-1	RCV001979394;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103021	112103021	C	T	112103021	-
NM_000038.6(APC):c.357A>G (p.Pro119=)	324	APC	Likely benign	rs1306334779	RCV001020648\|RCV001394163;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103022	112103022	A	G	5:g.112103022A>G	-
NM_000038.6(APC):c.358A>G (p.Arg120Gly)	324	APC	Uncertain significance	rs876659470	RCV000561323\|RCV000679056\|RCV001192979\|RCV001304515;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202\|MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103023	112103023	A	G	5:g.112103023A>G	ClinGen:CA16022103	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.362G>T (p.Arg121Ile)	324	APC	Uncertain significance	rs193049694	RCV000205797\|RCV000570345;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112103027	112103027	G	T	NC_000005.9:g.112103027G>T	ClinGen:CA036020	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.362G>A (p.Arg121Lys)	324	APC	Uncertain significance	rs193049694	RCV001065793\|RCV001186320;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112103027	112103027	G	A	5:g.112103027G>A	-
NM_000038.6(APC):c.362G>C (p.Arg121Thr)	324	APC	Uncertain significance	-1	RCV001366825;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103027	112103027	G	C	112103027	-
NM_000038.6(APC):c.366del (p.Phe123fs)	324	APC	Pathogenic	rs1580329260	RCV000815470;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103029	112103029	AG	A	5:g.112103029_112103029del	-
NM_000038.6(APC):c.364G>A (p.Gly122Arg)	324	APC	Uncertain significance	-1	RCV001887567;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103029	112103029	G	A	112103029	-
NM_000038.6(APC):c.365G>T (p.Gly122Val)	324	APC	Uncertain significance	rs755660899	RCV000575451\|RCV000802382\|RCV001815415;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112103030	112103030	G	T	NC_000005.9:g.112103030G>T	ClinGen:CA036174	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.365G>C (p.Gly122Ala)	324	APC	Uncertain significance	rs755660899	RCV000803977\|RCV001020823;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112103030	112103030	G	C	5:g.112103030G>C	-
NM_000038.6(APC):c.367T>A (p.Phe123Ile)	324	APC	Uncertain significance	rs1756467769	RCV001226859;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103032	112103032	T	A	5:g.112103032T>A	-
NM_000038.6(APC):c.369_422+44delinsG	324	APC	Likely pathogenic	-1	RCV002005193;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103034	112103131	TGTAAATGGAAGCAGAGAAAGTACTGGATATTTAGAAGAACTTGAGAAAGAGAGGTAACTTTTCTTCATATAGTAAACATTGCCTTGTGTACTCCAGT	G	112103034	-
NM_000038.6(APC):c.370G>A (p.Val124Ile)	324	APC	Uncertain significance	rs779945112	RCV000464404;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103035	112103035	G	A	NC_000005.9:g.112103035G>A	ClinGen:CA16022128	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.370G>C (p.Val124Leu)	324	APC	Uncertain significance	-1	RCV002028242;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103035	112103035	G	C	112103035	-
NM_000038.6(APC):c.372A>G (p.Val124=)	324	APC	Likely benign	rs749179034	RCV000166670\|RCV000555868\|RCV000608108\|RCV001800502;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374\|MedGen:CN517202	5	112103037	112103037	A	G	5:g.112103037A>G	ClinGen:CA008642	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.374A>G (p.Asn125Ser)	324	APC	Uncertain significance	-1	RCV001366438;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103039	112103039	A	G	112103039	-
NM_000038.6(APC):c.375T>C (p.Asn125=)	324	APC	Likely benign	rs768615558	RCV001021070\|RCV001420042;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103040	112103040	T	C	5:g.112103040T>C	-
NM_000038.6(APC):c.381_406del (p.Ser127fs)	324	APC	Pathogenic	-1	RCV001913691;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103042	112103067	GGAAGCAGAGAAAGTACTGGATATTTA	G	112103041	-
NM_000038.6(APC):c.378A>G (p.Gly126=)	324	APC	Likely benign	-1	RCV002158496;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103043	112103043	A	G	112103043	-
NM_000038.6(APC):c.379A>G (p.Ser127Gly)	324	APC	Uncertain significance	rs200089324	RCV000034386\|RCV000167102\|RCV000410052;	N	MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103044	112103044	A	G	5:g.112103044A>G	ClinGen:CA008675	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.380G>A (p.Ser127Asn)	324	APC	Uncertain significance	rs1414642619	RCV000688983\|RCV001021205;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112103045	112103045	G	A	5:g.112103045G>A	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.383G>C (p.Arg128Thr)	324	APC	Uncertain significance	rs1756470431	RCV001313625;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103048	112103048	G	C	112103048	-
NM_000038.6(APC):c.384A>G (p.Arg128=)	324	APC	Conflicting interpretations of pathogenicity	rs876659284	RCV000213500\|RCV000484255\|RCV001454760;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103049	112103049	A	G	5:g.112103049A>G	ClinGen:CA10578292	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.385G>C (p.Glu129Gln)	324	APC	Conflicting interpretations of pathogenicity	rs376628500	RCV000120050\|RCV000196705\|RCV000216893\|RCV000589545;	N	MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202	5	112103050	112103050	G	C	5:g.112103050G>C	ClinGen:CA008713	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.388del (p.Ser130fs)	324	APC	Likely pathogenic	rs1554069828	RCV000662861;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103051	112103051	GA	G	5:g.112103051_112103051del	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.386A>G (p.Glu129Gly)	324	APC	Uncertain significance	rs759662717	RCV000817746\|RCV001191301;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112103051	112103051	A	G	5:g.112103051A>G	-
NM_000038.6(APC):c.386A>T (p.Glu129Val)	324	APC	Uncertain significance	-1	RCV001969388;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103051	112103051	A	T	112103051	-
NM_000038.6(APC):c.387A>G (p.Glu129=)	324	APC	Likely benign	rs1554069832	RCV000573413\|RCV000924570\|RCV001453390;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103052	112103052	A	G	5:g.112103052A>G	ClinGen:CA445753410	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.387A>C (p.Glu129Asp)	324	APC	Uncertain significance	-1	RCV001937657;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103052	112103052	A	C	112103052	-
NM_000038.6(APC):c.388A>G (p.Ser130Gly)	324	APC	Conflicting interpretations of pathogenicity	rs150973053	RCV000034387\|RCV000122775\|RCV000129715\|RCV000211891\|RCV000417265\|RCV001155264\|RCV001762081;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374\|MONDO:MONDO:0021055,MedGen:C0032580,OMIM:PS175100, Orphanet:733\|MedGen:CN239210\|MONDO:MONDO:0005575,MedGen:C0	5	112103053	112103053	A	G	5:g.112103053A>G	ClinGen:CA008731	CN240755 Familial adenomatous polyposis;
NM_000038.6(APC):c.392C>G (p.Thr131Ser)	324	APC	Uncertain significance	rs1387998721	RCV000571547\|RCV000646355;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103057	112103057	C	G	5:g.112103057C>G	ClinGen:CA16022176	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.392C>T (p.Thr131Ile)	324	APC	Uncertain significance	rs1387998721	RCV001301535;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103057	112103057	C	T	112103057	-
NM_000038.6(APC):c.393T>C (p.Thr131=)	324	APC	Likely benign	rs775742850	RCV000163863\|RCV000548080;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103058	112103058	T	C	5:g.112103058T>C	ClinGen:CA008809	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.394G>A (p.Gly132Arg)	324	APC	Uncertain significance	rs1580329638	RCV001021500\|RCV001050218;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103059	112103059	G	A	5:g.112103059G>A	-
NM_000038.6(APC):c.396A>C (p.Gly132=)	324	APC	Likely benign	rs1060504884	RCV000475145\|RCV001402755;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103061	112103061	A	C	NC_000005.9:g.112103061A>C	ClinGen:CA16611554	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.397T>G (p.Tyr133Asp)	324	APC	Uncertain significance	rs763487503	RCV000415652;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103062	112103062	T	G	5:g.112103062T>G	ClinGen:CA037250	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.398A>G (p.Tyr133Cys)	324	APC	Uncertain significance	rs1561465075	RCV000774003\|RCV001856075;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103063	112103063	A	G	NC_000005.9:g.112103063A>G	-
NM_000038.6(APC):c.403GAA[1] (p.Glu136del)	324	APC	Uncertain significance	-1	RCV001976118;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103067	112103069	TAGA	T	112103066	-
NM_000038.6(APC):c.403_404insTT (p.Glu135fs)	324	APC	Pathogenic	rs1756475997	RCV001244359;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103068	112103069	G	GTT	5:g.112103068_112103069insTT	-
NM_000038.6(APC):c.405A>G (p.Glu135=)	324	APC	Likely benign	rs1554069842	RCV000524997;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103070	112103070	A	G	NC_000005.9:g.112103070A>G	ClinGen:CA445753429	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.410T>G (p.Leu137Arg)	324	APC	Uncertain significance	rs1756476556	RCV001234899;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103075	112103075	T	G	5:g.112103075T>G	-
NM_000038.6(APC):c.413A>C (p.Glu138Ala)	324	APC	Uncertain significance	-1	RCV001933097;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103078	112103078	A	C	112103078	-
NM_000038.6(APC):c.414G>A (p.Glu138=)	324	APC	Likely benign	rs1554069845	RCV000563602\|RCV000933345\|RCV001466729;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103079	112103079	G	A	5:g.112103079G>A	ClinGen:CA445753437	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.421_422del (p.Arg141fs)	324	APC	Pathogenic	rs1554069850	RCV000534073\|RCV000657261\|RCV001022064;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112103082	112103083	AAG	A	NC_000005.9:g.112103082AG[2]	ClinGen:CA645546024	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.417A>G (p.Lys139=)	324	APC	Likely benign	rs1554069848	RCV000561844\|RCV000875392\|RCV001392168\|RCV001420741;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374	5	112103082	112103082	A	G	5:g.112103082A>G	ClinGen:CA445753442	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.419A>C (p.Glu140Ala)	324	APC	Uncertain significance	-1	RCV001367542;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103084	112103084	A	C	112103084	-
NM_000038.6(APC):c.420G>C (p.Glu140Asp)	324	APC	Uncertain significance	rs202161017	RCV000034414\|RCV000409727\|RCV000579781;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112103085	112103085	G	C	5:g.112103085G>C	ClinGen:CA008951	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.421A>C (p.Arg141=)	324	APC	Uncertain significance	rs1561465195	RCV000798848\|RCV001177511;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112103086	112103086	A	C	5:g.112103086A>C	-
NM_000038.6(APC):c.421A>G (p.Arg141Gly)	324	APC	Uncertain significance	rs1561465195	RCV001068104;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103086	112103086	A	G	5:g.112103086A>G	-
NM_000038.6(APC):c.422G>C (p.Arg141Thr)	324	APC	Uncertain significance	-1	RCV001365090;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103087	112103087	G	C	112103087	-
NM_000038.6(APC):c.422+1G>C	324	APC	Likely pathogenic	-1	RCV001378009;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103088	112103088	G	C	112103088	-
NM_000038.6(APC):c.422+2T>C	324	APC	Likely pathogenic	rs879254169	RCV000235994\|RCV000411017;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103089	112103089	T	C	NC_000005.9:g.112103089T>C	ClinGen:CA10584235	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.422+2T>G	324	APC	Likely pathogenic	rs879254169	RCV000494112\|RCV000812496;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103089	112103089	T	G	NC_000005.9:g.112103089T>G	ClinGen:CA360617477	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.422+3A>G	324	APC	Uncertain significance	rs1561465237	RCV000773149\|RCV001348775;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103090	112103090	A	G	NC_000005.9:g.112103090A>G	-
NM_000038.6(APC):c.422+6T>C	324	APC	Uncertain significance	rs864622442	RCV000205347;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103093	112103093	T	C	NC_000005.9:g.112103093T>C	ClinGen:CA349506	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.422+6T>G	324	APC	Uncertain significance	rs864622442	RCV001223905;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103093	112103093	T	G	5:g.112103093T>G	-
NM_000038.6(APC):c.422+10C>T	324	APC	Likely benign	rs899376835	RCV000583391\|RCV000865896;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103097	112103097	C	T	5:g.112103097C>T	ClinGen:CA124975734	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.422+10C>G	324	APC	Likely benign	-1	RCV002150930;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103097	112103097	C	G	112103097	-
NM_000038.6(APC):c.422+11T>C	324	APC	Likely benign	-1	RCV002169146;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103098	112103098	T	C	112103098	-
NM_000038.6(APC):c.422+14A>G	324	APC	Likely benign	-1	RCV002125367;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103101	112103101	A	G	112103101	-
NM_000038.6(APC):c.422+18A>G	324	APC	Likely benign	-1	RCV002129338;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112103105	112103105	A	G	112103105	-
NM_000038.6(APC):c.422+19G>C	324	APC	Likely benign	rs767046355	RCV000411339\|RCV000442743\|RCV000775119;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112103106	112103106	G	C	NC_000005.9:g.112103106G>C	ClinGen:CA038094	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.423-28G>T	324	APC	Likely benign	rs570467572	RCV000410109;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111298	112111298	G	T	NC_000005.9:g.112111298G>T	ClinGen:CA16042084	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.423-17T>A	324	APC	Benign/Likely benign	rs534684461	RCV000202107\|RCV000582266\|RCV000987551\|RCV001640304;	N	MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112111309	112111309	T	A	5:g.112111309T>A	ClinGen:CA210397	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.423-4dup	324	APC	Benign	rs730881230	RCV000987550\|RCV001579624;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374	5	112111309	112111310	T	TA	5:g.112111309_112111310insA	-
NM_000038.6(APC):c.423-4del	324	APC	Benign/Likely benign	rs730881230	RCV000159526\|RCV000202236\|RCV001353891\|RCV001520354\|RCV001762340;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0005575,MedGen:C0346629,OMIM:114500	5	112111310	112111310	TA	T	NC_000005.9:g.112111322del	ClinGen:CA009327	C0027672 Hereditary cancer-predisposing syndrome;
NC_000005.10:g.(?_112775617)_(112780913_?)del	324	APC	Pathogenic	-1	RCV001033570\|RCV001862458;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111314	112116610	na	na	-1	-
NC_000005.9:g.(?_112111314)_(112111444_?)del	324	APC	Pathogenic	-1	RCV001380904;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111314	112111444	na	na	-1	-
NC_000005.9:g.(?_112111314)_(112179823_?)dup	324	APC	Uncertain significance	-1	RCV002038955;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111314	112179823	na	na	-1	-
NC_000005.9:g.(?_112111314)_(112137090_?)del	324	APC	Pathogenic	-1	RCV001972495;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111314	112137090	na	na	-1	-
NC_000005.10:g.(?_112775619)_(112801393_?)del	324	APC	Pathogenic	-1	RCV000796140;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111316	112137090	na	na		-
NM_000038.6(APC):c.423-9A>G	324	APC	Pathogenic	rs1554071494	RCV000551256;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111317	112111317	A	G	NC_000005.9:g.112111317A>G	ClinGen:CA658657473	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.423-9A>T	324	APC	Likely benign	-1	RCV001481567;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111317	112111317	A	T	112111317	-
NM_000038.6(APC):c.423-8A>T	324	APC	Likely benign	-1	RCV001444720;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111318	112111318	A	T	112111318	-
NC_000005.10:g.(?_112775623)_(112844132_?)del	324	APC	Pathogenic	-1	RCV000527737\|RCV001853710;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111320	112179829	na	na		-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.423-6A>G	324	APC	Uncertain significance	-1	RCV001366684;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111320	112111320	A	G	112111320	-
NM_000038.6(APC):c.423-3_423-2del	324	APC	Conflicting interpretations of pathogenicity	rs863225354	RCV000201990\|RCV000467938\|RCV000775120\|RCV001705159;	N	MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202	5	112111322	112111323	AAT	A	5:g.112111322_112111323del	ClinGen:CA038361	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.423-4_423-2del	324	APC	Uncertain significance	rs876657408	RCV000185617\|RCV000471040;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111322	112111324	AAAT	A	NC_000005.9:g.112111322_112111324del	ClinGen:CA10575731,OMIM:611731.0052
NM_000038.6(APC):c.423-4A>G	324	APC	Uncertain significance	rs1561477594	RCV000702026\|RCV001022105;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112111322	112111322	A	G	NC_000005.9:g.112111322A>G	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.423-4A>T	324	APC	Likely benign	-1	RCV001489493;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111322	112111322	A	T	112111322	-
NM_000038.6(APC):c.423-3T>A	324	APC	Conflicting interpretations of pathogenicity	rs587782293	RCV000131175\|RCV000202091\|RCV000686573\|RCV001353717;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112111323	112111323	T	A	5:g.112111323T>A	ClinGen:CA009307	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.423-3T>C	324	APC	Uncertain significance	rs587782293	RCV000568909\|RCV001853754;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111323	112111323	T	C	NC_000005.9:g.112111323T>C	ClinGen:CA658657474	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.423-2A>T	324	APC	Pathogenic	rs879254087	RCV000235486\|RCV001857812;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111324	112111324	A	T	5:g.112111324A>T	ClinGen:CA10584236	CN517202 not provided;
NM_000038.6(APC):c.423-2A>C	324	APC	Pathogenic	-1	RCV001384461;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111324	112111324	A	C	112111324	-
NM_000038.6(APC):c.423-2A>G	324	APC	Pathogenic	-1	RCV001949653;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111324	112111324	A	G	112111324	-
NM_000038.6(APC):c.423-1G>A	324	APC	Pathogenic	rs397514031	RCV000000878\|RCV000491238\|RCV000502154\|RCV001762028\|RCV001851518;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202\|MONDO:MONDO:0005575,MedGen:C0346629,OMIM:114500\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111325	112111325	G	A	5:g.112111325G>A	ClinGen:CA009189,OMIM:611731.0043	CN240755 Familial adenomatous polyposis;
NM_000038.6(APC):c.423-1G>C	324	APC	Pathogenic	rs397514031	RCV000202202\|RCV001065895;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111325	112111325	G	C	NC_000005.9:g.112111325G>C	ClinGen:CA009194	CN517202 not provided;
NM_000038.6(APC):c.423G>T (p.Arg141Ser)	324	APC	Pathogenic	rs863224458	RCV000199388\|RCV000501209\|RCV001270008\|RCV001853212;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0002032,MedGen:C0699790\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111326	112111326	G	T	5:g.112111326G>T	ClinGen:CA338613	CN240755 Familial adenomatous polyposis;
NM_000038.6(APC):c.424_531+69dup	324	APC	Likely pathogenic	rs1561477658	RCV000691575;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111326	112111327	G	GTCATTGCTTCTTGCTGATCTTGACAAAGAAGAAAAGGAAAAAGACTGGTATTACGCTCAACTTCAGAATCTCACTAAAAGAATAGATAGTCTTCCTTTAACTGAAAATG	5:g.112111326_112111327insTCATTGCTTCTTGCTGATCTTGACAAAGAAGAAAAGGAAAAAGACTGGTATTACGCTCAACTTCAGAATCTCACTAAAAGAATAGATAGTCTTCCTTTA	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.423G>A (p.Arg141=)	324	APC	Uncertain significance	-1	RCV001967976;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111326	112111326	G	A	112111326	-
NM_000038.6(APC):c.424T>A (p.Ser142Thr)	324	APC	Uncertain significance	rs1311934641	RCV000708950;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111327	112111327	T	A	5:g.112111327T>A	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.426_427del (p.Leu143fs)	324	APC	Pathogenic	rs587782557	RCV000131775\|RCV000144571\|RCV000202026\|RCV000504124\|RCV000506761\|RCV001353612;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202\|MONDO:MONDO:0021055,MedGen:C0032580,OMIM:PS175100, Orphanet:733\|MedGen:CN169374\|MONDO:MONDO:0002032,MedGen:C0699790	5	112111329	112111330	CAT	C	5:g.112111329_112111330del	ClinGen:CA009418	CN240755 Familial adenomatous polyposis;
NM_000038.6(APC):c.432T>A (p.Leu144=)	324	APC	Likely benign	-1	RCV002193838;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111335	112111335	T	A	112111335	-
NM_000038.6(APC):c.436G>A (p.Ala146Thr)	324	APC	Uncertain significance	rs763181290	RCV001022370\|RCV001244840;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111339	112111339	G	A	5:g.112111339G>A	-
NM_000038.6(APC):c.436G>T (p.Ala146Ser)	324	APC	Uncertain significance	rs763181290	RCV001327305;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111339	112111339	G	T	112111339	-
NM_000038.6(APC):c.436G>C (p.Ala146Pro)	324	APC	Uncertain significance	-1	RCV001970469;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111339	112111339	G	C	112111339	-
NM_000038.6(APC):c.437C>T (p.Ala146Val)	324	APC	Uncertain significance	rs1305794169	RCV000566219\|RCV000780845\|RCV000700936;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111340	112111340	C	T	5:g.112111340C>T	ClinGen:CA16022277	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.437C>G (p.Ala146Gly)	324	APC	Uncertain significance	rs1305794169	RCV001241978;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111340	112111340	C	G	5:g.112111340C>G	-
NM_000038.6(APC):c.438T>C (p.Ala146=)	324	APC	Likely benign	-1	RCV001433025;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111341	112111341	T	C	112111341	-
NM_000038.6(APC):c.440dup (p.Asp147fs)	324	APC	Pathogenic	-1	RCV001996956;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111342	112111343	G	GA	112111342	-
NM_000038.6(APC):c.440A>G (p.Asp147Gly)	324	APC	Uncertain significance	rs769039873	RCV000235657\|RCV001022439\|RCV001338815;	N	MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111343	112111343	A	G	NC_000005.9:g.112111343A>G	ClinGen:CA038999	CN169374 not specified;
NM_000038.6(APC):c.440A>C (p.Asp147Ala)	324	APC	Uncertain significance	-1	RCV001966451;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111343	112111343	A	C	112111343	-
NM_000038.6(APC):c.442C>A (p.Leu148Ile)	324	APC	Uncertain significance	rs774964663	RCV000568928\|RCV001055952;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111345	112111345	C	A	NC_000005.9:g.112111345C>A	ClinGen:CA039051	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.442del (p.Asp149fs)	324	APC	Pathogenic	-1	RCV001354880;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111345	112111345	TC	T	112111344	-
NM_000038.6(APC):c.443T>A (p.Leu148His)	324	APC	Uncertain significance	rs762062860	RCV000220750\|RCV000689183;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111346	112111346	T	A	5:g.112111346T>A	ClinGen:CA039077	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.443T>G (p.Leu148Arg)	324	APC	Uncertain significance	rs762062860	RCV000819978;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111346	112111346	T	G	5:g.112111346T>G	-
NM_000038.6(APC):c.445G>C (p.Asp149His)	324	APC	Uncertain significance	rs767875993	RCV000563918\|RCV000794048;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111348	112111348	G	C	NC_000005.9:g.112111348G>C	ClinGen:CA039127	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.445G>A (p.Asp149Asn)	324	APC	Uncertain significance	rs767875993	RCV001022514\|RCV001352466;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111348	112111348	G	A	5:g.112111348G>A	-
NM_000038.6(APC):c.447C>A (p.Asp149Glu)	324	APC	Uncertain significance	rs750821213	RCV000461374\|RCV000561667;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112111350	112111350	C	A	NC_000005.9:g.112111350C>A	ClinGen:CA039179	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.447C>G (p.Asp149Glu)	324	APC	Uncertain significance	rs750821213	RCV001206047;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111350	112111350	C	G	5:g.112111350C>G	-
NM_000038.6(APC):c.450_453del (p.Glu151fs)	324	APC	Pathogenic	rs863225355	RCV000202178\|RCV001384462;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111351	112111354	CAAAG	C	NC_000005.9:g.112111353_112111356del	ClinGen:CA279775	CN517202 not provided;
NM_000038.6(APC):c.448A>T (p.Lys150Ter)	324	APC	Pathogenic	rs878853444	RCV000231021\|RCV000657600\|RCV001854815;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111351	112111351	A	T	NC_000005.9:g.112111351A>T	ClinGen:CA10582275	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.449A>G (p.Lys150Arg)	324	APC	Uncertain significance	rs371085910	RCV000130643\|RCV000148370\|RCV000206082\|RCV000211892\|RCV000656744;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0005484,MedGen:C1302401\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374\|MedGen:CN517202	5	112111352	112111352	A	G	5:g.112111352A>G	ClinGen:CA009591	C1302401 Colorectal adenoma;
NM_000038.6(APC):c.450A>G (p.Lys150=)	324	APC	Conflicting interpretations of pathogenicity	rs116020626	RCV000159527\|RCV000199795\|RCV000211893\|RCV000759433\|RCV001156933\|RCV001353868;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374\|MedGen:CN517202\|MedGen:CN239210\|MONDO:MONDO:0002032,MedGen:C0699790	5	112111353	112111353	A	G	NC_000005.9:g.112111353A>G	ClinGen:CA009598	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.453del (p.Glu152fs)	324	APC	Pathogenic	rs863224820	RCV000202272\|RCV000200847\|RCV000491770\|RCV001356072;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0002032,MedGen:C0699790	5	112111355	112111355	GA	G	NC_000005.9:g.112111356del	ClinGen:CA279814	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.454G>C (p.Glu152Gln)	324	APC	Uncertain significance	-1	RCV002045348;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111357	112111357	G	C	112111357	-
NM_000038.6(APC):c.458del (p.Lys153fs)	324	APC	Pathogenic	rs1554071521	RCV000503185\|RCV001385183;	N	MONDO:MONDO:0002032,MedGen:C0699790\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111358	112111358	GA	G	NC_000005.9:g.112111361del	ClinGen:CA645372773	CN240755 Familial adenomatous polyposis;
NM_000038.6(APC):c.457A>G (p.Lys153Glu)	324	APC	Uncertain significance	rs1561477861	RCV000704385;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111360	112111360	A	G	5:g.112111360A>G	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.457A>T (p.Lys153Ter)	324	APC	Pathogenic	-1	RCV001951273;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111360	112111360	A	T	112111360	-
NM_000038.6(APC):c.458A>G (p.Lys153Arg)	324	APC	Uncertain significance	rs754553913	RCV000561950\|RCV000700039;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111361	112111361	A	G	NC_000005.9:g.112111361A>G	ClinGen:CA039423	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.460dup (p.Glu154fs)	324	APC	Pathogenic	-1	RCV001726722;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111361	112111362	A	AG	112111361	-
NM_000038.6(APC):c.459G>A (p.Lys153=)	324	APC	Likely benign	rs864622482	RCV000205338\|RCV000570963\|RCV000614961;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	5	112111362	112111362	G	A	NC_000005.9:g.112111362G>A	ClinGen:CA349496	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.460G>A (p.Glu154Lys)	324	APC	Uncertain significance	rs786202822	RCV000165838\|RCV000479967\|RCV000708951;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111363	112111363	G	A	5:g.112111363G>A	ClinGen:CA009636	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.465del (p.Asp156fs)	324	APC	Pathogenic	rs1554071529	RCV000562556\|RCV001055575;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111364	112111364	GA	G	5:g.112111364_112111364del	ClinGen:CA658657475	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.461A>G (p.Glu154Gly)	324	APC	Uncertain significance	rs1561477912	RCV000697285;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111364	112111364	A	G	5:g.112111364A>G	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.465A>G (p.Lys155=)	324	APC	Likely benign	rs778691867	RCV000461064\|RCV000776475\|RCV001721463;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202	5	112111368	112111368	A	G	5:g.112111368A>G	ClinGen:CA039516	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.466G>C (p.Asp156His)	324	APC	Uncertain significance	rs1554071538	RCV000584639\|RCV001853892;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111369	112111369	G	C	5:g.112111369G>C	ClinGen:CA16022340	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.466G>T (p.Asp156Tyr)	324	APC	Uncertain significance	rs1554071538	RCV000807496;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111369	112111369	G	T	5:g.112111369G>T	-
NM_000038.6(APC):c.466G>A (p.Asp156Asn)	324	APC	Uncertain significance	rs1554071538	RCV001245359;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111369	112111369	G	A	5:g.112111369G>A	-
NM_000038.6(APC):c.468C>T (p.Asp156=)	324	APC	Likely benign	rs752627126	RCV000234653\|RCV001022898;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112111371	112111371	C	T	5:g.112111371C>T	ClinGen:CA10582276	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.468C>G (p.Asp156Glu)	324	APC	Uncertain significance	rs752627126	RCV000540160\|RCV000567343\|RCV001193497;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	5	112111371	112111371	C	G	NC_000005.9:g.112111371C>G	ClinGen:CA039593	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.468C>A (p.Asp156Glu)	324	APC	Uncertain significance	-1	RCV002013016;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111371	112111371	C	A	112111371	-
NM_000038.6(APC):c.470G>A (p.Trp157Ter)	324	APC	Pathogenic	rs137854576	RCV000000852;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111373	112111373	G	A	5:g.112111373G>A	ClinGen:CA009701,OMIM:611731.0021	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.471G>A (p.Trp157Ter)	324	APC	Pathogenic	rs1060503328	RCV000458690\|RCV000583237;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112111374	112111374	G	A	NC_000005.9:g.112111374G>A	ClinGen:CA16022351	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.471G>C (p.Trp157Cys)	324	APC	Uncertain significance	rs1060503328	RCV001308703;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111374	112111374	G	C	112111374	-
NM_000038.6(APC):c.473A>T (p.Tyr158Phe)	324	APC	Uncertain significance	rs587782477	RCV000131591\|RCV000457825;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111376	112111376	A	T	5:g.112111376A>T	ClinGen:CA009722	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.475dup (p.Tyr159fs)	324	APC	Pathogenic	rs863225361	RCV000202290\|RCV000568959\|RCV000694158;	N	MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111376	112111377	A	AT	NC_000005.9:g.112111378dup	ClinGen:CA279827	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.474T>C (p.Tyr158=)	324	APC	Likely benign	rs1060504891	RCV000475351\|RCV001424228;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111377	112111377	T	C	NC_000005.9:g.112111377T>C	ClinGen:CA16611641	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.474T>A (p.Tyr158Ter)	324	APC	Pathogenic	-1	RCV001993320;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111377	112111377	T	A	112111377	-
NM_000038.6(APC):c.476dup (p.Tyr159Ter)	324	APC	Pathogenic/Likely pathogenic	rs878853451	RCV000229992\|RCV000486696;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112111378	112111379	T	TA	5:g.112111378_112111379insA	ClinGen:CA10582277	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.475T>C (p.Tyr159His)	324	APC	Uncertain significance	-1	RCV001959538;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111378	112111378	T	C	112111378	-
NM_000038.6(APC):c.476_488del (p.Tyr158_Tyr159insTer)	324	APC	Pathogenic	-1	RCV001384864;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111379	112111391	TACGCTCAACTTCA	T	112111378	-
NM_000038.6(APC):c.477del (p.Tyr158_Tyr159insTer)	324	APC	Pathogenic	rs730880250	RCV000157585\|RCV000657827;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112111380	112111380	AC	A	5:g.112111380_112111380del	ClinGen:CA009748	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.477C>T (p.Tyr159=)	324	APC	Likely benign	rs863224281	RCV000198065\|RCV000438858\|RCV000564772;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112111380	112111380	C	T	NC_000005.9:g.112111380C>T	ClinGen:CA337609	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.477C>G (p.Tyr159Ter)	324	APC	Pathogenic	rs863224281	RCV000236674\|RCV000646369\|RCV001023029\|RCV001844100;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021055,MedGen:C0032580,OMIM:PS175100, Orphanet:733	5	112111380	112111380	C	G	NC_000005.9:g.112111380C>G	ClinGen:CA10584237	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.478G>A (p.Ala160Thr)	324	APC	Uncertain significance	rs1114167556	RCV000490878\|RCV000529546\|RCV001550818;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112111381	112111381	G	A	NC_000005.9:g.112111381G>A	ClinGen:CA16022368	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.481C>T (p.Gln161Ter)	324	APC	Pathogenic	rs876658325	RCV000221156\|RCV000467000\|RCV001269625;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112111384	112111384	C	T	5:g.112111384C>T	ClinGen:CA10578293	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.483A>G (p.Gln161=)	324	APC	Likely benign	rs1554071578	RCV000581424\|RCV000975503;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111386	112111386	A	G	NC_000005.9:g.112111386A>G	ClinGen:CA445753054	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.484C>A (p.Leu162Ile)	324	APC	Uncertain significance	-1	RCV001884093;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111387	112111387	C	A	112111387	-
NM_000038.6(APC):c.487C>T (p.Gln163Ter)	324	APC	Pathogenic	rs863225362	RCV000202083\|RCV000500940\|RCV000548404\|RCV001023190;	N	MedGen:CN517202\|MONDO:MONDO:0021055,MedGen:C0032580,OMIM:PS175100, Orphanet:733\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112111390	112111390	C	T	NC_000005.9:g.112111390C>T	ClinGen:CA279721	CN240755 Familial adenomatous polyposis;
NM_000038.6(APC):c.489G>A (p.Gln163=)	324	APC	Likely benign	rs876660717	RCV000942020\|RCV001483427;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111392	112111392	G	A	5:g.112111392G>A	-
NM_000038.6(APC):c.490A>G (p.Asn164Asp)	324	APC	Uncertain significance	-1	RCV001932871;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111393	112111393	A	G	112111393	-
NM_000038.6(APC):c.492T>C (p.Asn164=)	324	APC	Likely benign	-1	RCV001420068;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111395	112111395	T	C	112111395	-
NM_000038.6(APC):c.495C>T (p.Leu165=)	324	APC	Likely benign	rs1554071591	RCV000646570;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111398	112111398	C	T	5:g.112111398C>T	ClinGen:CA445753062	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.496A>G (p.Thr166Ala)	324	APC	Uncertain significance	rs889134189	RCV000699460\|RCV001023341;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112111399	112111399	A	G	5:g.112111399A>G	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.496A>T (p.Thr166Ser)	324	APC	Uncertain significance	rs889134189	RCV000695295;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111399	112111399	A	T	5:g.112111399A>T	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.497_499delinsTT (p.Thr166fs)	324	APC	Pathogenic	rs1114167588	RCV000491467\|RCV000694736;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111400	112111402	CTA	TT	NC_000005.9:g.112111400_112111402delinsTT	ClinGen:CA645369351	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.497C>T (p.Thr166Ile)	324	APC	Uncertain significance	-1	RCV002012112;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111400	112111400	C	T	112111400	-
NM_000038.6(APC):c.499A>G (p.Lys167Glu)	324	APC	Uncertain significance	rs1310352139	RCV000646309\|RCV001524942;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112111402	112111402	A	G	NC_000005.9:g.112111402A>G	ClinGen:CA16022414	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.500A>G (p.Lys167Arg)	324	APC	Uncertain significance	-1	RCV001931523;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111403	112111403	A	G	112111403	-
NM_000038.6(APC):c.503G>A (p.Arg168Lys)	324	APC	Uncertain significance	rs1554071604	RCV000539330\|RCV001178548;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112111406	112111406	G	A	NC_000005.9:g.112111406G>A	ClinGen:CA16022423	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.505_507del (p.Ile169del)	324	APC	Uncertain significance	-1	RCV002018058;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111407	112111409	GAAT	G	112111406	-
NM_000038.6(APC):c.509_512del (p.Asp170fs)	324	APC	Pathogenic	rs387906231	RCV000000841\|RCV000201968\|RCV000491548\|RCV001797583;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021055,MedGen:C0032580,OMIM:PS175100, Orphanet:733	5	112111408	112111411	AATAG	A	5:g.112111408_112111411del	ClinGen:CA009858,OMIM:611731.0012	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.505A>G (p.Ile169Val)	324	APC	Uncertain significance	rs878853455	RCV000227519\|RCV000562601\|RCV001854819;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111408	112111408	A	G	NC_000005.9:g.112111408A>G	ClinGen:CA10582278	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.506T>C (p.Ile169Thr)	324	APC	Uncertain significance	rs1757567981	RCV001201299\|RCV001859218;	N	MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111409	112111409	T	C	5:g.112111409T>C	-
NM_000038.6(APC):c.508_509del (p.Ile169_Asp170insTer)	324	APC	Pathogenic/Likely pathogenic	rs886039642	RCV000255777\|RCV000694331;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111410	112111411	TAG	T	5:g.112111410_112111411del	ClinGen:CA10588376	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.512G>A (p.Ser171Asn)	324	APC	Uncertain significance	rs1157254183	RCV000775321\|RCV001215219;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111415	112111415	G	A	NC_000005.9:g.112111415G>A	-
NM_000038.6(APC):c.516dup (p.Pro173fs)	324	APC	Pathogenic	rs1580359575	RCV000805446;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111417	112111418	C	CT	5:g.112111417_112111418insT	-
NM_000038.6(APC):c.514C>A (p.Leu172Ile)	324	APC	Uncertain significance	-1	RCV001974367;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111417	112111417	C	A	112111417	-
NM_000038.6(APC):c.516del (p.Pro173fs)	324	APC	Pathogenic	-1	RCV001383961;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111418	112111418	CT	C	112111417	-
NM_000038.6(APC):c.516T>C (p.Leu172=)	324	APC	Likely benign	rs777643585	RCV000461763\|RCV000580075;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112111419	112111419	T	C	NC_000005.9:g.112111419T>C	ClinGen:CA040814	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.520T>C (p.Leu174=)	324	APC	Likely benign	-1	RCV001473524;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111423	112111423	T	C	112111423	-
NM_000038.6(APC):c.524_531+4del	324	APC	Pathogenic/Likely pathogenic	rs863225364	RCV000202212\|RCV000568686\|RCV000707133;	N	MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111424	112111435	TTAACTGAAAATG	T	NC_000005.9:g.112111427_112111438del	ClinGen:CA279786	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.521T>G (p.Leu174Ter)	324	APC	Pathogenic	rs1757571583	RCV001052876;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111424	112111424	T	G	5:g.112111424T>G	-
NM_000038.6(APC):c.522_523del (p.Leu174fs)	324	APC	Pathogenic	rs1757572270	RCV001055879;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111425	112111426	TAA	T	5:g.112111425_112111426del	-
NM_000038.6(APC):c.524C>G (p.Thr175Ser)	324	APC	Uncertain significance	rs1554071616	RCV000646477;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111427	112111427	C	G	5:g.112111427C>G	ClinGen:CA16022473	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.526G>C (p.Glu176Gln)	324	APC	Uncertain significance	-1	RCV002026921;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111429	112111429	G	C	112111429	-
NM_000038.6(APC):c.527A>C (p.Glu176Ala)	324	APC	Uncertain significance	rs1580359661	RCV001023849\|RCV001320814;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111430	112111430	A	C	5:g.112111430A>C	-
NM_000038.6(APC):c.530del (p.Asn177fs)	324	APC	Pathogenic	rs1757573424	RCV001064215;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111430	112111430	GA	G	5:g.112111430_112111430del	-
NM_000038.6(APC):c.527A>G (p.Glu176Gly)	324	APC	Uncertain significance	-1	RCV001915741;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111430	112111430	A	G	112111430	-
NM_000038.6(APC):c.530A>G (p.Asn177Ser)	324	APC	Uncertain significance	rs1561478485	RCV000773905\|RCV001350446;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111433	112111433	A	G	NC_000005.9:g.112111433A>G	-
NM_000038.6(APC):c.531T>C (p.Asn177=)	324	APC	Uncertain significance	rs1234730026	RCV001317089;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111434	112111434	T	C	112111434	-
NM_000038.6(APC):c.531+1G>C	324	APC	Pathogenic/Likely pathogenic	rs876659973	RCV000217536\|RCV000411683\|RCV000482581;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112111435	112111435	G	C	5:g.112111435G>C	ClinGen:CA10578295	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.531+2dup	324	APC	Pathogenic	rs1060503257	RCV000458186;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111435	112111436	G	GT	NC_000005.9:g.112111436dup	ClinGen:CA16611556	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.531+5_531+8del	324	APC	Likely pathogenic	rs1554071617	RCV000646455;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111435	112111438	TGTAA	T	NC_000005.9:g.112111435GTAA[1]	ClinGen:CA658760464	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.531+1G>A	324	APC	Pathogenic/Likely pathogenic	rs876659973	RCV001066456;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111435	112111435	G	A	5:g.112111435G>A	-
NM_000038.6(APC):c.531+2T>A	324	APC	Pathogenic/Likely pathogenic	rs863225365	RCV000202121\|RCV000491613\|RCV001203374\|RCV001193574;	N	MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021055,MedGen:C0032580,OMIM:PS175100, Orphanet:733	5	112111436	112111436	T	A	NC_000005.9:g.112111436T>A	ClinGen:CA279737	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.531+2T>C	324	APC	Pathogenic	rs863225365	RCV000202262\|RCV000563395\|RCV001853251;	N	MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111436	112111436	T	C	NC_000005.9:g.112111436T>C	ClinGen:CA279807	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.531+3A>C	324	APC	Likely pathogenic	rs1114167550	RCV000491509\|RCV000646317;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111437	112111437	A	C	NC_000005.9:g.112111437A>C	ClinGen:CA645369352	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.531+3A>T	324	APC	Uncertain significance	-1	RCV001873044;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111437	112111437	A	T	112111437	-
NM_000038.6(APC):c.531+4A>G	324	APC	Uncertain significance	-1	RCV001970530;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111438	112111438	A	G	112111438	-
NM_000038.6(APC):c.531+5G>C	324	APC	Pathogenic	rs587779798	RCV000322468\|RCV000491896\|RCV000542745;	N	MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111439	112111439	G	C	5:g.112111439G>C	ClinGen:CA10602909	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.531+6T>C	324	APC	Uncertain significance	rs1561478536	RCV000699407;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111440	112111440	T	C	5:g.112111440T>C	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.531+9C>G	324	APC	Uncertain significance	rs1554071622	RCV000590516\|RCV000776342\|RCV001242284;	N	MedGen:CN517202\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111443	112111443	C	G	5:g.112111443C>G	ClinGen:CA658683401	CN517202 not provided;
NM_000038.6(APC):c.531+16G>A	324	APC	Likely benign	rs770126046	RCV000428322\|RCV000580247\|RCV000662543;	N	MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112111450	112111450	G	A	5:g.112111450G>A	ClinGen:CA041353	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.10:g.(?_112779849)_(112844136_?)dup	324	APC	Uncertain significance	-1	RCV001033218\|RCV001873437;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112115546	112179833	na	na	-1	-
NM_000038.6(APC):c.532-939G>A	324	APC	Likely benign	rs551489857	RCV000409642;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112115548	112115548	G	A	5:g.112115548G>A	ClinGen:CA16042085	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.532-939G>T	324	APC	Likely benign	rs551489857	RCV000412192;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112115548	112115548	G	T	NC_000005.9:g.112115548G>T	ClinGen:CA16042086	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.532-14_532-12del	324	APC	Likely benign	rs765893314	RCV000581877\|RCV001353825\|RCV001722422;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112116468	112116470	TTTA	T	NC_000005.9:g.112116470ATT[1]	ClinGen:CA041434	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.532-17A>T	324	APC	Likely benign	rs997606437	RCV000408966\|RCV000439871\|RCV000580653;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112116470	112116470	A	T	NC_000005.9:g.112116470A>T	ClinGen:CA16042087	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.532-14A>T	324	APC	Likely benign	rs375254915	RCV000582879\|RCV002060567;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116473	112116473	A	T	5:g.112116473A>T	ClinGen:CA041407	C0027672 Hereditary cancer-predisposing syndrome;
NM_000038.6(APC):c.532-14A>G	324	APC	Likely benign	-1	RCV002110615;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116473	112116473	A	G	112116473	-
NM_000038.6(APC):c.532-10G>A	324	APC	Likely benign	-1	RCV002142942;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116477	112116477	G	A	112116477	-
NM_000038.6(APC):c.532-10G>C	324	APC	Likely benign	-1	RCV002174636;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116477	112116477	G	C	112116477	-
NM_000038.6(APC):c.532-9del	324	APC	Likely benign	rs777844116	RCV000583887\|RCV000646634;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116478	112116478	GT	G	5:g.112116478_112116478del	ClinGen:CA041581	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.532-8G>A	324	APC	Pathogenic/Likely pathogenic	rs1060503323	RCV000458868\|RCV000503571\|RCV000491376;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0002032,MedGen:C0699790\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112116479	112116479	G	A	NC_000005.9:g.112116479G>A	ClinGen:CA16611747	CN240755 Familial adenomatous polyposis;
NM_000038.6(APC):c.532-8G>C	324	APC	Likely benign	-1	RCV002203863;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116479	112116479	G	C	112116479	-
NM_000038.6(APC):c.532-7G>C	324	APC	Likely benign	rs1057520840	RCV000460487\|RCV000579458\|RCV001720052;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202	5	112116480	112116480	G	C	5:g.112116480G>C	ClinGen:CA16604648	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.532-7G>T	324	APC	Likely benign	rs1057520840	RCV000646589\|RCV001191941;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112116480	112116480	G	T	5:g.112116480G>T	ClinGen:CA561895117	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.532-6T>C	324	APC	Uncertain significance	rs1554072543	RCV000543401\|RCV001775867;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112116481	112116481	T	C	NC_000005.9:g.112116481T>C	ClinGen:CA658657477	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.9:g.(?_112116481)_(112179829_?)dup	324	APC	Uncertain significance	-1	RCV000646698;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116481	112179829	na	na		-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.532-2A>G	324	APC	Likely pathogenic	rs752152148	RCV000646510;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116485	112116485	A	G	NC_000005.9:g.112116485A>G	ClinGen:CA360617494	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.532-2A>C	324	APC	Pathogenic	rs752152148	RCV000824411;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116485	112116485	A	C	5:g.112116485A>C	-
NM_000038.6(APC):c.532-2A>T	324	APC	Pathogenic	-1	RCV001975132;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116485	112116485	A	T	112116485	-
NM_000038.6(APC):c.532-1G>A	324	APC	Pathogenic	rs1554072547	RCV000506699\|RCV000646378;	N	MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116486	112116486	G	A	5:g.112116486G>A	ClinGen:CA360617495	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.532T>A (p.Phe178Ile)	324	APC	Uncertain significance	rs1060503344	RCV000465632\|RCV001002492\|RCV001180356\|RCV001753909;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202	5	112116487	112116487	T	A	5:g.112116487T>A	ClinGen:CA16022491	C2713442 175100 Familial adenomatous polyposis 1;
NC_000005.10:g.(?_112780790)_(112846239_?)del	324	APC	Pathogenic	-1	RCV000476663;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116487	112181936	na	na		-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.535T>G (p.Ser179Ala)	324	APC	Uncertain significance	-1	RCV001929162;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116490	112116490	T	G	112116490	-
NM_000038.6(APC):c.537del (p.Leu180fs)	324	APC	Pathogenic	-1	RCV001384463;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116491	112116491	TC	T	112116490	-
NM_000038.6(APC):c.537C>A (p.Ser179=)	324	APC	Likely benign	rs149736402	RCV000167064\|RCV000469176\|RCV000587471;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN169374	5	112116492	112116492	C	A	5:g.112116492C>A	ClinGen:CA010363	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.539T>C (p.Leu180Ser)	324	APC	Uncertain significance	-1	RCV002030092;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116494	112116494	T	C	112116494	-
NM_000038.6(APC):c.543_546del (p.Thr182fs)	324	APC	Pathogenic	rs1554072562	RCV000533678;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116495	112116498	TACAA	T	NC_000005.9:g.112116498_112116501del	ClinGen:CA645546029	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.540A>G (p.Leu180=)	324	APC	Likely benign	-1	RCV001506836;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116495	112116495	A	G	112116495	-
NM_000038.6(APC):c.541C>G (p.Gln181Glu)	324	APC	Uncertain significance	rs863225366	RCV001351852;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116496	112116496	C	G	112116496	-
NM_000038.6(APC):c.546A>G (p.Thr182=)	324	APC	Likely benign	rs864622392	RCV000206443\|RCV001394400;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116501	112116501	A	G	NC_000005.9:g.112116501A>G	ClinGen:CA350474	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.547_548del (p.Asp183fs)	324	APC	Pathogenic	rs1758238807	RCV001212162\|RCV001358573;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112116501	112116502	CAG	C	5:g.112116501_112116502del	-
NM_000038.6(APC):c.547G>C (p.Asp183His)	324	APC	Uncertain significance	rs1758239055	RCV001207066;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116502	112116502	G	C	5:g.112116502G>C	-
NM_000038.6(APC):c.548A>T (p.Asp183Val)	324	APC	Uncertain significance	rs1758239334	RCV001210480;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116503	112116503	A	T	5:g.112116503A>T	-
NM_000038.6(APC):c.551T>C (p.Met184Thr)	324	APC	Uncertain significance	rs1257143633	RCV000582295\|RCV000646314\|RCV001775905;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN517202	5	112116506	112116506	T	C	5:g.112116506T>C	ClinGen:CA16022537	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.552G>T (p.Met184Ile)	324	APC	Uncertain significance	rs1758240617	RCV001228491;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116507	112116507	G	T	5:g.112116507G>T	-
NM_000038.6(APC):c.552G>A (p.Met184Ile)	324	APC	Uncertain significance	-1	RCV001372377;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116507	112116507	G	A	112116507	-
NM_000038.6(APC):c.554C>T (p.Thr185Ile)	324	APC	Uncertain significance	rs1484797510	RCV001058069;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116509	112116509	C	T	5:g.112116509C>T	-
NM_000038.6(APC):c.555C>G (p.Thr185=)	324	APC	Likely benign	rs1287296038	RCV000932337\|RCV001408739;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116510	112116510	C	G	5:g.112116510C>G	-
NM_000038.6(APC):c.556A>G (p.Arg186Gly)	324	APC	Uncertain significance	rs1580379633	RCV001024286\|RCV001236397;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116511	112116511	A	G	5:g.112116511A>G	-
NM_000038.6(APC):c.557G>C (p.Arg186Thr)	324	APC	Uncertain significance	rs1561485438	RCV000708952;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116512	112116512	G	C	5:g.112116512G>C	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.559del (p.Arg187fs)	324	APC	Pathogenic	rs1758242304	RCV001068749;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116513	112116513	GA	G	5:g.112116513_112116513del	-
NM_000038.6(APC):c.560G>A (p.Arg187Lys)	324	APC	Uncertain significance	rs1758242583	RCV001299691;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116515	112116515	G	A	112116515	-
NM_000038.6(APC):c.564A>G (p.Gln188=)	324	APC	Conflicting interpretations of pathogenicity	rs377493489	RCV000163065\|RCV000428165\|RCV000469275;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116519	112116519	A	G	5:g.112116519A>G	ClinGen:CA010565	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.565T>C (p.Leu189=)	324	APC	Likely benign	rs762146761	RCV000475660\|RCV000562278\|RCV000588432;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	5	112116520	112116520	T	C	NC_000005.9:g.112116520T>C	ClinGen:CA16611642	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.567G>C (p.Leu189Phe)	324	APC	Uncertain significance	rs1554072586	RCV000536999;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116522	112116522	G	C	NC_000005.9:g.112116522G>C	ClinGen:CA16022574	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.572_573dup (p.Glu192fs)	324	APC	Pathogenic	rs1758244651	RCV001044297;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116524	112116525	A	AAT	5:g.112116524_112116525insAT	-
NM_000038.6(APC):c.573T>C (p.Tyr191=)	324	APC	Benign/Likely benign	rs185154886	RCV000197836\|RCV000309947\|RCV000426052\|RCV000573062\|RCV001701788;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MedGen:CN239210\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202	5	112116528	112116528	T	C	5:g.112116528T>C	ClinGen:CA042785	CN239210 APC-Associated Polyposis Disorders;
NM_000038.6(APC):c.578C>G (p.Ala193Gly)	324	APC	Uncertain significance	rs780403698	RCV000702800;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116533	112116533	C	G	5:g.112116533C>G	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.580A>G (p.Arg194Gly)	324	APC	Uncertain significance	rs1758246384	RCV001238220;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116535	112116535	A	G	5:g.112116535A>G	-
NM_000038.6(APC):c.581G>C (p.Arg194Thr)	324	APC	Uncertain significance	rs200740020	RCV001245072;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116536	112116536	G	C	5:g.112116536G>C	-
NM_000038.6(APC):c.582G>A (p.Arg194=)	324	APC	Likely benign	rs864622103	RCV000206184\|RCV000573330\|RCV001193498;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	5	112116537	112116537	G	A	NC_000005.9:g.112116537G>A	ClinGen:CA350246	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.583C>T (p.Gln195Ter)	324	APC	Pathogenic	rs749479682	RCV000484402\|RCV001071166;	N	MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116538	112116538	C	T	5:g.112116538C>T	ClinGen:CA16022611	CN517202 not provided;
NM_000038.6(APC):c.583C>G (p.Gln195Glu)	324	APC	Uncertain significance	rs749479682	RCV000646275;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116538	112116538	C	G	NC_000005.9:g.112116538C>G	ClinGen:CA043181	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.584A>T (p.Gln195Leu)	324	APC	Uncertain significance	-1	RCV001947664;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116539	112116539	A	T	112116539	-
NM_000038.6(APC):c.586A>G (p.Ile196Val)	324	APC	Uncertain significance	rs1580379926	RCV001024624\|RCV001338379;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116541	112116541	A	G	5:g.112116541A>G	-
NM_000038.6(APC):c.588C>T (p.Ile196=)	324	APC	Likely benign	rs147846364	RCV000223661\|RCV000679072\|RCV001080456;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN517202\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116543	112116543	C	T	5:g.112116543C>T	ClinGen:CA043300	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.589A>G (p.Arg197Gly)	324	APC	Uncertain significance	rs1561485645	RCV000698205;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116544	112116544	A	G	5:g.112116544A>G	-	C2713442 175100 Familial adenomatous polyposis 1;
NM_000038.6(APC):c.591A>T (p.Arg197Ser)	324	APC	Uncertain significance	rs1758249528	RCV001240059;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116546	112116546	A	T	5:g.112116546A>T	-
NM_000038.6(APC):c.592G>A (p.Val198Ile)	324	APC	Uncertain significance	rs1168791940	RCV000614285\|RCV001046918\|RCV001024694;	N	MedGen:CN169374\|MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	112116547	112116547	G	A	NC_000005.9:g.112116547G>A	ClinGen:CA16022630	CN169374 not specified;
NM_000038.6(APC):c.593T>C (p.Val198Ala)	324	APC	Uncertain significance	-1	RCV001884746;	N	MONDO:MONDO:0021056,MedGen:C2713442,OMIM:175100	5	112116548	112116548	T	C	112116548	-
NM_000038.6(APC):c.595dup (p.Ala199fs)	324	APC